Adrian Liston
@labliston.bsky.social
5.5K followers 3.9K following 640 posts
Professor of Pathology at the University of Cambridge. Equalities Fellow, Welfare Tutor and Director-of-Studies at St Catharine's College. Educator, scientist, immunologist, daddy. Founder and CSO of Aila Biotech Ltd.
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labliston.bsky.social
Then racism is not a natural state.
labliston.bsky.social
You think that kids have an innate fear response against strangers *based on race*?
labliston.bsky.social
We notoriously have to *teach* “stranger danger” to kids, because it isn’t intrinsic
labliston.bsky.social
Shockingly bad pseudo-science
labliston.bsky.social
No, I don’t think so. I see children being taught racism, not children being born racist

But then my philosophy is to never attribute to genes something that already has an established environmental cause, unless the data compels me to
labliston.bsky.social
I see what you are saying, but I think the genetics analogy is most unhelpful. It plays into the narrative that it is the natural state of things, and also cannot be changed.
Reposted by Adrian Liston
becherlab.bsky.social
Exciting new data from the lab - check it out!🔥
Reposted by Adrian Liston
hkoohy.bsky.social
Highly motivated and talented candidates are strongly encouraged to apply
labliston.bsky.social
You’re right! There was actually a ton of great pre-Foxp3 work going on, before Tregs went mainstream
labliston.bsky.social
Enormous loss. Vale John Gurdon.
jamesbriscoe.bsky.social
Very sad news, John Gurdon has died.

A developmental biologist's developmental biologist, Nobel prize winner

His work is the foundation of much of today's dev & stem cell bio.

An inspiration to many, including me. Always asking questions & wanting the answers

www.magd.cam.ac.uk/news/profess...
Professor Sir John Gurdon FRS (1933-2025) | Magdalene College
Magdalene College is deeply saddened to announce the death of Professor Sir John Gurdon FRS, who served as Master of the College from 1995 to 2002.
www.magd.cam.ac.uk
Reposted by Adrian Liston
tuurekinnunen.bsky.social
Yes, Tregs finally getting the spotlight they deserve! 🙌
labliston.bsky.social
A small primer on the #NobelPrize awarded to Mary E. Brunkow, Fred Ramsdell and Shimon Sakaguchi today. This prize was for combining two separate fields of immunology research - genetic research on IPEX and immunology research of regulatory T cells (#Tregs), with enormous impact on biology/medicine
Reposted by Adrian Liston
ryanlab.bsky.social
Check out a lovely bitesize historical perspective from Adrian below.
labliston.bsky.social
A small primer on the #NobelPrize awarded to Mary E. Brunkow, Fred Ramsdell and Shimon Sakaguchi today. This prize was for combining two separate fields of immunology research - genetic research on IPEX and immunology research of regulatory T cells (#Tregs), with enormous impact on biology/medicine
Reposted by Adrian Liston
labliston.bsky.social
A small primer on the #NobelPrize awarded to Mary E. Brunkow, Fred Ramsdell and Shimon Sakaguchi today. This prize was for combining two separate fields of immunology research - genetic research on IPEX and immunology research of regulatory T cells (#Tregs), with enormous impact on biology/medicine
labliston.bsky.social
Along with Sasha Rudensky, one of the other giants of the field, who did his key Treg work at UW! Seattle was at the epicentre of the Treg world!
labliston.bsky.social
Yep! 2003 were the key papers. Things changed really fast!
Reposted by Adrian Liston
cp-trendsgenetics.bsky.social
Today's Nobel Prize announcement was a win for the field of genetics as well. Congrats to all involved!
labliston.bsky.social
In 2003, the key breakthrough happened - groups lead by Sakaguchi, Ramsdell and Sasha Rudensky all demonstrated that FOXP3, the IPEX gene, was also the master transcription factor that made Tregs immunosuppressive. Suddenly everyone could study Tregs and manipulate their genetics.
Reposted by Adrian Liston
kallikourdis.bsky.social
I've had Sakaguchi papers on my desk since '99, when I was warned against studying cells (Treg) that may not exist. 26 years on, we've shown you need them to reproduce and we may bring them to Heart clinics. A joyous overdue toast to Sakaguchi's steadfast building of the foundations of our science!
labliston.bsky.social
A small primer on the #NobelPrize awarded to Mary E. Brunkow, Fred Ramsdell and Shimon Sakaguchi today. This prize was for combining two separate fields of immunology research - genetic research on IPEX and immunology research of regulatory T cells (#Tregs), with enormous impact on biology/medicine
Reposted by Adrian Liston
immuninjas.bsky.social
Congratulations! #NobelPrize #Tregi
Reposted by Adrian Liston
dudakov-lab.bsky.social
Great primer. Also great to see peripheral tolerance recognized, but I will note you can’t get tregs without central tolerance and the thymus! Miller snubbed again!
labliston.bsky.social
A small primer on the #NobelPrize awarded to Mary E. Brunkow, Fred Ramsdell and Shimon Sakaguchi today. This prize was for combining two separate fields of immunology research - genetic research on IPEX and immunology research of regulatory T cells (#Tregs), with enormous impact on biology/medicine
labliston.bsky.social
The thymus needs its own Nobel Prize, not a shared one with Tregs!
Reposted by Adrian Liston
jgcastillo.bsky.social
Great to see Tregs win a Nobel prize!!
labliston.bsky.social
A small primer on the #NobelPrize awarded to Mary E. Brunkow, Fred Ramsdell and Shimon Sakaguchi today. This prize was for combining two separate fields of immunology research - genetic research on IPEX and immunology research of regulatory T cells (#Tregs), with enormous impact on biology/medicine
Reposted by Adrian Liston
mfrosch.bsky.social
Great recap of the story and the breakthroughs behind the 2025 #NobelPrize in Physiology or Medicine! 🏅🏅🏅
labliston.bsky.social
A small primer on the #NobelPrize awarded to Mary E. Brunkow, Fred Ramsdell and Shimon Sakaguchi today. This prize was for combining two separate fields of immunology research - genetic research on IPEX and immunology research of regulatory T cells (#Tregs), with enormous impact on biology/medicine
Reposted by Adrian Liston
okolupaev.bsky.social
This summary is exactly what you need to know about todays Nobel prize winners and their contributions to our understanding of the immune system
labliston.bsky.social
A small primer on the #NobelPrize awarded to Mary E. Brunkow, Fred Ramsdell and Shimon Sakaguchi today. This prize was for combining two separate fields of immunology research - genetic research on IPEX and immunology research of regulatory T cells (#Tregs), with enormous impact on biology/medicine