Alan McNally
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alanmcn1.bsky.social
Alan McNally
@alanmcn1.bsky.social
6.5K followers 590 following 1.8K posts

Head of the School of Infection, Inflammation & Immunology @ Uni Birmingham. Proud Scot. Oversaw a few Covid PCR tests

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Alan McNally is a professor of microbial genomics at the University of Birmingham, UK. He works on the evolutionary genomics and antimicrobial resistance in bacterial pathogens.

Source: Wikipedia
Biology 75%
Medicine 8%
Posts Replies Media Videos

Reposted by Alan McNally

anonopin.bsky.social
Anon Opin @anonopin.bsky.social · 1h
It's fucking ridiculous that it's cheaper to get a plane from London to Glasgow than a train.

Reposted by Alan McNally

brockhurstlab.bsky.social
Michael Brockhurst @brockhurstlab.bsky.social · 1h
What a week! Thanks to everyone who attended the UK Phage Therapy workshop and #MicroEvo25 in Liverpool… every talk, poster, question, chat, and round of applause helps to build our microbial evolution community! Thanks to @microbiologysociety.org and @ukri.org for support

alanmcn1.bsky.social
Alan McNally @alanmcn1.bsky.social · 2h
This is amazing!

alanmcn1.bsky.social
Alan McNally @alanmcn1.bsky.social · 2h
Wow
samjwilsonphd.bsky.social Sam J Wilson @samjwilsonphd.bsky.social · 3h
How does fever work?

Our new Science paper shows how elevated body temperature can protect against severe influenza and that avian-origin viruses escape this defence.

This is likely one reason why bird flus and some pandemic influenzas can be so severe.🧵

www.science.org/doi/10.1126/...
Avian-origin influenza A viruses tolerate elevated pyrexic temperatures in mammals
Host body temperature can define a virus’s replicative profile—influenza A viruses (IAVs) adapted to 40° to 42°C in birds are less temperature sensitive in vitro compared with human isolates adapted t...
www.science.org

Reposted by Alan McNally

anonopin.bsky.social
Anon Opin @anonopin.bsky.social · 2h
If I was prime minister I'd hike up alcohol duty in shops and massively lower it in pubs. Seems like a win-win for society.

alanmcn1.bsky.social
Alan McNally @alanmcn1.bsky.social · 2h
What has happens to the Detroit OL

alanmcn1.bsky.social
Alan McNally @alanmcn1.bsky.social · 2h
Was a joy. Give my best to Pal and am sure we will now be chatting for years to come!

Reposted by Greg Linden, Alan McNally

samjwilsonphd.bsky.social
Sam J Wilson @samjwilsonphd.bsky.social · 3h
How does fever work?

Our new Science paper shows how elevated body temperature can protect against severe influenza and that avian-origin viruses escape this defence.

This is likely one reason why bird flus and some pandemic influenzas can be so severe.🧵

www.science.org/doi/10.1126/...
Avian-origin influenza A viruses tolerate elevated pyrexic temperatures in mammals
Host body temperature can define a virus’s replicative profile—influenza A viruses (IAVs) adapted to 40° to 42°C in birds are less temperature sensitive in vitro compared with human isolates adapted t...
www.science.org

alanmcn1.bsky.social
Alan McNally @alanmcn1.bsky.social · 3h
I usually hate NFL half time shows but the world has just learned that it really needs a Jack White/Eminem hook up!

alanmcn1.bsky.social
Alan McNally @alanmcn1.bsky.social · 3h
and meeting some lovely and amazingly talented ECRs for the first time @padpadpadpad.bsky.social @elisasosa.bsky.social @ellinoralseth.bsky.social @ariannebabina.bsky.social to name a few

alanmcn1.bsky.social
Alan McNally @alanmcn1.bsky.social · 3h
And you. I have a new Glasgow Brethren friend

Reposted by Alan McNally

ariannebabina.bsky.social
Arianne Babina @ariannebabina.bsky.social · 4h
Great meeting you, Alan!

Reposted by Alan McNally

rsmythfreelance.bsky.social
Richard Smyth @rsmythfreelance.bsky.social · 5h
"Dickensian"
A light-up acrylic Dickensian snowman.

alanmcn1.bsky.social
Alan McNally @alanmcn1.bsky.social · 6h
Absolutely brilliant #MicroEvo25 some great talks and talent that has me thinking about our research. And great to catch up with @brockhurstlab.bsky.social @craigmaclean.bsky.social @paulhoskisson.bsky.social
@lore-fermar.bsky.social @julieakmcdonald.bsky.social @lucyweinert.bsky.social and more

Reposted by Alan McNally

dempster2000.bsky.social
Sarah Dempster @dempster2000.bsky.social · 8h
The power of Crufts compels you

Reposted by Katharine Hayhoe, Brad R. Humphreys, Jacalyn Duffin , and 7 more

erikangner.com
Erik Angner @erikangner.com · 13h
"Runctitiononal features"? "Medical fymblal"? "1 Tol Line storee"? This gets worse the longer you look at it. But it's got to be good, because it was published in Nature Scientific Reports last week: www.nature.com/articles/s41... h/t @asa.tsbalans.se
Infographic with AI slop published in Nature Scientific Reports

Reposted by Jesse M. Shapiro, Alan McNally

josiebryant.bsky.social
Josie Bryant @josiebryant.bsky.social · 2d
Really pleased to share the first paper to come out of the lab.
We found that hospital patients were frequently colonised with P. aeruginosa and that the same clone was shared between the gut and the lung.
The phylogenies indicate that the clones moved from lung->gut

www.nature.com/articles/s41...
High frequency body site translocation of nosocomial Pseudomonas aeruginosa - Nature Communications
Here, the authors report within-host diversity and body site translocation dynamics in hospital samples of Pseudomonas aeruginosa and reveal that body site sharing was likely due to within-patient tra...
www.nature.com

alanmcn1.bsky.social
Alan McNally @alanmcn1.bsky.social · 4d
Eagles in Kelly Green is a sight

alanmcn1.bsky.social
Alan McNally @alanmcn1.bsky.social · 4d
For

alanmcn1.bsky.social
Alan McNally @alanmcn1.bsky.social · 4d
Conferencing this week. Very rare for me now and very selective. Can’t wait fur two days of microbial evolution

alanmcn1.bsky.social
Alan McNally @alanmcn1.bsky.social · 4d
Even if they do it won’t be as bad as the early season melt of everyone else!

alanmcn1.bsky.social
Alan McNally @alanmcn1.bsky.social · 4d
Arsenal are champions elect

Reposted by Lisa W. Fazio, David Dunning, Julie L. Lockwood , and 12 more

alanallport.bsky.social
Alan Allport @alanallport.bsky.social · 4d
Really important to stress that the Crown Jewels of the US higher education system were never the Ivies or elite SLACs (other countries have equivalents of these) but the well-funded, large, cheap, and excellently staffed public state university systems bringing high quality education to the masses.
jackiantonovich.bsky.social Jacqueline Antonovich @jackiantonovich.bsky.social · 4d
One of the bragging rights that the US ed system had in the 20th century is that we didn't have education tracks. Essentially, any kid could go to a CC or state school & major in whatever they wanted to (obviously an oversimplification). I fear this aspect of the American dream is dying.

Reposted by Alan McNally

bpfairfax.bsky.social
fairfaxlab @bpfairfax.bsky.social · 4d
If you have meningitis you are too unwell to have tumours resected.

It would be surprising if there was an undetected burden of subacute/chronic gram negative bacterial meningitis that was presumably asymptomatic.

alanmcn1.bsky.social
Alan McNally @alanmcn1.bsky.social · 5d
Can’t see anyone stopping South Africa doing a rugby World Cup hat trick. Hands down dominant team in the game

Reposted by Alan McNally

gjbarton.bsky.social
Geoff Barton @gjbarton.bsky.social · 5d
One of those November sunsets at Dundee Scotland today 😀

alanmcn1.bsky.social
Alan McNally @alanmcn1.bsky.social · 5d
Our field is disappearing in a mist

alanmcn1.bsky.social
Alan McNally @alanmcn1.bsky.social · 5d
Bingo. And then some

Reposted by Alan McNally

onisillos.bsky.social
Onisillos @onisillos.bsky.social · 5d
I wonder if it’s already time to update this editorial www.thelancet.com/journals/lan...

alanmcn1.bsky.social
Alan McNally @alanmcn1.bsky.social · 5d
FFS