Lightnews — Scholar-powered news

Professor Mac @eagleeye1906.bsky.social · 1m

Nah bruh, that’s Columbo. Columbus is an equilateral quadrilateral whose four sides all have the same length

Jawn Redcorn @jerzeejoker.bsky.social · 5m

No that’s Cum Laude

Columbus is an American crime drama television series starring Peter Falk as a detective in the LAPD

Alex Mack 10 🇯🇲 @chillarybanks.com · 1h

That’s Cumulus.

Columbus is a Latin term meaning, “with honor.”

Professor Mac @eagleeye1906.bsky.social · 5m

Enzo Palumbo

Katelyn Boo-urns @katelynburns.com · 4h

name an italian more worthy of an american holiday than columbus

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Zelena Sage @zelenasage.blacksky.app · 8h

Shots fired 😂😩😂😩

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⚜️New Logic @freshlogic.blacksky.app · 14m

This why the “touch grass” part of the SM dogpile be so critical.

You gotta go step away. Trust me, I speak from experience

Go outside, real life gonna shake you back.

And you gonna move on. 😂😂

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SoloChills @solochills.blacksky.app · 15h

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Professor Mac @eagleeye1906.bsky.social · 18h

THIS IS THE DAY

THAT THE LORD HAS MADE

I WILL REJOICE

AND BE GLAD IN IT

Sickos Committee @sickoscommittee.org · 18h

Trent Dilfer is out at UAB.

The DILFsaster is over.

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Ken Tremendous @kentremendous.bsky.social · 22h

Honestly this was one of the weirdest things I've ever seen. This was the OPS called on Diggs, and the flag was thrown like a full 30 seconds after the TD scored on the opposite end of the field, 40 yards from this interaction.

Andrew Callahan @andrewcallahan.bsky.social · 23h

This "offensive pass interference" erased a 61-yard TD for the #Patriots. Outrageous call.

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Professor Mac @eagleeye1906.bsky.social · 22h

a cartoon of a baby laying on the floor and the words i hate it here

ALT: a cartoon of a baby laying on the floor and the words i hate it here

media.tenor.com

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Aaron Rupar @atrupar.com · 1d

Q: Who is Mike Johnson being threatened by? I mean, if he's not bringing the House back, releasing the Epstein files ... he seems scared

MARJORIE TAYLOR GREENE: I think so ... Do I think he's really up to the task? No.

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Professor Mac @eagleeye1906.bsky.social · 23h

Sending London Vikings/Browns & Jets/Broncos should be enough to have us sanctioned

Ken Tremendous @kentremendous.bsky.social · 23h

I know England used to rule us with a tyrannical king, but sending them this as revenge is uncalled for.

Jets' stats for the London game: 82 total yards, 8 first downs, 0/0 in the red zone

Professor Mac @eagleeye1906.bsky.social · 23h

Still mad at that wack ass DJ at The Patio last night @ellofuzzy.bsky.social

Playing Dipset deep cuts sir we are in ATLANTA

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Professor Mac @eagleeye1906.bsky.social · 1d

A rising Jameis lifts all boats.

He wouldn’t even need to move

charles (young QB agnostic) mcdonald @fourverts.bsky.social · 1d

the jets averaged 1.4 yards per play today

54 plays
82 yards

42% of their plays failed to gain a yard
-10 net passing yards

Reposted by Professor Mac

Chise @sailorrooscout.bsky.social · 1d

Researchers envision their vaccine being used as both a treatment and a preventive, and as an approach to treating multiple cancer types.
• www.umass.edu/news/article...

The study has been published in Cell Reports Medicine. YES, it is PEER-REVIEWED.
• www.cell.com/cell-reports...

🧪🧵⬇️

HIGHLIGHTS
•Lipid NPs carrying STING and TLR4 agonists promote synergistic type I interferons
• NPs drain efficiently to lymph nodes and increase polyfunctional T and B cells
• NPs improve tumor-free outcomes with memory against multiple aggressive tumor models
SUMMARY
We report on the utility of a "super-adjuvant" nanoparticle (NP) system as a modular, customizable platform for next-generation cancer vaccination. Using nanomaterials engineering technology, we aim to harness not only the effective adjuvanticity of whole-pathogen vaccines, but also the safety of subunit vaccines.
Our lipid-based NP platform co-encapsulates agonists of the stimulator of interferon genes (STING) and Toll-like receptor 4 (TLR4) pathways to promote synergistic production of type I interferons and other
proinflammatory cytokines in innate antigen-presenting dendritic cells and macrophages.
Compared to empty NPs and free agonists, dual-adjuvant NPs administered with antigenic peptides or tumor cell lysate promote increased antigen processing and presentation, drain efficiently to nearby lymph nodes, increase polyfunctional tumor-specific T and B cells, and improve tumor-free outcomes upon vaccination and subsequent challenge with multiple aggressive tumor cells.

Graphical Abstract

The vaccine combines two immune-stimulating molecules (adjuvants) in a tiny lipid nanoparticle that enhances both innate and adaptive immune responses. The innate immune system acts as the body’s first line of defense, responding quickly and non-specifically to invaders using cells that release inflammatory signals. The adaptive immune system takes longer to activate but provides a targeted, long-lasting response, training T-cells and B- cells to recognize and remember specific threats. Together, they form a coordinated defense: the innate system alerts and activates the adaptive system, which then delivers precise and durable immunity.

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Chise @sailorrooscout.bsky.social · 1d

GOOD NEWS! Researchers have developed a cancer vaccine that has shown STUNNING results, PREVENTING up to 88% of MULTIPLE aggressive cancers by harnessing dual-pathway nanoparticles that train the immune system to recognize and destroy tumor cells. In some cases, it COMPLETELY prevented metastasis.

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Professor Mac @eagleeye1906.bsky.social · 1d

I cannot imagine cooning at all, but being this deep in the coonery???

Aaron Rupar @atrupar.com · 1d

BREAM: Federal workers in Virginia lost jobs bc of DOGE. Your opponent points out unemployment is up under Youngkin/Sears

EARLE-SEARS: Actually unemployment is down

B: She points to numbers from BLS showing unemployment is up. Do you quibble w/data?

S: I don't know where she's getting stats from

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Black Single Mom @momsingleblack.bsky.social · 1d

A disgusting individual.

Aaron Rupar @atrupar.com · 1d

BREAM: Federal workers in Virginia lost jobs bc of DOGE. Your opponent points out unemployment is up under Youngkin/Sears

EARLE-SEARS: Actually unemployment is down

B: She points to numbers from BLS showing unemployment is up. Do you quibble w/data?

S: I don't know where she's getting stats from

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Brendan Nyhan @brendannyhan.bsky.social · 1d

If you're going to write headlines like this, why even have newspapers?

Old White Nepo Hat @kenwhite.bsky.social · 1d

Should the New York Times be sold to Pennysaver and its editors sent to work in Amazon warehouses? It depends on who you ask.

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Jay Perk @johnathanperk.bsky.social · 1d

I’m serious as a heart attack.

Jay Perk @johnathanperk.bsky.social · 3d

The Supreme Court will rule same-sex marriages unconstitutional during the 2026 calendar year.

Start preparing yourselves now and making plans accordingly.

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Mel @thegatesofmel.blacksky.app · 1d

I’m gonna say this - with love - about this. Stop telling me how dim the police and these agencies are and giving them an out when the answer is hatefulness.

The only reason you think a fragrant LABLED perfume bottle came from a den in the 19th century is racism.

Mel @thegatesofmel.blacksky.app · 2d

Calling these things “mistakes” is disingenuous and lazy. A 45 year old fragrance in a bottle that is scented like the fucking fragrance is not a damn drug and everyone knows that. www.nbcnews.com/news/asian-a...