Small-molecule drug discovery has transitioned from traditional phenotypic screening to more precise target-based approaches, with an increased focus on understanding mechanisms of action (MoA) and ta...

This study shows that deep-learning-based co-folding models often produce physically unrealistic structures and are unsusceptible in their predictions to significant binding site modifications, demonstrating bias towards training data and underscoring the need for stronger integration of physical principles.

ALT: a close up of a man 's face with the word interesting written below him

Magdalene College is deeply saddened to announce the death of Professor Sir John Gurdon FRS, who served as Master of the College from 1995 to 2002.

A research team has successfully sequenced a near-complete bird flu genome aboard a ship in Antarctic waters, proving that portable lab equipment can generate critical information about viral threats…