Eric Topol
banner
erictopol.bsky.social
Eric Topol
@erictopol.bsky.social

Eric Jeffrey Topol is an American cardiologist, scientist, and author. He is the founder and director of the Scripps Research Translational Institute, a professor of Molecular Medicine and Executive Vice-President at Scripps Research Institute, and a senior consultant at the Division of Cardiovascular Diseases at Scripps Clinic in La Jolla, California. .. more

Medicine 88%
Public Health 4%
Pinned
A new cover for SUPER AGERS after making the NYT bestseller list. Thanks to you for making it the #1 ranked new non-fiction book on Amazon.
amazon.com/gp/new-relea...

AI and the New Science of Medicine
today @nejm.org
"the science of medicine is ready for reinvention"
"AI generates hypotheses, but those hypotheses are tested the old-fashioned way, avoiding the myriad statistical problems of relying on AI alone for discovery."
nejm.org/doi/full/10....
Bedside to Bench — AI and the New Science of Medicine | NEJM
Today, medical research builds up an understanding of the whole from molecular parts, but artificial intelligence can revive an approach building down from patient-level data to theory and understa...
nejm.org

Today's NYT front page.
A methodical quest and the latest salvo

One proposed strategy to promote a youthful immune system and human healthspan is to rejuvenate our thymus gland. Can we learn from this exceptional (and peculiar looking) vertebrate that can do this?
science.org/doi/10.1126/...

Reposted by Karen O’Leary

The direct causal evidence of ultra-processed foods for adverse health outcomes is accruing
nature.com/articles/s41...

How do the metabolic waste products get cleared from our brain? And how does this process intersect with the brain's immune system?
An exceptional review by
@jonykipnis.bsky.social
and colleagues
cell.com/neuron/fullt...
Resolving the mysteries of brain clearance and immune surveillance
This review by Kipnis et al. explores recent advances in brain fluid dynamics, emphasizing CSF flow’s role in waste clearance, the glymphatic and meningeal lymphatic systems, and neuroimmune interacti...
cell.com

Today.
"Or they simply don't know what they are doing"
wapo.st/4rE11ib

A new review of post-infection syndromes, including #LongCovid, and its diverse immunologic manifestations www.cell.com/trends/immun... by @virusesimmunity.bsky.social and colleagues

Thank you! That means a lot to me

Reposted by Dana Howard

Thanks @robcaliff.bsky.social and 11 other prior FDA Commissioners for weighing in on vaccines, evidence, appropriate policy in today's @nejm.org www.nejm.org/doi/full/10....
www.statnews.com/2025/12/03/f...

Reposted by Robert C. Richards

The harmful and biased medical advice from social medial influencers, highlighting lack of expertise and financial conflicts. Many specific examples and recommendations provided
bmj.com/content/391/...

Thanks @theguardian.com for their selection of SUPER AGERS as one of the best science books of 2025
www.theguardian.com/books/2025/d...

The outsized role of our brain astrocytes
nature.com/articles/d41...

Agree, Derek. I wrote about that point recently
erictopol.substack.com/p/the-peptid...
The Peptide Craze
The Surge in Use of Off-Label and Non-FDA Approved Peptides
erictopol.substack.com

Your blood concierge, the blood testing craze, and related, unproven, potentially unsafe BS
"Peptides like BPC-157 are injected as casually as espresso shots, while NAD fills IV bags with the promise of a youthful glow."
www.vanityfair.com/hollywood/st...

Reposted by Eric J. Topol