Ian Myles, MD/MPH
@lcdriammdmph.bsky.social
Researching the intersection of the microbiome, environment, and allergic disease. Views are my own.
https://irp.nih.gov/pi/ian-myles
https://irp.nih.gov/pi/ian-myles
"Draw me a diagram on the causes of atopic dermatitis" per Gemini... I don't think LLMs will displace real scientists a time soon.
December 22, 2025 at 10:51 PM
"Draw me a diagram on the causes of atopic dermatitis" per Gemini... I don't think LLMs will displace real scientists a time soon.
Reposted by Ian Myles, MD/MPH
Wilmington Notch Falls, West Branch Ausable River, Wilmington, NY. 55 feet. 9/9/24.
44.3498738, -73.8607370
#newyork
#waterfalls
#photography
#waterfallphotography
#longexposure
#chasingwaterfalls
#landscapephotography
#hiking
#outdoors
#explore
#nature
#travelphotography
44.3498738, -73.8607370
#newyork
#waterfalls
#photography
#waterfallphotography
#longexposure
#chasingwaterfalls
#landscapephotography
#hiking
#outdoors
#explore
#nature
#travelphotography
December 21, 2025 at 11:47 AM
Wilmington Notch Falls, West Branch Ausable River, Wilmington, NY. 55 feet. 9/9/24.
44.3498738, -73.8607370
#newyork
#waterfalls
#photography
#waterfallphotography
#longexposure
#chasingwaterfalls
#landscapephotography
#hiking
#outdoors
#explore
#nature
#travelphotography
44.3498738, -73.8607370
#newyork
#waterfalls
#photography
#waterfallphotography
#longexposure
#chasingwaterfalls
#landscapephotography
#hiking
#outdoors
#explore
#nature
#travelphotography
A really awesome thread about an example of the limits of using AI to generate new discoveries.
Absolutely right.
AI might be able to summarize (poorly) what we currently know, but a major goal of historical research is to find the hidden surprises out there.
Let me illustrate …
AI might be able to summarize (poorly) what we currently know, but a major goal of historical research is to find the hidden surprises out there.
Let me illustrate …
Not a historian but like to research. The AI might summarize what I'm looking for, but it doesn't find what I'm *not* looking for. The book on the shelf next to the one I wanted. The insight in chapter 6 based on the quote I needed from chapter 4.
December 21, 2025 at 5:51 PM
A really awesome thread about an example of the limits of using AI to generate new discoveries.
Reposted by Ian Myles, MD/MPH
The #ColumbiaGorge is a perfect place to unwind and escape the worlds problems.
Lucky to live so close.
Have a peaceful day.
Nature photo day 338
#nature #photography #eastcoastkin #waterfallWednesday #hiking #photographersofbluesky #peace #landscapephotography #pnw #river #creek #forest
Lucky to live so close.
Have a peaceful day.
Nature photo day 338
#nature #photography #eastcoastkin #waterfallWednesday #hiking #photographersofbluesky #peace #landscapephotography #pnw #river #creek #forest
December 17, 2025 at 2:07 PM
The #ColumbiaGorge is a perfect place to unwind and escape the worlds problems.
Lucky to live so close.
Have a peaceful day.
Nature photo day 338
#nature #photography #eastcoastkin #waterfallWednesday #hiking #photographersofbluesky #peace #landscapephotography #pnw #river #creek #forest
Lucky to live so close.
Have a peaceful day.
Nature photo day 338
#nature #photography #eastcoastkin #waterfallWednesday #hiking #photographersofbluesky #peace #landscapephotography #pnw #river #creek #forest
Reposted by Ian Myles, MD/MPH
December 14, 2025 at 2:52 AM
Reposted by Ian Myles, MD/MPH
Excited to announce that my next book, I AM THE NIGHT, not only has a great cover but is available for pre-order now: us.macmillan.com/books/978125...
December 12, 2025 at 11:18 PM
Excited to announce that my next book, I AM THE NIGHT, not only has a great cover but is available for pre-order now: us.macmillan.com/books/978125...
Reposted by Ian Myles, MD/MPH
We don’t give a damn for the whole state of Michigan, the whole state of Michigan, the whole state of Michigan. We don’t give a damn for the whole state of Michigan…
WE’RE FROM OHIO!!!!!!
Let’s Go Buckeyes!!!!!! 🌰
WE’RE FROM OHIO!!!!!!
Let’s Go Buckeyes!!!!!! 🌰
November 29, 2025 at 8:19 PM
We don’t give a damn for the whole state of Michigan, the whole state of Michigan, the whole state of Michigan. We don’t give a damn for the whole state of Michigan…
WE’RE FROM OHIO!!!!!!
Let’s Go Buckeyes!!!!!! 🌰
WE’RE FROM OHIO!!!!!!
Let’s Go Buckeyes!!!!!! 🌰
Reposted by Ian Myles, MD/MPH
top notch mascottin'
November 29, 2025 at 8:06 PM
top notch mascottin'
Reposted by Ian Myles, MD/MPH
I wrote a little bit about the "missing heritability" question and several recent studies that have brought it to a close. A short 🧵
The missing heritability question is now (mostly) answered
Not with a bang but with a whimper
theinfinitesimal.substack.com
November 21, 2025 at 10:34 PM
I wrote a little bit about the "missing heritability" question and several recent studies that have brought it to a close. A short 🧵
Reposted by Ian Myles, MD/MPH
It only took us several decades and dozens Nature/Nature Genetics papers but we finally got to the conclusion that plant and animal breeders (and Lewontin) arrived at from the start: twin studies suck!
I wrote a little bit about the "missing heritability" question and several recent studies that have brought it to a close. A short 🧵
The missing heritability question is now (mostly) answered
Not with a bang but with a whimper
theinfinitesimal.substack.com
November 21, 2025 at 11:40 PM
It only took us several decades and dozens Nature/Nature Genetics papers but we finally got to the conclusion that plant and animal breeders (and Lewontin) arrived at from the start: twin studies suck!
Reposted by Ian Myles, MD/MPH
Rudy Bridges is younger than the Sitting President of the United States and 29 sitting United States Senators
It’s useful for people of my generation to be reminded that this wasn’t that long ago. Ruby Bridges isn’t just still alive—she’s only 71, not ancient!
65 years ago on Nov. 14, little Ruby Bridges was escorted into an all-white elementary school in New Orleans. Norman Rockwell, renowned for blissful depictions of Americana, did this remarkable painting for Look magazine. Printed as a double page, over-size spread, it's his masterpiece.
November 15, 2025 at 3:44 PM
Rudy Bridges is younger than the Sitting President of the United States and 29 sitting United States Senators
Reposted by Ian Myles, MD/MPH
Every tech company eventually either reinvents the bus or reinvents phrenology
bro are you fucking kidding me
November 6, 2025 at 7:05 PM
Every tech company eventually either reinvents the bus or reinvents phrenology
Reposted by Ian Myles, MD/MPH
he’d warned that fucker not to play wonderwall
October 25, 2025 at 10:11 PM
he’d warned that fucker not to play wonderwall
Reposted by Ian Myles, MD/MPH
This sounds ominous. Medicaid, even for those who can keep it, will turn to shit.
October 23, 2025 at 2:05 AM
This sounds ominous. Medicaid, even for those who can keep it, will turn to shit.
Reposted by Ian Myles, MD/MPH
The entire "free speech on campus" moral panic was manufactured to blackmail us into making space in intellectual life for bigots and charlatans who couldn't get there on their own merits. Its a DEI scheme for fascism. Congratulations to everyone who took it at face value.
“Following his lecture, Yarvin will debate the legendary British historian David Starkey on history and the future of conservatism.” Everything about this is so cursed. Masks off at the University of Oxford.
October 20, 2025 at 2:13 PM
The entire "free speech on campus" moral panic was manufactured to blackmail us into making space in intellectual life for bigots and charlatans who couldn't get there on their own merits. Its a DEI scheme for fascism. Congratulations to everyone who took it at face value.
Reposted by Ian Myles, MD/MPH
In 2018, Charles Murray challenged me to a bet: "We will understand IQ genetically—I think most of the picture will have been filled in by 2025—there will still be blanks—but we’ll know basically what’s going on." It's now 2025, and I claim a win. I write about it in The Atlantic.
Your Genes Are Simply Not Enough to Explain How Smart You Are
Seven years ago, I took a bet with Charles Murray about whether we’d basically understand the genetics of intelligence by now.
www.theatlantic.com
October 13, 2025 at 1:33 PM
In 2018, Charles Murray challenged me to a bet: "We will understand IQ genetically—I think most of the picture will have been filled in by 2025—there will still be blanks—but we’ll know basically what’s going on." It's now 2025, and I claim a win. I write about it in The Atlantic.
Reposted by Ian Myles, MD/MPH
every single tech idea is like “soon our robots will be capable of playing catch with your kid, freeing you up to spend more time working on your employers’ spreadsheets”
October 11, 2025 at 2:07 PM
every single tech idea is like “soon our robots will be capable of playing catch with your kid, freeing you up to spend more time working on your employers’ spreadsheets”
Reposted by Ian Myles, MD/MPH
Dear Editor,
Thank you for submitting your review request to Tomer Ullman.
As you may know, we decline a substantial proportion of reviews requests without sending them out for further evaluation. After careful consideration, we regret to say we cannot offer to take on this review.
Thank you for submitting your review request to Tomer Ullman.
As you may know, we decline a substantial proportion of reviews requests without sending them out for further evaluation. After careful consideration, we regret to say we cannot offer to take on this review.
September 24, 2025 at 1:01 PM
Dear Editor,
Thank you for submitting your review request to Tomer Ullman.
As you may know, we decline a substantial proportion of reviews requests without sending them out for further evaluation. After careful consideration, we regret to say we cannot offer to take on this review.
Thank you for submitting your review request to Tomer Ullman.
As you may know, we decline a substantial proportion of reviews requests without sending them out for further evaluation. After careful consideration, we regret to say we cannot offer to take on this review.
Reposted by Ian Myles, MD/MPH
Re-upping for no particular reason...
I spend far too much time thinking about this chart and what is happening in US politics.
September 20, 2025 at 1:29 PM
Re-upping for no particular reason...
Reposted by Ian Myles, MD/MPH
Reposted by Ian Myles, MD/MPH
I don't think it was a financial decision at all. It was all about having power over other human beings, especially their own workers and servants, and MeToo, BLM and 3% unemployment all were huge threats to that power.
Last week someone made this point, a lot of money people (including tech) made a very clear, very calculated decision that authoritarianism, even a corrupt kleptocracy, was better for them financially than risking Dems doing a wealth tax/tax fairness etc. It was an eyes-wide-open choice.
Cuban explains why companies like Intel are happy to give fascists a cut. The wealthiest people in the country see it as a smaller sacrifice than what progressives are proposing in higher taxes.
August 24, 2025 at 4:38 AM
I don't think it was a financial decision at all. It was all about having power over other human beings, especially their own workers and servants, and MeToo, BLM and 3% unemployment all were huge threats to that power.
Reposted by Ian Myles, MD/MPH
Reposted by Ian Myles, MD/MPH
If someone you know buys into claims about "genetic optimization" of embryos using polygenic scores of cognition, just send them our 2024 paper on Beethoven & musicality. We wrote it to help communicate limits of individual-level genetic predictions & complexity of links between DNA & behaviour. 🧪👇
Notes from Beethoven’s genome
Wesseldijk et al. compare the genomic information collected from Ludwig van Beethoven
with population-based datasets used to quantify musical achievement.
www.cell.com
August 7, 2025 at 11:10 AM
If someone you know buys into claims about "genetic optimization" of embryos using polygenic scores of cognition, just send them our 2024 paper on Beethoven & musicality. We wrote it to help communicate limits of individual-level genetic predictions & complexity of links between DNA & behaviour. 🧪👇