An argument for the pit
@jeblucas.bsky.social
Gen X Dad // Data Science and Analytics // Ultimate // Recreational Math // Movies // DemSoc // Games (board/card/video) // Puzzles// Post-retirement Peaker (in about 15 years)
Pinned
I am a technically savvy guy with knowledge on science, tech, math type stuff. If you need or want something explained to you at a level you are comfortable with; no judgement; let me know here or in DMs.
Breaking the NONMEM lock would be a huge deal. I’ll look into this one.
nlmixr2 is becoming an R Consortium Working Group!
Open-source NLME modeling in R that can compete with commercial pharmacometric tools and support regulatory submissions.
More: r-consortium.org/posts/nlmixr...
#RStats #pharma
Open-source NLME modeling in R that can compete with commercial pharmacometric tools and support regulatory submissions.
More: r-consortium.org/posts/nlmixr...
#RStats #pharma
November 27, 2025 at 5:41 AM
Breaking the NONMEM lock would be a huge deal. I’ll look into this one.
Reposted by An argument for the pit
"I say we take off and nuke the site from orbit. It's the only way to be sure."
November 27, 2025 at 2:30 AM
"I say we take off and nuke the site from orbit. It's the only way to be sure."
Reposted by An argument for the pit
People will die, and are currently dying, because RFK was granted one of the most powerful megaphones in the country. Two people who could have thrown barriers in front of his climb decided not to; there's a sex scandal here but it is not the biggest scandal.
November 26, 2025 at 11:30 PM
People will die, and are currently dying, because RFK was granted one of the most powerful megaphones in the country. Two people who could have thrown barriers in front of his climb decided not to; there's a sex scandal here but it is not the biggest scandal.
Reposted by An argument for the pit
The Keebler Elves are billionaires now, and as part of the President's Advisory Council they've said some alarming things about the connection between Pepperidge Farms and autism.
November 27, 2025 at 12:27 AM
The Keebler Elves are billionaires now, and as part of the President's Advisory Council they've said some alarming things about the connection between Pepperidge Farms and autism.
Reposted by An argument for the pit
I had a great time with Steven (PSYCHO GOREMAN) Kostanski's reimagining of DEATHSTALKER, an absurdly awesome practical effects fantasia and excellent starring vehicle for Daniel Bernhardt (seen here with swamp monster friend).
Deathstalker (2025) | VERN'S REVIEWS on the FILMS of CINEMA
I was a child of the 1980s, but not of HBO or Showtime. That’s probly why I never saw DEATHSTALKER (1983) until last week. Still, I knew the idea of
outlawvern.com
November 27, 2025 at 12:11 AM
I had a great time with Steven (PSYCHO GOREMAN) Kostanski's reimagining of DEATHSTALKER, an absurdly awesome practical effects fantasia and excellent starring vehicle for Daniel Bernhardt (seen here with swamp monster friend).
Reposted by An argument for the pit
But the development history of #Barbarians is much longer than that. #msdos is the third platform for which I've released the game. The original version was developed for the once-popular range of pocket computers from #Psion. damian.cyningstan.org.uk/downloads/21... #gamedev
November 14, 2025 at 1:32 PM
But the development history of #Barbarians is much longer than that. #msdos is the third platform for which I've released the game. The original version was developed for the once-popular range of pocket computers from #Psion. damian.cyningstan.org.uk/downloads/21... #gamedev
Reposted by An argument for the pit
I'm looking for our network password to set up the cat's shitter and I'm crying laughing.
God I needed this today.
God I needed this today.
November 26, 2025 at 11:22 PM
I'm looking for our network password to set up the cat's shitter and I'm crying laughing.
God I needed this today.
God I needed this today.
Reposted by An argument for the pit
ZIWE: Which is your favorite feature of ChatGPT - the people killing themselves or the plagiarism?
ALTMAN: I, uh, I, well, I wouldn’t,
ZIWE: How much money do you have in your wallet?
ALTMAN: I, uh, I, well, I wouldn’t,
ZIWE: How much money do you have in your wallet?
November 26, 2025 at 9:50 PM
ZIWE: Which is your favorite feature of ChatGPT - the people killing themselves or the plagiarism?
ALTMAN: I, uh, I, well, I wouldn’t,
ZIWE: How much money do you have in your wallet?
ALTMAN: I, uh, I, well, I wouldn’t,
ZIWE: How much money do you have in your wallet?
I only made half a pot of mashed potatoes
November 26, 2025 at 7:17 PM
I only made half a pot of mashed potatoes
Reposted by An argument for the pit
Bunch of sad men built the world's most expensive and racist Magic Eight Ball and then tried to convince everyone else that it was absolutely essential that they treat it like their teacher and their lover.
November 26, 2025 at 6:47 PM
Bunch of sad men built the world's most expensive and racist Magic Eight Ball and then tried to convince everyone else that it was absolutely essential that they treat it like their teacher and their lover.
Good conversation enders for Thursday:
When Uncle Blort quote some wacked-out Fox News (or worse, come on Blort) interpretation of some recent event:
“What an interesting thing to say.”
When you espouse your (correct) leftist socialist views and everyone goes apeshit:
“We don’t have to agree.”
When Uncle Blort quote some wacked-out Fox News (or worse, come on Blort) interpretation of some recent event:
“What an interesting thing to say.”
When you espouse your (correct) leftist socialist views and everyone goes apeshit:
“We don’t have to agree.”
November 26, 2025 at 6:52 PM
Good conversation enders for Thursday:
When Uncle Blort quote some wacked-out Fox News (or worse, come on Blort) interpretation of some recent event:
“What an interesting thing to say.”
When you espouse your (correct) leftist socialist views and everyone goes apeshit:
“We don’t have to agree.”
When Uncle Blort quote some wacked-out Fox News (or worse, come on Blort) interpretation of some recent event:
“What an interesting thing to say.”
When you espouse your (correct) leftist socialist views and everyone goes apeshit:
“We don’t have to agree.”
Reposted by An argument for the pit
Meanwhile, on Reddit: "would food made by a Star Trek food replicator be kosher?" 😁 🖖
From the Jewish community on Reddit
Explore this post and more from the Jewish community
www.reddit.com
November 26, 2025 at 6:19 PM
Meanwhile, on Reddit: "would food made by a Star Trek food replicator be kosher?" 😁 🖖
Reposted by An argument for the pit
Good morning to Brazilian reporter Manuela Borges, who’s been waiting eleven years for this petty moment. ❤️ 🇧🇷
November 26, 2025 at 1:04 PM
Good morning to Brazilian reporter Manuela Borges, who’s been waiting eleven years for this petty moment. ❤️ 🇧🇷
Reposted by An argument for the pit
Putting in a vote to not share shit I can’t see. I don’t have TikTok, bruh. You want me to see that cool video, but they want me to download the app. Figure your shit out.
If you are thinking, “oh well maybe get TikTok if you want to see it” and buddy TIKTOK IS WHERE YOU SHOULD SHARE THAT.
If you are thinking, “oh well maybe get TikTok if you want to see it” and buddy TIKTOK IS WHERE YOU SHOULD SHARE THAT.
November 26, 2025 at 1:54 AM
Putting in a vote to not share shit I can’t see. I don’t have TikTok, bruh. You want me to see that cool video, but they want me to download the app. Figure your shit out.
If you are thinking, “oh well maybe get TikTok if you want to see it” and buddy TIKTOK IS WHERE YOU SHOULD SHARE THAT.
If you are thinking, “oh well maybe get TikTok if you want to see it” and buddy TIKTOK IS WHERE YOU SHOULD SHARE THAT.
Reposted by An argument for the pit
well okay then, P.F. Chang’s!!! 😳
November 21, 2025 at 2:52 AM
well okay then, P.F. Chang’s!!! 😳
Reposted by An argument for the pit
"big fan, love to rip you off!"
November 25, 2025 at 11:34 PM
"big fan, love to rip you off!"
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Question about the dissent by (the far-right) Justice Ziegler: Does this quote actually appear in Moore v. Harper? Did Moore say that state courts' role in congressional redistricting is "exceedingly limited"? I don't think it did! vhdshf2oms2wcnsvk7sdv3so.blob.core.windows.net/thearp-media...
November 25, 2025 at 9:11 PM
Question about the dissent by (the far-right) Justice Ziegler: Does this quote actually appear in Moore v. Harper? Did Moore say that state courts' role in congressional redistricting is "exceedingly limited"? I don't think it did! vhdshf2oms2wcnsvk7sdv3so.blob.core.windows.net/thearp-media...
Reposted by An argument for the pit
Reposted by An argument for the pit
Amazing to learn that Isaac Chotiner can apparently just come for you in your replies. Like suddenly realizing you're swimming in open ocean
November 25, 2025 at 3:48 PM
Amazing to learn that Isaac Chotiner can apparently just come for you in your replies. Like suddenly realizing you're swimming in open ocean
Reposted by An argument for the pit
Got pretty excited when I overheard my wife tell my son to "Convert to radical form" but it turns out they were just doing math?
November 25, 2025 at 2:51 PM
Got pretty excited when I overheard my wife tell my son to "Convert to radical form" but it turns out they were just doing math?
Reposted by An argument for the pit
the goat-est edit ever made if we're being real.
barry lyndon x 21 savage by @/flanthippe on twitter.
barry lyndon x 21 savage by @/flanthippe on twitter.
November 15, 2024 at 2:04 PM
the goat-est edit ever made if we're being real.
barry lyndon x 21 savage by @/flanthippe on twitter.
barry lyndon x 21 savage by @/flanthippe on twitter.
Trying to wrap my head around a twin pack of KEM cards is >$75? Up to like $95? For real?
November 25, 2025 at 2:36 PM
Trying to wrap my head around a twin pack of KEM cards is >$75? Up to like $95? For real?
Reposted by An argument for the pit
Reposted by An argument for the pit
My father’s youngest sister, who was only five years older than me moved in with us in 1980, and she and her friends had “sacred” songs which they’d go dead silent when they came on the radio.
“Walk on the Wild Side” was one of them.
“Walk on the Wild Side” was one of them.
17) I’ve said this before, but: somehow, i knew who Gary Gygax was before I knew who Lou Reed was
November 25, 2025 at 2:24 PM
My father’s youngest sister, who was only five years older than me moved in with us in 1980, and she and her friends had “sacred” songs which they’d go dead silent when they came on the radio.
“Walk on the Wild Side” was one of them.
“Walk on the Wild Side” was one of them.