Prasad Jallepalli, MD, PhD
@prasad.bsky.social
Prof & Lab Head in NYC. 100% research: cell division, genome integrity, cancer.
Curious to a fault. Also πολύτροπος. Talking here for me alone. I listen to the finest worksong. Like/repost = bookmark/news, not agreement/endorsement.
Curious to a fault. Also πολύτροπος. Talking here for me alone. I listen to the finest worksong. Like/repost = bookmark/news, not agreement/endorsement.
Reposted by Prasad Jallepalli, MD, PhD
Mark Kelly says Pete Hegseth's reported double tap strike on a boat "seems to" be a war crime, and adds, "if what has been reported is accurate, I've got serious concerns about anybody in that chain of command stepping over a line that they should never step over. We are not Russia. We are not Iraq"
November 30, 2025 at 2:28 PM
Mark Kelly says Pete Hegseth's reported double tap strike on a boat "seems to" be a war crime, and adds, "if what has been reported is accurate, I've got serious concerns about anybody in that chain of command stepping over a line that they should never step over. We are not Russia. We are not Iraq"
it’s worth noting that the FDA official in question has never been a Principal Investigator on an NIH grant, despite having a physician-scientist appointment at UCSF
such shortcomings in leadership and scientific acumen are red flags for promotion — yet they didn’t dissuade RFK Jr. for some reason
such shortcomings in leadership and scientific acumen are red flags for promotion — yet they didn’t dissuade RFK Jr. for some reason
Finally got around to reading Prasad's actual memo about the purported deaths in children from COVID-19 vaccines, and it's kind of amazing in the worst ways possible.
At one point, he says (regarding rare adverse events):
"Causality is easy to assess in a randomized trial..."
At one point, he says (regarding rare adverse events):
"Causality is easy to assess in a randomized trial..."
November 30, 2025 at 10:02 AM
it’s worth noting that the FDA official in question has never been a Principal Investigator on an NIH grant, despite having a physician-scientist appointment at UCSF
such shortcomings in leadership and scientific acumen are red flags for promotion — yet they didn’t dissuade RFK Jr. for some reason
such shortcomings in leadership and scientific acumen are red flags for promotion — yet they didn’t dissuade RFK Jr. for some reason
Reposted by Prasad Jallepalli, MD, PhD
I feel like one of the most underrated explanations for what's happening right now in global politics is that almost everyone has lost their minds.
November 30, 2025 at 2:59 AM
I feel like one of the most underrated explanations for what's happening right now in global politics is that almost everyone has lost their minds.
Leo quoting his faith's scriptures: "whoever does not love, does not know God"
seems obvious to me, despite the supposed gulf in traditions
these days it seems like the main split is between those who have a moral and ethical compass and those who don't and/or claim said compass isn't working
seems obvious to me, despite the supposed gulf in traditions
these days it seems like the main split is between those who have a moral and ethical compass and those who don't and/or claim said compass isn't working
“We live in a world where religion is too often used to justify wars and atrocities.”
Pope Leo XIV in Istanbul
Pope Leo XIV in Istanbul
November 30, 2025 at 7:55 AM
Leo quoting his faith's scriptures: "whoever does not love, does not know God"
seems obvious to me, despite the supposed gulf in traditions
these days it seems like the main split is between those who have a moral and ethical compass and those who don't and/or claim said compass isn't working
seems obvious to me, despite the supposed gulf in traditions
these days it seems like the main split is between those who have a moral and ethical compass and those who don't and/or claim said compass isn't working
In a sincere attempt to lighten the mood of this account, I am delighted to celebrate this marvelous brew from @firestonewalker.bsky.social called “Wookey Jack”
It’s a black rye IPA recommended to me by a dear friend and beer whisperer
IMO it’s terrific — very dry and complex but never cloying
It’s a black rye IPA recommended to me by a dear friend and beer whisperer
IMO it’s terrific — very dry and complex but never cloying
November 30, 2025 at 7:09 AM
In a sincere attempt to lighten the mood of this account, I am delighted to celebrate this marvelous brew from @firestonewalker.bsky.social called “Wookey Jack”
It’s a black rye IPA recommended to me by a dear friend and beer whisperer
IMO it’s terrific — very dry and complex but never cloying
It’s a black rye IPA recommended to me by a dear friend and beer whisperer
IMO it’s terrific — very dry and complex but never cloying
I’ve lived in a blended multiracial and multiethnic family for decades, and know many others with their own take on this deeply American holiday
this is Whitesgiving and it’s sad
this is Whitesgiving and it’s sad
Karoline Leavitt's Thanksgiving spread. Please dissect.
www.dailymail.co.uk/news/article...
www.dailymail.co.uk/news/article...
November 30, 2025 at 4:27 AM
I’ve lived in a blended multiracial and multiethnic family for decades, and know many others with their own take on this deeply American holiday
this is Whitesgiving and it’s sad
this is Whitesgiving and it’s sad
Our experiment in self-governance cannot last if this is fruit: www.nytimes.com/2025/11/29/u...
November 30, 2025 at 3:58 AM
Our experiment in self-governance cannot last if this is fruit: www.nytimes.com/2025/11/29/u...
Reposted by Prasad Jallepalli, MD, PhD
19 year old freshman just wants to go home for Thanksgiving to see her family, she gets deported to Honduras.
Former President of Honduras who’s serving 45 years in prison for drug trafficking?
He gets a full presidential pardon.
Both are Honduran. Only one is a criminal.
Former President of Honduras who’s serving 45 years in prison for drug trafficking?
He gets a full presidential pardon.
Both are Honduran. Only one is a criminal.
November 29, 2025 at 8:27 PM
19 year old freshman just wants to go home for Thanksgiving to see her family, she gets deported to Honduras.
Former President of Honduras who’s serving 45 years in prison for drug trafficking?
He gets a full presidential pardon.
Both are Honduran. Only one is a criminal.
Former President of Honduras who’s serving 45 years in prison for drug trafficking?
He gets a full presidential pardon.
Both are Honduran. Only one is a criminal.
Reposted by Prasad Jallepalli, MD, PhD
President Trump, I am calling on you to fire Secretary Kennedy immediately.
He has contributed to this measles outbreak by spreading falsehoods about vaccines.
His reckless rhetoric will cost lives.
He has contributed to this measles outbreak by spreading falsehoods about vaccines.
His reckless rhetoric will cost lives.
November 29, 2025 at 4:38 PM
President Trump, I am calling on you to fire Secretary Kennedy immediately.
He has contributed to this measles outbreak by spreading falsehoods about vaccines.
His reckless rhetoric will cost lives.
He has contributed to this measles outbreak by spreading falsehoods about vaccines.
His reckless rhetoric will cost lives.
Reposted by Prasad Jallepalli, MD, PhD
The mayor of Akron, Ohio. 👏🏻👏🏻👏🏻
November 30, 2025 at 12:22 AM
The mayor of Akron, Ohio. 👏🏻👏🏻👏🏻
the children failed to learn the profound and beautiful lesson experienced and exemplified by their parents
these children enjoy whole and redeemed lives because America evolved from “was” to “is” in fits and starts
to have a perpetual underclass, to never accept the stranger, is intolerable
these children enjoy whole and redeemed lives because America evolved from “was” to “is” in fits and starts
to have a perpetual underclass, to never accept the stranger, is intolerable
Noone, in any position, can treat people this way. I truly fail to understand what is happening. From children of immigrants who at the time were considered from “shithole countries”.
November 30, 2025 at 2:42 AM
the children failed to learn the profound and beautiful lesson experienced and exemplified by their parents
these children enjoy whole and redeemed lives because America evolved from “was” to “is” in fits and starts
to have a perpetual underclass, to never accept the stranger, is intolerable
these children enjoy whole and redeemed lives because America evolved from “was” to “is” in fits and starts
to have a perpetual underclass, to never accept the stranger, is intolerable
Reposted by Prasad Jallepalli, MD, PhD
I have friends who have children with neurodevelopmental challenges, or come from various cultures with particular dress codes. This sickens me, in addition to piggy and stupid. This is so demeaning and cruel, and I cant see who this reaches in positive ways. From the president is truly unbelievable
November 30, 2025 at 2:31 AM
I have friends who have children with neurodevelopmental challenges, or come from various cultures with particular dress codes. This sickens me, in addition to piggy and stupid. This is so demeaning and cruel, and I cant see who this reaches in positive ways. From the president is truly unbelievable
Reposted by Prasad Jallepalli, MD, PhD
The chapter where he blames civilian PhDs teaching in military institutions as a key vector for infecting the military with Marxism was a real morale boost for me
November 30, 2025 at 2:31 AM
The chapter where he blames civilian PhDs teaching in military institutions as a key vector for infecting the military with Marxism was a real morale boost for me
Reposted by Prasad Jallepalli, MD, PhD
What a headline. www.nytimes.com/2025/11/29/n...
The Ex-President Whom Trump Plans to Pardon Flooded America With Cocaine
www.nytimes.com
November 30, 2025 at 2:04 AM
What a headline. www.nytimes.com/2025/11/29/n...
Reposted by Prasad Jallepalli, MD, PhD
Yes, 5 min warning of a nuke and I can do a lot to make myself and my house safer (turn off power and gas, aluminum blinds down, hunker down in basement with fire extinguisher and clear exit path, etc. And one nuke won't reduce society to better off dead CHUDdom
10/n
likelihood of survival & lower-injury especially with only one weapon involved can be greatly increased for people outside the high-probability-kill area by shelter in place (get under desks, stay away from windows, get off streets, etc) efforts.
Yes tell people if a nuke is in-bound.
likelihood of survival & lower-injury especially with only one weapon involved can be greatly increased for people outside the high-probability-kill area by shelter in place (get under desks, stay away from windows, get off streets, etc) efforts.
Yes tell people if a nuke is in-bound.
November 30, 2025 at 2:06 AM
Yes, 5 min warning of a nuke and I can do a lot to make myself and my house safer (turn off power and gas, aluminum blinds down, hunker down in basement with fire extinguisher and clear exit path, etc. And one nuke won't reduce society to better off dead CHUDdom
Reposted by Prasad Jallepalli, MD, PhD
"Never spread the lie in the headline" should be a hard rule of 21st century journalism.
Research shows that repeating lies helps to spread them, and people read headlines more than they read stories.
Research shows that repeating lies helps to spread them, and people read headlines more than they read stories.
News media has to do better with headlines that present false and unverified public health claims.
November 30, 2025 at 1:10 AM
"Never spread the lie in the headline" should be a hard rule of 21st century journalism.
Research shows that repeating lies helps to spread them, and people read headlines more than they read stories.
Research shows that repeating lies helps to spread them, and people read headlines more than they read stories.
Reposted by Prasad Jallepalli, MD, PhD
Now Senate Armed Services Committee and House Armed Services Committee - vow "vigorous oversight" and "full accounting" of Secretary Hegseth's alleged "kill them all" order and double-strike operation.
Rare joint statements by GOP Chairman and Ranking Member on both committees
Rare joint statements by GOP Chairman and Ranking Member on both committees
November 30, 2025 at 2:15 AM
Now Senate Armed Services Committee and House Armed Services Committee - vow "vigorous oversight" and "full accounting" of Secretary Hegseth's alleged "kill them all" order and double-strike operation.
Rare joint statements by GOP Chairman and Ranking Member on both committees
Rare joint statements by GOP Chairman and Ranking Member on both committees
a de facto anti-miscegenation policy
November 30, 2025 at 1:17 AM
a de facto anti-miscegenation policy
Reposted by Prasad Jallepalli, MD, PhD
i do not regret to inform you that we are going to win
Dimon on why JPMorgan Chase is not funding WH Ballroom:
We have an issue, which is anything we do, since we do a lot of contracts with governments here and around the world, we have to be very careful how anything is perceived, and also how the next DOJ is going to deal with it.
We have an issue, which is anything we do, since we do a lot of contracts with governments here and around the world, we have to be very careful how anything is perceived, and also how the next DOJ is going to deal with it.
November 30, 2025 at 12:51 AM
i do not regret to inform you that we are going to win
Reposted by Prasad Jallepalli, MD, PhD
Props to the protestors who the New York Times credits for foiling ICE’s intended raid in Chinatown earlier today.
So many people are showing they know what it means to be New Yorkers!
www.nytimes.com/2025/11/29/n...
So many people are showing they know what it means to be New Yorkers!
www.nytimes.com/2025/11/29/n...
Several Arrested as Protesters Block Federal Agents in Manhattan Garage
www.nytimes.com
November 29, 2025 at 11:32 PM
Props to the protestors who the New York Times credits for foiling ICE’s intended raid in Chinatown earlier today.
So many people are showing they know what it means to be New Yorkers!
www.nytimes.com/2025/11/29/n...
So many people are showing they know what it means to be New Yorkers!
www.nytimes.com/2025/11/29/n...
Reposted by Prasad Jallepalli, MD, PhD
If these were my parents, I wouldn't be recording a podcast with them.
In fact, I'd never speak to them again.
What horrible, culty, hateful, cruel, sickening people.
Imagine telling your child you'd still support Trump if he ordered the military to gun you down.
In fact, I'd never speak to them again.
What horrible, culty, hateful, cruel, sickening people.
Imagine telling your child you'd still support Trump if he ordered the military to gun you down.
On “The Necessary Conversation” podcast, Chad’s Trump supporter parents tell him the military should follow Trump’s illegal orders and kill everyone in LA if Trump commanded it — even with him and his sister in the city😳
November 30, 2025 at 12:18 AM
If these were my parents, I wouldn't be recording a podcast with them.
In fact, I'd never speak to them again.
What horrible, culty, hateful, cruel, sickening people.
Imagine telling your child you'd still support Trump if he ordered the military to gun you down.
In fact, I'd never speak to them again.
What horrible, culty, hateful, cruel, sickening people.
Imagine telling your child you'd still support Trump if he ordered the military to gun you down.
Reposted by Prasad Jallepalli, MD, PhD
There are news reports that Hegseth personally issued orders to “kill everybody” on a boat accused of drug trafficking
A group of former JAGs explains that "both the giving and the execution of these orders, if true, to constitute war crimes, murder, or both."
www.justsecurity.org/wp-content/u...
A group of former JAGs explains that "both the giving and the execution of these orders, if true, to constitute war crimes, murder, or both."
www.justsecurity.org/wp-content/u...
November 29, 2025 at 10:34 PM
There are news reports that Hegseth personally issued orders to “kill everybody” on a boat accused of drug trafficking
A group of former JAGs explains that "both the giving and the execution of these orders, if true, to constitute war crimes, murder, or both."
www.justsecurity.org/wp-content/u...
A group of former JAGs explains that "both the giving and the execution of these orders, if true, to constitute war crimes, murder, or both."
www.justsecurity.org/wp-content/u...
Reposted by Prasad Jallepalli, MD, PhD
Prasad and his ghoulish Great Barrington declaration colleagues are quite literally insane. We should make vaccines more available, not less. Everyone should get all vaccines for which they're eligible.
Here's Prasad's full email, if you'd like to read it for yourself: www.washingtonpost.com/documents/30...
And I jotted down a few thoughts on my substack, including how the strategy of "asking more evidence" — which on the surface, sure, everyone wants more data — can lead to red tape.
And I jotted down a few thoughts on my substack, including how the strategy of "asking more evidence" — which on the surface, sure, everyone wants more data — can lead to red tape.
FDA's big change to how vaccines will get approved
We obtained an internal email laying out the planned shift in strategy.
dandiamond.substack.com
November 29, 2025 at 6:11 PM
Prasad and his ghoulish Great Barrington declaration colleagues are quite literally insane. We should make vaccines more available, not less. Everyone should get all vaccines for which they're eligible.
Reposted by Prasad Jallepalli, MD, PhD
Thing is, we DID hear about it at his confirmation hearing.
Every single senator who voted to confirm Hegseth knew he held these views about the laws of war.
They voted to confirm him anyway.
Every single senator who voted to confirm Hegseth knew he held these views about the laws of war.
They voted to confirm him anyway.
Everyone should read this terrifying thread about Hegseth’s published views wrt war crimes. It’s pretty fucking radical …. We needed to hear about this in his confirmation hearing.
A chapter in Hegseth’s book is literally titled “More Lethality, Less Lawyers.”
It’s almost as if there were signs!
It’s almost as if there were signs!
November 29, 2025 at 6:01 PM
Thing is, we DID hear about it at his confirmation hearing.
Every single senator who voted to confirm Hegseth knew he held these views about the laws of war.
They voted to confirm him anyway.
Every single senator who voted to confirm Hegseth knew he held these views about the laws of war.
They voted to confirm him anyway.
Reposted by Prasad Jallepalli, MD, PhD
Breaking news: Tom Stoppard, the Czech-born British playwright whose intellectually daring and verbally dazzling works became some of the most acclaimed and frequently staged of the past half-century, has died at 88.
Tom Stoppard, playwright of electric verve, dies at 88
His intellectually challenging and verbally dazzling works, including “Arcadia” and “Rosencrantz and Guildenstern Are Dead,” were among the most acclaimed and oft-performed plays of the last half-cen...
wapo.st
November 29, 2025 at 5:48 PM
Breaking news: Tom Stoppard, the Czech-born British playwright whose intellectually daring and verbally dazzling works became some of the most acclaimed and frequently staged of the past half-century, has died at 88.