@dholmes.bsky.social
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Academics vying for a spot in Epstein‘s world. There are so many. I feel the need to make a thread, so I don’t keep confusing them. 1/
February 5, 2026 at 2:04 AM
🧵
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I keep thinking again, in light of the latest Epstein files dump, about how MeToo “went too far.”
January 31, 2026 at 3:43 PM
I keep thinking again, in light of the latest Epstein files dump, about how MeToo “went too far.”
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"We're going to make sure your neighbors know you're heroes"
TOM HOMAN: “We’re going to create a database where those people that are arrested for interference, impeding and assault, we’re going to make them famous. We’re going to put their face on TV. We’re going to let their employers, in their neighborhoods, in their schools, know who these people are.”
Story: www.cnn.com/2026/01/27/u...
January 27, 2026 at 7:53 PM
"We're going to make sure your neighbors know you're heroes"
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In response to announcement that he will be a new CBS contributor, Andrew Huberman tweeted “I’ve always gone issue-by-issue on health & science, spoken to experts w/a range of takes & presented where I see the center of (data) mass pointed. I’ll do the same with @CBSNews”. In Sept he posted this:
January 28, 2026 at 1:44 AM
In response to announcement that he will be a new CBS contributor, Andrew Huberman tweeted “I’ve always gone issue-by-issue on health & science, spoken to experts w/a range of takes & presented where I see the center of (data) mass pointed. I’ll do the same with @CBSNews”. In Sept he posted this:
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If you’re a grown ass man in full tactical gear asking a child to show you ID or proof of citizenship you failed at life. Utterly & completely failed. Loser.
January 21, 2026 at 9:20 PM
If you’re a grown ass man in full tactical gear asking a child to show you ID or proof of citizenship you failed at life. Utterly & completely failed. Loser.
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Kamala Harris at her closing campaign rally:
"Donald Trump intends to use the United States Military against American citizens who simply disagree with him."
"Donald Trump intends to use the United States Military against American citizens who simply disagree with him."
August 24, 2025 at 5:26 PM
Kamala Harris at her closing campaign rally:
"Donald Trump intends to use the United States Military against American citizens who simply disagree with him."
"Donald Trump intends to use the United States Military against American citizens who simply disagree with him."
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“The Party told you to reject the evidence of your eyes and ears. It was their final, most essential command.”
—George Orwell, 1984
It is rare for a murder to be captured live on multiple cameras. Yet DHS persists with the obvious lie this was self defense.
There are no more red lines.
—George Orwell, 1984
It is rare for a murder to be captured live on multiple cameras. Yet DHS persists with the obvious lie this was self defense.
There are no more red lines.
January 8, 2026 at 7:29 AM
“The Party told you to reject the evidence of your eyes and ears. It was their final, most essential command.”
—George Orwell, 1984
It is rare for a murder to be captured live on multiple cameras. Yet DHS persists with the obvious lie this was self defense.
There are no more red lines.
—George Orwell, 1984
It is rare for a murder to be captured live on multiple cameras. Yet DHS persists with the obvious lie this was self defense.
There are no more red lines.
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When a cop murdered my big brother at a road block 21 years ago, their post-facto justification was that he tried to run over a cop.
His foot released the brake after the officer shot him in the chest, and the car bumped an officer.
His foot released the brake after the officer shot him in the chest, and the car bumped an officer.
January 7, 2026 at 6:43 PM
When a cop murdered my big brother at a road block 21 years ago, their post-facto justification was that he tried to run over a cop.
His foot released the brake after the officer shot him in the chest, and the car bumped an officer.
His foot released the brake after the officer shot him in the chest, and the car bumped an officer.
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The “prosecute the former regime at every level” candidate has my vote in 2028.
January 7, 2026 at 8:26 PM
The “prosecute the former regime at every level” candidate has my vote in 2028.
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I was one of those immigrants, and we commit fewer crimes than people born here.
“Trump says he wants to “permanently pause migration” from poorer nations and is promising to seek to expel millions of immigrants from the US by revoking their legal status.”
apnews.com/article/trum...
“Trump says he wants to “permanently pause migration” from poorer nations and is promising to seek to expel millions of immigrants from the US by revoking their legal status.”
apnews.com/article/trum...
Trump says he wants to 'permanently pause' migration to the US from poorer countries
President Donald Trump says he wants to “permanently pause migration” from poorer nations and is promising to seek to expel millions of immigrants from the United States by revoking their legal status...
apnews.com
November 28, 2025 at 3:19 PM
I was one of those immigrants, and we commit fewer crimes than people born here.
“Trump says he wants to “permanently pause migration” from poorer nations and is promising to seek to expel millions of immigrants from the US by revoking their legal status.”
apnews.com/article/trum...
“Trump says he wants to “permanently pause migration” from poorer nations and is promising to seek to expel millions of immigrants from the US by revoking their legal status.”
apnews.com/article/trum...
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The effects of genetic variants primarily occur in differentiated cells meaning we need to access these cell types to measure variant effects for most disease genes. We developed saturation genome editing in stem cells (iPSC-SGE) to enable phenotyping in diverse genetic and cell contexts at scale!
Editing stem cell genomes at scale to measure variant effects in diverse cell and genetic contexts
Multiplexed assays of variant effect (MAVEs) systematically measure variant function but have been limited to cancer cell lines rather than disease-relevant cell types. We developed saturation genome ...
www.medrxiv.org
November 22, 2025 at 1:49 AM
The effects of genetic variants primarily occur in differentiated cells meaning we need to access these cell types to measure variant effects for most disease genes. We developed saturation genome editing in stem cells (iPSC-SGE) to enable phenotyping in diverse genetic and cell contexts at scale!
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parents, be sure to check your kids’ candy this halloween. I just found a novel phage defense system inside this snickers
October 4, 2023 at 7:32 PM
parents, be sure to check your kids’ candy this halloween. I just found a novel phage defense system inside this snickers
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I wish people defended smeared victims of sexual violence the way they defend problematic male candidates for office
October 24, 2025 at 2:12 AM
I wish people defended smeared victims of sexual violence the way they defend problematic male candidates for office
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The Portland protest frog has done more to protect American democracy and fight fascism than all but the tiniest handful of elected officials
October 9, 2025 at 6:06 AM
The Portland protest frog has done more to protect American democracy and fight fascism than all but the tiniest handful of elected officials
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Today my @nytimes.com colleagues and I are launching a new series called Lost Science. We interview US scientists who can no longer discover something new about our world, thanks to this year‘s cuts. Here is my first interview with a scientist who studied bees and fires. Gift link: nyti.ms/3IWXbiE
nyti.ms
October 8, 2025 at 11:29 PM
Today my @nytimes.com colleagues and I are launching a new series called Lost Science. We interview US scientists who can no longer discover something new about our world, thanks to this year‘s cuts. Here is my first interview with a scientist who studied bees and fires. Gift link: nyti.ms/3IWXbiE
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Remember, whenever you hear that “speed wasn’t a factor” in a deadly crash, what they mean is that the car involved wasn’t technically speeding. At least “not by much.” It presumes that the speed limit wasn’t too high to begin with.
When it comes to death from collisions, SPEED IS ALWAYS a factor.
When it comes to death from collisions, SPEED IS ALWAYS a factor.
August 21, 2025 at 6:26 PM
Remember, whenever you hear that “speed wasn’t a factor” in a deadly crash, what they mean is that the car involved wasn’t technically speeding. At least “not by much.” It presumes that the speed limit wasn’t too high to begin with.
When it comes to death from collisions, SPEED IS ALWAYS a factor.
When it comes to death from collisions, SPEED IS ALWAYS a factor.
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1. From the FDA to the NSF’s new priorities to Chan-Zuckerberg’s recent pivot, there’s a massive push — particularly on they political right — to hand off as much of the scientific process as possible to AI.
It’s not about competing with China in AI. Not while gutting the US research ecosystem.
It’s not about competing with China in AI. Not while gutting the US research ecosystem.
July 21, 2025 at 2:19 PM
1. From the FDA to the NSF’s new priorities to Chan-Zuckerberg’s recent pivot, there’s a massive push — particularly on they political right — to hand off as much of the scientific process as possible to AI.
It’s not about competing with China in AI. Not while gutting the US research ecosystem.
It’s not about competing with China in AI. Not while gutting the US research ecosystem.
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Congrats to Stephen Colbert for never bending the knee.
July 17, 2025 at 11:59 PM
Congrats to Stephen Colbert for never bending the knee.
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Tedious to point this out, but:
- When a tongue-tied Biden said "President of Mexico" instead of "Prez of Egypt," it was a several day story.
-Hours after Trump says whoever appointed J Powell made a big mistake (it was him), the episode appears not to merit a story on any national-media sites.
- When a tongue-tied Biden said "President of Mexico" instead of "Prez of Egypt," it was a several day story.
-Hours after Trump says whoever appointed J Powell made a big mistake (it was him), the episode appears not to merit a story on any national-media sites.
July 17, 2025 at 4:33 AM
Tedious to point this out, but:
- When a tongue-tied Biden said "President of Mexico" instead of "Prez of Egypt," it was a several day story.
-Hours after Trump says whoever appointed J Powell made a big mistake (it was him), the episode appears not to merit a story on any national-media sites.
- When a tongue-tied Biden said "President of Mexico" instead of "Prez of Egypt," it was a several day story.
-Hours after Trump says whoever appointed J Powell made a big mistake (it was him), the episode appears not to merit a story on any national-media sites.
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🚨 Most variant screens measure growth or abundance. What do they miss? That variants impact a spectrum of protein and cellular phenotypes. Variant in situ sequencing (VIS-seq) finds what’s missing: image cells 🔬 first, decode later, revealing multi-scale phenotypes for thousands of variants.👇
1/9
1/9
July 7, 2025 at 2:44 AM
🚨 Most variant screens measure growth or abundance. What do they miss? That variants impact a spectrum of protein and cellular phenotypes. Variant in situ sequencing (VIS-seq) finds what’s missing: image cells 🔬 first, decode later, revealing multi-scale phenotypes for thousands of variants.👇
1/9
1/9
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Image-based, pooled phenotyping reveals multidimensional, disease-specific variant effects https://www.biorxiv.org/content/10.1101/2025.07.03.663081v1
July 6, 2025 at 7:33 AM
Image-based, pooled phenotyping reveals multidimensional, disease-specific variant effects https://www.biorxiv.org/content/10.1101/2025.07.03.663081v1
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