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Hanbin Lee

@epigenci.bsky.social

700 followers 2.1K following 500 posts

PhD Student at UMich Statistics. The account mostly trashes about urban planning and infrastructure. Probability, Statistics, and Evolutionary Biology. https://hanbin973.github.io

hanbin973.github.io

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Hanbin Lee @epigenci.bsky.social · Jul 19

My talk from this year's probgen is finally out.

Where do linear mixed models and random effects come from?

They emerge from *mutations* on Ancestral Recombination Graphs.

bioRxiv Genomics @biorxiv-genomic.bsky.social · Jul 18

Modelling complex traits with ancestral recombination graphs https://www.biorxiv.org/content/10.1101/2025.07.14.664631v1

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Hanbin Lee @epigenci.bsky.social · 2h

I think we don't have the same jargon in Korea.

Hanbin Lee @epigenci.bsky.social · 2h

Where did the meaning of tidal waves as a metaphor originate from? I wonder in any parts of Europe there's a huge tidal difference?

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Reposted by Hanbin Lee

Rebecca Sear @rebeccasear.bsky.social · 11h

“the manosphere generates its own untested and speculative evolutionary hypotheses, or “just-so stories”, about men, women, and society…

..we reflect on implications for evolutionary scholars and for the field as a whole, in terms of ethics and public image”

www.cambridge.org/core/journal...

A Hundred and Two Just-So Stories: Exploring the Lay Evolutionary Hypotheses of the Manosphere | Evolutionary Human Sciences | Cambridge Core

A Hundred and Two Just-So Stories: Exploring the Lay Evolutionary Hypotheses of the Manosphere

www.cambridge.org

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Hanbin Lee @epigenci.bsky.social · 1d

I think "have legacy admission" and "submit to fed" will have a pretty high correlation.

Hanbin Lee @epigenci.bsky.social · 1d

academic.oup.com/genetics/adv...

I recently realized that I have overlooked mutational models. Especially, how it related to our ability to observe them.

Mutation-selection-drift balance models of complex diseases

Abstract. Genetic variation that influences complex disease susceptibility is introduced into the population by mutation and removed by natural selection a

academic.oup.com

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Hanbin Lee @epigenci.bsky.social · 1d

저거 마음대로 도시 이름 바꿔 부르는 영어권 화자들이 문제죠 ㅋㅋ

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Hanbin Lee @epigenci.bsky.social · 1d

I've been regretting about the exact same thing for the past 15+ years in exam seasons and I'm now 30 lol

Reposted by Hanbin Lee

CalMatters @calmatters.org · 2d

After weeks of waiting, California's governor signed a bill that will allow mid-rise apartment buildings near major transit stops in California's biggest metro areas. https://cal.news/4n3hzge

📝 @frombenc.bsky.social
📸 Ray Chavez

Passengers look on as a BART train didn’t stop at the Rockridge BART station due to a systemwide closure that affected all BART stations, in Oakland on March 9, 2025. Photo by Ray Chavez, Bay Area News Group

Hed: Breaking: Gov. Newsom signs massive California housing overhaul

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Reposted by Hanbin Lee

Pausal Zivference @pausalz.bsky.social · 3d

For years I had trouble following some of the discussion about confidence bands, but at ACIC this year @noahgreifer.bsky.social pointed me to a helpful paper

So you don't have to be as perplexed as I once was, we have a new pre-print introducing the key ideas
arxiv.org/abs/2510.07076

Confidence Regions for Multiple Outcomes, Effect Modifiers, and Other Multiple Comparisons

In epidemiology, some have argued that multiple comparison corrections are not necessary as there is rarely interest in the universal null hypothesis. From a parameter estimation perspective, epidemio...

arxiv.org

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Reposted by Hanbin Lee

Quinta Jurecic @qjurecic.bsky.social · 3d

he's going to come after you either way, so you might as well act with integrity

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Reposted by Hanbin Lee

Rebecca R Helm @rebeccarhelm.bsky.social · 3d

Many sea stars begin life as young fairy-like creature (called a brachiolaria) that float through the open ocean. Eventually, a small star forms within them (here in yellow). The fairy-like brachiolaria sinks under the star’s weight, and the star pops out!
🎥@the_story_of_a_biologist (on Insta)

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Hanbin Lee @epigenci.bsky.social · 3d

Is evopsych even popular anymore? I continue to keep my view that evopsych is the Holy Roman Empire, like once Voltaire said, neither is it Evo nor Psych. A typical bad faith attitude that adding some natural science flavor automatically upgrades the rigor.

Hanbin Lee @epigenci.bsky.social · 3d

Our paper (Brieuc Lehmann is the first author) is now online in Genetics.

academic.oup.com/genetics/adv...

On ARGs, pedigrees, and genetic relatedness matrices

Abstract. Genetic relatedness is a central concept in genetics, underpinning studies of population and quantitative genetics in human, animal, and plant se

academic.oup.com

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Reposted by Hanbin Lee

crustyone2.bsky.social @crustyone2.bsky.social · 4d

Was she Canadian.

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Hanbin Lee @epigenci.bsky.social · 3d

www.jura.bio/blog/leavs

Reposted by Hanbin Lee

April Wei @aprilwei.bsky.social · 4d

Method works from simple and complex scenarios in jointly estimating epoch time, population size, migration rate (symmetric or asymmetric), growth rate, and admixture proportion. Software integrated with msprime, demes, tsinfer/tsdate, relate, and singer. github.com/aprilweilab/...

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Reposted by Hanbin Lee

April Wei @aprilwei.bsky.social · 4d

Excited to preprint our latest work (w/ Drew DeHaas, Zhibai Jia, Leo Speidel) on using ARGs for demographic inference. w/ applications using data from 1000 Genomes Project. www.biorxiv.org/content/10.1...

Inference of complex demographic history using composite likelihood based on whole-genome genealogies

Accurate parametric inference on complex demographic models is a continuing challenge in population genetics. Ancestral recombination graphs (ARGs) provide richer information than simple population ge...

www.biorxiv.org

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Hanbin Lee @epigenci.bsky.social · 6d

github.com/jax-ml/jax/i... lol

JAX and TORCH · Issue #18032 · jax-ml/jax

Description When I only pip the latesd jax with cuda(pip install --upgrade "jax[cuda12_pip]" -f https://storage.googleapis.com/jax-releases/jax_cuda_releases.html), I can use the jax with gpu.But w...

github.com

Reposted by Hanbin Lee

Janne Pott @pottj.bsky.social · 6d

📣Preprint alert - a tricky one, as there are no significant results (and we all know null-results are hard to publish)
Do PCSK9 levels affect survival in breast cancer patients?
We tried to replicate findings in cell lines and mouse model using 3 Mendelian Randomization approaches, but failed.

medRxivpreprint @medrxivpreprint.bsky.social · 6d

PCSK9 and breast cancer survival: a Mendelian Randomization study https://www.medrxiv.org/content/10.1101/2025.10.03.25337270v1

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Hanbin Lee @epigenci.bsky.social · 6d

the biggest mystery of this school's computing cluster is that a more recent GPU has a shorter queue than the older one. People must be stuck at their default config script and never change it.

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Hanbin Lee @epigenci.bsky.social · 6d

downtown detroit got really nice over the past year

and AA is so damn overpriced.

Hanbin Lee @epigenci.bsky.social · 6d

genuinely considering moving to detroit after getting candidacy and only going to work 3 days a week

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Hanbin Lee @epigenci.bsky.social · 6d

midwest weather is so *hot* these days

Hanbin Lee @epigenci.bsky.social · 6d

cs.rice.edu/~ogilvie/com...

Likelihood of a tree

The likelihood of a tree is the probability of a multiple sequence alignment or matrix of trait states (commonly known as a character matrix) given a tree topology, branch lengths and substitution mod...

cs.rice.edu

Hanbin Lee @epigenci.bsky.social · 6d

tskit.dev/tskit/docs/s...

Python API — Tskit manual

tskit.dev