DrPrincessTheSpaceCat
@prcatstronaut.bsky.social
spinster (in multiple ways) | she/her | comp bio phd/data vis | crochet | audhd | ace | queer | fat | pgh | fairy-type | dnd/lancer | stardew/fields of mistria | tng/ds9/voy | I do science for money, but I nerd for free
Pinned
Or if anyone wants a queerplatonic partner to help run a household with, I’d be down for that. Let’s Golden-Girls-it up
Reposted by DrPrincessTheSpaceCat
Can we stop with the lie that LLM/AI are inevitable ? They aren't, they cost an absolute shit ton of money.
this shit, despite its faults, is not going anywhere and people are going to have to pick their battles
Larian CEO Responds to Divinity Gen AI Backlash: 'We Are Neither Releasing a Game With Any AI Components, Nor Are We Looking at Trimming Down Teams to Replace Them With AI' - IGN
This morning, the news broke that Larian Studios, developer of Baldur's Gate 3 and the upcoming, just-announced Divinity, is apparently using generative AI behind the scenes. The backlash has been swi...
www.ign.com
December 17, 2025 at 8:48 AM
Can we stop with the lie that LLM/AI are inevitable ? They aren't, they cost an absolute shit ton of money.
Reposted by DrPrincessTheSpaceCat
This is part of why people think being lgbt+ is some new, weird trend. “Where are the queer elders?” They’re fucking dead and Reagan had a direct hand in killing them. He was more than content to sit back and let a disease that they said targeted gay men and queers take us out
December 17, 2025 at 4:49 AM
This is part of why people think being lgbt+ is some new, weird trend. “Where are the queer elders?” They’re fucking dead and Reagan had a direct hand in killing them. He was more than content to sit back and let a disease that they said targeted gay men and queers take us out
Reposted by DrPrincessTheSpaceCat
It’s really sad that basically the only way you’re going to learn any queer history now is from other queer people. That’s why it’s so important to me! And personally I don’t think any of my school textbooks touched the AIDS crisis at all
December 17, 2025 at 6:40 AM
It’s really sad that basically the only way you’re going to learn any queer history now is from other queer people. That’s why it’s so important to me! And personally I don’t think any of my school textbooks touched the AIDS crisis at all
Reposted by DrPrincessTheSpaceCat
if your policies repeatedly lose to fascism and your systems repeatedly enable fascism, perhaps your policies and your systems are part of the problem?
just a thought
just a thought
December 17, 2025 at 8:12 AM
if your policies repeatedly lose to fascism and your systems repeatedly enable fascism, perhaps your policies and your systems are part of the problem?
just a thought
just a thought
Reposted by DrPrincessTheSpaceCat
*pointing stud finder at my chest* Please…I need this
December 17, 2025 at 3:28 AM
*pointing stud finder at my chest* Please…I need this
Reposted by DrPrincessTheSpaceCat
I do not know how CEOs cannot see that they are basically pushing people's faces into cake and then saying "haha but they love it"
December 16, 2025 at 5:30 PM
I do not know how CEOs cannot see that they are basically pushing people's faces into cake and then saying "haha but they love it"
Reposted by DrPrincessTheSpaceCat
The thing I am...really curious about is how the trump cult of personality will react to his death.
The best outcome, imo, is they rabidly hate Vance and the entire government starts to implode
The best outcome, imo, is they rabidly hate Vance and the entire government starts to implode
When Trump dies-- could be at any point, who knows -- we get Vance.
They'll blame a lot of stuff on Trump AND try to fast-track an even uglier Christofascism.
We must be preparing for this now & organizing accordingly.
Grassroots activism, coalitions. Dissent. Sand in gears. GOTV.
Every angle.
They'll blame a lot of stuff on Trump AND try to fast-track an even uglier Christofascism.
We must be preparing for this now & organizing accordingly.
Grassroots activism, coalitions. Dissent. Sand in gears. GOTV.
Every angle.
December 17, 2025 at 4:13 AM
The thing I am...really curious about is how the trump cult of personality will react to his death.
The best outcome, imo, is they rabidly hate Vance and the entire government starts to implode
The best outcome, imo, is they rabidly hate Vance and the entire government starts to implode
Reposted by DrPrincessTheSpaceCat
NADPH phosphatase activity of Mesh1 controls sleep in Drosophila https://www.biorxiv.org/content/10.64898/2025.12.14.694245v1
December 17, 2025 at 4:17 AM
NADPH phosphatase activity of Mesh1 controls sleep in Drosophila https://www.biorxiv.org/content/10.64898/2025.12.14.694245v1
Reposted by DrPrincessTheSpaceCat
Become ungovernable
December 17, 2025 at 1:16 AM
Become ungovernable
Reposted by DrPrincessTheSpaceCat
Single cell and spatial characterization of the human pancreas reveals drivers of beta cell dysfunction in cystic fibrosis https://www.biorxiv.org/content/10.64898/2025.12.14.694120v1
December 17, 2025 at 4:35 AM
Single cell and spatial characterization of the human pancreas reveals drivers of beta cell dysfunction in cystic fibrosis https://www.biorxiv.org/content/10.64898/2025.12.14.694120v1
Reposted by DrPrincessTheSpaceCat
That's this whole administration, I think, they were all very obviously deeply wounded by their upbringings in ways that just broke them as human beings.
They are irreparably hurt people channeling their rage at their own spiritual wounds into violence at an incompressible scale.
They are irreparably hurt people channeling their rage at their own spiritual wounds into violence at an incompressible scale.
December 17, 2025 at 3:52 AM
That's this whole administration, I think, they were all very obviously deeply wounded by their upbringings in ways that just broke them as human beings.
They are irreparably hurt people channeling their rage at their own spiritual wounds into violence at an incompressible scale.
They are irreparably hurt people channeling their rage at their own spiritual wounds into violence at an incompressible scale.
Reposted by DrPrincessTheSpaceCat
never give up your alone time bc that’s when you get to be really disgusting
December 16, 2025 at 3:07 PM
never give up your alone time bc that’s when you get to be really disgusting
Reposted by DrPrincessTheSpaceCat
There should be a constitutional mechanism for removing a president. Not impeachment, something that actually works, maybe like a catapult
December 17, 2025 at 3:08 AM
There should be a constitutional mechanism for removing a president. Not impeachment, something that actually works, maybe like a catapult
Reposted by DrPrincessTheSpaceCat
frankly 'electability' should be near the bottom of the concerns for the 2028 primary, Trump will be either attempting an unconstitutional power grab as half a corpse or one of his juiceless, infighting successors will be trying to patch the Trump coalition back together and failing.
It will genuinely be a struggle for any nominee to lose after the next three years, but Gruesome Newsom could manage the enthusiasm collapse it would take
Gavin Newsom is Mitt Romney for the Democrats, a department store mannequin who will lose in a general election
December 17, 2025 at 2:55 AM
frankly 'electability' should be near the bottom of the concerns for the 2028 primary, Trump will be either attempting an unconstitutional power grab as half a corpse or one of his juiceless, infighting successors will be trying to patch the Trump coalition back together and failing.
Reposted by DrPrincessTheSpaceCat
Pretty funny to watch all the Bluesky mil guys get mad about progressives going "no blood for oil, part III" only for Trump to just tweet out "to be clear we are spilling their blood to obtain oil"
Trump: "Venezuela is completely surrounded by the largest Armada ever assembled ... It will only get bigger, and the shock to them will be like nothing they have ever seen before — Until such time as they return to the USA all of the Oil, Land, and other Assets that they previously stole from us."
December 17, 2025 at 4:54 AM
Pretty funny to watch all the Bluesky mil guys get mad about progressives going "no blood for oil, part III" only for Trump to just tweet out "to be clear we are spilling their blood to obtain oil"
Reposted by DrPrincessTheSpaceCat
very grimly ironic that our government run by podcasters sucks at true crime
Gotta say it's mindblowing to me that the Brown shooter is still at large and they don't even seem to have identified who they're looking for.
December 16, 2025 at 7:19 PM
very grimly ironic that our government run by podcasters sucks at true crime
Reposted by DrPrincessTheSpaceCat
Watch John Fetterman vote for child abuse and rape.
December 16, 2025 at 11:49 PM
Watch John Fetterman vote for child abuse and rape.
Reposted by DrPrincessTheSpaceCat
In my case, this painstaking labor in the process through which the science gets done. Science isn't measuring stuff in a lab. It's thinking deeply, extracting the heart of idea from the soup of thoughts running through my mind, molding it, and finding a way to communicate that idea to others.
December 16, 2025 at 11:46 PM
In my case, this painstaking labor in the process through which the science gets done. Science isn't measuring stuff in a lab. It's thinking deeply, extracting the heart of idea from the soup of thoughts running through my mind, molding it, and finding a way to communicate that idea to others.
Reposted by DrPrincessTheSpaceCat
They want racism. They want racism and sexism from people who make them feel good about it,
That’s the base of Bari Weiss. It’s not just “the propaganda” they want assurance via her mediocrity and the outward abuse of the marginalized so they can be the nice guys
That’s the base of Bari Weiss. It’s not just “the propaganda” they want assurance via her mediocrity and the outward abuse of the marginalized so they can be the nice guys
A lot of these guys don't get that Fox News viewers don't want 'fair and balanced' news or even 'right-wing biased' news. They want propaganda! They want to not have to think!
December 17, 2025 at 12:03 AM
They want racism. They want racism and sexism from people who make them feel good about it,
That’s the base of Bari Weiss. It’s not just “the propaganda” they want assurance via her mediocrity and the outward abuse of the marginalized so they can be the nice guys
That’s the base of Bari Weiss. It’s not just “the propaganda” they want assurance via her mediocrity and the outward abuse of the marginalized so they can be the nice guys
Reposted by DrPrincessTheSpaceCat
apologies to everyone who thought they had a coolass name but
December 16, 2025 at 8:50 PM
apologies to everyone who thought they had a coolass name but
Reposted by DrPrincessTheSpaceCat
Automation workflow for high-throughput arrayed plasmid DNA preparation and quantification. https://www.biorxiv.org/content/10.64898/2025.12.13.694144v1
December 17, 2025 at 12:07 AM
Automation workflow for high-throughput arrayed plasmid DNA preparation and quantification. https://www.biorxiv.org/content/10.64898/2025.12.13.694144v1
Reposted by DrPrincessTheSpaceCat
oh look a real unemployment problem
US jobless rate for Blacks and teens surges in November reut.rs/49gilCM
US jobless rate for Blacks and teens surges in November
The unemployment rate for two U.S. groups that are often the most vulnerable to job loss in a softening economy - Blacks and teenagers - surged to the highest levels in more than four years in November, Labor Department data showed on Tuesday.
reut.rs
December 16, 2025 at 8:28 PM
oh look a real unemployment problem
Reposted by DrPrincessTheSpaceCat
I don’t understand how anyone can experience a sucky situation and be all “yes other people should have to deal with this bullshit because I did” instead of being like “holy shit this fucking sucks let’s make it so no one deals with this ever again”.
December 16, 2025 at 9:35 PM
I don’t understand how anyone can experience a sucky situation and be all “yes other people should have to deal with this bullshit because I did” instead of being like “holy shit this fucking sucks let’s make it so no one deals with this ever again”.
Reposted by DrPrincessTheSpaceCat
Bacterial genomes encode a rich repertoire of antiphage systems, but we still know surprisingly little about when these systems are actually expressed.
In this preprint, Lucas Paoli et al, ask what shapes antiphage systems expression in native contexts.
www.biorxiv.org/content/10.6...
In this preprint, Lucas Paoli et al, ask what shapes antiphage systems expression in native contexts.
www.biorxiv.org/content/10.6...
Environment and physiology shape antiphage system expression
Bacteria and archaea encode on average ten antiphage systems. Quorum sensing, cellular, or transcription factors can regulate specific systems (CRISPR-Cas, CBASS). Yet, a systematic assessment of anti...
www.biorxiv.org
December 15, 2025 at 9:49 PM
Bacterial genomes encode a rich repertoire of antiphage systems, but we still know surprisingly little about when these systems are actually expressed.
In this preprint, Lucas Paoli et al, ask what shapes antiphage systems expression in native contexts.
www.biorxiv.org/content/10.6...
In this preprint, Lucas Paoli et al, ask what shapes antiphage systems expression in native contexts.
www.biorxiv.org/content/10.6...
Reposted by DrPrincessTheSpaceCat
Gritty 2028
December 16, 2025 at 9:52 PM
Gritty 2028