Author | Lightnews

Reposted by Kate Caturjelly

Crimson @crimsonruari.bsky.social · 5h

Seriously, Nebula costs almost nothing and just getting a handful of video makers I like on the service is worth it. There’s a bunch of stuff on there I haven’t explored but friend says is also good. So… yeah. Not to have more streaming services but Nebula is pretty good.

Ray Delahanty | CityNerd @nerd4cities.bsky.social · 5h

If you aren’t already on Nebula, this is a cool opportunity to gorge yourself. Link in reply!

Nebula @nebula.tv · 11h

Three-day free trials now available. Clear your weekend.

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Waldo Jaquith @waldo.net · 4h

Reminder: It benefits nobody in a way to list sex assigned at birth on passports, there is no requirement to include it, this is just about punishing trans etc. Americans.

Chris Geidner @chrisgeidner.bsky.social · 6h

BREAKING: The Supreme Court will allow the Trump administration to enforce its anti-trans and anti-nonbinary passport policy during litigation.

The unsigned, four-paragraph order effectively reverses two lower-court decisions. The Democratic appointees dissent.

More to come: www.lawdork.com

SUPREME COURT OF THE UNITED STATES
No. 25A319
DONALD J. TRUMP, PRESIDENT OF THE UNITED
STATES, ET AL. v. ASHTON ORR, ET AL.
ON APPLICATION FOR STAY
[November 6, 2025]
This case concerns an Executive Branch policy requiring
all new passports to display an individual’s biological sex at
birth. The United States District Court for the District of
Massachusetts preliminarily enjoined the Government
from enforcing the policy, and the First Circuit declined to
stay the injunction pending appeal. The Government then
filed this stay application. Applying our familiar stay fac-
tors at this preliminary stage, we grant the application.

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Chise @sailorrooscout.bsky.social · 1d

Researchers envision their vaccine being used as both a treatment and a preventive, and as an approach to treating multiple cancer types.
• www.umass.edu/news/article...

The study has been published in Cell Reports Medicine. YES, it is PEER-REVIEWED.
• www.cell.com/cell-reports...

🧪🧵⬇️

HIGHLIGHTS
• Lipid NPs carrying STING and TLR4 agonists promote synergistic type I interferons
• NPs drain efficiently to lymph nodes and increase polyfunctional T and B cells
• NPs improve tumor-free outcomes with memory against multiple aggressive tumor models
SUMMARY
We report on the utility of a "super-adjuvant" nanoparticle (NP) system as a modular, customizable platform for next-generation cancer vaccination. Using nanomaterials engineering technology, we aim to harness not only the effective adjuvanticity of whole-pathogen vaccines, but also the safety of subunit vaccines.
Our lipid-based NP platform co-encapsulates agonists of the stimulator of interferon genes (STING) and Toll-like receptor 4 (TLR4) pathways to promote synergistic production of type I interferons and other
proinflammatory cytokines in innate antigen-presenting dendritic cells and macrophages.
Compared to empty NPs and free agonists, dual-adjuvant NPs administered with antigenic peptides or tumor cell lysate promote increased antigen processing and presentation, drain efficiently to nearby lymph nodes, increase polyfunctional tumor-specific T and B cells, and improve tumor-free outcomes upon vaccination and subsequent challenge with multiple aggressive tumor cells.

Graphical Abstract

The vaccine combines two immune-stimulating molecules (adjuvants) in a tiny lipid nanoparticle that enhances both innate and adaptive immune responses. The innate immune system acts as the body’s first line of defense, responding quickly and non-specifically to invaders using cells that release inflammatory signals. The adaptive immune system takes longer to activate but provides a targeted, long-lasting response, training T-cells and B- cells to recognize and remember specific threats. Together, they form a coordinated defense: the innate system alerts and activates the adaptive system, which then delivers precise and durable immunity.

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Chise @sailorrooscout.bsky.social · 1d

GOOD NEWS! Researchers have developed a cancer vaccine that has shown STUNNING results, PREVENTING up to 88% of MULTIPLE aggressive cancers by harnessing dual-pathway nanoparticles that train the immune system to recognize and destroy tumor cells. In some cases, it COMPLETELY prevented metastasis.

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Skeletal Viking Amy @lasrina.bsky.social · 1d

Reposting because, and I say this with love, some of you are going to see this and go “oh shit, I need to check my bottle” and then immediately forget about it so if this could affect you, go check right now before you even scroll to the next post, I mean it.

SPOOKY Mistress Usili (Sage) 🏳️‍⚧️ @usili.bsky.social · 1d

As a headsup for anyone on Vyvanse, you should go check your lot numbers.

www.health.com/adhd-medicat...

FDA Announces Nationwide Recall of ADHD Medication—Check Your Cabinets Now

Sun Pharmaceutical Industries has recalled several lots lisdexamfetamine dimesylate capsules, a generic form of Vyvanse, after testing found they failed to dissolve properly.

www.health.com

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Faine Greenwood @faineg.bsky.social · 2d

this marketing decision from huge corporations going hard at LLM products has just been outrageously corrosive to public discussion, and i'm going to be angry about it forever

Fletcher Thompson (🔬+🐝) @fletch.online · 3d

My biggest grumble is how everything else just gets rolled up under this huge ‘AI’ marketing banner. Machine learning? Fuzzy logic? Split-span decision trees? Computer vision, 2D convolution mapping and tracking? All AI now. Boo!

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Catsuka @catsuka.bsky.social · 2d

From "Baahubali - The Eternal War - Part 1" (Indian movie, 2027).
Co-produced with French animation studio Alcyde, and several "Arcane" artists.
Directed by Ishan Shukla ("Star Wars Visions" S2, "Schirkoa" Indian-French movie...).
Full trailer >> www.youtube.com/watch?v=RdUP...

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Better Things Are Possible @internethippo.bsky.social · 2d

Incredibly funny to watch the right wing going Oh so just because I love money and hate poor people I'm a bad Christian according to "the pope"???

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Trans Ferdinand: Robot Princess @emdashreed.bsky.social · 2d

good morning,

a crab is crawling on the sand on a beach .

Alt: Crab rave!

media.tenor.com

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Matt Zoller Seitz @mattzollerseitz.bsky.social · 3d

This magazine just fired all of their politics staffers

Teen Vogue @teenvogue.com · Aug 7

We are honored to receive the @rooseveltinstitute.org's 2025 Four Freedoms Award for Freedom of Speech and Expression, and to be among a stellar class of laureates including @wck.org, @cvt.org, and more. Details: tnvge.co/ZMIUg7v

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Allegra Kirkland @allegrak.bsky.social · 3d

Teen Vogue was one of the only outlets that took young people seriously as political actors and covered how they're organizing, voting, and being impacted by state + national legislation.

It was a launching pad for so many great young journalists

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Phineas @phineas.bsky.social · 3d

New awareness campaign

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Kara Jorgensen @authorkaraj.bsky.social · 3d

I really love this Vincent Van Gogh quote:

"To do good work one must eat well, be well housed, have one's fling from time to time, smoke one's pipe, and drink one's coffee in peace."

No romanticizing the starving artist. Van Gogh said UBI all the way.

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Kate Caturjelly @firekesti.net · 3d

this thread brought to you by Too Much Sake and A Hundred Kanji Reviews

Kate Caturjelly @firekesti.net · 3d

oh and the reading is が ga, from extravaGAnza ofc

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Kate Caturjelly @firekesti.net · 3d

warning for all etymology nerds: japanese has a whole other thing going on so good luck you're gonna get way too into it (good thing)

Kate Caturjelly @firekesti.net · 3d

what cool kanji have I learned recently. ah. 賀 which means congratulations, and contains the radicals for 力 power、口 mouth､ and 貝 shellfish, and which I will remember via the sushi extravaganza I commit my mouth to power through every birthday (congrats)

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lauren @lauren.rotatingsandwiches.com · 4d

it's so crazy we don't have a coke freestyle type of machine but for chip flavors. in some ways we're still basically living in the stone age

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Kate Caturjelly @firekesti.net · 3d

Mr Human RIGHTS Protector and Ms Human RIGHTS Advancer/Progressor, ナイフ

Mondo Mascots @mondomascots.bsky.social · 4d

Japan’s human rights mascots are Jin-KEN-Mamoru-kun and Jin-KEN-Ayumi-chan.

A pair of mascots with black bangs and with “KEN” written on their chests stand in a park.

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Mekka Okereke @mekka.mekka-tech.com · 4d

"On two occasions I have been asked, 'Pray, Mr. Babbage, if you put into the machine wrong figures, will the right answers come out?'... I am not able rightly to apprehend the kind of confusion of ideas that could provoke such a question."

Charles Babbage, inventor of the mechanical computer, 1864