Meaghan Kennedy Ng
@mknbioinfgenome.bsky.social
Computational -omics, long non-coding RNA (lncRNA) lover, amateur photographer
Reposted by Meaghan Kennedy Ng
Just in time for #ASHG2025, a new FinnGen public data release is live!
This release features the first clinical laboratory value association results. Analyses cover 383 lab measurements (OMOPIDs) with data from ≥1,000 participants each.
Access the results here: www.finngen.fi/en/access_re...
This release features the first clinical laboratory value association results. Analyses cover 383 lab measurements (OMOPIDs) with data from ≥1,000 participants each.
Access the results here: www.finngen.fi/en/access_re...
October 14, 2025 at 2:17 PM
Just in time for #ASHG2025, a new FinnGen public data release is live!
This release features the first clinical laboratory value association results. Analyses cover 383 lab measurements (OMOPIDs) with data from ≥1,000 participants each.
Access the results here: www.finngen.fi/en/access_re...
This release features the first clinical laboratory value association results. Analyses cover 383 lab measurements (OMOPIDs) with data from ≥1,000 participants each.
Access the results here: www.finngen.fi/en/access_re...
Reposted by Meaghan Kennedy Ng
acmgscaler: an R package and Colab for standardized gene-level variant effect score calibration within the ACMG/AMP framework academic.oup.com/bioinformati... 🧬🖥️🧪 github.com/badonyi/acmg... #Rstats
October 14, 2025 at 3:55 PM
acmgscaler: an R package and Colab for standardized gene-level variant effect score calibration within the ACMG/AMP framework academic.oup.com/bioinformati... 🧬🖥️🧪 github.com/badonyi/acmg... #Rstats
Reposted by Meaghan Kennedy Ng
FIGHT FOR SCIENCE RALLY ✊🌏
⏰ WHEN: October 17th, 2025
📍WHERE: 200 Independence Ave SW, Washington DC!
RSVP to JOIN THE FIGHT IRL: zurl.co/LayiM ‼️
📲 Join us Virtually!: zurl.co/Um47l
⏰ WHEN: October 17th, 2025
📍WHERE: 200 Independence Ave SW, Washington DC!
RSVP to JOIN THE FIGHT IRL: zurl.co/LayiM ‼️
📲 Join us Virtually!: zurl.co/Um47l
October 8, 2025 at 1:36 PM
FIGHT FOR SCIENCE RALLY ✊🌏
⏰ WHEN: October 17th, 2025
📍WHERE: 200 Independence Ave SW, Washington DC!
RSVP to JOIN THE FIGHT IRL: zurl.co/LayiM ‼️
📲 Join us Virtually!: zurl.co/Um47l
⏰ WHEN: October 17th, 2025
📍WHERE: 200 Independence Ave SW, Washington DC!
RSVP to JOIN THE FIGHT IRL: zurl.co/LayiM ‼️
📲 Join us Virtually!: zurl.co/Um47l
Reposted by Meaghan Kennedy Ng
Delighted to have our preprint led by @lvchosen1.bsky.social
up: Genetic variation reveals a homeotic long noncoding RNA that modulates human hematopoietic stem cells
biorxiv.org/content/10.1...
🧵 below ...
up: Genetic variation reveals a homeotic long noncoding RNA that modulates human hematopoietic stem cells
biorxiv.org/content/10.1...
🧵 below ...
July 17, 2025 at 8:25 PM
Delighted to have our preprint led by @lvchosen1.bsky.social
up: Genetic variation reveals a homeotic long noncoding RNA that modulates human hematopoietic stem cells
biorxiv.org/content/10.1...
🧵 below ...
up: Genetic variation reveals a homeotic long noncoding RNA that modulates human hematopoietic stem cells
biorxiv.org/content/10.1...
🧵 below ...
Reposted by Meaghan Kennedy Ng
A key point here is the disconnect in awareness between researchers and everyone else (of course this is a feature, not a bug, for the government)
“[T]he effects from increases or decreases in funding can take upwards of seven years.”
“[T]he effects from increases or decreases in funding can take upwards of seven years.”
Proposed NIH cuts predicted to cause a drop in the US scientific workforce, to reduce support for public health, and to create gaps in scientific knowledge. Story by @aniloza.bsky.social
industryhttps://www.statnews.com/2025/07/28/nih-cuts-new-study-says-long-term-they-will-cost-more-than-saved/
industryhttps://www.statnews.com/2025/07/28/nih-cuts-new-study-says-long-term-they-will-cost-more-than-saved/
New analysis predicts sprawling effects of proposed NIH budget cuts
Initial analyses of the Trump administration’s proposed NIH cuts neglect key aspects of their long-term economic and health impact, study says.
www.statnews.com
July 29, 2025 at 2:23 AM
A key point here is the disconnect in awareness between researchers and everyone else (of course this is a feature, not a bug, for the government)
“[T]he effects from increases or decreases in funding can take upwards of seven years.”
“[T]he effects from increases or decreases in funding can take upwards of seven years.”
Reposted by Meaghan Kennedy Ng
An excellent systematic analysis of RBPs by @quaidmorris.bsky.social and colleagues (with a tiny contribution from us) #RNAsky #RNAbiology
New in @natbiotech.nature.com: a team led by scientists at MSK and University of Toronto have developed a new platform to facilitate the study of RNA-biding proteins (RBPs) across hundreds of species of plants, insects, and animals.
A resource of RNA-binding protein motifs across eukaryotes reveals evolutionary dynamics and gene-regulatory function - Nature Biotechnology
RNA-binding motifs in eukaryotic proteins are presented in a comprehensive resource.
www.nature.com
July 29, 2025 at 1:41 AM
An excellent systematic analysis of RBPs by @quaidmorris.bsky.social and colleagues (with a tiny contribution from us) #RNAsky #RNAbiology
Reposted by Meaghan Kennedy Ng
🚀 Today we're launching the 'Night Science Institute', a non-for-profit organization to lead a cultural shift in science! You may say we're dreamers 😉, but we think we're not the only ones. Perhaps today you will join us to make the Day Science and Night Science parts of the process live as one!
July 29, 2025 at 2:59 PM
🚀 Today we're launching the 'Night Science Institute', a non-for-profit organization to lead a cultural shift in science! You may say we're dreamers 😉, but we think we're not the only ones. Perhaps today you will join us to make the Day Science and Night Science parts of the process live as one!
Reposted by Meaghan Kennedy Ng
I am SO excited to receive this award and even more so to receive it along with @rogerslabucd.bsky.social!!!Congrats to all of the awardees and thank you for your support! We look forward to putting this award to work! 🙏🏾🎉
🌠 Announcing our latest awardees! 🤩 These talented scientists are uncovering how viruses infect cells, decoding cell behavior, and exploring the hidden biology in the ocean: bit.ly/HFAwardees.
Meet the awardees & hear about their bold projects from our #HFScouts 👇 /1
Meet the awardees & hear about their bold projects from our #HFScouts 👇 /1
June 17, 2025 at 4:55 PM
I am SO excited to receive this award and even more so to receive it along with @rogerslabucd.bsky.social!!!Congrats to all of the awardees and thank you for your support! We look forward to putting this award to work! 🙏🏾🎉
Reposted by Meaghan Kennedy Ng
Excited to share my first PhD paper in the @sbmontgom.bsky.social lab with @tamigj.bsky.social (www.biorxiv.org/content/10.1...)! Standard QTL methods treat each gene independently. But what if a single variant regulates multiple nearby genes at once - what we call “allelic proxitropy”? 🧵 ⬇️
June 8, 2025 at 5:39 PM
Excited to share my first PhD paper in the @sbmontgom.bsky.social lab with @tamigj.bsky.social (www.biorxiv.org/content/10.1...)! Standard QTL methods treat each gene independently. But what if a single variant regulates multiple nearby genes at once - what we call “allelic proxitropy”? 🧵 ⬇️
Reposted by Meaghan Kennedy Ng
"I am so scared about doing this, but I am trying to be brave for my kids because it's only going to get harder to speak up....Maybe I'm putting my kids at risk by doing this. And I'm doing it anyway because I couldn't live with myself otherwise."
apnews.com/article/nih-...
apnews.com/article/nih-...
NIH scientists publish declaration criticizing Trump's deep cuts in public health research
President Donald Trump’s National Institutes of Health director says some employees’ critical letter to him has “fundamental misconceptions about the policy directions the NIH has taken.”
apnews.com
June 9, 2025 at 6:43 PM
"I am so scared about doing this, but I am trying to be brave for my kids because it's only going to get harder to speak up....Maybe I'm putting my kids at risk by doing this. And I'm doing it anyway because I couldn't live with myself otherwise."
apnews.com/article/nih-...
apnews.com/article/nih-...
Reposted by Meaghan Kennedy Ng
My personal takeaways from Dorrestein's talk on microbiome-derives molecules and big data metabolomics:
- should have taken biochem
- I need to dig more into metabolomics
- SCFAs are so important y'all. Eat your fiber
- also bile acids evidently
- dietary assessments suck 1/2
#HCMPHSymposium
- should have taken biochem
- I need to dig more into metabolomics
- SCFAs are so important y'all. Eat your fiber
- also bile acids evidently
- dietary assessments suck 1/2
#HCMPHSymposium
May 19, 2025 at 2:01 PM
My personal takeaways from Dorrestein's talk on microbiome-derives molecules and big data metabolomics:
- should have taken biochem
- I need to dig more into metabolomics
- SCFAs are so important y'all. Eat your fiber
- also bile acids evidently
- dietary assessments suck 1/2
#HCMPHSymposium
- should have taken biochem
- I need to dig more into metabolomics
- SCFAs are so important y'all. Eat your fiber
- also bile acids evidently
- dietary assessments suck 1/2
#HCMPHSymposium
Reposted by Meaghan Kennedy Ng
👀 You know who has the chops to give some EXCELLENT #SummerFightForScience Teach Ins?
🧪 👩🏫 Middle and High School science teachers 👀
#StandUpForScience
🧪 👩🏫 Middle and High School science teachers 👀
#StandUpForScience
Our goal is to have 1000 SUFS Teach Ins across the US, by 9/30.
*GASP* 😮
We know, it's a big goal.
If you've received tax dollars for your science, you have a responsibility to inform *your* community what is at stake: public health, the economy, innovation, and America's global leadership.
*GASP* 😮
We know, it's a big goal.
If you've received tax dollars for your science, you have a responsibility to inform *your* community what is at stake: public health, the economy, innovation, and America's global leadership.
May 19, 2025 at 2:48 PM
👀 You know who has the chops to give some EXCELLENT #SummerFightForScience Teach Ins?
🧪 👩🏫 Middle and High School science teachers 👀
#StandUpForScience
🧪 👩🏫 Middle and High School science teachers 👀
#StandUpForScience
Reposted by Meaghan Kennedy Ng
New preprint of @trono-lab.bsky.social and my PhD work!
By modulating SWI/SNF remodeling at ancient transposable elements - LINE/L2s and SINE/MIRs, a "noncanonical" KZFP called ZNF436 protects cardiomyocytes from losing their identity.
🫀heartbeat on 🔁 repeat
www.biorxiv.org/content/10.1... #TEsky
By modulating SWI/SNF remodeling at ancient transposable elements - LINE/L2s and SINE/MIRs, a "noncanonical" KZFP called ZNF436 protects cardiomyocytes from losing their identity.
🫀heartbeat on 🔁 repeat
www.biorxiv.org/content/10.1... #TEsky
May 19, 2025 at 2:01 PM
New preprint of @trono-lab.bsky.social and my PhD work!
By modulating SWI/SNF remodeling at ancient transposable elements - LINE/L2s and SINE/MIRs, a "noncanonical" KZFP called ZNF436 protects cardiomyocytes from losing their identity.
🫀heartbeat on 🔁 repeat
www.biorxiv.org/content/10.1... #TEsky
By modulating SWI/SNF remodeling at ancient transposable elements - LINE/L2s and SINE/MIRs, a "noncanonical" KZFP called ZNF436 protects cardiomyocytes from losing their identity.
🫀heartbeat on 🔁 repeat
www.biorxiv.org/content/10.1... #TEsky
Reposted by Meaghan Kennedy Ng
🚨SCIENCE UNDER SIEGE: TRUMP’S FIRST 100 DAYS 🚨
In his first 100 days, Trump has declared war on science—slashing budgets, censoring facts, and meddling in research. From climate to cancer care, real lives are at risk.
Here’s a thread on Trump’s assault on science so far—and why it matters: (🧵)
In his first 100 days, Trump has declared war on science—slashing budgets, censoring facts, and meddling in research. From climate to cancer care, real lives are at risk.
Here’s a thread on Trump’s assault on science so far—and why it matters: (🧵)
April 29, 2025 at 9:18 PM
🚨SCIENCE UNDER SIEGE: TRUMP’S FIRST 100 DAYS 🚨
In his first 100 days, Trump has declared war on science—slashing budgets, censoring facts, and meddling in research. From climate to cancer care, real lives are at risk.
Here’s a thread on Trump’s assault on science so far—and why it matters: (🧵)
In his first 100 days, Trump has declared war on science—slashing budgets, censoring facts, and meddling in research. From climate to cancer care, real lives are at risk.
Here’s a thread on Trump’s assault on science so far—and why it matters: (🧵)
Reposted by Meaghan Kennedy Ng
Kennedy wants to track people with Autism.
This is a violation of HIPAA.
This is a violation of HIPAA.
RFK Jr. Set to Launch Disease Registry Tracking Autistic People
And he’s using private medical records to make it happen.
newrepublic.com
April 22, 2025 at 6:24 PM
Kennedy wants to track people with Autism.
This is a violation of HIPAA.
This is a violation of HIPAA.
Reposted by Meaghan Kennedy Ng
The US government has dismantled all covid related tracking & reporting despite people dying and becoming disabled every day… Yet they’re establishing a registry to track autism cases and plan to access people’s private medical data.
Autism doesn’t kill. It’s not contagious. This is eugenics
Autism doesn’t kill. It’s not contagious. This is eugenics
April 23, 2025 at 9:06 PM
The US government has dismantled all covid related tracking & reporting despite people dying and becoming disabled every day… Yet they’re establishing a registry to track autism cases and plan to access people’s private medical data.
Autism doesn’t kill. It’s not contagious. This is eugenics
Autism doesn’t kill. It’s not contagious. This is eugenics
Reposted by Meaghan Kennedy Ng
What Republicans are fighting is literally visual symptoms of disability. Being so different, you're difficult and not helpful to the party. That's eugenics. Autism you can hide is fine. Disability you can't needs to be eradicated.
April 23, 2025 at 1:24 AM
What Republicans are fighting is literally visual symptoms of disability. Being so different, you're difficult and not helpful to the party. That's eugenics. Autism you can hide is fine. Disability you can't needs to be eradicated.
Reposted by Meaghan Kennedy Ng
The reason autism has such a stigma in the first place is because so many people who have it are able to mask well enough to pass or are just considered quirky by ignorant friends and family. People with nonverbal or profound autism can't and historically are treated as burdens rather than people.
April 23, 2025 at 1:20 AM
The reason autism has such a stigma in the first place is because so many people who have it are able to mask well enough to pass or are just considered quirky by ignorant friends and family. People with nonverbal or profound autism can't and historically are treated as burdens rather than people.
Reposted by Meaghan Kennedy Ng
RFK's sinister autism registry reeks of eugenics and must be fought. That said? Autism is one of the most undiagnosed conditions there is. Only 1 in 4 people who have it are officially diagnosed, and testing is expensive. This cartoonisly evil plan to get rid of autism is dumb on a most basic level.
April 23, 2025 at 1:15 AM
RFK's sinister autism registry reeks of eugenics and must be fought. That said? Autism is one of the most undiagnosed conditions there is. Only 1 in 4 people who have it are officially diagnosed, and testing is expensive. This cartoonisly evil plan to get rid of autism is dumb on a most basic level.
Reposted by Meaghan Kennedy Ng
my endorsement for any democratic presidential candidate who promises to send the entire DOGE team to prison
This is insane and everyone involved needs to be sued into oblivion and then go directly to jail
April 24, 2025 at 7:37 PM
my endorsement for any democratic presidential candidate who promises to send the entire DOGE team to prison
Reposted by Meaghan Kennedy Ng
I don't get why none of the foundations I've written grants for in the last 2 years want to fund me. I try so hard. I get good results. I get a lot done for not a lot of money. I integrate science & art, am good at community organizing, & get science into places where there currently isn't much.
April 24, 2025 at 7:52 PM
I don't get why none of the foundations I've written grants for in the last 2 years want to fund me. I try so hard. I get good results. I get a lot done for not a lot of money. I integrate science & art, am good at community organizing, & get science into places where there currently isn't much.
Reposted by Meaghan Kennedy Ng
Vance and the pope, Hegseth's signal groups, Rubio unraveling the state department, RFK Jr.'s antics—it's a lot.
Don't lose sight of the way they are destroying due process.
278 US "deportees" are still in CECOT. They're stonewalling on Abrego Garcia. Others have plain disappeared.
Gift link.
Don't lose sight of the way they are destroying due process.
278 US "deportees" are still in CECOT. They're stonewalling on Abrego Garcia. Others have plain disappeared.
Gift link.
Venezuelan Immigrant Deported by Trump Administration Has Disappeared (Gift Article)
The Venezuelan man does not appear on a list of people sent to a prison in El Salvador, and his family and friends have no idea of his whereabouts.
www.nytimes.com
April 22, 2025 at 6:02 PM
Vance and the pope, Hegseth's signal groups, Rubio unraveling the state department, RFK Jr.'s antics—it's a lot.
Don't lose sight of the way they are destroying due process.
278 US "deportees" are still in CECOT. They're stonewalling on Abrego Garcia. Others have plain disappeared.
Gift link.
Don't lose sight of the way they are destroying due process.
278 US "deportees" are still in CECOT. They're stonewalling on Abrego Garcia. Others have plain disappeared.
Gift link.
Reposted by Meaghan Kennedy Ng
What a great initiative. It's so important to hear the stories of silenced scientists. 🧪 ⚛️ 👩🔬
Portraits of dismissed scientists personalize US government cuts to science
A hurricane researcher. An invasive-insect entomologist. An e-cigarette toxicologist. A biomedical librarian. Those are some of the people included in Silenced Science Stories, a visual storytelling p...
pubs.aip.org
April 21, 2025 at 4:12 PM
What a great initiative. It's so important to hear the stories of silenced scientists. 🧪 ⚛️ 👩🔬
Reposted by Meaghan Kennedy Ng
A Border Patrol official arrested a 19 yo citizen from Albuquerque in Arizona who didn’t have ID on him, claimed he ‘admitted’ to illegally crossing the border, abducted + ICE imprisoned him for 10 days, and would have deported him to Mexico if his family hadn’t tracked him down and provided his ID.
April 20, 2025 at 3:41 PM
A Border Patrol official arrested a 19 yo citizen from Albuquerque in Arizona who didn’t have ID on him, claimed he ‘admitted’ to illegally crossing the border, abducted + ICE imprisoned him for 10 days, and would have deported him to Mexico if his family hadn’t tracked him down and provided his ID.