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Nicholas Bauer PhD

@bioturbonick.net

4.2K followers 1.6K following 18K posts

Computational biology and superresolution microscopy. Tech and politics nerd. Promoter of rationality. Progressive. Somerville, MA Signal: BioTurboNick.24

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Nicholas Bauer PhD @bioturbonick.net · Jan 7

It ends:

"So, unfortunately, the only message that the public will receive from this “peaceful transfer of power” is: We surrender."

Democrats’ high road in peaceful transfer of power feels like a dead end

In her article “As Harris certifies her own loss, some see message about democracy” (Page A1, Jan. 4), Tal Kopan presents the view of top Democrats, including our own Senator Elizabeth Warren, that not making a stand to object to Donald Trump’s reelection is “the right thing to do,” that it shows “we still believe in following the Constitution.”

Maybe there once was a world where that could be true, but that is not this world.

Trump’s election to a second term is the culmination of the Jan 6, 2021, insurrection. Our Founders knew a Republic cannot hand power to an insurrectionist and expect to get it back when his turn is up; Section 3 of the 14th Amendment to the Constitution, which Warren did not mention, exists to prevent this scenario.

So, unfortunately, the only message that the public will receive from this “peaceful transfer of power” is: We surrender.

Nicholas C. Bauer

Somerville

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Nicholas Bauer PhD @bioturbonick.net · 18m

Instead of worrying, say they *are* risking prosecution and court martial for following illegal orders.

Acyn @acyn.bsky.social · 49m

Kelly: I really worry about those aviators, drone operators, special forces guys that are in the Caribbean right now striking these boats and whether or not this is legal..

There’s no authorization for the use of military force. The Congress has not given that to the president. He hasn’t asked.

Nicholas Bauer PhD @bioturbonick.net · 24m

It feels like it should be dead simple for an email client to segregate such updates out for you. Lots of updates would be fine if they were organized and not in the main inbox. Cluster them and show me the most recent only.

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Reposted by Nicholas Bauer PhD

NOELREPORTS @noelreports.com · 30m

A Russian diesel-electric submarine, B-261 "Novorossiysk", surfaced near the coast of Brittany, France, reportedly due to serious technical issues. A French Navy frigate has been deployed to monitor the vessel. NATO confirmed the incident.

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Nicholas Bauer PhD @bioturbonick.net · 29m

I'm calling it on Cyberpunk 2077. There's nuggets of good in it but the game controls are annoying. Also I haven't managed to connect to my character at all halfway through the plot.

I think I'll replay RDR2 and then try out RDR1.

Reposted by Nicholas Bauer PhD

Nicholas Slayton @nslayton.bsky.social · 1h

The Texas Military Department confirmed to @taskandpurpose.com it had replaced some of the 200 National Guard troops sent to Chicago for not being "in compliance" with validation standards. This came after photos of heavyset NG members were widely mocked. taskandpurpose.com/news/texas-n...

Some Texas National Guard troops replaced in Illinois after failing to meet standards

An unspecified amount of Texas National Guard troops were replaced in Chicago, shortly after photos of their appearance were mocked.

taskandpurpose.com

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Reposted by Nicholas Bauer PhD

Andy Craig @andycraig.bsky.social · 1h

This is a good catch. The statutory authorization supposedly being used to transfer R&D funds to regular payroll is, in fact, expired, just like the regular appropriations are also expired.

Ira 'Bluebeard Homer' Goldman @kdbyproxy.bsky.social · 2h

Not that Trump/Vought/Hegseth gaf, but among other ways in which the law says this may NOT be done:
A) The part of 8005 I've underlined in green says money transferred to another account is "available… for the same time period" as that other account; that other acc't expired on Sept 30.

1/

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Nicholas Bauer PhD @bioturbonick.net · 1h

Put it in the DSM

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BeijingPalmer @beijingpalmer.bsky.social · 2h

whole thing is even worse than the headline when you think about what 'play' means here

“I’m just as concerned for you! Don’t worry about me! It would seem we are in this together and will have to rise above it. Otherwise keep in close touch and we’ll play some more soon!!!!”"

Eliot Higgins @eliothiggins.bsky.social · 2h

Prince Andrew told Jeffrey Epstein ‘we’re in this together’ in 2011 email www.theguardian.com/uk-news/2025...

Prince Andrew told Jeffrey Epstein ‘we’re in this together’ in 2011 email

Royal sent email after Virginia Giuffre photo emerged but later claimed he had ceased contact with Epstein in 2010

www.theguardian.com

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Reposted by Nicholas Bauer PhD

Olúfẹ́mi O. Táíwò @olufemiotaiwo.bsky.social · 4h

1) I once again take this opportunity to remind you: to keep its basic functioning, society has to discourage baldfaced lying, especially by authorities

2) is...is it happening?

Aaron Rupar @atrupar.com · 4h

STEPHANOPOULOS: I didn't insinuate anything. I asked you whether Tom Homan accepted $50k as was heard on an audio tape recorded by the FBI in September 2024. You did not answer the question. Thank you for your time.

VANCE: No, George, I sai--

STEPHANOPOULOS: We'll be right back

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Reposted by Nicholas Bauer PhD

Clay Ranck @clayranck.bsky.social · 4h

If they haven’t “resolved the issue,” then they shouldn’t be using the shadow docket to overturn long-standing precedents.

Aaron Rupar @atrupar.com · 4h

Amy Coney Barrett defends heavy use of the shadow docket: "If we wrote a long opinion, it might give the impression that we have finally resolved the issue, and in none of these cases have we finally resolved the issue."

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Nicholas Bauer PhD @bioturbonick.net · 4h

Sure, as soon as they get around to Hegseth and RFK Jr.

Nicholas Bauer PhD @bioturbonick.net · 4h

But it's useless. Calls to resign only possibly work if the boss actually thinks their underling is doing something wrong.

Reposted by Nicholas Bauer PhD

Aaron Rupar @atrupar.com · 4h

Pritzker: "If the Constitution means anything -- and I guess we all are questioning that right now -- the Insurrection Act cannot be invoked ... they just want troops on the ground because they want to militarize especially blue cities in blue states."

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Nicholas Bauer PhD @bioturbonick.net · 5h

Hmm. I guess I haven't seen those issues.

Nicholas Bauer PhD @bioturbonick.net · 5h

These calls for Trump's stooges and puppeteers to resign all fall flat because Trump doesn't care. Shame has no force in this regime.

There is only one battle that matters or which can change anything, and that's to remove Trump.

Joshua Weitz @joshuasweitz.bsky.social · 5h

www.merkley.senate.gov/schumer-merk...

Schumer, Merkley, Murray, Peters Call On Trump Budget Chief Russ Vought To Resign - Merkley

Washington, D.C. – Today, Senate Democratic Leader Chuck Schumer (D-NY) and US Senators Jeff Merkley (D-OR), Ranking Member of the Senate Budget Committee, Patty Murray (D-WA), Vice-Chair of the Senat...

www.merkley.senate.gov

Nicholas Bauer PhD @bioturbonick.net · 5h

What has become worse about Word?

Reposted by Nicholas Bauer PhD

Thomas Zimmer @thomaszimmer.bsky.social · 7h

It is October 2025, the assault on what is left of American democracy is escalating, and one of the New York Times’ most influential formats insists on presenting one of the Trumpist regime’s leaders as a devout “small government” conservative with a great work ethic.

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TJ McCorvie @allostericstate.bsky.social · 9h

Yikes! In this paper the AlphaFold model of human plasminogen (PDB-8uq6) has been refined into noise (EMD-42462) using Phenix & ISOLDE. For some reason the authors even interpret side-chain interactions:
#cryoEM

Image from the EMD entry EMD-42462 for human plasminogen bound to streptococcal surface enolase. Projections of the map are shown demonstrating no protein features and radial streaks due to overfitting.

EMD-424262 and PDB-8UQ6 opened in ChimeraX. Though the map is stated to be of Human Plasminogen bound to streptococcal surface enolase the authors have modelled only plasminogen in their PDB. The map shows radial streak at the surface indicative of overfitting and no clear density in the centre of the map corresponds to the model.

Figure 5 from the paper describing side chain interactions of human plasminogen from the PDB 8uq6.

Image showing the model to map FSC curve from Phenix which is the software used by the authors to real space refine their PDB into their cryo-EM map. The model to map FSC curve is a flat line showing no correlation exists between the cryo-EM map EMD-42462 and the PDB 8uq6.

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Nicholas Bauer PhD @bioturbonick.net · 16h

And freedom too, right?

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Metabo_Dave @metabodave.bsky.social · 22h

It feels like there is a good chance that Johnson never reconvenes the House.

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Ed Zitron @edzitron.com · 21h

AI has lost the dunce vote. It’s over

Nate Silver
@NateSilver538 • 5h
•.°
I'm just one person, and my programming needs are somewhat unusual (building various kinds of statistical forecasting models). But I'm just not seeing the consistent productivity gains from LLMs that I would have expected if you'd asked me 6 months ago.

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Ify Nwadiwe @ifycomedy.com · 21h

I think we really should stop using antifa and just fully say anti-fascist and get them saying they are against anti fascism. Using antifa is giving them some distance and I genuinely think some of their base don’t even know that’s what it stands for.

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Microplastics Spookmelier @leastactionhero.bsky.social · 18h

today in "predicted by 30 Rock"

Edie Falco on 30 Rock:
I MISSED THE VOTE ON A BILL TO LEGALIZE RECREATIONAL WHALE TORTURE.

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Nicholas Bauer PhD @bioturbonick.net · 17h

I suspect it's an extremely common mistake for plant buyers to make.

Reposted by Nicholas Bauer PhD

Sky Marchini @sky.skymarchini.net · 21h

So dominion voting got sold, look at this fascinating statement from their new owner (not to doom but this is, uh, suboptimal). www.dominionvoting.com

(Dominion voting website now redirecting to libertyvote.com with the following statement:)

Our Promise.
-
My Fellow Americans,
Today, I am proud to announce Liberty Vote - a 100% American-owned election technology company dedicated to restoring trust in our elections. Our mission is clear: every vote must be secure, fair, and verifiable.
I have spent my life working to strengthen America's elections. That commitment began years ago, in the aftermath of the 2000 election, when I worked for the Missouri Secretary of State. Later, as Election Director in St. Louis, I led the effort to modernize outdated systems and rebuild public trust. Eventually, I founded an election technology company that today serves nearly one in four voters nationwide.
With Liberty Vote, we are building on that legacy. We are turning the page and beginning the vital work of restoring faith in American elections. While these changes will not happen overnight, Liberty Vote's mission is rooted in American values and committed to transparency, independent audits, and verifiable paper records.
Our purpose is simple: to ensure that America's elections are secure, fair, and honest.
Scott Leiendecker
Founder and Chairman, Liberty Vote

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