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Critical Care Reviews
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Critical care evidence dissemination - science for all.
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Today's Paper of the Day is:

Lipid Emulsion to Treat Acute Poisonings: Mechanisms of Action, Indications, and Controversies

https://criticalcarereviews.com/latest-evidence/paper-of-the-day

Join us to read 1 paper per day and stay up-to-date as we cover the spectrum of critical care across 2025
December 15, 2025 at 11:39 AM
Today's Paper of the Day is:

Examining the threat of H5N1 highly pathogenic avian influenza to human health

https://criticalcarereviews.com/latest-evidence/paper-of-the-day

Join us to read 1 paper per day and stay up-to-date as we cover the spectrum of critical care across 2025
December 14, 2025 at 12:07 PM
Current Pharmacological and Non-Pharmacological Decongestion Strategies in Acute Heart Failure - Evidence and Practical Guidance

CCR Journal Watch
https://criticalcarereviews.com/latest-evidence/journal-watch
December 13, 2025 at 12:15 PM
Extracorporeal Membrane Oxygenation in Acute Cardiovascular Care

CCR Journal Watch
https://criticalcarereviews.com/latest-evidence/journal-watch
December 13, 2025 at 12:14 PM
The role of catecholamines in aneurysmal subarachnoid hemorrhage: a narrative review

CCR Journal Watch
https://criticalcarereviews.com/latest-evidence/journal-watch
December 13, 2025 at 12:11 PM
Today's Paper of the Day is:

Imaging the Lung in ARDS: A Primer

https://criticalcarereviews.com/latest-evidence/paper-of-the-day

Join us to read 1 paper per day and stay up-to-date as we cover the spectrum of critical care across 2025
December 13, 2025 at 11:20 AM
Today's Paper of the Day is:

Out-of-Hospital Cardiac Arrest in Apparently Healthy, Young Adults

https://criticalcarereviews.com/latest-evidence/paper-of-the-day

Join us to read 1 paper per day and stay up-to-date as we cover the spectrum of critical care across 2025
December 12, 2025 at 9:56 AM
Today's Paper of the Day is:

Cardiac surgery-associated acute kidney injury

https://criticalcarereviews.com/latest-evidence/paper-of-the-day

Join us to read 1 paper per day and stay up-to-date as we cover the spectrum of critical care across 2025
December 11, 2025 at 2:01 PM
Modulation of the Renin–Angiotensin System in Critically Ill Patients: Addressing Seven Key Questions for the Intensivist

CCR Journal Watch
https://criticalcarereviews.com/latest-evidence/journal-watch
December 11, 2025 at 7:08 AM
Current standard of care for septic shock

CCR Journal Watch
https://criticalcarereviews.com/latest-evidence/journal-watch
December 11, 2025 at 7:07 AM
Our Journal Watch feature has been quiet for a couple of weeks, due to CCR Down Under.

Normal service resumes!

Acute Right Ventricular Failure in the Medical ICU

CCR Journal Watch
https://criticalcarereviews.com/latest-evidence/journal-watch
December 11, 2025 at 7:02 AM
Reposted by Critical Care Reviews
Had a great time sitting on the panels for #RSI and #CLIPII at #CCRDownunder and it was great to see my Monash statto pals on stage @jesskasza.bsky.social @criticalcarereviews.com
December 10, 2025 at 10:16 PM
Reposted by Critical Care Reviews
Casey and the PRAGMATIC trial group do excellent trials. 3 years to recruit 2365 pts, complete the trial and publish. Recruited 70% of pts screened. Well oiled machine. @criticalcarereviews.com
Ketamine or Etomidate for Tracheal Intubation of Critically Ill Adults | NEJM
For critically ill adults undergoing tracheal intubation, observational studies suggest that the use of etomidate to induce anesthesia may increase the risk of death. Whether the use of ketamine ra...
www.nejm.org
December 10, 2025 at 6:37 AM
Today's Paper of the Day is:

Techniques for improvement of success rate in ultrasound-guided radial artery catheterization

criticalcarereviews.com/latest-evide...

Join us to read 1 paper per day and stay up-to-date as we cover the spectrum of critical care across 2025
December 10, 2025 at 11:19 AM
Co-Chief Investigators Carol Hodgson and Lisa Higgins share an overview of the #ECMORehab trial and the key takeaways for clinicians after presenting the results at #CCRdownunder

@jama.com
December 10, 2025 at 7:21 AM
Chief Investigator Angelique de Man and Senior Investigator Sander Rozemeijer share the results from the #VITaCCA trial and what it means for clinicians after presenting at #CCRdownunder

Livestream -> www.criticalcarereviews.com

@jama.com
December 10, 2025 at 5:52 AM
Co-Chief Investigators Jonathan Casey and Matthew Semler share their insights from the #RSI trial after presenting at #CCRdownunder

Livestream -> www.criticalcarereviews.com

@jama.com
December 10, 2025 at 5:40 AM
Chief Investigator Arthur Kwizera shares an overview of the #ARISEAFRICA trial after presenting at #CCRdownunder and highlights what clinicians can take away from the results.

Livestream -> www.criticalcarereviews.com

@jama.com
December 10, 2025 at 4:40 AM
Reposted by Critical Care Reviews
#ARISEAFRICAtrial is a stepped wedge cluster- this design is useful for interventions delivered at the ICU/hospital level and individual randomisation is difficult. Clusters transition from control to intervention at different times www.bmj.com/content/350/... #ccrdownunder @criticalcarereviews.com
The stepped wedge cluster randomised trial: rationale, design, analysis, and reporting
#### Summary points
www.bmj.com
December 9, 2025 at 10:14 PM
Reposted by Critical Care Reviews
In a randomized trial involving critically ill patients undergoing intubation in EDs or ICUs, the use of ketamine for the induction of anesthesia did not lead to significantly lower in-hospital mortality than etomidate. Full trial results: nej.md/44EOlxB

@criticalcarereviews.com
December 10, 2025 at 12:20 AM
Reposted by Critical Care Reviews
Wow wow wow

Beautiful trial. Nice editorial. Worth watching if you intubate patients.
RSI trial now starting

➡️ Etomidate vs Ketamine for RSI

➡️ Jonathan Casey & Matthew Semler presenting
➡️ Chris Nickson editorialising

➡️ Join the livestream - criticalcarereviews.com

#ccrdownunder
December 10, 2025 at 12:47 AM
RSI trial now starting

➡️ Etomidate vs Ketamine for RSI

➡️ Jonathan Casey & Matthew Semler presenting
➡️ Chris Nickson editorialising

➡️ Join the livestream - criticalcarereviews.com

#ccrdownunder
December 10, 2025 at 12:14 AM
Today's Paper of the Day is:

Reversal of antithrombotic medications in patients with traumatic brain injury: what you need to know

criticalcarereviews.com/latest-evide...

Join us to read 1 paper per day and stay up-to-date as we cover the spectrum of critical care across 2025
December 9, 2025 at 1:40 PM
Chief Investigator Ary Serpa Neto shares an overview of the #ACTiVE trial after presenting the results at #CCRdownunder

@jama.com
December 9, 2025 at 7:41 AM
Chief Investigator Michael Reade provides an overview of the #CLIP-II trial at #CCRdownunder and what it means for clinicians.

@jama.com
December 9, 2025 at 7:34 AM