Matt Manion
@scarytonin.bsky.social
Doctor of Neuroscience by day, scared of everything by night. Bioinformatician. Also dog dad, tabletop gamer, and craft beer enthusiast. UAW 2750 (He/Him)
Reposted by Matt Manion
generative AI has become widely available in the summer of 2022 and entered mainstream in 2023
people are working themselves up in a frenzy, convinced they're utterly helpless without software younger than still-fresh canned tuna. we have been making art for at least 50,000 years, get a grip
people are working themselves up in a frenzy, convinced they're utterly helpless without software younger than still-fresh canned tuna. we have been making art for at least 50,000 years, get a grip
February 6, 2026 at 11:13 PM
generative AI has become widely available in the summer of 2022 and entered mainstream in 2023
people are working themselves up in a frenzy, convinced they're utterly helpless without software younger than still-fresh canned tuna. we have been making art for at least 50,000 years, get a grip
people are working themselves up in a frenzy, convinced they're utterly helpless without software younger than still-fresh canned tuna. we have been making art for at least 50,000 years, get a grip
Reposted by Matt Manion
In about a week, the Senate is expected to vote on giving ICE and Border Patrol BILLIONS MORE in funding. Together WE can stop that. Call your senator TODAY and urge them to vote NO!
#ICEout #WeFeedYou
#ICEout #WeFeedYou
February 7, 2026 at 1:07 AM
In about a week, the Senate is expected to vote on giving ICE and Border Patrol BILLIONS MORE in funding. Together WE can stop that. Call your senator TODAY and urge them to vote NO!
#ICEout #WeFeedYou
#ICEout #WeFeedYou
Reposted by Matt Manion
Just because good news is worth celebrating:
There is now a Prep medication that is an *every six month* injection.
HIV has, effectively, a vaccination.
There is now a Prep medication that is an *every six month* injection.
HIV has, effectively, a vaccination.
February 7, 2026 at 12:12 AM
Just because good news is worth celebrating:
There is now a Prep medication that is an *every six month* injection.
HIV has, effectively, a vaccination.
There is now a Prep medication that is an *every six month* injection.
HIV has, effectively, a vaccination.
Reposted by Matt Manion
it's obvious but needs to be said: there is no bottom to any of this because we are seeing inside their minds what acts and words occur before the guard rails come off and while some semblance of rule of law still exists.
February 6, 2026 at 1:20 PM
it's obvious but needs to be said: there is no bottom to any of this because we are seeing inside their minds what acts and words occur before the guard rails come off and while some semblance of rule of law still exists.
Reposted by Matt Manion
JUSTIFIED “FUCK ICE” CHANTS #AEWDynamite
February 5, 2026 at 3:04 AM
JUSTIFIED “FUCK ICE” CHANTS #AEWDynamite
Reposted by Matt Manion
NEW: Elon Musk has insisted that Jeffrey Epstein invited him to the notorious island and he declined. But new emails show the opposite -- Musk was practically begging to party with Epstein in the Caribbean, years after Epstein's sex convictions were public knowledge
futurism.com/future-socie...
futurism.com/future-socie...
Elon Musk Emailed Extensively With Jeffrey Epstein, Begging to Visit His Notorious Island
Newly released documents show how Elon Musk extensively communicated with Jeffrey Epstein to plan parties and trips to his island.
futurism.com
January 30, 2026 at 8:25 PM
NEW: Elon Musk has insisted that Jeffrey Epstein invited him to the notorious island and he declined. But new emails show the opposite -- Musk was practically begging to party with Epstein in the Caribbean, years after Epstein's sex convictions were public knowledge
futurism.com/future-socie...
futurism.com/future-socie...
Reposted by Matt Manion
they should pass a law that says ICE has to follow the law
January 27, 2026 at 3:04 PM
they should pass a law that says ICE has to follow the law
Reposted by Matt Manion
MLK was only 39 when he was killed. Growing up, I thought that was old. But I’m 43 now and I’m stunned by the burden he shouldered at such a young age. I’m also a lot more aware of how hard it is, at any age, to carry the hopes and dreams of an oppressed people on your shoulders, as so many do.
January 19, 2026 at 2:55 PM
MLK was only 39 when he was killed. Growing up, I thought that was old. But I’m 43 now and I’m stunned by the burden he shouldered at such a young age. I’m also a lot more aware of how hard it is, at any age, to carry the hopes and dreams of an oppressed people on your shoulders, as so many do.
Reposted by Matt Manion
In the January cold, find a sunny spot and tuck in. #australianshepherd #dogsofbluesky
January 17, 2026 at 8:29 PM
In the January cold, find a sunny spot and tuck in. #australianshepherd #dogsofbluesky
Reposted by Matt Manion
This drops on newsletter at 10am if you’re looking for more info on the DWJ covers and how to get them.
Also, if you order anything else off my websto’ as part of your order, I’ll be donating that amount as well.
As always, very much appreciate any signal boosting.
Also, if you order anything else off my websto’ as part of your order, I’ll be donating that amount as well.
As always, very much appreciate any signal boosting.
January 14, 2026 at 5:59 AM
This drops on newsletter at 10am if you’re looking for more info on the DWJ covers and how to get them.
Also, if you order anything else off my websto’ as part of your order, I’ll be donating that amount as well.
As always, very much appreciate any signal boosting.
Also, if you order anything else off my websto’ as part of your order, I’ll be donating that amount as well.
As always, very much appreciate any signal boosting.
Reposted by Matt Manion
Teaming up with Brody King and Daniel Warren Johnson to drop a brand new Tales from the Road variant cover to help families that have been affected by ICE raids in Minnesota.
January 13, 2026 at 12:25 PM
Teaming up with Brody King and Daniel Warren Johnson to drop a brand new Tales from the Road variant cover to help families that have been affected by ICE raids in Minnesota.
Reposted by Matt Manion
[something horrific]
"dont take the bait"
[something worse]
"dont take the bait"
[something worse]
"dont take the bait"
[something worse]
"dont take the bait"
[something worse]
"dont take the bait"
[something worse]
"dont take the bait"
...
"dont take the bait"
[something worse]
"dont take the bait"
[something worse]
"dont take the bait"
[something worse]
"dont take the bait"
[something worse]
"dont take the bait"
[something worse]
"dont take the bait"
...
Incredible that people have careers based around telling those who are struggling to keep their chin up and not react because "They're clearly [doing worse thing than the last thing] to bait an excuse to [do even worse thing]."
It's a ratchet. You're describing a ratchet. You are selling ratchets.
It's a ratchet. You're describing a ratchet. You are selling ratchets.
January 10, 2026 at 8:17 PM
[something horrific]
"dont take the bait"
[something worse]
"dont take the bait"
[something worse]
"dont take the bait"
[something worse]
"dont take the bait"
[something worse]
"dont take the bait"
[something worse]
"dont take the bait"
...
"dont take the bait"
[something worse]
"dont take the bait"
[something worse]
"dont take the bait"
[something worse]
"dont take the bait"
[something worse]
"dont take the bait"
[something worse]
"dont take the bait"
...
Reposted by Matt Manion
Dems are still approaching this wrong. I just saw a BBC host ask a state senator if Tim Walz should call out the National Guard.
He says, "No, because Minnesotans know how to protest peacefully."
THAT'S NOT WHO THE GUARD IS FOR. THE GUARD IS TO PROTECT THE PROTESTERS FROM LAWLESS FEDERAL AGENTS.
He says, "No, because Minnesotans know how to protest peacefully."
THAT'S NOT WHO THE GUARD IS FOR. THE GUARD IS TO PROTECT THE PROTESTERS FROM LAWLESS FEDERAL AGENTS.
January 8, 2026 at 12:39 AM
Dems are still approaching this wrong. I just saw a BBC host ask a state senator if Tim Walz should call out the National Guard.
He says, "No, because Minnesotans know how to protest peacefully."
THAT'S NOT WHO THE GUARD IS FOR. THE GUARD IS TO PROTECT THE PROTESTERS FROM LAWLESS FEDERAL AGENTS.
He says, "No, because Minnesotans know how to protest peacefully."
THAT'S NOT WHO THE GUARD IS FOR. THE GUARD IS TO PROTECT THE PROTESTERS FROM LAWLESS FEDERAL AGENTS.
Reposted by Matt Manion
the thing about that “first they came for” poem is that we’re at least halfway through it, and it’s not a very long poem
January 8, 2026 at 2:15 AM
the thing about that “first they came for” poem is that we’re at least halfway through it, and it’s not a very long poem
Reposted by Matt Manion
Is it strong or weak to throw trans people under the bus? Is it strong or weak to target and destroy homeless encampments? Is it strong or weak to adopt your nominal enemy's platform rather than stand on principles? Gtfoh.
“Remember: be vulgar, be trivial, be offensive. Just don’t be weak.”
www.theatlantic.com/politics/202...
www.theatlantic.com/politics/202...
The Front-Runner
California’s Gavin Newsom would rather be wrong than weak.
www.theatlantic.com
January 7, 2026 at 4:20 AM
Is it strong or weak to throw trans people under the bus? Is it strong or weak to target and destroy homeless encampments? Is it strong or weak to adopt your nominal enemy's platform rather than stand on principles? Gtfoh.
Reposted by Matt Manion
Reposted by Matt Manion
Happy New Year to the haters, the losers, and the far left marxist transgender extremists, which I think covers everyone here.
January 1, 2026 at 12:58 AM
Happy New Year to the haters, the losers, and the far left marxist transgender extremists, which I think covers everyone here.
Reposted by Matt Manion
hey let’s see how things are going in 2026 in the star trek timeline
January 1, 2026 at 5:06 AM
hey let’s see how things are going in 2026 in the star trek timeline
Reposted by Matt Manion
Moody threw a rave for herself in the backyard.
December 27, 2025 at 12:02 AM
Moody threw a rave for herself in the backyard.
Reposted by Matt Manion
Watching a movie about a lonely heart who comes out of their shell to form a found family with an unlikely group of strangers. That’s right, Alien (1979) is a Christmas movie
December 26, 2025 at 3:29 AM
Watching a movie about a lonely heart who comes out of their shell to form a found family with an unlikely group of strangers. That’s right, Alien (1979) is a Christmas movie
Reposted by Matt Manion
GenAI is inevitable and will definitely be a major part of every art form from now on. Just like NFTs!
December 21, 2025 at 9:21 AM
GenAI is inevitable and will definitely be a major part of every art form from now on. Just like NFTs!
Reposted by Matt Manion
What bothers me more than anything about this is that many of the same people who correctly go, "This guy's a crank!" when he's talking about Tylenol causing autism or anti-vax stuff will sit there nodding along like, "Hey, if HHS said this, it must be legit!" when it involves trans care.
I’m at HHS headquarters where RFK Jr. is announcing new restrictions on gender-affirming care for minors by spouting pseudoscience and political misinformation that goes against every major medical association.
December 18, 2025 at 4:35 PM
What bothers me more than anything about this is that many of the same people who correctly go, "This guy's a crank!" when he's talking about Tylenol causing autism or anti-vax stuff will sit there nodding along like, "Hey, if HHS said this, it must be legit!" when it involves trans care.
Reposted by Matt Manion
Well, this is an utter disaster for science.
This gutting of peer review is very likely driven by Project 2025/OMB/Vought, very likely is about funding junk science, and very likely is coming for #NIH and biomedical research next.
🧪
This gutting of peer review is very likely driven by Project 2025/OMB/Vought, very likely is about funding junk science, and very likely is coming for #NIH and biomedical research next.
🧪
December 16, 2025 at 4:10 AM
Well, this is an utter disaster for science.
This gutting of peer review is very likely driven by Project 2025/OMB/Vought, very likely is about funding junk science, and very likely is coming for #NIH and biomedical research next.
🧪
This gutting of peer review is very likely driven by Project 2025/OMB/Vought, very likely is about funding junk science, and very likely is coming for #NIH and biomedical research next.
🧪
Reposted by Matt Manion
Re: the latest MetaAI noise, chip on my shoulder:
If it's the West Coast/In-A-Castle/etc circle of influencers:
* It's not "the TTRPG scene"
* It's not "big TTRPG people"
* [add all variations here]
It's not even generically "the D&D scene"! It's a very specific (if popular) influencer niche.
If it's the West Coast/In-A-Castle/etc circle of influencers:
* It's not "the TTRPG scene"
* It's not "big TTRPG people"
* [add all variations here]
It's not even generically "the D&D scene"! It's a very specific (if popular) influencer niche.
December 6, 2025 at 1:14 PM
Re: the latest MetaAI noise, chip on my shoulder:
If it's the West Coast/In-A-Castle/etc circle of influencers:
* It's not "the TTRPG scene"
* It's not "big TTRPG people"
* [add all variations here]
It's not even generically "the D&D scene"! It's a very specific (if popular) influencer niche.
If it's the West Coast/In-A-Castle/etc circle of influencers:
* It's not "the TTRPG scene"
* It's not "big TTRPG people"
* [add all variations here]
It's not even generically "the D&D scene"! It's a very specific (if popular) influencer niche.
Reposted by Matt Manion
Duolingo announced it was going “AI-first” just over six months ago. Since then its stock is down 64%.
December 5, 2025 at 4:43 PM
Duolingo announced it was going “AI-first” just over six months ago. Since then its stock is down 64%.