@grumpyoldscientist.bsky.social
Recovering federal regulator, molecular biologist, serious dog person
Well, that will drive off another tranch of highly qualified reviewers. The cadre of researcher reviewers are most of the longest serving staff at CBER.
In an email to staff filled with unsupported accusations about the quality of the center’s research, CBER Director Vinay Prasad said no resources or time should be spent on ongoing projects started before he joined the FDA until discussed with him. #healthpolicy
CBER Poised for Research Shakeup As Prasad Makes Unproven Claims About ‘Polluted Science’
In an email to staff filled with unsupported accusations about the quality of the center’s research, CBER Director Vinay Prasad said no resources or time should be spent on ongoing projects started be...
insights.citeline.com
November 25, 2025 at 12:38 AM
Well, that will drive off another tranch of highly qualified reviewers. The cadre of researcher reviewers are most of the longest serving staff at CBER.
A very effective graphic of where things stand. That’s only 35 years, folks.
if you came of age in the 20th century then this really sits you down about how much the Worlds changed in 21st century. no going back…. @katemac.bsky.social
Germany was 4 times China's GDP in 1990
China is now 4 times Germany's GDP in 2025
www.phenomenalworld.org/analysis/bri...
Germany was 4 times China's GDP in 1990
China is now 4 times Germany's GDP in 2025
www.phenomenalworld.org/analysis/bri...
November 24, 2025 at 9:31 PM
A very effective graphic of where things stand. That’s only 35 years, folks.
Reposted
Fact, and all scientific leaders should say this to his face.
Stop trying to butter up or compromise with Cassidy and Susan Collins. It will not work! Believing it will is a flawed theory of how US politics works in 2025.
Stop trying to butter up or compromise with Cassidy and Susan Collins. It will not work! Believing it will is a flawed theory of how US politics works in 2025.
Bill Cassidy has done infinitely more for the antivaccine movement than he can ever claim he has done to promote vaccination. He is one of the worst antivaxxers to ever live.
With all my heart, fuck this guy.
November 23, 2025 at 6:26 PM
Fact, and all scientific leaders should say this to his face.
Stop trying to butter up or compromise with Cassidy and Susan Collins. It will not work! Believing it will is a flawed theory of how US politics works in 2025.
Stop trying to butter up or compromise with Cassidy and Susan Collins. It will not work! Believing it will is a flawed theory of how US politics works in 2025.
Titillation? He is titillated by overturning established public health knowledge? What is wrong with this guy?
CASSIDY: I know it's titillating, but I think we need to move beyond the titillation
TAPPER: This isn't about titillation. This is about the fact that you are the chairman of the health committee and you voted to confirm somebody that by all accounts is actually making America less healthy
TAPPER: This isn't about titillation. This is about the fact that you are the chairman of the health committee and you voted to confirm somebody that by all accounts is actually making America less healthy
November 23, 2025 at 3:47 PM
Titillation? He is titillated by overturning established public health knowledge? What is wrong with this guy?
Reposted
1) Start the worst European war since 1945 and commit every imaginable war crime
2) Decide how you want to be rewarded for your aggression
3) Leak the list of your desiderata to the US press
4) Wait for the US president to enforce your wish list on your victim.
Russian policy 2025
2) Decide how you want to be rewarded for your aggression
3) Leak the list of your desiderata to the US press
4) Wait for the US president to enforce your wish list on your victim.
Russian policy 2025
November 23, 2025 at 3:30 PM
1) Start the worst European war since 1945 and commit every imaginable war crime
2) Decide how you want to be rewarded for your aggression
3) Leak the list of your desiderata to the US press
4) Wait for the US president to enforce your wish list on your victim.
Russian policy 2025
2) Decide how you want to be rewarded for your aggression
3) Leak the list of your desiderata to the US press
4) Wait for the US president to enforce your wish list on your victim.
Russian policy 2025
Reposted
Get serious, Europeans. You are your only hope.
"EU imports from Russia worth €124 billion have exceeded the amount of aid provided to Ukraine since the start of the full-scale invasion." - stated Sweden’s Foreign Minister Maria Malmer Stenergard.
censor.net/en/news/3586...
censor.net/en/news/3586...
November 23, 2025 at 3:34 PM
Get serious, Europeans. You are your only hope.
Reposted
DOGE did not fail in any way to accomplish its goals.
Its goals were never efficiency or saving money.
Its goals were to destroy as much of government as possible forever, and to steal data for the Space Nazi.
DOGE is fading away like bank robbery gangs fade away after the robberies are done.
Its goals were never efficiency or saving money.
Its goals were to destroy as much of government as possible forever, and to steal data for the Space Nazi.
DOGE is fading away like bank robbery gangs fade away after the robberies are done.
Exclusive: DOGE 'doesn't exist' with eight months left on its charter reut.rs/4abeTdx
Exclusive: DOGE 'doesn't exist' with eight months left on its charter
The Department of Government Efficiency claimed to have slashed tens of billions of dollars in expenditures, but it was impossible for outside financial experts to verify that because the unit did not provide detailed public accounting of its work.
reut.rs
November 23, 2025 at 12:26 PM
DOGE did not fail in any way to accomplish its goals.
Its goals were never efficiency or saving money.
Its goals were to destroy as much of government as possible forever, and to steal data for the Space Nazi.
DOGE is fading away like bank robbery gangs fade away after the robberies are done.
Its goals were never efficiency or saving money.
Its goals were to destroy as much of government as possible forever, and to steal data for the Space Nazi.
DOGE is fading away like bank robbery gangs fade away after the robberies are done.
Some have been breached? Some?
Explore this gift article from The New York Times.
Before casting a crucial vote for the health secretary, Cassidy laid out several specific commitments he had secured, some of which appear to have been breached.
www.nytimes.com/2025/11/21/u...
Explore this gift article from The New York Times.
Before casting a crucial vote for the health secretary, Cassidy laid out several specific commitments he had secured, some of which appear to have been breached.
www.nytimes.com/2025/11/21/u...
Cassidy Got Pledges From Kennedy on Vaccines. They Haven’t Stuck.
www.nytimes.com
November 22, 2025 at 11:29 PM
Some have been breached? Some?
Explore this gift article from The New York Times.
Before casting a crucial vote for the health secretary, Cassidy laid out several specific commitments he had secured, some of which appear to have been breached.
www.nytimes.com/2025/11/21/u...
Explore this gift article from The New York Times.
Before casting a crucial vote for the health secretary, Cassidy laid out several specific commitments he had secured, some of which appear to have been breached.
www.nytimes.com/2025/11/21/u...
Reposted
This is not a peace plan. It is a proposal that weakens Ukraine and divides America from Europe, preparing the way for a larger war in the future. In the meantime, it benefits unnamed Russian and American investors, at the expense of everyone else.
www.theatlantic.com/ideas/2025/1...
www.theatlantic.com/ideas/2025/1...
Trump Has a Recipe for War and Corruption, Not Peace
Who would benefit from the White House’s 28-point proposal for Ukraine?
www.theatlantic.com
November 22, 2025 at 11:11 AM
This is not a peace plan. It is a proposal that weakens Ukraine and divides America from Europe, preparing the way for a larger war in the future. In the meantime, it benefits unnamed Russian and American investors, at the expense of everyone else.
www.theatlantic.com/ideas/2025/1...
www.theatlantic.com/ideas/2025/1...
The Substack is long, but worth reading. Lots of interesting insights. All the circular financing. The Bitcoin behind everything. “Vibe Revenue “. AI discovering irregularities faster than humans for an AI company. Ah, the irony.
Remember: if it sounds to good to be true, it is not true.
Remember: if it sounds to good to be true, it is not true.
NVIDIA earnings were a mirage. The market figured it out surprisingly fast. NVIDIA bump evaporated.
I don’t know how this information can enter the system without exploding the bubble.
But sometimes bezzles visible for months before crash.
Waiting for the feds?
open.substack.com/pub/shanakaa...
I don’t know how this information can enter the system without exploding the bubble.
But sometimes bezzles visible for months before crash.
Waiting for the feds?
open.substack.com/pub/shanakaa...
November 22, 2025 at 1:45 PM
The Substack is long, but worth reading. Lots of interesting insights. All the circular financing. The Bitcoin behind everything. “Vibe Revenue “. AI discovering irregularities faster than humans for an AI company. Ah, the irony.
Remember: if it sounds to good to be true, it is not true.
Remember: if it sounds to good to be true, it is not true.
From NYTs article:Epstein and professors:
The evolutionary biologist Robert Trivers defended Mr. Epstein, saying girls mature sooner than they used to. “By the time they’re 14 or 15, they’re like grown women were 60 years ago, so I don’t see these acts as so heinous”.
Really fast evolution, that.
The evolutionary biologist Robert Trivers defended Mr. Epstein, saying girls mature sooner than they used to. “By the time they’re 14 or 15, they’re like grown women were 60 years ago, so I don’t see these acts as so heinous”.
Really fast evolution, that.
November 22, 2025 at 2:29 AM
From NYTs article:Epstein and professors:
The evolutionary biologist Robert Trivers defended Mr. Epstein, saying girls mature sooner than they used to. “By the time they’re 14 or 15, they’re like grown women were 60 years ago, so I don’t see these acts as so heinous”.
Really fast evolution, that.
The evolutionary biologist Robert Trivers defended Mr. Epstein, saying girls mature sooner than they used to. “By the time they’re 14 or 15, they’re like grown women were 60 years ago, so I don’t see these acts as so heinous”.
Really fast evolution, that.
Hazardous waste dumps and fossil fuel ports. Sounds good. Of course those are always located among populations no one cares about.
thehill.com/policy/energ...
thehill.com/policy/energ...
thehill.com
November 21, 2025 at 6:23 PM
Hazardous waste dumps and fossil fuel ports. Sounds good. Of course those are always located among populations no one cares about.
thehill.com/policy/energ...
thehill.com/policy/energ...
Watching houses collapse into the sea is sort of interesting, but: The east coast is sinking, the ocean is rising. Sand bars are not “ land”. The federal flood insurance system just encourages this.
Explore this gift article from The New York Times.
www.nytimes.com/2025/11/19/m...
Explore this gift article from The New York Times.
www.nytimes.com/2025/11/19/m...
Houses Collapsing Into the Sea? It’s Not as Baffling as It Looks.
www.nytimes.com
November 21, 2025 at 4:31 PM
Watching houses collapse into the sea is sort of interesting, but: The east coast is sinking, the ocean is rising. Sand bars are not “ land”. The federal flood insurance system just encourages this.
Explore this gift article from The New York Times.
www.nytimes.com/2025/11/19/m...
Explore this gift article from The New York Times.
www.nytimes.com/2025/11/19/m...
Shame and embarrassment have not totally left the room? That’s news to me, but welcome nonetheless.
The Coast Guard reversed its 'swastikas aren't all that bad' policy just hours after the Washpost broke the story.
It's both surprising, and good, to see that one government agency these days is capable of being embarrassed, and changing course quickly.
www.washingtonpost.com/national-sec...
It's both surprising, and good, to see that one government agency these days is capable of being embarrassed, and changing course quickly.
www.washingtonpost.com/national-sec...
In reversal, Coast Guard again classifies swastikas, nooses as hate symbols
The new order came hours after The Post reported the service would instead classify such symbols as “potentially divisive” under guidelines set for release next month.
www.washingtonpost.com
November 21, 2025 at 3:43 PM
Shame and embarrassment have not totally left the room? That’s news to me, but welcome nonetheless.
Land subsidence due to aquifer depletion, lack of water. Going to happen lots of places. If there are future historians, they will identify climate change as the major population and political disruption of the 21st century.
www.iranintl.com/en/202511209...
www.iranintl.com/en/202511209...
Iran president says capital move now a necessity as water crisis deepens
Iran’s capital must be moved because the country “no longer has a choice,” President Masoud Pezeshkian said on Thursday in remarks carried by state media, warning that severe ecological strain has mad...
www.iranintl.com
November 21, 2025 at 2:52 PM
Land subsidence due to aquifer depletion, lack of water. Going to happen lots of places. If there are future historians, they will identify climate change as the major population and political disruption of the 21st century.
www.iranintl.com/en/202511209...
www.iranintl.com/en/202511209...
Ah, irrational exuberance, now there is an expression we remember.
November 21, 2025 at 1:38 PM
Ah, irrational exuberance, now there is an expression we remember.
Starting an unnecessary war that may have killed as many as a million Iraqis and ~ 5K Americans. Normalizing torture. How soon we forget.
November 20, 2025 at 11:14 PM
Starting an unnecessary war that may have killed as many as a million Iraqis and ~ 5K Americans. Normalizing torture. How soon we forget.
For those of you watching Trump/Rufo education, we have the test case: DeSantis education. Overpaid president, most expensive per student costs, down 60 points in rankings. But they fixed up the buildings. If they were neglected, it’s because the state provided minimal $ until now.
wapo.st/4pjbqOn
wapo.st/4pjbqOn
DeSantis’s makeover of ‘left-wing’ Florida college has been costly
Gov. Ron DeSantis’s makeover of the public honors college has been thorough — and costly, a new report shows.
wapo.st
November 20, 2025 at 7:07 PM
For those of you watching Trump/Rufo education, we have the test case: DeSantis education. Overpaid president, most expensive per student costs, down 60 points in rankings. But they fixed up the buildings. If they were neglected, it’s because the state provided minimal $ until now.
wapo.st/4pjbqOn
wapo.st/4pjbqOn
Add “driving suspiciously” to all the other driving related dangers.
November 20, 2025 at 6:05 PM
Add “driving suspiciously” to all the other driving related dangers.
Reposted
A lot of people criticized Black Mirror for being too didactic in its critiques of the dangers of technology, but compared to reality it was very subtle and nuanced.
www.cnn.com/2025/11/19/t...
www.cnn.com/2025/11/19/t...
Sales of AI-enabled teddy bear suspended after it gave advice on BDSM sex and where to find knives | CNN Business
Sales of an artificial intelligence-enabled plush toy have been suspended after it was found that it engaged in conversation around sexually explicit topics and offered potentially dangerous advice.
www.cnn.com
November 20, 2025 at 12:27 PM
A lot of people criticized Black Mirror for being too didactic in its critiques of the dangers of technology, but compared to reality it was very subtle and nuanced.
www.cnn.com/2025/11/19/t...
www.cnn.com/2025/11/19/t...
MAHA in action. I guess if you have a “good” immune system, botulinum toxin is no threat.
ByHeart, the baby formula maker at center of a botulism outbreak investgiation, donated products to homeless, at-risk families. It's unclear what's being done to alert them.
Recalled baby formula linked to botulism outbreak was donated to struggling families
ByHeart, the baby formula maker at center of a botulism outbreak investgiation, donated products to homeless, at-risk families. It's unclear what's being done to alert them.
bit.ly
November 20, 2025 at 3:51 AM
MAHA in action. I guess if you have a “good” immune system, botulinum toxin is no threat.
Reposted
This absurd oversensitivity about professors having sex with minors procured for them by sex criminals shows that campus cancel culture is out of control.
by Alan Dershowitz and Larry Summers
by Alan Dershowitz and Larry Summers
November 20, 2025 at 1:30 AM
This absurd oversensitivity about professors having sex with minors procured for them by sex criminals shows that campus cancel culture is out of control.
by Alan Dershowitz and Larry Summers
by Alan Dershowitz and Larry Summers
Note that training Chinese may make you ineligible for NIH grants, yet:
China-sourced molecules accounted for 37% of U.S. drugmakers’ pipelines
Despite new FDA initiatives, there’s not enough financial incentive for U.S. firms to shift manufacturing domestically
www.statnews.com/2025/11/17/w...
China-sourced molecules accounted for 37% of U.S. drugmakers’ pipelines
Despite new FDA initiatives, there’s not enough financial incentive for U.S. firms to shift manufacturing domestically
www.statnews.com/2025/11/17/w...
China’s WuXi AppTec, after evading threat of U.S. restrictions, comes out ahead
WuXi AppTec, the Chinese pharma giant with extensive ties with U.S. companies, appears to be thriving now that the threat of U.S. restrictions has dissipated.
www.statnews.com
November 17, 2025 at 1:35 PM
Note that training Chinese may make you ineligible for NIH grants, yet:
China-sourced molecules accounted for 37% of U.S. drugmakers’ pipelines
Despite new FDA initiatives, there’s not enough financial incentive for U.S. firms to shift manufacturing domestically
www.statnews.com/2025/11/17/w...
China-sourced molecules accounted for 37% of U.S. drugmakers’ pipelines
Despite new FDA initiatives, there’s not enough financial incentive for U.S. firms to shift manufacturing domestically
www.statnews.com/2025/11/17/w...