MadScientist
@mads100tist.bsky.social
Neuro and Developmental biologist. PostDoc at day. Supervillain at night. He/him #BlackLivesMatter #TransRightsAreHumanRights
@[email protected]
@[email protected]
Pinned
MadScientist
@mads100tist.bsky.social
· Sep 30
Pathway to Independence: a forecast for the future of developmental biology
ABSTRACT. In 2022, Development launched its Pathway to Independence (PI) programme, aimed at supporting postdocs as they transition to their first independent position. In 2025, we welcome our third c...
journals.biologists.com
It's online! In this series of perspectives @dev-journal.bsky.social, yours truly talks about the exciting open questions and many things to do in the field of dev bio and neuroscience #DevBio🧪 #PIsOfTomorrow journals.biologists.com/dev/article/...
Reposted by MadScientist
The November 14 #SDBPostdocSeminar with Olya Yarychkivska of @rockefeller.edu and Anthony Galenza of Stanford University has been posted. Thank you to moderators @austinseroka1.bsky.social and @dingwallaby.bsky.social. Watch here: youtu.be/C7uc-KCbzxs
SDB Ethel Browne Harvey Postdoctoral Seminar Series - Olya Yarychkivska and Anthony Galenza
YouTube video by Society for Developmental Biology
youtu.be
December 1, 2025 at 9:10 PM
The November 14 #SDBPostdocSeminar with Olya Yarychkivska of @rockefeller.edu and Anthony Galenza of Stanford University has been posted. Thank you to moderators @austinseroka1.bsky.social and @dingwallaby.bsky.social. Watch here: youtu.be/C7uc-KCbzxs
Reposted by MadScientist
✨Please join us! Bristol Zebrafish Teams Talks (previously Zoom Talks) returns for a double-feature and a new format on 12th of December at 2PM CET (1PM GMT / 8AM EST / 6:30 IST! Featuring two fintastic speakers 🤩 More details on how to join live and view recordings on our Slack tankspace ✨ 1/2
December 2, 2025 at 5:50 AM
✨Please join us! Bristol Zebrafish Teams Talks (previously Zoom Talks) returns for a double-feature and a new format on 12th of December at 2PM CET (1PM GMT / 8AM EST / 6:30 IST! Featuring two fintastic speakers 🤩 More details on how to join live and view recordings on our Slack tankspace ✨ 1/2
Reposted by MadScientist
I love paying human artists and I hate gen AI 🩵
I'm not here to fight about whether or not AI is ethical (I've made my decision and I doubt I'm gonna change yours.) I'm just here to talk about what I and many other artists have been dealing with as we adjust to a new media landscape.
I'm not here to fight about whether or not AI is ethical (I've made my decision and I doubt I'm gonna change yours.) I'm just here to talk about what I and many other artists have been dealing with as we adjust to a new media landscape.
December 1, 2025 at 7:31 PM
I love paying human artists and I hate gen AI 🩵
I'm not here to fight about whether or not AI is ethical (I've made my decision and I doubt I'm gonna change yours.) I'm just here to talk about what I and many other artists have been dealing with as we adjust to a new media landscape.
I'm not here to fight about whether or not AI is ethical (I've made my decision and I doubt I'm gonna change yours.) I'm just here to talk about what I and many other artists have been dealing with as we adjust to a new media landscape.
Reposted by MadScientist
If you run across a gen A.I. slop 🤖💩 diagram in an academic journal, I’d love to know about it! Please fill out this form:
docs.google.com/forms/d/e/1F...
Slop in journals is illuminating about journals’ quality control. And journals would like you to forget their mistakes.
#AcademicChatter
docs.google.com/forms/d/e/1F...
Slop in journals is illuminating about journals’ quality control. And journals would like you to forget their mistakes.
#AcademicChatter
Slop graphics in academic journals
Use this form to share graphics (e.g., figures, covers, graphical abstracts) made using generative A.I. that have appeared in academic journals.
The plan is to compile these slop graphics in an ope...
docs.google.com
December 1, 2025 at 6:36 PM
If you run across a gen A.I. slop 🤖💩 diagram in an academic journal, I’d love to know about it! Please fill out this form:
docs.google.com/forms/d/e/1F...
Slop in journals is illuminating about journals’ quality control. And journals would like you to forget their mistakes.
#AcademicChatter
docs.google.com/forms/d/e/1F...
Slop in journals is illuminating about journals’ quality control. And journals would like you to forget their mistakes.
#AcademicChatter
Reposted by MadScientist
We built this site to allow you to probe our single-nucleus RNA-seq data for adult #Celegans neurons (wt & daf-2 herms, and wt males v herms): cestaan.princeton.edu
and a microPub about how to use it: www.micropublication.org/journals/bio...
We hope the #Celegans community finds it useful! 🧪
and a microPub about how to use it: www.micropublication.org/journals/bio...
We hope the #Celegans community finds it useful! 🧪
CeSTAAN: An atlas of C. elegans adult neurons for fast queries of single-nucleus RNA sequencing data | microPublication
www.micropublication.org
December 1, 2025 at 3:44 PM
We built this site to allow you to probe our single-nucleus RNA-seq data for adult #Celegans neurons (wt & daf-2 herms, and wt males v herms): cestaan.princeton.edu
and a microPub about how to use it: www.micropublication.org/journals/bio...
We hope the #Celegans community finds it useful! 🧪
and a microPub about how to use it: www.micropublication.org/journals/bio...
We hope the #Celegans community finds it useful! 🧪
Reposted by MadScientist
A trans teacher at OU was specifically targeted by a student being groomed to be a Turning Point USA campus crusader.
So of course white cishet academics talk over trans people to say this is principally ideological and just what conservatives do, as if we are an issue and not people.
So of course white cishet academics talk over trans people to say this is principally ideological and just what conservatives do, as if we are an issue and not people.
December 1, 2025 at 7:33 PM
A trans teacher at OU was specifically targeted by a student being groomed to be a Turning Point USA campus crusader.
So of course white cishet academics talk over trans people to say this is principally ideological and just what conservatives do, as if we are an issue and not people.
So of course white cishet academics talk over trans people to say this is principally ideological and just what conservatives do, as if we are an issue and not people.
I find it really sad that a society whose constituents generate hundreds of beautiful scientific and artistic images both by using a scope and grabbing a pencil and paper, uses AI slop to promote something 🧪
Image description: an AI-generated advent calendar with a bunch of model organisms
Image description: an AI-generated advent calendar with a bunch of model organisms
🎄✨ Introducing 24 Days of Development!
Each day we’ll highlight one of 2025’s most influential papers published in Developmental Biology, the official journal of the Society for Developmental Biology.
Follow along! 🧬❄️🌟 #DevBio
Each day we’ll highlight one of 2025’s most influential papers published in Developmental Biology, the official journal of the Society for Developmental Biology.
Follow along! 🧬❄️🌟 #DevBio
December 1, 2025 at 3:54 PM
I find it really sad that a society whose constituents generate hundreds of beautiful scientific and artistic images both by using a scope and grabbing a pencil and paper, uses AI slop to promote something 🧪
Image description: an AI-generated advent calendar with a bunch of model organisms
Image description: an AI-generated advent calendar with a bunch of model organisms
Reposted by MadScientist
This is actually quite brilliant, up to and including the final sentence 🔥
December 1, 2025 at 11:09 AM
This is actually quite brilliant, up to and including the final sentence 🔥
Reposted by MadScientist
every trans person i see post about the OU suspension knows that the suspended target is trans & a grad student, & has an innate awareness that this is about purging trans employees. every cis person i see thinks the target is a rando professor & that this is about giving conservatives good grades
December 1, 2025 at 12:04 AM
every trans person i see post about the OU suspension knows that the suspended target is trans & a grad student, & has an innate awareness that this is about purging trans employees. every cis person i see thinks the target is a rando professor & that this is about giving conservatives good grades
Reposted by MadScientist
Remarkable story of a Georgia high school team who used CRISPR to make a rapid diagnostic test strip for Lyme disease, speeding dx from 2 weeks to days
www.cbsnews.com/news/teens-m...
www.cbsnews.com/news/teens-m...
Teens may have come up with a new way to detect, treat Lyme disease using CRISPR gene editing
To compete at iGEM, a sort of science Olympics, teens at a Georgia high school set their sights on finding a better way to detect and treat Lyme disease. Their approach uses CRISPR gene editing.
www.cbsnews.com
December 1, 2025 at 4:06 AM
Remarkable story of a Georgia high school team who used CRISPR to make a rapid diagnostic test strip for Lyme disease, speeding dx from 2 weeks to days
www.cbsnews.com/news/teens-m...
www.cbsnews.com/news/teens-m...
Reposted by MadScientist
Reposted by MadScientist
One-day-old transgenic zebrafish embryo. Credit to Dr. Kazuhide Shaun Okuda. #ZebrafishZunday 🧪
November 30, 2025 at 7:04 PM
One-day-old transgenic zebrafish embryo. Credit to Dr. Kazuhide Shaun Okuda. #ZebrafishZunday 🧪
Reposted by MadScientist
Sure, they've made an environmentally catastrophic mass hallucination disinformation plagiarism Clippy that will destabilize the world, but also their other goal is to replace human workers entirely and let us humans starve. A boycott of AI is the most important boycott of your entire life.
"All of this falls apart if humans don't adopt the tech. This is why you've seen Meta cram its lame chatbots into WhatsApp and Instagram. This is why Notepad and Paint now have useless Copilot buttons on Windows. This is why Google Gemini wants to "help you" read and reply to your emails."
Analysis: OpenAI is a loss-making machine, how can it survive?
Don't call it a bubble! Loss-making monster OpenAI is on the hook for $1.4 trillion (with a T) in compute commitments. How can this go on?
www.windowscentral.com
November 30, 2025 at 9:17 PM
Sure, they've made an environmentally catastrophic mass hallucination disinformation plagiarism Clippy that will destabilize the world, but also their other goal is to replace human workers entirely and let us humans starve. A boycott of AI is the most important boycott of your entire life.
Reposted by MadScientist
One hard part of the literacy problem in the United States is there are a lot of people -- some of them with college degrees and beyond -- who don't realize that they are bad at reading
I don't know how to reach those people
I don't know how to reach those people
November 30, 2025 at 6:17 PM
One hard part of the literacy problem in the United States is there are a lot of people -- some of them with college degrees and beyond -- who don't realize that they are bad at reading
I don't know how to reach those people
I don't know how to reach those people
Reposted by MadScientist
I just want to re-boost, because I’m the ugliness of generative AI, it’s easy to forget that there are legitimate uses that were ethically modeled —and this is one:
This is a legitimate scientific revolution in meteorology.
Also, to be clear, these models are not the AI LLMs that most people are familiar with. They are machine learning algorithms trained on observations (actually reanalysis).
Also, to be clear, these models are not the AI LLMs that most people are familiar with. They are machine learning algorithms trained on observations (actually reanalysis).
Meteorologists are surprised that the weather model that did the best job forecasting hurricanes this year was a new one, introduced by Google. AI may be the beginning of a new era of forecasting. n.pr/49MFa1M
November 30, 2025 at 1:23 PM
I just want to re-boost, because I’m the ugliness of generative AI, it’s easy to forget that there are legitimate uses that were ethically modeled —and this is one:
This is a super interesting thread 🧪
Why the brand of phase separation proposed by Tony Hyman is pseudoscientific and why it makes him incompatible with leadership of EMBL @embl.org, a major European institution in Molecular Biology #MolecularBiology
🧵A thread
#science #PhaseSeparation #BlueSkyScience #AcademicBluesky #BioSky
🧵A thread
#science #PhaseSeparation #BlueSkyScience #AcademicBluesky #BioSky
November 30, 2025 at 11:35 AM
This is a super interesting thread 🧪
Reposted by MadScientist
"Come join us!!!" —member of academic search committee that will receive 200 applications for one role and may in fact hire zero people for it
October 3, 2024 at 6:02 PM
"Come join us!!!" —member of academic search committee that will receive 200 applications for one role and may in fact hire zero people for it
Reposted by MadScientist
We are living at a time when university leadership amplifies anti-intellectual tropes and technologies
These are very troubling times
These are very troubling times
November 29, 2025 at 4:08 PM
We are living at a time when university leadership amplifies anti-intellectual tropes and technologies
These are very troubling times
These are very troubling times
Reposted by MadScientist
New work from the lab of Prof. Vatsala Thirumalai at National Centre for Biological Sciences 🇮🇳 🐟
Meha P. Jadhav of @ncbsbangalore.bsky.social et al. investigated ionic conductances driving tonic firing in Purkinje #neurons of larval zebrafish 🐟 🧠
📜 Read the #Research here: physoc.onlinelibrary.wiley.com/doi/10.1113/...
📜 Read the #Research here: physoc.onlinelibrary.wiley.com/doi/10.1113/...
November 29, 2025 at 4:41 PM
New work from the lab of Prof. Vatsala Thirumalai at National Centre for Biological Sciences 🇮🇳 🐟
Reposted by MadScientist
Got #zebrafish or other fishy news to share? Give us a ping or DM! Not only do we share to our following on social media but we post to our Celebrations channel on Slack so the whole community knows about it and can share in the excitement 😊 #ThatsHowWeShoal
November 29, 2025 at 5:24 PM
Got #zebrafish or other fishy news to share? Give us a ping or DM! Not only do we share to our following on social media but we post to our Celebrations channel on Slack so the whole community knows about it and can share in the excitement 😊 #ThatsHowWeShoal
Reposted by MadScientist
The purported disdain against "More money, more grants" is a straw man. The issue is "Why use the extra money this way?"
November 29, 2025 at 3:18 PM
The purported disdain against "More money, more grants" is a straw man. The issue is "Why use the extra money this way?"
Reposted by MadScientist
Bong Joon Ho hit me up for the squad you legend deadline.com/2025/11/bong...
November 29, 2025 at 12:49 PM
Bong Joon Ho hit me up for the squad you legend deadline.com/2025/11/bong...
Reposted by MadScientist
if you pay an artist to make art they’ll use that money to be able to keep making art, and stimulate the economy in the process! whereas if you get GenAI to make art it’ll use private equity money to drive up energy prices in the short term and in the long term cause the economy to collapse
November 29, 2025 at 3:19 AM
if you pay an artist to make art they’ll use that money to be able to keep making art, and stimulate the economy in the process! whereas if you get GenAI to make art it’ll use private equity money to drive up energy prices in the short term and in the long term cause the economy to collapse
Reposted by MadScientist
What I mean by misuse (or abuse) is that these data have very limited explanatory value. Without functional evidence of causal interactions, we cannot generate any meaningful model of the collective behaviour of the genes or transcription factors involved.
November 29, 2025 at 1:21 PM
What I mean by misuse (or abuse) is that these data have very limited explanatory value. Without functional evidence of causal interactions, we cannot generate any meaningful model of the collective behaviour of the genes or transcription factors involved.
Reposted by MadScientist
Here's a zero-cost proposal for ERC to lure US talent: condition participation in a Synergy grant to a relocation to the EU. Will help the incoming PI not only with money but also a supporting collaboration. Right now SyG is funding US labs while NIH has cut all funding to foreign collaborators.
November 29, 2025 at 11:41 AM
Here's a zero-cost proposal for ERC to lure US talent: condition participation in a Synergy grant to a relocation to the EU. Will help the incoming PI not only with money but also a supporting collaboration. Right now SyG is funding US labs while NIH has cut all funding to foreign collaborators.