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JAMA @jama.com · 15h

💬 Viewpoint: To address rural hospital closures, a cohesive framework is needed that simplifies program enrollment, aligns financing with clinical needs, and streamlines accountability.

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A JAMA article titled "Rural Hospitals Deserve More Than Patchwork Policies," published online September 3, 2025. A table outlines a path toward supporting rural hospitals with a modern framework, comparing current state and modernized proposals.

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JAMA @jama.com · 16h

For patients with hypothermic cardiac arrest, ECLS is associated with increased survival and favorable neurological outcomes compared with other causes of cardiac arrest.

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A JAMA article titled "Extracorporeal Life Support in Accidental Hypothermia" by Konrad Mendrala, MD, PhD; Paweł Podsiadło, MD, PhD; Tomasz Darocha, MD, PhD, published online October 8, 2025. The article discusses accidental hypothermia and its treatment.

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JAMA @jama.com · 17h

📢 ICYMI: This comprehensive review on thyroid cancer offers an in-depth overview of current epidemiology, risk factors, diagnosis, molecular profiling, treatment strategies, and emerging therapies.

📍 Add to your reference manager: ja.ma/4h0KMqC

JAMA review: Thyroid Cancer. Shows antiangiogenic and targeted therapy in thyroid carcinoma pathway with targeted inhibitors such as Selpercatinib, Pralsetinib, Larotrectinib, Entrectinib, Dabrafenib, Trametinib, Sorafenib, Vandetanib, Lenvatinib, and Cabozantinib.

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JAMA @jama.com · 17h

Proactive, risk-stratified intraoperative MAP targets did not improve 6-month disability after elective noncardiac surgery compared with usual care MAP ≥65 mm Hg.

#ANES25 @asahq.bsky.social

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Infographic from JAMA shows study results: proactive blood pressure management didn't improve post-operative disability. 3247 patients analyzed, mean age 59. Mean WHODAS score: blood pressure management 17.7, usual care 18.2.

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JAMA @jama.com · 17h

💬 Editorial: Personalized perioperative blood pressure management did not reduce organ injury or disability compared with standard MAP targets.

#ANES25 @asahq.bsky.social

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A page from JAMA, published online October 12, 2025, featuring an editorial titled "Perioperative Outcomes—The Limits of Blood Pressure-Centered Strategies" by Matthieu Legrand et al. The article discusses intraoperative hypotension.

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JAMA @jama.com · 17h

Individualized perioperative MAP targets did not lower rates of organ injury or death after major abdominal surgery compared with routine blood pressure management at MAP ≥65 mm Hg.

#ANES25 @asahq.bsky.social

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Infographic from JAMA showing a study on perioperative blood pressure management for high-risk abdominal surgery patients. It concludes that individualized MAP targets didn't improve outcomes versus routine management.

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JAMA @jama.com · 19h

Among US hospitals, fewer annual cases are now needed to reach benchmark mortality for complex cancer surgery, challenging current Leapfrog Group minimum case volume recommendations.

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JAMA research letter: "Revisiting Minimum Case Volume Recommendations for Complex Surgery in Contemporary Practice". Figure 2 shows adjusted 30-day mortality for esophagus, stomach, liver and lung surgeries from 2005-2019.

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JAMA @jama.com · 20h

Active shooter drills are now near-universal in US schools.

Although they’re an important aspect of emergency preparedness, they may also cause some students psychological distress. ja.ma/470Fffg

The Psychological Toll of School Active Shooter Drills

This Medical News article discusses findings and recommendations from a recent National Academies of Sciences, Engineering, and Medicine report about how active shooter drills affect students.

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JAMA @jama.com · 1d

A randomized trial of simulated snow burial demonstrated that among healthy adults, a user-carried safety device delayed hypoxemia and hypercapnia, with the goal of increasing avalanche survival rates.

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JAMA study: Does a novel device delay hypoxemia during avalanche burial? A user-carried avalanche safety device delivers airflow, delaying hypoxemia. Findings: Safety device = 35 mins, 0 terminations; Control = 6.4 mins, 7 terminations.

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JAMA @jama.com · 1d

💬 Perspective: The evaluation of moderate alcohol consumption on health is complex due to known harms of heavy drinking, potential benefits of low consumption, varying evidence quality, and biases.

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A JAMA article titled "The Complexity of Research on Moderate Alcohol Consumption and Health: The Consensus Report From NASEM" by Ned Calonge et al., published online September 30, 2025.

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JAMA @jama.com · 1d

From 2014 to 2024, 1.6 billion inhalers for #asthma and #COPD dispensed in the US generated 24.9 million metric tons of CO₂e, with metered-dose inhalers responsible for 98% of emissions and $5.7 billion in social costs.

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Figure 1: Inhaler Utilization and Greenhouse Gas Emissions by Therapeutic Class, 2014-2024. Two bar graphs compare inhaler types (short-acting β-agonists, inhaled corticosteroids, etc.) against inhalers dispensed and greenhouse gas emissions.

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JAMA @jama.com · 1d

💬 Viewpoint: The FDA's updated guidance on accelerated approval aims to expedite therapy access while ensuring safety and efficacy, but it lacks specific standards for enforcement and trial evaluation.

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A JAMA article titled "Revisiting the FDA's Accelerated Approval Pathway" by Asha Kodan, Joseph T. Kannarkat, and G. Caleb Alexander, published online September 8, 2025. The article discusses the FDA's recent guidance on confirmatory trials.

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JAMA @jama.com · 1d

🎙️ In the latest episode of JAMA Editor's Summary, JAMA Editor in Chief Kirsten Bibbins-Domingo, PhD, MD, MAS, and Deputy Editor Preeti Malani, MD, MSJ, discuss the latest science published in JAMA.

Listen now: ja.ma/4nLDNoc

Editor’s Summary by Kirsten Bibbins-Domingo, PhD, MD, MAS, Editor in Chief and Preeti Malani, MD, MSJ, Deputy Editor of JAMA, the Journal of the American Medical Association, for articles published from October 4-10, 2025.

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JAMA @jama.com · 1d

💬 Viewpoint: President Trump's use of executive orders to restrict gender-affirming care undermines medical regulation, infringes on physician autonomy, and contravenes legal frameworks.

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A JAMA viewpoint article titled, "Federal Funding Conditions Threaten Gender-Affirming Care Access and Physician Autonomy" by Carmel Shachar, Julia Lynch, and Kevin Costello, published online September 4, 2025.

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JAMA @jama.com · 2d

The importance of oral health may extend to cancer prevention.

New research finds that bacteria and fungi from the mouth may affect pancreatic #cancer risk.

#microbiome

Oral Microbes and Pancreatic Cancer

This Medical News article discusses research linking oral bacteria and fungi with pancreatic cancer risk, highlighting microbial signatures that may inform future screening strategies.

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JAMA @jama.com · 2d

IV hydration spas promise to cure hangovers and boost immunity.

But with limited oversight and sparse clinical evidence, are the infusions safe?

Are IV Hydration Spas Safe?

This Medical News article discusses new research into the rise of intravenous hydration spas and the perceived benefits and known risks that come with the unproven treatments.

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JAMA @jama.com · 2d

Patients with bronchiectasis have permanently inflamed and dilated airways.

This JAMA Patient Page describes bronchiectasis symptoms, risk factors, diagnosis, and treatments.

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Diagram illustrating bronchiectasis, a lung condition with inflamed, widened airways. It shows a comparison of healthy vs. affected airways, symptoms like cough, and recommended treatments including airway clearance and antibiotics.

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JAMA @jama.com · 2d

The US Food and Drug Administration (FDA)'s authorization of #AI devices for #Alzheimer disease is promising but lacks transparency in demographic data, risking algorithmic bias and inequitable application across diverse patient groups.

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A research letter from JAMA, published July 30, 2025, focuses on demographic data supporting FDA authorization of AI devices for Alzheimer's disease and related dementias. Table 1 shows characteristics of AI, ML devices cleared for related dementias.

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JAMA @jama.com · 3d

Will 2026 be the year of real-world evidence that #AI can actually improve patient care?

JAMA+ AI EIC Roy Perlis, MD, MSc, and Associate Editor Yulin Hswen, ScD, MPH, discuss in this special episode marking 1 year since the launch of JAMA+ AI:

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JAMA+ AI article "What Will Next Year Bring for AI in Health?" by Roy Perlis. Published online October 9, 2025. Features headshots of JAMA+ AI Editors Yulin Hswen and Roy Perlis.

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JAMA @jama.com · 3d

Emergency Medicaid accounts for less than 1% of total #Medicaid spending, even in states with large undocumented populations.

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A JAMA "Research Letter" published online October 9, 2025, shows a US map depicting 'Emergency Medicaid Spending for Undocumented Immigrants.' States are color-coded to show the percentage of spending, ranging from 1 to 2%.

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JAMA @jama.com · 3d

Editorial: Postoperative AF after cardiac surgery is often transient, with rare recurrence beyond 30 days, differing in pattern and risk from nonsurgical AF.

#EACTS2025

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A page from JAMA, dated October 9, 2025, titled "Is There Really Something Different About Postoperative Atrial Fibrillation After Cardiac Surgery?" by Gregory M. Marcus, MD, MAS.

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JAMA @jama.com · 3d

Among patients with insertable cardiac monitors after CABG, the cumulative 1-year incidence of new-onset AF was 48%, yet median AF burden after 30 days was nearly zero.

#EACTS2025 @eacts.bsky.social

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JAMA | Original Investigation: "Long-Term Continuous Monitoring of New-Onset Atrial Fibrillation After Coronary Artery Bypass Grafting." Includes graphs of cumulative incidence and atrial fibrillation burden post-surgery.

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JAMA @jama.com · 3d

The US Food and Drug Administration accelerated approval pathway spans many nononcologic diseases, especially nonmalignant hematology and neurology, with 25% for infectious disease vaccines.

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A research letter from JAMA, published on October 7, 2025, titled "Regulatory and Clinical Outcomes of Nononcology Accelerated Approvals." It includes Table 1 showing characteristics of approvals from 2013-2024, listing disease areas and FDA designations.

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JAMA @jama.com · 3d

Approximately 2.6 million people in the US used methamphetamine in 2023.

This JAMA Insights discusses the health consequences of methamphetamine use and recommends comprehensive care strategies.

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A page from JAMA titled 'Methamphetamine Use Disorder.' It details the drug's effects, use statistics, medical and behavioral treatments, and risks, mentioning harm reduction programs and the ASAM/AAAP guidelines.

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JAMA @jama.com · 4d

For patients with hypothermic cardiac arrest, ECLS is associated with increased survival and favorable neurological outcomes compared with other causes of cardiac arrest.

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