Eric Topol
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erictopol.bsky.social
Eric Topol
@erictopol.bsky.social
150K followers 310 following 2.8K posts

physician-scientist, author, editor

https://www.scripps.edu/faculty/topol/
Ground Truths https://erictopol.substack.com
SUPER AGERS https://www.simonandschuster.com/books/Super-Agers/Eric-Topol/9781668067666

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Eric Jeffrey Topol is an American cardiologist, scientist, and author. He is the founder and director of the Scripps Research Translational Institute, a professor of Molecular Medicine and Executive Vice-President at Scripps Research Institute, and a senior consultant at the Division of Cardiovascular Diseases at Scripps Clinic in La Jolla, California. .. more

Medicine 88%
Public Health 4%
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erictopol.bsky.social
Eric Topol @erictopol.bsky.social · May 27
A new cover for SUPER AGERS after making the NYT bestseller list. Thanks to you for making it the #1 ranked new non-fiction book on Amazon.
amazon.com/gp/new-relea...

erictopol.bsky.social
Eric Topol @erictopol.bsky.social · 23h
Across > 20 cancer types, >14,000 patients, + independent validation. Panel at right shows prognostic informativeness

erictopol.bsky.social
Eric Topol @erictopol.bsky.social · 23h
A major advance in cancer using multimodal AI to do virtual proteomics of H&E slides, unraveling the tumor microenvironment, key proteins, biomarkers, and informing prognosis
@cellcellpress.bsky.social @hoifungpoon.bsky.social
@msftresearch.bsky.social

cell.com/cell/fulltex...
Multimodal AI generates virtual population for tumor microenvironment modeling
GigaTIME leverages multimodal AI to generate virtual multiplex immunofluorescence (mIF) profiles from standard H&E slides, enabling comprehensive tumor immune microenvironment modeling across a large ...
cell.com

erictopol.bsky.social
Eric Topol @erictopol.bsky.social · 23h
Cancer-Detecting Blood Tests: "Limited research on the tests' effectiveness and whether the benefits outweigh the potential harms". A critical issue is assessment in low-risk patients by age 50+ only.
www.nytimes.com/2025/12/02/w...
My review erictopol.substack.com/p/the-larges...
Cancer-Detecting Blood Tests Are on the Rise. Do They Work?
www.nytimes.com

erictopol.bsky.social
Eric Topol @erictopol.bsky.social · 1d
How the "ready-made" cells are made

erictopol.bsky.social
Eric Topol @erictopol.bsky.social · 1d
A big advance, folks, for off-the-shelf, universal, engineered (base-edited) T cells achieving complete response vs incurable leukemia in several patients
www.nejm.org/doi/full/10....

erictopol.bsky.social
Eric Topol @erictopol.bsky.social · 1d
The impact of forever chemicals (PFAS) in drinking water on infant mortality, preterm birth, low-weight births and economic consequences (<-Figure 11 states)
@pnas.org
www.pnas.org/doi/abs/10.1...

erictopol.bsky.social
Eric Topol @erictopol.bsky.social · 1d
"Susan has long established herself as someone who puts evidence in service of the country above all."—
@jennifernuzzo.bsky.social

erictopol.bsky.social
Eric Topol @erictopol.bsky.social · 1d
Our recent conversation here
erictopol.substack.com/p/dr-susan-m...
Dr. Susan Monarez—Former CDC Director, First Live Interview
An American hero for standing up for science and public health
erictopol.substack.com

erictopol.bsky.social
Eric Topol @erictopol.bsky.social · 1d
The top 10 people of 2025 @nature.com who shaped science.
Recognizes Dr. Susan Monarez, the CDC Director who was "fired for holding the line on scientific integrity"
www.nature.com/immersive/d4...

erictopol.bsky.social
Eric Topol @erictopol.bsky.social · 2d
The many types of cholesterol :-)

erictopol.bsky.social
Eric Topol @erictopol.bsky.social · 2d
His legendary work spawned two life science fields: molecular biology and neuroscience. But that's only part of a much bigger story. An enthralling Ground Truths conversation with @matthewcobb.bsky.social on his new book CRICK
erictopol.substack.com/p/the-story-...
The Story of Francis Crick, a new masterpiece biography by Matthew Cobb
His legendary contributions and remarkable flaws
erictopol.substack.com

Reposted by Stanislas Dehaene, Joel Z. Leibo

erictopol.bsky.social
Eric Topol @erictopol.bsky.social · 2d
The exemplar of superhuman A.I. performance to date
www.nytimes.com/2025/12/02/o...

erictopol.bsky.social
Eric Topol @erictopol.bsky.social · 3d
Letter from Congress to FDA re: undermining vaccines, page 1 of 6

erictopol.bsky.social
Eric Topol @erictopol.bsky.social · 4d
AI and the New Science of Medicine
today @nejm.org
"the science of medicine is ready for reinvention"
"AI generates hypotheses, but those hypotheses are tested the old-fashioned way, avoiding the myriad statistical problems of relying on AI alone for discovery."
nejm.org/doi/full/10....
Bedside to Bench — AI and the New Science of Medicine | NEJM
Today, medical research builds up an understanding of the whole from molecular parts, but artificial intelligence can revive an approach building down from patient-level data to theory and understa...
nejm.org

erictopol.bsky.social
Eric Topol @erictopol.bsky.social · 4d
Today's NYT front page.
A methodical quest and the latest salvo

erictopol.bsky.social
Eric Topol @erictopol.bsky.social · 4d
One proposed strategy to promote a youthful immune system and human healthspan is to rejuvenate our thymus gland. Can we learn from this exceptional (and peculiar looking) vertebrate that can do this?
science.org/doi/10.1126/...

Reposted by Karen O’Leary

erictopol.bsky.social
Eric Topol @erictopol.bsky.social · 4d
The direct causal evidence of ultra-processed foods for adverse health outcomes is accruing
nature.com/articles/s41...