Team hope/good trouble/go high💙
https://www.hopkinsmedicine.org/profiles/details/tanya-prowell
ja.ma/47p4fwG
ja.ma/47p4fwG
NEW RPCT: 5, 10, or 15d of Paxlovid in 156 immunocompromised (IC) outpatients w/ #COVID19. No diff in sustained viral suppression d15-44.
🔑 takeaways: Rebound isn’t rare (1 in 4 of severely IC), & enrichment/endpoint selection matter.
www.sciencedirect.com/science/arti...
NEW RPCT: 5, 10, or 15d of Paxlovid in 156 immunocompromised (IC) outpatients w/ #COVID19. No diff in sustained viral suppression d15-44.
🔑 takeaways: Rebound isn’t rare (1 in 4 of severely IC), & enrichment/endpoint selection matter.
www.sciencedirect.com/science/arti...
In mice, spike is sufficient to induce brain #PathSky & #PsychSky behavioral changes & exacerbates #NeuroSky damage.
mRNA vax reduced but didn’t eliminate spike burden. /1
#LongCovid
📅 Applications close: Aug 29, 2025
🔗 science.org.au/gtap/?utm_so...
📅 Applications close: Aug 29, 2025
🔗 science.org.au/gtap/?utm_so...
Prosp cohorts (China, N=74K):
At 8-10 yrs, EBV VCA-IgA was assoc w/:
Overall cancer risk ⬆️ 5x
Lung cancer 1.8x
Liver cancer 1.7x
Nasopharyngeal cancer 26x Lymphoma 3.2x
Dose-response +.
🔑 We need ways to prevent/treat mono.
#DrugDevelopment
www.nature.com/articles/s41...
Prosp cohorts (China, N=74K):
At 8-10 yrs, EBV VCA-IgA was assoc w/:
Overall cancer risk ⬆️ 5x
Lung cancer 1.8x
Liver cancer 1.7x
Nasopharyngeal cancer 26x Lymphoma 3.2x
Dose-response +.
🔑 We need ways to prevent/treat mono.
#DrugDevelopment
www.nature.com/articles/s41...
📢 Prospective cohort study (CO-FLOW) of adults hospitalized for #COVID19 finds only 1 in 8 fully recovered at 3m, & only 1 in 4 at 3y. More than half had ⬇️ memory & concentration at 3y. This is #LongCovid. HUGE unmet #DrugDevelopment need.
www.thelancet.com/action/showP...
📢 Prospective cohort study (CO-FLOW) of adults hospitalized for #COVID19 finds only 1 in 8 fully recovered at 3m, & only 1 in 4 at 3y. More than half had ⬇️ memory & concentration at 3y. This is #LongCovid. HUGE unmet #DrugDevelopment need.
www.thelancet.com/action/showP...
NEW study of outpatients w/ #COVID19 + self-reported #BrainFog after infection vs healthy controls finds marked hypometabolism on PET & brain wave changes on EEG corresponding to areas responsible for attention, memory, language, & decision-making. www.nature.com/articles/s41...
NEW study of outpatients w/ #COVID19 + self-reported #BrainFog after infection vs healthy controls finds marked hypometabolism on PET & brain wave changes on EEG corresponding to areas responsible for attention, memory, language, & decision-making. www.nature.com/articles/s41...
👉 9/25/25: in person (ASCO HQ, in DC area)
or
👉 1/29/26: virtual
See you there! #MedSky #OncSky #MedEd
👉 9/25/25: in person (ASCO HQ, in DC area)
or
👉 1/29/26: virtual
See you there! #MedSky #OncSky #MedEd
NEW: Randomized trial of exercise vs health ed in people w/ #ColonCancer after adjuvant chemo: disease-free (HR 0.72; 6.4% abs diff at 5y) & overall (HR 0.63; 7.1% abs diff at 8y) survival improved w/ exercise! NNT ~14. ACTUALLY tolerable. 🏆
www.nejm.org/doi/full/10....
NEW: Randomized trial of exercise vs health ed in people w/ #ColonCancer after adjuvant chemo: disease-free (HR 0.72; 6.4% abs diff at 5y) & overall (HR 0.63; 7.1% abs diff at 8y) survival improved w/ exercise! NNT ~14. ACTUALLY tolerable. 🏆
www.nejm.org/doi/full/10....
ascopubs.org/toc/edbk/cur...
#OncoAlert
ascopubs.org/toc/edbk/cur...
#OncoAlert
"Addressing #FinancialToxicity in #BreastCancer Care: Strategies for Mitigation and Support"
👉Education Session
🎯 Hall D2
📆 TODAY, May 30, 2025
⏲️ 1:00 - 2:15 PM CDT
My 🗝️ @ascocancer.bsky.social takeaways are below ⬇️
Don't miss it!
"Addressing #FinancialToxicity in #BreastCancer Care: Strategies for Mitigation and Support"
👉Education Session
🎯 Hall D2
📆 TODAY, May 30, 2025
⏲️ 1:00 - 2:15 PM CDT
My 🗝️ @ascocancer.bsky.social takeaways are below ⬇️
Don't miss it!
Learn how decimating the CDC will cost many lives in the US and abroad. #MedSky
Learn how decimating the CDC will cost many lives in the US and abroad. #MedSky
gift link www.wsj.com/health/welln...
gift link www.wsj.com/health/welln...
If you want to get up to speed on the #microbiome in #cancer literature, this review is an excellent summary.
jamanetwork.com/journals/jam...
If you want to get up to speed on the #microbiome in #cancer literature, this review is an excellent summary.
jamanetwork.com/journals/jam...
Invasive cardiopulm exercise testing (iCPET) at Brigham & Women’s finds people w/ #MECFS & #longCovid have symptomatic ⬇️ aerobic capacity at peak exercise due to preload insufficiency & impaired systemic O2 extraction, latter c/w peripheral L➡️R shunt &/or limb skel muscle dysfunction. /1
Invasive cardiopulm exercise testing (iCPET) at Brigham & Women’s finds people w/ #MECFS & #longCovid have symptomatic ⬇️ aerobic capacity at peak exercise due to preload insufficiency & impaired systemic O2 extraction, latter c/w peripheral L➡️R shunt &/or limb skel muscle dysfunction. /1