Rocky Diegmiller
@rdiegmiller.bsky.social
Di Talia and Poss lab postdoc applying computational approaches to better understand the dynamics of regeneration. Montani semper liberi.
Reposted by Rocky Diegmiller
🎉Paper alert! How do #axolotls regrow their limbs to match their body size? A new publication by PoL @friedrich-group.bsky.social along with @tatianasg.bsky.social @crtd-tud.bsky.social shows that opposing morphogen gradients scaling with animal size are key.
Curious? Read our news: tud.link/z6tj5y
Curious? Read our news: tud.link/z6tj5y
Morphogen Math: A Model of Axolotl Limb Growth during Regeneration
In a new publication led by the Friedrich group at PoL and the Sandoval-Guzmán group at CRTD, scientists propose a model of morphogen scaling during limb regeneration in axolotls.
tud.link
November 26, 2025 at 10:18 AM
🎉Paper alert! How do #axolotls regrow their limbs to match their body size? A new publication by PoL @friedrich-group.bsky.social along with @tatianasg.bsky.social @crtd-tud.bsky.social shows that opposing morphogen gradients scaling with animal size are key.
Curious? Read our news: tud.link/z6tj5y
Curious? Read our news: tud.link/z6tj5y
Reposted by Rocky Diegmiller
#DBfeature 🐠
A new powerful live imaging platform tracks Erk signalling dynamics in developing zebrafish hepatocytes at single-cell resolution.
By Faraz Ahmed Butt, Alessandro De Simone, Stefano Di Talia, Kenneth Poss
tinyurl.com/ve5vzp6c
A new powerful live imaging platform tracks Erk signalling dynamics in developing zebrafish hepatocytes at single-cell resolution.
By Faraz Ahmed Butt, Alessandro De Simone, Stefano Di Talia, Kenneth Poss
tinyurl.com/ve5vzp6c
November 25, 2025 at 12:35 PM
#DBfeature 🐠
A new powerful live imaging platform tracks Erk signalling dynamics in developing zebrafish hepatocytes at single-cell resolution.
By Faraz Ahmed Butt, Alessandro De Simone, Stefano Di Talia, Kenneth Poss
tinyurl.com/ve5vzp6c
A new powerful live imaging platform tracks Erk signalling dynamics in developing zebrafish hepatocytes at single-cell resolution.
By Faraz Ahmed Butt, Alessandro De Simone, Stefano Di Talia, Kenneth Poss
tinyurl.com/ve5vzp6c
Reposted by Rocky Diegmiller
#FlatironCCB researchers and collaborators demonstrated how mechanical forces from surrounding tissues can shape the fruit fly gut: https://www.simonsfoundation.org/2025/11/17/from-ring-to-keyhole-modeling-how-tissues-mold-the-fruit-flys-gut/ #science #biology
From Ring to Keyhole: Modeling How Tissues Mold the Fruit Fly’s Gut
A study on the fruit fly gut led by Flatiron Institute researchers gives insight into how tissues are shaped by bumping into their neighbors.
www.simonsfoundation.org
November 25, 2025 at 2:20 PM
#FlatironCCB researchers and collaborators demonstrated how mechanical forces from surrounding tissues can shape the fruit fly gut: https://www.simonsfoundation.org/2025/11/17/from-ring-to-keyhole-modeling-how-tissues-mold-the-fruit-flys-gut/ #science #biology
Reposted by Rocky Diegmiller
@sushantbangru.bsky.social and @rdiegmiller.bsky.social new review on regeneration is out in Nature Reviews Molecular Cell Biology. A fun piece to write and another great collaboration with @kenposs.bsky.social.
New Online! Signal control during tissue regeneration in adult animals
Signal control during tissue regeneration in adult animals
Nature Reviews Molecular Cell Biology, Published online: 11 November 2025; doi:10.1038/s41580-025-00917-1The ability to track single cells in vivo, combined with insights into chromatin structure, immune–tissue crosstalk, bioelectric and metabolic cues and quantitative modelling, is changing our understanding of how tissues are repaired and renewed. This Review discusses how signals are regulated during regeneration and future directions for a more quantitative understanding of regenerative biology.
bit.ly
November 13, 2025 at 8:48 PM
@sushantbangru.bsky.social and @rdiegmiller.bsky.social new review on regeneration is out in Nature Reviews Molecular Cell Biology. A fun piece to write and another great collaboration with @kenposs.bsky.social.
Reposted by Rocky Diegmiller
New Online! Signal control during tissue regeneration in adult animals
Signal control during tissue regeneration in adult animals
Nature Reviews Molecular Cell Biology, Published online: 11 November 2025; doi:10.1038/s41580-025-00917-1The ability to track single cells in vivo, combined with insights into chromatin structure, immune–tissue crosstalk, bioelectric and metabolic cues and quantitative modelling, is changing our understanding of how tissues are repaired and renewed. This Review discusses how signals are regulated during regeneration and future directions for a more quantitative understanding of regenerative biology.
bit.ly
November 11, 2025 at 6:04 PM
New Online! Signal control during tissue regeneration in adult animals
Reposted by Rocky Diegmiller
Reposted by Rocky Diegmiller
"We're doing the studies to make the proof."
This is not how Gold Standard Science works. Or any science. You do the study to TEST THE HYPOTHESIS, not to prove yourself right.
This is not how Gold Standard Science works. Or any science. You do the study to TEST THE HYPOTHESIS, not to prove yourself right.
RFK Jr on Tylenol and autism: "It is not proof. We're doing the studies to make the proof."
October 9, 2025 at 6:41 PM
"We're doing the studies to make the proof."
This is not how Gold Standard Science works. Or any science. You do the study to TEST THE HYPOTHESIS, not to prove yourself right.
This is not how Gold Standard Science works. Or any science. You do the study to TEST THE HYPOTHESIS, not to prove yourself right.
Reposted by Rocky Diegmiller
UPenn professors have responded forcefully to the Trump administration's that colleges sign a "compact" in order to secure funding:
"When an invitation is accompanied by consequences for not accepting it, it is in fact a threat, not an invitation." aaup-penn.org/statement-by...
"When an invitation is accompanied by consequences for not accepting it, it is in fact a threat, not an invitation." aaup-penn.org/statement-by...
Statement by the AAUP-Penn Executive Committee on the Compact for Academic Excellence in Higher Education | AAUP–Penn
October 2, 2025 We have received reports that Penn has been “invited” to sign a so-called “Compact for Academic Excellence in Higher Education” by the federal government, and that failing to do so wou...
aaup-penn.org
October 2, 2025 at 5:27 PM
UPenn professors have responded forcefully to the Trump administration's that colleges sign a "compact" in order to secure funding:
"When an invitation is accompanied by consequences for not accepting it, it is in fact a threat, not an invitation." aaup-penn.org/statement-by...
"When an invitation is accompanied by consequences for not accepting it, it is in fact a threat, not an invitation." aaup-penn.org/statement-by...
Reposted by Rocky Diegmiller
Reposted by Rocky Diegmiller
Reposted by Rocky Diegmiller
Thrilled to share our work using live imaging to understand how Epiblast (future embryo proper) and Primitive Endoderm (future extraembryonic tissues) cell fates segregate in the preimplantation mouse embryo. Gargantuan effort led by amazing @rpkimyip.bsky.social, David Denberg and Denis Faerberg!
August 2, 2025 at 7:31 PM
Thrilled to share our work using live imaging to understand how Epiblast (future embryo proper) and Primitive Endoderm (future extraembryonic tissues) cell fates segregate in the preimplantation mouse embryo. Gargantuan effort led by amazing @rpkimyip.bsky.social, David Denberg and Denis Faerberg!
Reposted by Rocky Diegmiller
STUDY: Denmark tracked over a million children for 21 years, and found vaccines linked to zero extra cases of autism, asthma, or 48 other conditions.
Vaccines are safe, effective, and the best way to eradicate preventable disease. Period.
Vaccines are safe, effective, and the best way to eradicate preventable disease. Period.
July 28, 2025 at 1:56 PM
STUDY: Denmark tracked over a million children for 21 years, and found vaccines linked to zero extra cases of autism, asthma, or 48 other conditions.
Vaccines are safe, effective, and the best way to eradicate preventable disease. Period.
Vaccines are safe, effective, and the best way to eradicate preventable disease. Period.
Reposted by Rocky Diegmiller
I was having lunch with an NSF program manager when her cell phone lit up, all with messages about the overhead rate.
We won! The United States District Court for the District of Massachusetts said NSF can't reduce the overhead rate to 15% for universities! 🥳
cases.justia.com/federal/dist...
We won! The United States District Court for the District of Massachusetts said NSF can't reduce the overhead rate to 15% for universities! 🥳
cases.justia.com/federal/dist...
June 23, 2025 at 6:30 PM
I was having lunch with an NSF program manager when her cell phone lit up, all with messages about the overhead rate.
We won! The United States District Court for the District of Massachusetts said NSF can't reduce the overhead rate to 15% for universities! 🥳
cases.justia.com/federal/dist...
We won! The United States District Court for the District of Massachusetts said NSF can't reduce the overhead rate to 15% for universities! 🥳
cases.justia.com/federal/dist...
Reposted by Rocky Diegmiller
Published in the Wheeling Intelligencer this week as part of the #McClintockLetters
www.theintelligencer.net/opinion/loca...
www.theintelligencer.net/opinion/loca...
June 23, 2025 at 11:06 PM
Published in the Wheeling Intelligencer this week as part of the #McClintockLetters
www.theintelligencer.net/opinion/loca...
www.theintelligencer.net/opinion/loca...
Happy to see the article I wrote in print back home! Thankful for the McClintock Letters organizers (@cornellasap.bsky.social) and Science Homecoming (@sciencehomecoming.bsky.social) for all their hard work in coordinating this effort.
Science Funding Cuts Affect Our Present and Future
Zebrafish are cool. They’re just one of a handful of animals that can regenerate their brain, spine, and even heart after injury. Unsurprisingly, a lot can be learned from studying how these injured o...
www.theintelligencer.net
June 14, 2025 at 11:07 AM
Happy to see the article I wrote in print back home! Thankful for the McClintock Letters organizers (@cornellasap.bsky.social) and Science Homecoming (@sciencehomecoming.bsky.social) for all their hard work in coordinating this effort.
Reposted by Rocky Diegmiller
Harvard is everything now. There is no next round. We're all Harvard.
May 27, 2025 at 5:41 PM
Harvard is everything now. There is no next round. We're all Harvard.
Reposted by Rocky Diegmiller
Make no mistake. This is an extinction level event for American scientific dominance.
May 27, 2025 at 5:38 PM
Make no mistake. This is an extinction level event for American scientific dominance.
Reposted by Rocky Diegmiller
Reposted by Rocky Diegmiller
Delighted that our work on positional memory is now published. We asked how axolotl cells 'know' which part of the limb to regenerate after injury.
www.nature.com/articles/s41...
A joy to work with super team Sarah Plattner, Yuka Sugiura, Francisco Falcon and Elly Tanaka.
🧵1/14
www.nature.com/articles/s41...
A joy to work with super team Sarah Plattner, Yuka Sugiura, Francisco Falcon and Elly Tanaka.
🧵1/14
May 21, 2025 at 3:05 PM
Delighted that our work on positional memory is now published. We asked how axolotl cells 'know' which part of the limb to regenerate after injury.
www.nature.com/articles/s41...
A joy to work with super team Sarah Plattner, Yuka Sugiura, Francisco Falcon and Elly Tanaka.
🧵1/14
www.nature.com/articles/s41...
A joy to work with super team Sarah Plattner, Yuka Sugiura, Francisco Falcon and Elly Tanaka.
🧵1/14
Reposted by Rocky Diegmiller
As someone directly affected by this, let me be clear:
I'd rather lose my job because Harvard chose to fight than keep my job and see a generation of white supremacists parade its corpse around like a war trophy.
I'd rather lose my job because Harvard chose to fight than keep my job and see a generation of white supremacists parade its corpse around like a war trophy.
Researchers at Harvard and its affiliates appreciate that the university resisted the Trump Administration's demands, but worry about what happens next.
At Harvard, scientists worry over the consequences of resisting the Trump administration: $2.2B in grants frozen
Researchers at Harvard and its affiliates appreciate that the university resisted the Trump Administration's demands, but worry about what happens next.
buff.ly
April 15, 2025 at 4:29 PM
As someone directly affected by this, let me be clear:
I'd rather lose my job because Harvard chose to fight than keep my job and see a generation of white supremacists parade its corpse around like a war trophy.
I'd rather lose my job because Harvard chose to fight than keep my job and see a generation of white supremacists parade its corpse around like a war trophy.
Reposted by Rocky Diegmiller
For transporting us beyond Seas to be tried for pretended offences
April 14, 2025 at 4:42 PM
For transporting us beyond Seas to be tried for pretended offences
Reposted by Rocky Diegmiller
Injury-induced electrochemical coupling triggers regenerative cell proliferation https://www.biorxiv.org/content/10.1101/2025.04.03.647033v1
April 8, 2025 at 10:47 PM
Injury-induced electrochemical coupling triggers regenerative cell proliferation https://www.biorxiv.org/content/10.1101/2025.04.03.647033v1
Reposted by Rocky Diegmiller
This is a shocking lack of courage from Stanford.
Stanford is allowing Bhattacharya to go emeritus instead of calling him out—for all he got wrong on COVID and for all the rank garbage he wrote in rightwing sites from Epoch Times to NYPost Opinion.
Stanford will own the damage to NIH that he does.
Stanford is allowing Bhattacharya to go emeritus instead of calling him out—for all he got wrong on COVID and for all the rank garbage he wrote in rightwing sites from Epoch Times to NYPost Opinion.
Stanford will own the damage to NIH that he does.
March 22, 2025 at 4:32 PM
This is a shocking lack of courage from Stanford.
Stanford is allowing Bhattacharya to go emeritus instead of calling him out—for all he got wrong on COVID and for all the rank garbage he wrote in rightwing sites from Epoch Times to NYPost Opinion.
Stanford will own the damage to NIH that he does.
Stanford is allowing Bhattacharya to go emeritus instead of calling him out—for all he got wrong on COVID and for all the rank garbage he wrote in rightwing sites from Epoch Times to NYPost Opinion.
Stanford will own the damage to NIH that he does.
Awesome work just published! Certainly wouldn’t have been possible without the incredible support and dashing good looks of the first author’s significant other
Epithelial polarization by the planar cell polarity complex is exclusively non–cell autonomous
For cells to polarize collectively along a tissue plane, asymmetrically localized planar cell polarity (PCP) complexes must form intercellular contacts between neighboring cells. Yet, it is unknown wh...
www.science.org
March 20, 2025 at 11:45 PM
Awesome work just published! Certainly wouldn’t have been possible without the incredible support and dashing good looks of the first author’s significant other