Mike Ando
@dmikeando.bsky.social
ML @ Calico. Previously at Google Research and UCSF. Still amazed and excited by the power of microscopy to understand biology.
Pinned
Mike Ando
@dmikeando.bsky.social
· Nov 22
There has been enough interest that we are on to Microscopy Starter Pack #2. Still open to who to include, including yourself!
go.bsky.app/DA4LAjJ
go.bsky.app/DA4LAjJ
Reposted by Mike Ando
Good ML code comes from people who fundamentally believe that ML is a trickster god and wants them to fail
November 24, 2025 at 3:20 AM
Good ML code comes from people who fundamentally believe that ML is a trickster god and wants them to fail
Reposted by Mike Ando
New release of the TrackMate single particle tracking plugin for ImageJ by @jytinevez.bsky.social looks amazing! forum.image.sc/t/trackmate-...
Loads of new features, most excitingly to me deep learning segmentation algorithms including Omnipose (for cells), and Spotiflow (for spots) #bioimaging
Loads of new features, most excitingly to me deep learning segmentation algorithms including Omnipose (for cells), and Spotiflow (for spots) #bioimaging
TrackMate v8 - segmentation editor and Python CLI integration
TrackMate v8: 2D Segmentation Editor & Python CLI Integration Hi everyone, I am excited to announce TrackMate v8, a major update introducing key improvements for both end-users and developers. Mai...
forum.image.sc
November 24, 2025 at 2:14 PM
New release of the TrackMate single particle tracking plugin for ImageJ by @jytinevez.bsky.social looks amazing! forum.image.sc/t/trackmate-...
Loads of new features, most excitingly to me deep learning segmentation algorithms including Omnipose (for cells), and Spotiflow (for spots) #bioimaging
Loads of new features, most excitingly to me deep learning segmentation algorithms including Omnipose (for cells), and Spotiflow (for spots) #bioimaging
Reposted by Mike Ando
Thank you editors for improving the readability of our paper by removing acronyms. Now we grow our cluster of differentiation 4+ Forkhead box 3+ cells in Roswell Park Memorial Institute media with phorbol 12-myristate 13-acetate.
TIL, RPMI media is actually Roswell Park Memorial Institute media
TIL, RPMI media is actually Roswell Park Memorial Institute media
November 22, 2025 at 11:57 AM
Thank you editors for improving the readability of our paper by removing acronyms. Now we grow our cluster of differentiation 4+ Forkhead box 3+ cells in Roswell Park Memorial Institute media with phorbol 12-myristate 13-acetate.
TIL, RPMI media is actually Roswell Park Memorial Institute media
TIL, RPMI media is actually Roswell Park Memorial Institute media
Reposted by Mike Ando
We present Olmo 3, our next family of fully open, leading language models.
This family of 7B and 32B models represents:
1. The best 32B base model.
2. The best 7B Western thinking & instruct models.
3. The first 32B (or larger) fully open reasoning model.
This family of 7B and 32B models represents:
1. The best 32B base model.
2. The best 7B Western thinking & instruct models.
3. The first 32B (or larger) fully open reasoning model.
November 20, 2025 at 2:32 PM
We present Olmo 3, our next family of fully open, leading language models.
This family of 7B and 32B models represents:
1. The best 32B base model.
2. The best 7B Western thinking & instruct models.
3. The first 32B (or larger) fully open reasoning model.
This family of 7B and 32B models represents:
1. The best 32B base model.
2. The best 7B Western thinking & instruct models.
3. The first 32B (or larger) fully open reasoning model.
Reposted by Mike Ando
@ninaluong.bsky.social is really upping her costume game this year. And she can still work in it!
October 31, 2025 at 3:21 PM
@ninaluong.bsky.social is really upping her costume game this year. And she can still work in it!
Reposted by Mike Ando
When #halloween meets #FluorescenceFriday 🎃
October 31, 2025 at 4:21 PM
When #halloween meets #FluorescenceFriday 🎃
Reposted by Mike Ando
🎃A fluorescent turmeric jack-o'-lantern!🎃
I filled a flat-bottom flask with turmeric extract. Jordan Tanen drew the face.🖊️ #FluorescenceFriday #SciArt #SciComm #RealTimeChem #ChemArt
I filled a flat-bottom flask with turmeric extract. Jordan Tanen drew the face.🖊️ #FluorescenceFriday #SciArt #SciComm #RealTimeChem #ChemArt
October 24, 2025 at 1:00 PM
🎃A fluorescent turmeric jack-o'-lantern!🎃
I filled a flat-bottom flask with turmeric extract. Jordan Tanen drew the face.🖊️ #FluorescenceFriday #SciArt #SciComm #RealTimeChem #ChemArt
I filled a flat-bottom flask with turmeric extract. Jordan Tanen drew the face.🖊️ #FluorescenceFriday #SciArt #SciComm #RealTimeChem #ChemArt
Reposted by Mike Ando
The #OME-Zarr RFC-5 proposal allows you to transform multiple images into the same coordinateSystem. Trying this out with napari at github.com/will-moore/n.... Cool that you can offset T-dimension as well as XYZ!
October 20, 2025 at 1:00 PM
The #OME-Zarr RFC-5 proposal allows you to transform multiple images into the same coordinateSystem. Trying this out with napari at github.com/will-moore/n.... Cool that you can offset T-dimension as well as XYZ!
Reposted by Mike Ando
🎃Welcome to my fluorescent pumpkin patch!🎃
Jack-O-Lanterns are pipette tips filled with 😈 lucifer yellow, fluorescein, or rhodamine 101.🎃
🌝 #FluorescenceFriday #PipetteArt #SciArt #ChemArt #SciComm #HappyHalloween #Halloween 🎃
Jack-O-Lanterns are pipette tips filled with 😈 lucifer yellow, fluorescein, or rhodamine 101.🎃
🌝 #FluorescenceFriday #PipetteArt #SciArt #ChemArt #SciComm #HappyHalloween #Halloween 🎃
October 17, 2025 at 12:38 PM
🎃Welcome to my fluorescent pumpkin patch!🎃
Jack-O-Lanterns are pipette tips filled with 😈 lucifer yellow, fluorescein, or rhodamine 101.🎃
🌝 #FluorescenceFriday #PipetteArt #SciArt #ChemArt #SciComm #HappyHalloween #Halloween 🎃
Jack-O-Lanterns are pipette tips filled with 😈 lucifer yellow, fluorescein, or rhodamine 101.🎃
🌝 #FluorescenceFriday #PipetteArt #SciArt #ChemArt #SciComm #HappyHalloween #Halloween 🎃
Reposted by Mike Ando
New #NeurIPS2025 paper: how should we evaluate machine learning models without a large, labeled dataset? We introduce Semi-Supervised Model Evaluation (SSME), which uses labeled and unlabeled data to estimate performance! We find SSME is far more accurate than standard methods.
October 17, 2025 at 4:29 PM
New #NeurIPS2025 paper: how should we evaluate machine learning models without a large, labeled dataset? We introduce Semi-Supervised Model Evaluation (SSME), which uses labeled and unlabeled data to estimate performance! We find SSME is far more accurate than standard methods.
Reposted by Mike Ando
Going through some Erdős problems that Mark Sellke and Mehtaab Sawhney found had already been solved using GPT5 pro for search. More precisely, these were listed as open, but solutions to them already existed in the literature, but not recognized as such. Quite remarkable.
One example: [+]
One example: [+]
October 18, 2025 at 5:17 AM
Going through some Erdős problems that Mark Sellke and Mehtaab Sawhney found had already been solved using GPT5 pro for search. More precisely, these were listed as open, but solutions to them already existed in the literature, but not recognized as such. Quite remarkable.
One example: [+]
One example: [+]
Reposted by Mike Ando
For this #FluorescenceFriday 🔬
a cryosection of a dissected zebrafish gill, stained with phalloidin (orange) and DAPI (blue-ish).
#Zebrafish #DevBio #Microscopy
a cryosection of a dissected zebrafish gill, stained with phalloidin (orange) and DAPI (blue-ish).
#Zebrafish #DevBio #Microscopy
October 17, 2025 at 3:15 PM
For this #FluorescenceFriday 🔬
a cryosection of a dissected zebrafish gill, stained with phalloidin (orange) and DAPI (blue-ish).
#Zebrafish #DevBio #Microscopy
a cryosection of a dissected zebrafish gill, stained with phalloidin (orange) and DAPI (blue-ish).
#Zebrafish #DevBio #Microscopy
Reposted by Mike Ando
what do you mean i have to submit an abstract now for a presentation in april?
October 18, 2025 at 2:27 PM
what do you mean i have to submit an abstract now for a presentation in april?
Reposted by Mike Ando
Today for #FluorescenceFriday I’m sharing a 👻Halloween-themed🎃 neural crest explant “web of cells” from Julia Godinez, a 4th year @ucdavis.bsky.social graduate student in the lab. She is studying mechanisms driving conserved and divergent cranial neural crest migration and differentiation. #DevBio
October 17, 2025 at 8:21 PM
Today for #FluorescenceFriday I’m sharing a 👻Halloween-themed🎃 neural crest explant “web of cells” from Julia Godinez, a 4th year @ucdavis.bsky.social graduate student in the lab. She is studying mechanisms driving conserved and divergent cranial neural crest migration and differentiation. #DevBio
Reposted by Mike Ando
As part of our monthly meeting, we do a run-down of all* the new #bioimageanalysis tools that have been published in the last couple of weeks on BioRxiv**, so I thought I'd start sharing here as well.
*I will miss some, apologies if I miss your paper
*I will miss some, apologies if I miss your paper
October 17, 2025 at 7:17 AM
As part of our monthly meeting, we do a run-down of all* the new #bioimageanalysis tools that have been published in the last couple of weeks on BioRxiv**, so I thought I'd start sharing here as well.
*I will miss some, apologies if I miss your paper
*I will miss some, apologies if I miss your paper
Reposted by Mike Ando
Stages of CV research work
1. Denial
2. Anger
3. Bargaining
4. Depression
5. Manual data labeling
6. ???
7. PROFIT
1. Denial
2. Anger
3. Bargaining
4. Depression
5. Manual data labeling
6. ???
7. PROFIT
October 15, 2025 at 3:41 PM
Stages of CV research work
1. Denial
2. Anger
3. Bargaining
4. Depression
5. Manual data labeling
6. ???
7. PROFIT
1. Denial
2. Anger
3. Bargaining
4. Depression
5. Manual data labeling
6. ???
7. PROFIT
Reposted by Mike Ando
Big news! Our week-long #bioimageanalysis bootcamp is BACK! Learn how to think about bioimage analysis like the pros do, learn what corrections you should (and shouldn't!) apply to your images, learn open source tools, and more. Apply NOW at broad.io/BAB3 for our January 2026 course!
October 14, 2025 at 9:31 PM
Big news! Our week-long #bioimageanalysis bootcamp is BACK! Learn how to think about bioimage analysis like the pros do, learn what corrections you should (and shouldn't!) apply to your images, learn open source tools, and more. Apply NOW at broad.io/BAB3 for our January 2026 course!
Reposted by Mike Ando
I found these immune cells just finished mitosis but their midbody is still yet to be resolved. How cool? If you zoom in to the midbody, you can see its classical shape just like in the textbooks. I love these little details.
October 14, 2025 at 10:56 AM
I found these immune cells just finished mitosis but their midbody is still yet to be resolved. How cool? If you zoom in to the midbody, you can see its classical shape just like in the textbooks. I love these little details.
Reposted by Mike Ando
The future of High-Content Imaging has arrived.
-> Ultra-fast 3D imaging of multi-well plates at high resolution using an air objective!
See previous posts and the new miOPM preprint for details: doi.org/10.1101/2025...
-> Ultra-fast 3D imaging of multi-well plates at high resolution using an air objective!
See previous posts and the new miOPM preprint for details: doi.org/10.1101/2025...
October 13, 2025 at 12:44 AM
The future of High-Content Imaging has arrived.
-> Ultra-fast 3D imaging of multi-well plates at high resolution using an air objective!
See previous posts and the new miOPM preprint for details: doi.org/10.1101/2025...
-> Ultra-fast 3D imaging of multi-well plates at high resolution using an air objective!
See previous posts and the new miOPM preprint for details: doi.org/10.1101/2025...
Reposted by Mike Ando
Threw away the pellet
In honour of spooky month, share a 4 word horror story that only someone in your profession would understand.
rm -rf ~/
rm -rf ~/
"The chancellor approved it"
October 12, 2025 at 1:26 PM
Threw away the pellet
Reposted by Mike Ando
#SpatialOmics
MCMICRO
Multiple Choice Microscopy pipeline
mcmicro.org
Multi-channel whole-slide images▶️
Single-cell data + Spatial Feature Tables
Multimodal (CyCIF CODEX mIHC) registration + HE IMC MIBI
#NatMethods 2022
www.nature.com/articles/s41...
MCMICRO
Multiple Choice Microscopy pipeline
mcmicro.org
Multi-channel whole-slide images▶️
Single-cell data + Spatial Feature Tables
Multimodal (CyCIF CODEX mIHC) registration + HE IMC MIBI
#NatMethods 2022
www.nature.com/articles/s41...
October 12, 2025 at 12:21 PM
#SpatialOmics
MCMICRO
Multiple Choice Microscopy pipeline
mcmicro.org
Multi-channel whole-slide images▶️
Single-cell data + Spatial Feature Tables
Multimodal (CyCIF CODEX mIHC) registration + HE IMC MIBI
#NatMethods 2022
www.nature.com/articles/s41...
MCMICRO
Multiple Choice Microscopy pipeline
mcmicro.org
Multi-channel whole-slide images▶️
Single-cell data + Spatial Feature Tables
Multimodal (CyCIF CODEX mIHC) registration + HE IMC MIBI
#NatMethods 2022
www.nature.com/articles/s41...
Reposted by Mike Ando
The connectome of the entire male Drosophila central nervous system is out!! Acquired using FIB-SEM @ 8x8x8nm, we aligned 7.5 mio 2D images aligned into one seamless 3D volume, which was used to segment & proofread neurons and synapses. @hhmijanelia.bsky.social
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
October 11, 2025 at 1:30 PM
The connectome of the entire male Drosophila central nervous system is out!! Acquired using FIB-SEM @ 8x8x8nm, we aligned 7.5 mio 2D images aligned into one seamless 3D volume, which was used to segment & proofread neurons and synapses. @hhmijanelia.bsky.social
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
Reposted by Mike Ando
Happy #FluorescenceFriday! Our #CellLineOfTheWeek is Nucleoporin Nup153! 🧫
Our stem cell lines and plasmids, illuminating specific cell structures, are available for just the cost of shipping to support scientific discovery.
📦 Distributed by @coriellinstitute.bsky.social & @addgene.bsky.social
Our stem cell lines and plasmids, illuminating specific cell structures, are available for just the cost of shipping to support scientific discovery.
📦 Distributed by @coriellinstitute.bsky.social & @addgene.bsky.social
October 10, 2025 at 9:52 PM
Happy #FluorescenceFriday! Our #CellLineOfTheWeek is Nucleoporin Nup153! 🧫
Our stem cell lines and plasmids, illuminating specific cell structures, are available for just the cost of shipping to support scientific discovery.
📦 Distributed by @coriellinstitute.bsky.social & @addgene.bsky.social
Our stem cell lines and plasmids, illuminating specific cell structures, are available for just the cost of shipping to support scientific discovery.
📦 Distributed by @coriellinstitute.bsky.social & @addgene.bsky.social
Reposted by Mike Ando
For #FluorescenceFriday, α-spectrin (red) and lipid droplets (green) are shown in adipocytes 🔬 #Microscopy #CellBiology
October 10, 2025 at 6:37 PM
For #FluorescenceFriday, α-spectrin (red) and lipid droplets (green) are shown in adipocytes 🔬 #Microscopy #CellBiology