Sean Gibbons 🦠💩
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gibbological.bsky.social
Sean Gibbons 🦠💩
@gibbological.bsky.social
microbiome researcher | associate professor @isbscience.org | affiliate prof @uwbioe.bsky.social | ecology, evolution, and systems biology of 💩 🦠 | precision/personalized nutrition/medicine ⚕️ | 🏳️‍🌈 he/him | lab website: gibbons.isbscience.org
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💥Personalized C. difficile colonization risk prediction and probiotic therapy assessment in the human gut💥

I'm very excited about this work, driven by Alex Carr & co-supervised by @cdiener.com

@cp-cellsystems.bsky.social @isbscience.org @nitinbaliga.bsky.social

www.cell.com/cell-systems...

🧵...
Personalized Clostridioides difficile colonization risk prediction and probiotic therapy assessment in the human gut
Carr et al. show how microbial community-scale metabolic models (MCMMs) predict personalized Clostridioides difficile colonization risk and probiotic efficacy. MCMMs reveal key metabolic strategies ex...
www.cell.com
Reposted by Sean Gibbons 🦠💩
Former US military lawyers speak out:

"The Former JAGs Working Group unanimously considers both the giving and the execution of these orders, if true, to constitute war crimes, murder, or both."

Statement on Media Reports of Pentagon “No Quarter” Orders in Caribbean Boat Strikes

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November 29, 2025 at 8:10 PM
Reposted by Sean Gibbons 🦠💩
NOVEMBER ISSUE | Our Featured PERSPECTIVE is on "Credible inferences in microbiome research: ensuring rigour, reproducibility and relevance in the era of AI"

www.nature.com/articles/s41...

#Gastrosky #Microsky
October 27, 2025 at 3:42 PM
Reposted by Sean Gibbons 🦠💩
Our NOVEMBER ISSUE introducing our new Series of articles on NUTRITION is live! Intestinal mucosa, parental diet and offspring health, LLMs and clinical decision, AI and microbiome, and much more!

www.nature.com/nrgastro/vol...
October 27, 2025 at 3:42 PM
Reposted by Sean Gibbons 🦠💩
Happy Science Friday! Here’s what we’re covering today on the show. Listen on your local public radio station, 2-4 p.m. ET. 🏆 🏋🏽🪴

Learn more here: buff.ly/uWWEb7I
November 28, 2025 at 3:10 PM
Reposted by Sean Gibbons 🦠💩
Here's a gift link: www.wsj.com/world/russia...
November 29, 2025 at 4:46 PM
Reposted by Sean Gibbons 🦠💩
Out after peer-review: www.science.org/doi/full/10....

Our bottom line stayed: never use leave-one-out cross-validation as it has inherent train-test leakage. Consider our Rebalanced version instead!

We now also account for regression and nested cross-validation, with more extensive benchmarking.
November 28, 2025 at 7:32 PM
Reposted by Sean Gibbons 🦠💩
For context, Trump is just 2 (yes, two) points higher now than he was in the Gallup poll conducted almost entirely after the Jan 6 riot.

news.gallup.com/poll/699221/...
Gallup poll | 11/3-11/25

President Trump approval
Disapprove 60% (+6)
Approve 36% (-5)

news.gallup.com/poll/699221/...
November 28, 2025 at 6:20 PM
Reposted by Sean Gibbons 🦠💩
Long read Metagenomics, #phage and #prophage in the gut by Ami Bhatt's group. Beautiful data showing changes in phages over two years

#phagesky

www.nature.com/articles/s41...
Long-read metagenomics reveals phage dynamics in the human gut microbiome - Nature
Complex prophage integration dynamics, including low-level induction, cross-family host range and transposase-mediated mobilization, challenge existing paradigms and deepen our understanding of phage–...
www.nature.com
November 26, 2025 at 9:55 PM
Reposted by Sean Gibbons 🦠💩
A 60-year old man in Germany became the seventh person with HIV to be announced free of the virus after receiving a stem-cell transplant

go.nature.com/48C68Ib
Seventh patient ‘cured’ of HIV: why scientists are excited
A man in Germany is HIV-free after receiving stem cells that are not resistant to the virus.
go.nature.com
November 26, 2025 at 5:30 PM
Reposted by Sean Gibbons 🦠💩
tfw u need seven samurai
November 26, 2025 at 1:42 AM
Reposted by Sean Gibbons 🦠💩
Under President Trump, electricity prices are surging — up 11%! — leaving millions behind on their utility bills, with past-due balances at an all-time high.

American families deserve better.
November 26, 2025 at 3:45 PM
We're at 735 registrants and counting! 🎉🦠

If you haven't registered yet, don't miss out on this exciting (free) symposium on gut microbial metabolites and their impacts on host health.

Please share with your networks. 🔗👇

isbscience.org/events/2025-...
November 26, 2025 at 5:19 PM
Reposted by Sean Gibbons 🦠💩
The stock market's gains are being overwhelmingly driven by seven Big Tech companies who have invested heavily in AI, which has made tech oligarchs even wealthier.

But when that AI bubble bursts, the rest of us will be stuck holding the bag.

Be warned.
November 25, 2025 at 11:01 PM
Reposted by Sean Gibbons 🦠💩
Breaking News: Viola Fletcher, the oldest survivor of the Tulsa Race Massacre who testified a century later in Congress to the terror she witnessed in the hope of winning reparations, died at 111. nyti.ms/4or9B1e
November 24, 2025 at 10:21 PM
Reposted by Sean Gibbons 🦠💩
I have friends in the animal rights world who — months back — thought there would be some sort of silver lining to the RFK regime, and I want to emphasize that cancelling HIV research and euthanizing a ton of chimps is not a silver lining for anyone involved.
November 24, 2025 at 8:32 PM
Reposted by Sean Gibbons 🦠💩
A toxin-secreting gut bacterium may fuel ulcerative colitis by killing protective immune cells that maintain intestinal homeostasis, according to a new study in Science.

The findings suggest potential for new treatment strategies. https://scim.ag/4rjvjqA
An Aeromonas variant that produces aerolysin promotes susceptibility to ulcerative colitis
Ulcerative colitis (UC) is a severe inflammatory bowel disease affecting millions of people worldwide, but the factors driving the condition are poorly understood. In tissue samples from individuals w...
scim.ag
November 24, 2025 at 10:00 PM
Reposted by Sean Gibbons 🦠💩
This is absolutely f'ing horrifying.
Emmanuel, a 15-year-old with intellectual disabilities, wandered away from his mom’s fruit stand in October.

She reported him missing to Houston police. But instead of reuniting them, the city turned him over to ICE.

“They’re failing all of us,” his mom said.

thebarbedwire.com/2025/11/24/d...
A Disabled Child’s Mom Reported Him Missing. He Was Locked Away by Federal Immigration Authorities for 48 Days.
Emmanuel, a 15-year-old who has an intellectual disability, walked away from his mom’s fruit stand in October. Houston Police called ICE.
thebarbedwire.com
November 24, 2025 at 3:13 PM
Reposted by Sean Gibbons 🦠💩
Open faculty position (Assistant or Associate) in UW Medical Genetics. As you might expect, faculty often end up also interacting with Genome Sciences, so we're hoping for some great prospects! Note the clinical requirements for the position. apply.interfolio.com/176466
Apply - Interfolio {{$ctrl.$state.data.pageTitle}} - Apply - Interfolio
apply.interfolio.com
November 24, 2025 at 7:23 PM
Reposted by Sean Gibbons 🦠💩
This is concerning.

NIH is changing their policy so that staff have to prepare justification for every application that is funded BUT NO DOCUMENTATION FOR APPLICATIONS THAT ARE SKIPPED (BASED ON PERCENTILES).

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November 24, 2025 at 12:29 AM
Reposted by Sean Gibbons 🦠💩
And another thing: we're not enron. please dont put in the newspaper that we're like enron
In the memo, “Nvidia also responds to claims that the ‘current situation is analogous to historical accounting frauds (Enron, WorldCom, Lucent) that featured vendor financing and SPVs [special purpose vehicles.)’”

@barrons.com $NVDA
@firstadopter.bsky.social
www.barrons.com/articles/nvi...
November 24, 2025 at 7:36 PM
Reposted by Sean Gibbons 🦠💩
America needs more patriots like Senator Mark Kelly and fewer miserable cowards like Donald Trump and Pete Hegseth.
Sen. Mark Kelly facing military investigation after clashing with Trump
A statement from the Pentagon said all service members have a "legal obligation" to "obey lawful orders and that orders are presumed to be lawful."
www.axios.com
November 24, 2025 at 7:36 PM
Reposted by Sean Gibbons 🦠💩
Due to the shutdown, NIH cancelled >370 study sections, impacting >24,000 applications

Rescheduled meetings will only discuss 30-35% of applications, have simplified summary statements (no narrative paragraph), and a new category - "competitive but not discussed"

grants.nih.gov/grants/guide...
NOT-OD-26-012: Updated Guidance on Reopening of NIH Extramural Activities Following the October 1, 2025 - Lapse in Appropriations
NIH Funding Opportunities and Notices in the NIH Guide for Grants and Contracts: Updated Guidance on Reopening of NIH Extramural Activities Following the October 1, 2025 - Lapse in Appropriations NOT-...
grants.nih.gov
November 24, 2025 at 6:55 PM