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Joel S. @joelhs.bsky.social · 29m

“There is a bleeding wound as long as there are mothers waiting to find the graves of their sons, wives waiting to find the graves of their husbands, and children waiting to find the graves of their fathers.” www.reuters.com/world/middle...

Exclusive: Assad government secretly moved mass grave to cover up killings, Reuters investigation finds

From 2019 to 2021, Syria’s authoritarian government carried out a secret operation to move tens of thousands of bodies from the exposed Qutayfah mass grave to a hidden site in the desert east of Damascus. The goal of the clandestine reburial was to hide evidence of atrocities as Bashar Assad tried to regain international standing

www.reuters.com

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grumpyoldscientist.bsky.social @grumpyoldscientist.bsky.social · 16m

Yes, Vinay can run all the things. ( except for being off site most of the time, and not actually liking “ management “. ) But since scientific evidence is no longer required for FDA decisions, it’s a much more manageable bunch of jobs.

grumpyoldscientist.bsky.social @grumpyoldscientist.bsky.social · 33m

Anyone who can publish the piece about starving children in Gaza having preexisting conditions and talk about her personal “trauma” deserves to be ostracized.

grumpyoldscientist.bsky.social @grumpyoldscientist.bsky.social · 42m

I don’t know, seems clear to me.

grumpyoldscientist.bsky.social @grumpyoldscientist.bsky.social · 3h

I worked in Fed gov for 30 years. It’s hard to chart a course when you are moving forward rapidly without a map. I grant some grace. But you are right, Biden should have figured this out. Dems need to be a party that supports what they purportedly stand for. But beating up Biden achieves nothing.

grumpyoldscientist.bsky.social @grumpyoldscientist.bsky.social · 3h

I guess my point is if you don’t support the dems because they supported something became reprehensible, who do you support? FDR purposely hid the holocaust because he thought his job was to focus solely on ending the war. You can support no one, but that is voting in its own way.

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grumpyoldscientist.bsky.social @grumpyoldscientist.bsky.social · 3h

And you would be correct.

grumpyoldscientist.bsky.social @grumpyoldscientist.bsky.social · 4h

Political parties ( and governments) do morally questionable things all the time. There are probably some puzzle pieces here we can’t see. Dems need to figure out who their constituencies really are, or should be, and stop catering to folks who are only “just” not Republicans.

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Reposted

Holly Anderson 🍇 @hollyanderson.bsky.social · 7h

you fucked around and now the Episcopalians are doing memes. are you happy now. are you

Screenshot of a Facebook post featuring three of the Portland protesters wearing inflatable frog costumes with the following text:

Episcopalians on Facebook
Elizabeth Rose Elrod • 22h •
Exodus 8:2-6
"But if you refuse to let them go, I will plague your whole country with frogs...
The frogs shall come up on you and on your people and on all your officials."

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grumpyoldscientist.bsky.social @grumpyoldscientist.bsky.social · 5h

Particularly when the Republicans get most everything wrong all the time. All this Monday quarterbacking is not useful.

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grumpyoldscientist.bsky.social @grumpyoldscientist.bsky.social · 5h

They should have done this decades ago. Instead they embraced free marketing, and see where that got them.

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grumpyoldscientist.bsky.social @grumpyoldscientist.bsky.social · 6h

No, you are reality based. But a lot of reasonable Israelis are really grateful to Trump, an indicator of their national stress, and in the US… well you know what that is about.

grumpyoldscientist.bsky.social @grumpyoldscientist.bsky.social · 7h

But … money…

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grumpyoldscientist.bsky.social @grumpyoldscientist.bsky.social · 7h

Gee, marketing a class III without reg approval. In a normal world, they would send folks in to shut them down. Be interesting to see if FDA puts teeth in this.

grumpyoldscientist.bsky.social @grumpyoldscientist.bsky.social · 8h

Well, to be honest, the blue hair set will be there too. Pissed off retired Feds, for example.

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grumpyoldscientist.bsky.social @grumpyoldscientist.bsky.social · 9h

Almost like they are not … rational, huh?

grumpyoldscientist.bsky.social @grumpyoldscientist.bsky.social · 1d

And biggest joy: traumatizing federal workers. Second biggest: reducing the administrative state to ashes without a backup plan.

grumpyoldscientist.bsky.social @grumpyoldscientist.bsky.social · 1d

Also, and more disturbingly, this is an expansion of a drug label without adhering to normal process. Which is to have ACTUAL CLINICAL DATA to support the expansion. Not just a literature search.

grumpyoldscientist.bsky.social @grumpyoldscientist.bsky.social · 1d

This is likely true. But Frye’s contribution to this is highly questionable. And while the FDA communicated the accurate info to physicians on what patient might be improved by this drug, Makary implied in a public announcement that this was a big breakthrough for all autism.

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grumpyoldscientist.bsky.social @grumpyoldscientist.bsky.social · 1d

When the FDA stops your trial by issuing a hold based on 21 CFR 312.42 “unreasonable and significant risk of illness or injury to human subjects,” …

This is some of the background that purports to support the use of Leucovorin as a cure-all for autism.

LizW @cave-malum.bsky.social · 1d

They're getting there.
And follow the $: www.medpagetoday.com/pediatrics/a...
Likely more to come.

Exclusive: Meet Richard Frye, who studies leucovorin for autism

Frye has led two placebo-controlled trials of the folate supplement in autistic people; the first was suspended by regulators, and the other has yet to be published.

www.thetransmitter.org

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grumpyoldscientist.bsky.social @grumpyoldscientist.bsky.social · 1d

@cave-malum.bsky.social , maybe someone will dig into the sorry trail of clinical data supporting this?

This travesty should not be allowed to go away, the process, the outcome, the whole disturbing story.

www.statnews.com/2025/10/14/f...