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Critical Care Reviews @criticalcarereviews.com · 2m

CCR Down Under 2025

➡️ Where critical care’s biggest trials are presented, discussed and disseminated
➡️ 8 major trials on the programme

Join us in Melbourne, in person or virtually
https://criticalcarereviews.com/meetings/ccr-down-under-2025

CCR Down Under 2025

Critical Care Reviews Meeting Down Under - The Edge, Federation Square, Melbourne, December 9th - 10th, 2025

criticalcarereviews.com

Critical Care Reviews @criticalcarereviews.com · 3h

Where does the fluid go?

➡️ Excess crystalloid pools in skin, gut and lungs
➡️ Rapid ~1.3–1.5 L opens a slow-exchange third space that traps fluid

CCR Journal Watch
criticalcarereviews.com/latest-evide...

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Critical Care Reviews @criticalcarereviews.com · 3h

Optimal antibiotic use in the ICU

➡️ Early antibiotics save lives, but overuse drives resistance
➡️ Rapid diagnostics, PK/PD dosing & early de-escalation are key to ICU stewardship
➡️ Smarter use today protects antibiotics for tomorrow

CCR Journal Watch
criticalcarereviews.com/latest-evide...

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Critical Care Reviews @criticalcarereviews.com · 9h

Today's Paper of the Day is:

Post-extubation dysphagia in the ICU−a narrative review: epidemiology, mechanisms and clinical management

criticalcarereviews.com/latest-evide...

Join us to read 1 paper per day and stay up-to-date as we cover the spectrum of critical care across 2025

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Critical Care Reviews @criticalcarereviews.com · 1d

The 8th & final trial for CCR Down Under is ECMO Rehab

➡️100-patient RCT testing early mobilisation during ECMO to reduce 6-month disability
➡️Will mobilisation improve outcomes?

Join us in Melbourne, December 9/10
criticalcarereviews.com/meetings/ccr...

CCR Down Under 2025

Critical Care Reviews Meeting Down Under - The Edge, Federation Square, Melbourne, December 9th - 10th, 2025

criticalcarereviews.com

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Critical Care Reviews @criticalcarereviews.com · 1d

Today's Paper of the Day is:

Transfusion in trauma: empiric or guided therapy?

https://criticalcarereviews.com/latest-evidence/paper-of-the-day

Join us to read 1 paper per day and stay up-to-date as we cover the spectrum of critical care across 2025

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Critical Care Reviews @criticalcarereviews.com · 1d

A special issue from Critical Care Resuscitation Journal honouring the legacy of Rinaldo Bellomo

Grab a coffee, sit back, read and smile.

Such an incredible person.

An uplifting tribute.

Kudos to the authors for sharing their experiences

www.sciencedirect.com/journal/crit...

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Critical Care Reviews @criticalcarereviews.com · 2d

➡️ Pediatric myocarditis is more often viral and acute, adults more chronic and immune-mediated
➡️ Diagnosis and treatment draw from adult data, leaving major gaps in paediatric evidence

CCR Journal Watch - tracking the critical care literature daily
criticalcarereviews.com/latest-evide...

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Critical Care Reviews @criticalcarereviews.com · 2d

➡️ Topical analgesics provide strong pain relief with minimal systemic exposure
➡️ Lidocaine, NSAIDs & capsaicin help musculoskeletal and neuropathic pain yet remain underused

CCR Journal Watch - tracking the critical care literature daily
criticalcarereviews.com/latest-evide...

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Critical Care Reviews @criticalcarereviews.com · 2d

Traumatic Brain Injury: Advances in Diagnostic Techniques and Treatment Modalities

CCR Journal Watch - tracking the critical care literature daily
https://criticalcarereviews.com/latest-evidence/journal-watch

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Critical Care Reviews @criticalcarereviews.com · 2d

➡️ Three major RCTs (HEMOTION, TRAIN, SAHaRA) challenge restrictive transfusion dogma in brain injury.
➡️ Does the evidence now points toward a more liberal, neuroprotective threshold?

CCR Journal Watch
https://criticalcarereviews.com/latest-evidence/journal-watch

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Critical Care Reviews @criticalcarereviews.com · 2d

Today's Paper of the Day is:

Hypophosphataemia in Critical Illness

https://criticalcarereviews.com/latest-evidence/paper-of-the-day

Join us to read 1 paper per day and stay up-to-date as we cover the spectrum of critical care across 2025

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Critical Care Reviews @criticalcarereviews.com · 3d

In >1,100 high-risk surgical patients, individualized periop BP targets based on pre-op nocturnal MAP were not associated with ↓ kidney or cardiac injury vs routine MAP ≥65 mm Hg

CCR Journal Watch – tracking the critical care literature daily
criticalcarereviews.com/latest-evide...

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Critical Care Reviews @criticalcarereviews.com · 3d

In >3,200 adults undergoing noncardiac surgery, stratified intraop BP targets based on hypotension risk were not associated with ↓ functional disability at 6 months vs standard management

CCR Journal Watch – tracking the critical care literature daily
criticalcarereviews.com/latest-evide...

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Critical Care Reviews @criticalcarereviews.com · 3d

Among >10,000 ventilated adults, deeper sedation was associated with ↑ risk of death or loss of independence, while lighter sedation with mobility was associated with ↓ risk.

CCR Journal Watch – tracking the critical care literature daily

criticalcarereviews.com/latest-evide...

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Critical Care Reviews @criticalcarereviews.com · 3d

Today's Paper of the Day is:

A Comprehensive Review of Catheter-Related Thrombosis

https://criticalcarereviews.com/latest-evidence/paper-of-the-day

Join us to read 1 paper per day and stay up-to-date as we cover the spectrum of critical care across 2025

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Critical Care Reviews @criticalcarereviews.com · 4d

Communicating to Patients and Families About Post-Intensive Care Syndrome

CCR Journal Watch - tracking the critical care literature daily
https://criticalcarereviews.com/latest-evidence/journal-watch

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Critical Care Reviews @criticalcarereviews.com · 4d

Postoperative pseudomembranous colitis after abdominal surgery: pathogenesis, diagnosis and current management

CCR Journal Watch - tracking the critical care literature daily
https://criticalcarereviews.com/latest-evidence/journal-watch

Critical Care Reviews @criticalcarereviews.com · 4d

Acute Myocardial Infarction: Molecular Pathogenesis, Diagnosis, and Clinical Management

CCR Journal Watch - tracking the critical care literature daily
https://criticalcarereviews.com/latest-evidence/journal-watch

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Critical Care Reviews @criticalcarereviews.com · 4d

Today's Paper of the Day is:

Confronting heatstroke: Understanding, preventing and treating a deadly condition

https://criticalcarereviews.com/latest-evidence/paper-of-the-day

Join us to read 1 paper per day and stay up-to-date as we cover the spectrum of critical care across 2025

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Critical Care Reviews @criticalcarereviews.com · 5d

Today's Paper of the Day is:

Multimodal and autoregulation monitoring in the neurointensive care unit

https://criticalcarereviews.com/latest-evidence/paper-of-the-day

Join us to read 1 paper per day and stay up-to-date as we cover the spectrum of critical care across 2025

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Critical Care Reviews @criticalcarereviews.com · 6d

The use of CytoSorb hemoadsorption in critically ill patients

CCR Journal Watch - tracking the critical care literature daily
https://criticalcarereviews.com/latest-evidence/journal-watch

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Critical Care Reviews @criticalcarereviews.com · 6d

Ventilator-induced diaphragmatic dysfunction: pathophysiology, monitoring and advances in potential treatment and prevention

CCR Journal Watch
https://criticalcarereviews.com/latest-evidence/journal-watch

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Critical Care Reviews @criticalcarereviews.com · 6d

Management and monitoring strategies for severe cerebral malaria: a guide for the intensivist

CCR Journal Watch
https://criticalcarereviews.com/latest-evidence/journal-watch

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Critical Care Reviews @criticalcarereviews.com · 6d

Today's Paper of the Day is:

Multidisciplinary management of tracheobronchial injury

https://criticalcarereviews.com/latest-evidence/paper-of-the-day

Join us to read 1 paper per day and stay up-to-date as we cover the spectrum of critical care across 2025

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