Dr. Fiona
@fionachembot.bsky.social
she/her; I use computers to study chemistry! Junior Professor in the Institute of Physical Chemistry at Albert-Ludwigs Universität Freiburg!
Pinned
Dr. Fiona
@fionachembot.bsky.social
· Mar 13
D614G reshapes allosteric networks and opening mechanisms of SARS-CoV-2 spikes
The SARS-CoV-2 spike glycoprotein binds human epithelial cells and enables infection through a key conformational transition that exposes its receptor binding domain (RBD). Experimental evidence indic...
www.biorxiv.org
Nevertheless, we persisted ❤️
📣 NEW BIORXIV ALERT!! 🚨
Using WE MD, linguistic pathway clustering, dynamical network analyses, and HDXMS we reveal a hidden allosteric network within the SARS2 spike S1 domain and predict how the D614G mutation impacts this network!
www.biorxiv.org/content/10.1...
📣 NEW BIORXIV ALERT!! 🚨
Using WE MD, linguistic pathway clustering, dynamical network analyses, and HDXMS we reveal a hidden allosteric network within the SARS2 spike S1 domain and predict how the D614G mutation impacts this network!
www.biorxiv.org/content/10.1...
this week on NPR's tiny desk concert
my tiny desk breakdown
my tiny desk breakdown
November 25, 2025 at 7:56 PM
this week on NPR's tiny desk concert
my tiny desk breakdown
my tiny desk breakdown
spoken like a true wise one
November 24, 2025 at 5:04 PM
spoken like a true wise one
Ask not how many tabs you can have open,
But ask how many tabs you can have open per window
But ask how many tabs you can have open per window
November 24, 2025 at 3:45 PM
Ask not how many tabs you can have open,
But ask how many tabs you can have open per window
But ask how many tabs you can have open per window
Reposted by Dr. Fiona
Just a friendly reminder as we go into the holidays:
Folks don't have to explain to you why they don't drink.
If you offer them a drink and they decline, don't ask them why. It's not your business.
Just offer them something without alcohol to drink instead. And move on.
Folks don't have to explain to you why they don't drink.
If you offer them a drink and they decline, don't ask them why. It's not your business.
Just offer them something without alcohol to drink instead. And move on.
November 23, 2025 at 8:04 PM
Just a friendly reminder as we go into the holidays:
Folks don't have to explain to you why they don't drink.
If you offer them a drink and they decline, don't ask them why. It's not your business.
Just offer them something without alcohol to drink instead. And move on.
Folks don't have to explain to you why they don't drink.
If you offer them a drink and they decline, don't ask them why. It's not your business.
Just offer them something without alcohol to drink instead. And move on.
Reposted by Dr. Fiona
Supramolecular Carbohydrate Assemblies with Tunable Glycan Surfaces out today in @angewandtechemie.bsky.social!
Congrats to Nives, Marlene, Junki, Jaap, Kai, Yu, and Katharina!
@mpici.bsky.social
onlinelibrary.wiley.com/doi/10.1002/...
Congrats to Nives, Marlene, Junki, Jaap, Kai, Yu, and Katharina!
@mpici.bsky.social
onlinelibrary.wiley.com/doi/10.1002/...
Supramolecular Carbohydrate Assemblies with Tunable Glycan Surfaces
Synthetic cellulose-based oligomers assemble into supramolecular nanomaterials with a molecularly controlled, dense presentation of carbohydrates on their surfaces, serving as biological cues.
onlinelibrary.wiley.com
November 24, 2025 at 8:09 AM
Supramolecular Carbohydrate Assemblies with Tunable Glycan Surfaces out today in @angewandtechemie.bsky.social!
Congrats to Nives, Marlene, Junki, Jaap, Kai, Yu, and Katharina!
@mpici.bsky.social
onlinelibrary.wiley.com/doi/10.1002/...
Congrats to Nives, Marlene, Junki, Jaap, Kai, Yu, and Katharina!
@mpici.bsky.social
onlinelibrary.wiley.com/doi/10.1002/...
Now I'm falling asleep and she's calling a cab
While he's having a smoke and she's taking a drag
Now they're goin' to bed and my stomach is sick
And it's all in my head, but she's touching his
While he's having a smoke and she's taking a drag
Now they're goin' to bed and my stomach is sick
And it's all in my head, but she's touching his
Vomit on his sweater already
Mom's spaghetti
Mom's spaghetti
November 23, 2025 at 12:33 PM
Now I'm falling asleep and she's calling a cab
While he's having a smoke and she's taking a drag
Now they're goin' to bed and my stomach is sick
And it's all in my head, but she's touching his
While he's having a smoke and she's taking a drag
Now they're goin' to bed and my stomach is sick
And it's all in my head, but she's touching his
Meet my friend Nick Riley!!
Know an inspiring early-career chemist? Nominate an early-career chemist for the 2026 Talented 12 at cen.acs.org/sections/tal...
Submit your nomination by January 20, 2026.
#CENT12 #MassSpec #Chemistry
Submit your nomination by January 20, 2026.
#CENT12 #MassSpec #Chemistry
November 21, 2025 at 4:31 PM
Meet my friend Nick Riley!!
Reposted by Dr. Fiona
Sun-dappled lemon shark 🔮🌈🌞🍋🦈🪸🌇 #lemonshark #sharksofcoralcity #shark #rainbow #dappled #sunlight #coral #coralhead #coralcitycamera #miami #portmiami #miamibeach #biscaynebay #bridgeinitiative #bfi #noaa #aoml #coralcity
November 21, 2025 at 3:31 PM
Sun-dappled lemon shark 🔮🌈🌞🍋🦈🪸🌇 #lemonshark #sharksofcoralcity #shark #rainbow #dappled #sunlight #coral #coralhead #coralcitycamera #miami #portmiami #miamibeach #biscaynebay #bridgeinitiative #bfi #noaa #aoml #coralcity
In today's lesson on cognitive bias
Grok pronounces Elon Musk as the greatest genius in all of human history... whereas analysts who have studied him suggest his IQ is only slightly above normal and certainly not at the genius or near genius level. www.independent.co.uk/news/world/a...
Elon Musk’s AI chatbot Grok ranks him as world history’s greatest human
Grok suggested Elon Musk was more fit than LeBron James
www.independent.co.uk
November 21, 2025 at 3:32 PM
In today's lesson on cognitive bias
Reposted by Dr. Fiona
"Ecology without class struggle is just gardening" (Chico Mendes)
You ever just sit down and realize that the rise of 21st century fascism is capital's answer to climate change?
November 21, 2025 at 12:43 PM
"Ecology without class struggle is just gardening" (Chico Mendes)
Grant writing be like:
a man and an older woman are standing in front of a sign that says ' gibson amber '
Alt: charlie kelly and his mom standing on a stage, charlies mom is reading a paper that says "Give me money. Money me. Money now. Me a money needing a lot now"
media.tenor.com
November 21, 2025 at 11:48 AM
Grant writing be like:
Law of Conservation of Matter be damned!!!
November 19, 2025 at 4:33 PM
Law of Conservation of Matter be damned!!!
Reposted by Dr. Fiona
Academia is a really racist and sexist place. Larry Summers, as the president of Harvard, epitomized that racism and sexism but he is not unique. That's why we needed DEI.
November 18, 2025 at 3:48 PM
Academia is a really racist and sexist place. Larry Summers, as the president of Harvard, epitomized that racism and sexism but he is not unique. That's why we needed DEI.
Might as well name his next rocket "Icarus" while he's at it
Literally the subtitle to Mary Shelley’s “Frankenstein.”
November 17, 2025 at 9:43 PM
Might as well name his next rocket "Icarus" while he's at it
lets all be whistle blowers
“Short bursts indicate an ICE sighting. Long whistles indicate agents making arrests. If you hear the whistle and you’re undocumented, said [Whitney Hu, a community activist and organizer with South Brooklyn Mutual Aid], ‘you hide. And if you’re somebody who’s not, you go to the street.’”
As ICE Street Raids Ramp Up, New Yorkers Stock Up On Whistles
Taking a cue from Chicago, community groups have distributed thousands of whistles in recent weeks — a grassroots system people in other cities have adopted to help neighbors sound the alarm.
www.thecity.nyc
November 17, 2025 at 9:26 PM
lets all be whistle blowers
Reposted by Dr. Fiona
Dont give my German teacher any ideas now
I am the ghost of Christmas Future Perfect Subjunctive; I will show you what would have happened were you not to have changed your ways.
November 17, 2025 at 12:29 PM
Dont give my German teacher any ideas now
Are you a postdoc stuck in the US?! Is your research stalled or are you in any way affected by the whims of that unfettered madman? Interested in MD simulations of large biomolecules?!
Consider joining me at the University of Freiburg!
uni-freiburg.de/frias/call-f...
Consider joining me at the University of Freiburg!
uni-freiburg.de/frias/call-f...
Call for Applications: Early Career Rescue Fellowship – Freiburg Institute for Advanced Studies
uni-freiburg.de
November 17, 2025 at 8:51 AM
Are you a postdoc stuck in the US?! Is your research stalled or are you in any way affected by the whims of that unfettered madman? Interested in MD simulations of large biomolecules?!
Consider joining me at the University of Freiburg!
uni-freiburg.de/frias/call-f...
Consider joining me at the University of Freiburg!
uni-freiburg.de/frias/call-f...
Reposted by Dr. Fiona
"Postdoc in the job market"
November 16, 2025 at 7:52 PM
"Postdoc in the job market"
What strikes me about the Summers-Epstein emails?
Young women in science often walk away from exchanges thinking "did he mean it like that? he probably is just from a different time"
anddd nope. they know what they are saying, why they are saying it, and they are achieving their intended impact.
Young women in science often walk away from exchanges thinking "did he mean it like that? he probably is just from a different time"
anddd nope. they know what they are saying, why they are saying it, and they are achieving their intended impact.
November 16, 2025 at 3:31 PM
What strikes me about the Summers-Epstein emails?
Young women in science often walk away from exchanges thinking "did he mean it like that? he probably is just from a different time"
anddd nope. they know what they are saying, why they are saying it, and they are achieving their intended impact.
Young women in science often walk away from exchanges thinking "did he mean it like that? he probably is just from a different time"
anddd nope. they know what they are saying, why they are saying it, and they are achieving their intended impact.
Reposted by Dr. Fiona
I can reassure the New York Times that networks of mutual protection, and misogynist retaliation efforts that benefit abusive men at the expense of the young women they prey upon, are very much still intact post-Me Too.
This is nauseating: “As the emails stretch through the years, they show how that protected realm vanished into the mists of time, pulled under by the rising forces of the internet and the #MeToo movement.” A “Gone With the Wind” framing for sexual abuse and harassment.
Seriously, what is wrong with these people?
November 16, 2025 at 2:13 PM
I can reassure the New York Times that networks of mutual protection, and misogynist retaliation efforts that benefit abusive men at the expense of the young women they prey upon, are very much still intact post-Me Too.
lets check in with my feelings of imposter syndrome since starting my new position as a junior prof:
November 14, 2025 at 8:47 PM
lets check in with my feelings of imposter syndrome since starting my new position as a junior prof:
This. this is what i will be doing for the rest of time.
Me, wisely: "But *his* emails"
November 13, 2025 at 2:16 PM
This. this is what i will be doing for the rest of time.