JB Manent
@jbmanent.bsky.social
Developmental neurobiologist studying cortical malformations (grey matter heterotopia) and #epilepsy at INMED, INSERM in Marseille, France
https://orcid.org/0000-0002-2436-8593
https://orcid.org/0000-0002-2436-8593
Pinned
JB Manent
@jbmanent.bsky.social
· Aug 1
Interested in cortical malformations 🧠 and #epilepsy?
We will soon have 2 open positions:
- early career postdoc with experience in slice & in vivo electrophysiology
- research engineer with experience in bioinformatics and data analysis
Please get in touch (DM) if interested.
Please repost!
We will soon have 2 open positions:
- early career postdoc with experience in slice & in vivo electrophysiology
- research engineer with experience in bioinformatics and data analysis
Please get in touch (DM) if interested.
Please repost!
Reposted by JB Manent
Re-upping this - Neuropeeps! We have a TT Job in my wonderful department at Brandeis! First consideration to applications received by Dec 15 (but why wait?)
www.nature.com/naturecareer...
www.nature.com/naturecareer...
Assistant Professor in Biology and Neuroscience Program - Waltham, Massachusetts (US) job with Brandeis University | 12848464
The Department of Biology and the Program in Neuroscience at Brandeis University invite applications for a tenure-track Assistant Professor positio...
www.nature.com
November 20, 2025 at 3:03 PM
Re-upping this - Neuropeeps! We have a TT Job in my wonderful department at Brandeis! First consideration to applications received by Dec 15 (but why wait?)
www.nature.com/naturecareer...
www.nature.com/naturecareer...
Reposted by JB Manent
Excited to share that our study has been accepted in Progress in Neurobiology!🎉
We show that cocaine activates the JAK-STAT3 pathway in astrocytes, and that reducing this reactivity mitigates cocaine-induced hyperlocomotion.
www.sciencedirect.com/science/arti...
#astrocyte #cocaine #glia #brain
We show that cocaine activates the JAK-STAT3 pathway in astrocytes, and that reducing this reactivity mitigates cocaine-induced hyperlocomotion.
www.sciencedirect.com/science/arti...
#astrocyte #cocaine #glia #brain
Inhibiting the JAK-STAT3 pathway in nucleus accumbens astrocytes alleviates cocaine-induced motor hyperactivity
Cocaine use disorder is a significant global health issue, and despite its widespread impact, effective treatments are lacking. While research has lar…
www.sciencedirect.com
November 19, 2025 at 10:21 AM
Excited to share that our study has been accepted in Progress in Neurobiology!🎉
We show that cocaine activates the JAK-STAT3 pathway in astrocytes, and that reducing this reactivity mitigates cocaine-induced hyperlocomotion.
www.sciencedirect.com/science/arti...
#astrocyte #cocaine #glia #brain
We show that cocaine activates the JAK-STAT3 pathway in astrocytes, and that reducing this reactivity mitigates cocaine-induced hyperlocomotion.
www.sciencedirect.com/science/arti...
#astrocyte #cocaine #glia #brain
Reposted by JB Manent
Come work with us! I am available if you need more information. @ibensens.bsky.social
@psl-univ.bsky.social
#iGlur
@psl-univ.bsky.social
#iGlur
The Paoletti team is hiring a Postdoc position - IBENS Paris !
#neuroscience
#electrophysiology
#imaging
#neuroscience
#electrophysiology
#imaging
October 31, 2025 at 9:27 AM
Come work with us! I am available if you need more information. @ibensens.bsky.social
@psl-univ.bsky.social
#iGlur
@psl-univ.bsky.social
#iGlur
Reposted by JB Manent
The Paoletti team is hiring a Postdoc position - IBENS Paris !
#neuroscience
#electrophysiology
#imaging
#neuroscience
#electrophysiology
#imaging
October 31, 2025 at 9:10 AM
The Paoletti team is hiring a Postdoc position - IBENS Paris !
#neuroscience
#electrophysiology
#imaging
#neuroscience
#electrophysiology
#imaging
Reposted by JB Manent
🧠 Check out our new study!
Cécile Bridlance et al. reveal how distinct, local, and cell-type–specific sources of CSF-1 orchestrate microglial colonization during early brain development.
🙏🙏🙏 A big thank you to everyone involved!
Cécile Bridlance et al. reveal how distinct, local, and cell-type–specific sources of CSF-1 orchestrate microglial colonization during early brain development.
🙏🙏🙏 A big thank you to everyone involved!
Microglial colonization of the developing mouse brain is controlled by both microglial and neural CSF-1
Sonia Garel, @morganethion.bsky.social and collaborators
www.embopress.org/doi/full/10....
Sonia Garel, @morganethion.bsky.social and collaborators
www.embopress.org/doi/full/10....
November 20, 2025 at 2:35 PM
🧠 Check out our new study!
Cécile Bridlance et al. reveal how distinct, local, and cell-type–specific sources of CSF-1 orchestrate microglial colonization during early brain development.
🙏🙏🙏 A big thank you to everyone involved!
Cécile Bridlance et al. reveal how distinct, local, and cell-type–specific sources of CSF-1 orchestrate microglial colonization during early brain development.
🙏🙏🙏 A big thank you to everyone involved!
Reposted by JB Manent
Comment tu parles ?
Le langage, les langues de Marseille, les mots et les accents, on en parle ce soir à l’Espace Julien : un débat et des échanges avec Prïncia Car (19h) suivis d’un concert de Temenik Electric (un nom idéal pour le… Cours Ju 😅)
Vous venez ?
espace-julien.com/agenda/nouve...
Le langage, les langues de Marseille, les mots et les accents, on en parle ce soir à l’Espace Julien : un débat et des échanges avec Prïncia Car (19h) suivis d’un concert de Temenik Electric (un nom idéal pour le… Cours Ju 😅)
Vous venez ?
espace-julien.com/agenda/nouve...
November 20, 2025 at 6:30 AM
Comment tu parles ?
Le langage, les langues de Marseille, les mots et les accents, on en parle ce soir à l’Espace Julien : un débat et des échanges avec Prïncia Car (19h) suivis d’un concert de Temenik Electric (un nom idéal pour le… Cours Ju 😅)
Vous venez ?
espace-julien.com/agenda/nouve...
Le langage, les langues de Marseille, les mots et les accents, on en parle ce soir à l’Espace Julien : un débat et des échanges avec Prïncia Car (19h) suivis d’un concert de Temenik Electric (un nom idéal pour le… Cours Ju 😅)
Vous venez ?
espace-julien.com/agenda/nouve...
Reposted by JB Manent
I am very excited to be organizing a session for postdocs (with focus on those in the job market). Be on the lookout for info and registration! 🐟🧪
November 19, 2025 at 7:12 PM
I am very excited to be organizing a session for postdocs (with focus on those in the job market). Be on the lookout for info and registration! 🐟🧪
Reposted by JB Manent
Interested in doing a PhD on how #psychedelics (or other psychoactive substances) impact psychological or social processes @durhampsych.bsky.social ?
Have a look at the NINE DTP scheme, now open. DM me if interested.
Have a look at the NINE DTP scheme, now open. DM me if interested.
November 19, 2025 at 9:37 PM
Interested in doing a PhD on how #psychedelics (or other psychoactive substances) impact psychological or social processes @durhampsych.bsky.social ?
Have a look at the NINE DTP scheme, now open. DM me if interested.
Have a look at the NINE DTP scheme, now open. DM me if interested.
Reposted by JB Manent
The field is buzzing about work on brain-computer interfaces for speech, the mechanism of psychedelics, a broader definition of hippocampal representations and more.
www.thetransmitter.org/community/th...
#neuroskyence #StateOfNeuroscience
www.thetransmitter.org/community/th...
#neuroskyence #StateOfNeuroscience
The buzziest neuroscience papers of 2023, 2024
The field took note of work on brain-computer interfaces for speech, the mechanism of psychedelics, defining hippocampal representations, and more.
www.thetransmitter.org
November 19, 2025 at 5:15 PM
The field is buzzing about work on brain-computer interfaces for speech, the mechanism of psychedelics, a broader definition of hippocampal representations and more.
www.thetransmitter.org/community/th...
#neuroskyence #StateOfNeuroscience
www.thetransmitter.org/community/th...
#neuroskyence #StateOfNeuroscience
Reposted by JB Manent
Excited to announce that our latest paper is now out: www.cell.com/neuron/fullt...
Here we uncover a simple cortical code for loudness and leverage it reverse sound hypersensitivity disorders in mice.
#neuroskyence
Here we uncover a simple cortical code for loudness and leverage it reverse sound hypersensitivity disorders in mice.
#neuroskyence
Cortical PV interneurons regulate loudness perception and sustainably reverse loudness hypersensitivity
Noise damages the cochlea, triggering maladaptive plasticity in the auditory cortex
(ACtx) that makes moderate-intensity sounds seem uncomfortably loud. Clayton, Awwad,
McGill, et al. show that brief ...
www.cell.com
November 19, 2025 at 10:31 PM
Excited to announce that our latest paper is now out: www.cell.com/neuron/fullt...
Here we uncover a simple cortical code for loudness and leverage it reverse sound hypersensitivity disorders in mice.
#neuroskyence
Here we uncover a simple cortical code for loudness and leverage it reverse sound hypersensitivity disorders in mice.
#neuroskyence
Will open soon! 🧠⚡🧪🔬
Interested in cortical malformations 🧠 and #epilepsy?
We will soon have 2 open positions:
- early career postdoc with experience in slice & in vivo electrophysiology
- research engineer with experience in bioinformatics and data analysis
Please get in touch (DM) if interested.
Please repost!
We will soon have 2 open positions:
- early career postdoc with experience in slice & in vivo electrophysiology
- research engineer with experience in bioinformatics and data analysis
Please get in touch (DM) if interested.
Please repost!
November 19, 2025 at 1:49 PM
Will open soon! 🧠⚡🧪🔬
Reposted by JB Manent
If you'd like to celebrate the biology of viruses - or the fight against viral diseases - this winter, try out our free and updated #VirusSnowflake designs.
Please share, and if you have any photos of Virus Snowflakes in your area it would be lovely to see them!
cvr-engagement.co.uk/virus-snowfl...
Please share, and if you have any photos of Virus Snowflakes in your area it would be lovely to see them!
cvr-engagement.co.uk/virus-snowfl...
November 17, 2025 at 5:39 PM
If you'd like to celebrate the biology of viruses - or the fight against viral diseases - this winter, try out our free and updated #VirusSnowflake designs.
Please share, and if you have any photos of Virus Snowflakes in your area it would be lovely to see them!
cvr-engagement.co.uk/virus-snowfl...
Please share, and if you have any photos of Virus Snowflakes in your area it would be lovely to see them!
cvr-engagement.co.uk/virus-snowfl...
Reposted by JB Manent
New preprint on bioRvix! We show how cortical sensory-modality identity is instructed by a combinatorial cell-adhesion and activity codes, using #snRNAseq #spatialtranscriptomics #functional imaging. Congrats to everyone on this work! @guillelbendito.bsky.social @neuroalc.bsky.social
Combinatorial Cell-Adhesion and Activity Codes Instruct Cortical Modality Identity
The emergence of functional sensory modalities requires precise cortical arealization and thalamocortical connectivity. While early morphogen gradients broadly initiate cortical patterning, how sensor...
www.biorxiv.org
November 18, 2025 at 7:26 AM
New preprint on bioRvix! We show how cortical sensory-modality identity is instructed by a combinatorial cell-adhesion and activity codes, using #snRNAseq #spatialtranscriptomics #functional imaging. Congrats to everyone on this work! @guillelbendito.bsky.social @neuroalc.bsky.social
Reposted by JB Manent
Our lab digs into how serotonin tunes prediction errors and eye movements — with custom tools and curious mice.We got 2 posters at #SfN2025, Tue AM (C5) and Wed PM (R16).
Recruiting PhD students & postdocs in sunny Marseille.
Come chat about neuromodulators, tinkering, or free will and intuition.
Recruiting PhD students & postdocs in sunny Marseille.
Come chat about neuromodulators, tinkering, or free will and intuition.
November 18, 2025 at 1:16 AM
Our lab digs into how serotonin tunes prediction errors and eye movements — with custom tools and curious mice.We got 2 posters at #SfN2025, Tue AM (C5) and Wed PM (R16).
Recruiting PhD students & postdocs in sunny Marseille.
Come chat about neuromodulators, tinkering, or free will and intuition.
Recruiting PhD students & postdocs in sunny Marseille.
Come chat about neuromodulators, tinkering, or free will and intuition.
Reposted by JB Manent
L’AP-HM a célébré le 13/11/2025 le 4 000ᵉ patient de L’APPART, dispositif de transition entre pédiatrie et médecine adulte à la Timone. Un modèle d’accompagnement coordonné pour les jeunes atteints de maladies chroniques.
ℹ️ fr.ap-hm.fr/site/lappart #SantéPublique #Transition
ℹ️ fr.ap-hm.fr/site/lappart #SantéPublique #Transition
November 17, 2025 at 9:56 AM
L’AP-HM a célébré le 13/11/2025 le 4 000ᵉ patient de L’APPART, dispositif de transition entre pédiatrie et médecine adulte à la Timone. Un modèle d’accompagnement coordonné pour les jeunes atteints de maladies chroniques.
ℹ️ fr.ap-hm.fr/site/lappart #SantéPublique #Transition
ℹ️ fr.ap-hm.fr/site/lappart #SantéPublique #Transition
Reposted by JB Manent
🦣🧬🦣🤯💥We are pleased to share our new paper about ancient RNA expression profiles from the Woolly Mammoth, now published in Cell @cellpress.bsky.social
www.cell.com/cell/fulltex...
If you want to know more, read the 🧵 below:
www.cell.com/cell/fulltex...
If you want to know more, read the 🧵 below:
November 14, 2025 at 4:08 PM
🦣🧬🦣🤯💥We are pleased to share our new paper about ancient RNA expression profiles from the Woolly Mammoth, now published in Cell @cellpress.bsky.social
www.cell.com/cell/fulltex...
If you want to know more, read the 🧵 below:
www.cell.com/cell/fulltex...
If you want to know more, read the 🧵 below:
Reposted by JB Manent
🧠🔬 Postdoc positions open!
The MAP team at the IINS in beautiful Bordeaux is looking for curious and independent researchers to study how neuronal synapses work, adapt, and change at the molecular and cellular levels.
More about the offers 👉 shorturl.at/4KoxR
More about the team 👉 shorturl.at/lzFmN
The MAP team at the IINS in beautiful Bordeaux is looking for curious and independent researchers to study how neuronal synapses work, adapt, and change at the molecular and cellular levels.
More about the offers 👉 shorturl.at/4KoxR
More about the team 👉 shorturl.at/lzFmN
Mechanisms of Adaptive Processes in brain circuits (MAP) × IINS
Interdisciplinary Institute for Neuroscience
shorturl.at
November 16, 2025 at 6:30 PM
🧠🔬 Postdoc positions open!
The MAP team at the IINS in beautiful Bordeaux is looking for curious and independent researchers to study how neuronal synapses work, adapt, and change at the molecular and cellular levels.
More about the offers 👉 shorturl.at/4KoxR
More about the team 👉 shorturl.at/lzFmN
The MAP team at the IINS in beautiful Bordeaux is looking for curious and independent researchers to study how neuronal synapses work, adapt, and change at the molecular and cellular levels.
More about the offers 👉 shorturl.at/4KoxR
More about the team 👉 shorturl.at/lzFmN
Reposted by JB Manent
November 15, 2025 at 4:39 PM
Reposted by JB Manent
Attending #SfN25? Join us tomorrow (11/17) for our SfN Social to learn more about our available resources and funding opportunities. https://www.simonsfoundation.org/event/simons-foundation-autism-and-neuroscience-social-2025/ #science #neuroscience #autismresearch
Simons Foundation Autism and Neuroscience SfN Social
Simons Foundation Autism and Neuroscience SfN Social on Simons Foundation
www.simonsfoundation.org
November 16, 2025 at 7:21 PM
Attending #SfN25? Join us tomorrow (11/17) for our SfN Social to learn more about our available resources and funding opportunities. https://www.simonsfoundation.org/event/simons-foundation-autism-and-neuroscience-social-2025/ #science #neuroscience #autismresearch
Reposted by JB Manent
My new ImageJ / Fiji toolkit is out 🔥! The goal is to make image handling & visualization easy, with an intuitive interface! Install it on Fiji with the "Image Viewer" update site
#microscopy #ImageJ #FluorescenceFriday #microscopyMonday
imagej.net/plugins/imag...
#microscopy #ImageJ #FluorescenceFriday #microscopyMonday
imagej.net/plugins/imag...
November 4, 2025 at 10:40 PM
My new ImageJ / Fiji toolkit is out 🔥! The goal is to make image handling & visualization easy, with an intuitive interface! Install it on Fiji with the "Image Viewer" update site
#microscopy #ImageJ #FluorescenceFriday #microscopyMonday
imagej.net/plugins/imag...
#microscopy #ImageJ #FluorescenceFriday #microscopyMonday
imagej.net/plugins/imag...
Reposted by JB Manent
🗨️ Just published in Nature Biotechnology: Our CellWhisperer AI enables chat-based analysis of single-cell sequencing data. You can talk to your cells & figure out the biology without writing any computer code. Paper here: www.nature.com/articles/s41.... Annotated walkthrough in a thread below (1/11)
November 11, 2025 at 12:52 PM
🗨️ Just published in Nature Biotechnology: Our CellWhisperer AI enables chat-based analysis of single-cell sequencing data. You can talk to your cells & figure out the biology without writing any computer code. Paper here: www.nature.com/articles/s41.... Annotated walkthrough in a thread below (1/11)
Reposted by JB Manent
👀
Morphogenesis and morphometry of brain folding patterns across species | bioRxiv www.biorxiv.org/content/10.1...
Morphogenesis and morphometry of brain folding patterns across species | bioRxiv www.biorxiv.org/content/10.1...
November 11, 2025 at 1:17 AM
👀
Morphogenesis and morphometry of brain folding patterns across species | bioRxiv www.biorxiv.org/content/10.1...
Morphogenesis and morphometry of brain folding patterns across species | bioRxiv www.biorxiv.org/content/10.1...
Reposted by JB Manent
In case anyone is interested, I've put that animation I made of brain development from 21-40 weeks GA on YouTube for your enjoyment/reference🤰👶🧠 Now you don't need to go to that other place anymore to find it 😁
youtu.be/C20GQ5CtVt0
Plus the code is now up!
github.com/StuartJO/Fet...
youtu.be/C20GQ5CtVt0
Plus the code is now up!
github.com/StuartJO/Fet...
Fetal Brain Development: From 21 to 40 Weeks Gestation
YouTube video by Stuart0193
youtu.be
November 13, 2025 at 1:19 PM
In case anyone is interested, I've put that animation I made of brain development from 21-40 weeks GA on YouTube for your enjoyment/reference🤰👶🧠 Now you don't need to go to that other place anymore to find it 😁
youtu.be/C20GQ5CtVt0
Plus the code is now up!
github.com/StuartJO/Fet...
youtu.be/C20GQ5CtVt0
Plus the code is now up!
github.com/StuartJO/Fet...
Reposted by JB Manent
With sequencing of Hitler's DNA making headlines, time for a reminder: analysing a polygenic score from a dead historically-significant figure won't give new insights into that person's behaviour. In a brief paper last year, we used Beethoven's genome to directly illustrate the fallacies involved.🧪👇
Notes from Beethoven’s genome
Wesseldijk et al. compare the genomic information collected from Ludwig van Beethoven
with population-based datasets used to quantify musical achievement.
www.cell.com
November 13, 2025 at 11:26 AM
With sequencing of Hitler's DNA making headlines, time for a reminder: analysing a polygenic score from a dead historically-significant figure won't give new insights into that person's behaviour. In a brief paper last year, we used Beethoven's genome to directly illustrate the fallacies involved.🧪👇