Otavio Ranzani
@otavioranzani.bsky.social
Group Leader - DataHealth Lab
Global Health | Epidemiology | RCTs
Critical Care, Infections, Climate Change
#DecolonizeGH 🇧🇷
At IR Sant Pau, Barcelona / USP, São Paulo
https://datahealthlab.org
Global Health | Epidemiology | RCTs
Critical Care, Infections, Climate Change
#DecolonizeGH 🇧🇷
At IR Sant Pau, Barcelona / USP, São Paulo
https://datahealthlab.org
🚨 The Interim Report of the Global Climate and Health Summit is out!
Please, read, share and connect with us. The second phase is open
Honoured to be a Vice-Chair of this Summit
www.physoc.org/policy/clima...
Please, read, share and connect with us. The second phase is open
Honoured to be a Vice-Chair of this Summit
www.physoc.org/policy/clima...
Global Climate and Health Summit
The 2025 Global Climate and Health Summit placed physiology and partnerships at the heart of climate and health. Read more
www.physoc.org
November 9, 2025 at 9:47 PM
🚨 The Interim Report of the Global Climate and Health Summit is out!
Please, read, share and connect with us. The second phase is open
Honoured to be a Vice-Chair of this Summit
www.physoc.org/policy/clima...
Please, read, share and connect with us. The second phase is open
Honoured to be a Vice-Chair of this Summit
www.physoc.org/policy/clima...
Reposted by Otavio Ranzani
📚 Development and Validation of the Sequential Organ Failure Assessment (SOFA)-2 Score:
Presented today in the #LIVES2025 Hot Topics session.
🔗 Free to read online: ja.ma/4qzouAz
Presented today in the #LIVES2025 Hot Topics session.
🔗 Free to read online: ja.ma/4qzouAz
October 29, 2025 at 1:15 PM
📚 Development and Validation of the Sequential Organ Failure Assessment (SOFA)-2 Score:
Presented today in the #LIVES2025 Hot Topics session.
🔗 Free to read online: ja.ma/4qzouAz
Presented today in the #LIVES2025 Hot Topics session.
🔗 Free to read online: ja.ma/4qzouAz
Reposted by Otavio Ranzani
📚 Rationale and Methodological Approach Underlying the Development of the Sequential Organ Failure Assessment (SOFA)–2 Score: A Consensus Statement:
📣 Presented today in the #LIVES2025 Hot Topics session.
➡️ Free to read online:
ja.ma/42ZZZ5B
📣 Presented today in the #LIVES2025 Hot Topics session.
➡️ Free to read online:
ja.ma/42ZZZ5B
October 29, 2025 at 2:15 PM
📚 Rationale and Methodological Approach Underlying the Development of the Sequential Organ Failure Assessment (SOFA)–2 Score: A Consensus Statement:
📣 Presented today in the #LIVES2025 Hot Topics session.
➡️ Free to read online:
ja.ma/42ZZZ5B
📣 Presented today in the #LIVES2025 Hot Topics session.
➡️ Free to read online:
ja.ma/42ZZZ5B
Reposted by Otavio Ranzani
Development and Validation of the Sequential Organ Failure Assessment (SOFA)-2 Score.
Ranzani OT, Singer M, Salluh JIF, et al.
JAMA. Published online October 29, 2025. jamanetwork.com/journals/jam...
Ranzani OT, Singer M, Salluh JIF, et al.
JAMA. Published online October 29, 2025. jamanetwork.com/journals/jam...
Development and Validation of the SOFA-2 Score
This article describes the data-driven development and validation of the final SOFA-2 score.
jamanetwork.com
October 29, 2025 at 3:55 PM
Development and Validation of the Sequential Organ Failure Assessment (SOFA)-2 Score.
Ranzani OT, Singer M, Salluh JIF, et al.
JAMA. Published online October 29, 2025. jamanetwork.com/journals/jam...
Ranzani OT, Singer M, Salluh JIF, et al.
JAMA. Published online October 29, 2025. jamanetwork.com/journals/jam...
That single slide that make the difference 😅
When I delete slide 137 from my presentation because I might run out of time
October 30, 2025 at 8:01 AM
That single slide that make the difference 😅
Reposted by Otavio Ranzani
In this episode of the JAMA Author Interviews podcast, coauthor Mervyn Singer, MD, discusses the development and validation of the Sequential Organ Failure Assessment (SOFA)-2 score with JAMA Associate Editor Christopher Seymour, MD, MSc.
🎧 Listen now:
ja.ma/47wiUX0
🎧 Listen now:
ja.ma/47wiUX0
https://ja.ma/4oJNbst
JAMA Author Interviews
ja.ma
October 29, 2025 at 2:00 PM
In this episode of the JAMA Author Interviews podcast, coauthor Mervyn Singer, MD, discusses the development and validation of the Sequential Organ Failure Assessment (SOFA)-2 score with JAMA Associate Editor Christopher Seymour, MD, MSc.
🎧 Listen now:
ja.ma/47wiUX0
🎧 Listen now:
ja.ma/47wiUX0
Reposted by Otavio Ranzani
From @jamanetworkopen.com: The SOFA-2 score updates the 1996 Sequential Organ Failure Assessment, reflecting current definitions, variables, and thresholds to grade organ dysfunction in critically ill adults receiving intensive care.
#LIVES2025 @esicm.bsky.social
ja.ma/3JuguA7
#LIVES2025 @esicm.bsky.social
ja.ma/3JuguA7
October 29, 2025 at 1:15 PM
From @jamanetworkopen.com: The SOFA-2 score updates the 1996 Sequential Organ Failure Assessment, reflecting current definitions, variables, and thresholds to grade organ dysfunction in critically ill adults receiving intensive care.
#LIVES2025 @esicm.bsky.social
ja.ma/3JuguA7
#LIVES2025 @esicm.bsky.social
ja.ma/3JuguA7
Reposted by Otavio Ranzani
💬 Editorial: SOFA-2 improves the measurement of organ failure in intensive care by integrating current treatments and data-driven criteria, but further research is needed to address persistent challenges and optimize bedside utility.
#LIVES2025 @esicm.bsky.social
ja.ma/47pxgZb
#LIVES2025 @esicm.bsky.social
ja.ma/47pxgZb
October 29, 2025 at 1:10 PM
💬 Editorial: SOFA-2 improves the measurement of organ failure in intensive care by integrating current treatments and data-driven criteria, but further research is needed to address persistent challenges and optimize bedside utility.
#LIVES2025 @esicm.bsky.social
ja.ma/47pxgZb
#LIVES2025 @esicm.bsky.social
ja.ma/47pxgZb
Reposted by Otavio Ranzani
SOFA-2, validated in >3 million ICU patients, incorporates contemporary organ support and treatments, showing strong predictive validity for ICU mortality in diverse international settings.
#LIVES2025 @esicm.bsky.social
ja.ma/4hE2H70
#LIVES2025 @esicm.bsky.social
ja.ma/4hE2H70
October 29, 2025 at 1:05 PM
SOFA-2, validated in >3 million ICU patients, incorporates contemporary organ support and treatments, showing strong predictive validity for ICU mortality in diverse international settings.
#LIVES2025 @esicm.bsky.social
ja.ma/4hE2H70
#LIVES2025 @esicm.bsky.social
ja.ma/4hE2H70
hahaha
When researchers bring up confounders without ever having declared the actual analysis goal
October 28, 2025 at 11:32 PM
hahaha
Good point! Let’s revive the tradition: if you recently read an interesting paper (doesn’t matter which field) please share!! #FridayPaperClub
@odedrechavi.bsky.social What happened to paper Fridays?
October 24, 2025 at 11:40 PM
Looking forward to see these trial results
There are now just under 50 days to CCR Down Under 2025.
The programme is out - 8 superb trial results coming up.
Join us in Melbourne, in person or virtually, to discuss the best critical care trials in the world!
criticalcarereviews.com/meetings/ccr...
The programme is out - 8 superb trial results coming up.
Join us in Melbourne, in person or virtually, to discuss the best critical care trials in the world!
criticalcarereviews.com/meetings/ccr...
October 22, 2025 at 7:25 AM
Looking forward to see these trial results
Reposted by Otavio Ranzani
The 8th & final trial for CCR Down Under is ECMO Rehab
➡️100-patient RCT testing early mobilisation during ECMO to reduce 6-month disability
➡️Will mobilisation improve outcomes?
Join us in Melbourne, December 9/10
criticalcarereviews.com/meetings/ccr...
➡️100-patient RCT testing early mobilisation during ECMO to reduce 6-month disability
➡️Will mobilisation improve outcomes?
Join us in Melbourne, December 9/10
criticalcarereviews.com/meetings/ccr...
CCR Down Under 2025
Critical Care Reviews Meeting Down Under - The Edge, Federation Square, Melbourne, December 9th - 10th, 2025
criticalcarereviews.com
October 14, 2025 at 6:33 PM
The 8th & final trial for CCR Down Under is ECMO Rehab
➡️100-patient RCT testing early mobilisation during ECMO to reduce 6-month disability
➡️Will mobilisation improve outcomes?
Join us in Melbourne, December 9/10
criticalcarereviews.com/meetings/ccr...
➡️100-patient RCT testing early mobilisation during ECMO to reduce 6-month disability
➡️Will mobilisation improve outcomes?
Join us in Melbourne, December 9/10
criticalcarereviews.com/meetings/ccr...
Reposted by Otavio Ranzani
Still want to make cleaning biodiversity data shrimp-ler? 🦐
Good news: We just updated our Cleaning Biodiversity Data in R book, so you still can! We've updated data for 2025, added new content & fixed lots of silly typos 😀
Live the shrimp-le life:
cleaning-data-r.ala.org.au
#rstats #ecology 🧪🌏
Good news: We just updated our Cleaning Biodiversity Data in R book, so you still can! We've updated data for 2025, added new content & fixed lots of silly typos 😀
Live the shrimp-le life:
cleaning-data-r.ala.org.au
#rstats #ecology 🧪🌏
October 15, 2025 at 4:12 AM
Still want to make cleaning biodiversity data shrimp-ler? 🦐
Good news: We just updated our Cleaning Biodiversity Data in R book, so you still can! We've updated data for 2025, added new content & fixed lots of silly typos 😀
Live the shrimp-le life:
cleaning-data-r.ala.org.au
#rstats #ecology 🧪🌏
Good news: We just updated our Cleaning Biodiversity Data in R book, so you still can! We've updated data for 2025, added new content & fixed lots of silly typos 😀
Live the shrimp-le life:
cleaning-data-r.ala.org.au
#rstats #ecology 🧪🌏
Reposted by Otavio Ranzani
Looks like a good guide - the general data cleaning part is a lean intro to some very common issues in all sorts of data. Would be great if every phd who touches raw data was offered a short course in these basics (in R or Python or whatever HipsterScript) cleaning-data-r.ala.org.au/2_general-cl...
October 15, 2025 at 9:44 AM
Looks like a good guide - the general data cleaning part is a lean intro to some very common issues in all sorts of data. Would be great if every phd who touches raw data was offered a short course in these basics (in R or Python or whatever HipsterScript) cleaning-data-r.ala.org.au/2_general-cl...
Reposted by Otavio Ranzani
In >1,100 high-risk surgical patients, individualized periop BP targets based on pre-op nocturnal MAP were not associated with ↓ kidney or cardiac injury vs routine MAP ≥65 mm Hg
CCR Journal Watch – tracking the critical care literature daily
criticalcarereviews.com/latest-evide...
CCR Journal Watch – tracking the critical care literature daily
criticalcarereviews.com/latest-evide...
October 12, 2025 at 4:24 PM
In >1,100 high-risk surgical patients, individualized periop BP targets based on pre-op nocturnal MAP were not associated with ↓ kidney or cardiac injury vs routine MAP ≥65 mm Hg
CCR Journal Watch – tracking the critical care literature daily
criticalcarereviews.com/latest-evide...
CCR Journal Watch – tracking the critical care literature daily
criticalcarereviews.com/latest-evide...
Reposted by Otavio Ranzani
😂
Just saw a post which misspelled 'Machine learning' as 'Machine earning', and I wondered if that was a Freudian slip.
October 9, 2025 at 10:03 PM
😂
😂😂🤣🗣
That is true
That is true
Academics take one headshot at the start of their career and then use it for the next 40 years.
October 6, 2025 at 9:27 PM
😂😂🤣🗣
That is true
That is true
Reposted by Otavio Ranzani
A great and informative discussion of peer review. I have too many opinions to go into depth here.
My general solution is to better value, in all senses, both peer and editorial review. If peer review was formally counted as work by an academic that might encourage more engagement.
My general solution is to better value, in all senses, both peer and editorial review. If peer review was formally counted as work by an academic that might encourage more engagement.
🎙️ Just published: Communicable E37: 'Peer review is broken'
Hosted by @angelahuttner.bsky.social & @anniejoseph.bsky.social
w/ invited guests: Melinda Baldwin @mbaldwin.bsky.social & Serge Horbach
Listen on Communicable:
#IDSky #Clinmicro #MedSky #peerreview #AI
Hosted by @angelahuttner.bsky.social & @anniejoseph.bsky.social
w/ invited guests: Melinda Baldwin @mbaldwin.bsky.social & Serge Horbach
Listen on Communicable:
#IDSky #Clinmicro #MedSky #peerreview #AI
Communicable E37: 'Peer review is broken'
Contrary to popular belief, peer review has only recently become an...
share.transistor.fm
October 6, 2025 at 5:28 PM
A great and informative discussion of peer review. I have too many opinions to go into depth here.
My general solution is to better value, in all senses, both peer and editorial review. If peer review was formally counted as work by an academic that might encourage more engagement.
My general solution is to better value, in all senses, both peer and editorial review. If peer review was formally counted as work by an academic that might encourage more engagement.
Reposted by Otavio Ranzani
Any cancer epidemiologists looking for a tenure track position? We (Dept of Epi at USF) are hiring. Happy to share more info if you’re interested 😊
October 6, 2025 at 9:09 PM
Any cancer epidemiologists looking for a tenure track position? We (Dept of Epi at USF) are hiring. Happy to share more info if you’re interested 😊
Reposted by Otavio Ranzani
NEW Research: Non-invasive high frequency oscillatory ventilation for primary respiratory support in extremely preterm infants: multicentre randomised controlled trial
Read here: www.bmj.com/content/391/...
Read here: www.bmj.com/content/391/...
October 6, 2025 at 4:01 PM
NEW Research: Non-invasive high frequency oscillatory ventilation for primary respiratory support in extremely preterm infants: multicentre randomised controlled trial
Read here: www.bmj.com/content/391/...
Read here: www.bmj.com/content/391/...
Reposted by Otavio Ranzani
jornal.usp.br/artigos/a-ex...
Meu comentário sobre o recém-lançado livro da Rossana Soleti, cientista, professora e coordenadora do Parent in Science.
Meu comentário sobre o recém-lançado livro da Rossana Soleti, cientista, professora e coordenadora do Parent in Science.
A extraordinária ciência da gestação
Por Luiza Caires, jornalista e editora de Ciências do Jornal da USP
jornal.usp.br
October 2, 2025 at 10:37 PM
jornal.usp.br/artigos/a-ex...
Meu comentário sobre o recém-lançado livro da Rossana Soleti, cientista, professora e coordenadora do Parent in Science.
Meu comentário sobre o recém-lançado livro da Rossana Soleti, cientista, professora e coordenadora do Parent in Science.
Decolonize Science
A collection of fossils that helped change our understanding of humanity’s origins is itself going back to its origin. https://scim.ag/4mHHVUM
‘Thrilled’ Indonesian scientists celebrate return of fossil trove from the Netherlands
The items to be returned, which include Java Man, were collected during the colonial era
scim.ag
October 2, 2025 at 1:53 PM
Decolonize Science