Borja Mateos
borjaml.bsky.social
Borja Mateos
@borjaml.bsky.social
Assistant Professor at @ub.edu | I like to play with nuclear spins in the triple point (chemistry, biology and physics).
Happy to contribute to this work!
Proud to share our manuscript:

"How small molecules stabilize oligomers of a phase-separating disordered protein"

www.biorxiv.org/content/10.1...

by Jiaqi Zhu and Tommy Sisk, in collaboration with @borjaml.bsky.social , Stase Bielskute-Garcia & @xsalvatella1.bsky.social
November 24, 2025 at 6:48 PM
Reposted by Borja Mateos
Per Joan Massagué, els bons mentors han de reunir diverses qualitats, que es poden resumir en l’acrònim ICECRAM

#InauguracióUPF
September 30, 2025 at 10:33 AM
✨ Couldn’t agree more with Jane Clark’s words on life and science culture! And now… "back to kinetics and mechanisms again!"

Tales of teaching and teamwork | Nature Reviews Chemistry share.google/gtk7OPl6Rmbs...
Tales of teaching and teamwork - Nature Reviews Chemistry
Ahead of her 75th birthday, Jane Clarke discussed her life in science, including her career change from school science teacher to protein folding researcher.
share.google
September 11, 2025 at 8:09 PM
Reposted by Borja Mateos
I’m carrying out a short survey of NMR TITAN users - if you’ve made use of this tool in your research, or have suggestions for its future development, I’d be grateful for your input: forms.gle/MMXYwSozszhi... #nmrchat
NMR TITAN user survey
This survey aims to assess the impact of NMR TITAN on biomolecular research and identify priorities for future development. The form should take approximately 5 minutes to complete. Your responses may...
forms.gle
August 28, 2025 at 2:13 PM
Reposted by Borja Mateos
Happy to share that Javier has been awarded the 2025 RSEQ “Young Researchers” Prize (Postdoctoral category).
We are grateful to the Governing Board for this recognition, which supports our work in organic synthesis and catalysis at @univie.ac.at

rseq.org/concesion-de...
Concesión de los Premios RSEQ 2025 – RSEQ
Concedidos los Premios de la Real Sociedad Española de Química en su edición 2025.
rseq.org
May 1, 2025 at 12:08 PM
Reposted by Borja Mateos
So looking forward to this !
Join us in our plenary #seminar this week, with Prof. Ben Schuler, from the University of Zurich.

Hosted by Dr. @xsalvatella1.bsky.social 

Save your spot now ➡️ https://shorturl.at/e0PCX

🧪
April 7, 2025 at 7:32 AM
Reposted by Borja Mateos
🚨 PhD Opportunity Alert! Repost appreciated!🔁

A fully funded PhD position is available in the Mateos Group at the University of Vienna!

🔹 Up to 4y of funding
🔹 Application deadline: April 21, 2025
👉 More info: doschem.univie.ac.at/application/...

#PhDPosition #Chemistry #Catalysis (1/4)
Open Positions 2025
Open Positions 2025
doschem.univie.ac.at
March 3, 2025 at 1:46 PM
Reposted by Borja Mateos
The Specialised Group of NMR of the Spanish Royal Society of Chemistry (GERMN-RSEQ) is pleased to announce the XVI International Manuel Rico NMR School.
#NMRchat
🗓️1st to 6th June 2025
⛰️Jaca (Spain)
germn.rseq.org/actividades1...
International Manuel Rico NMR School – GERMN
Throughout its editions, this well­established course organized by the specialized Nuclear Magnetic Resonance (NMR) group of the RSEQ (GERMN) has become an excellent platform for improving the underst...
germn.rseq.org
February 23, 2025 at 6:14 PM
Reposted by Borja Mateos
Rocket science alert 🚀!
Check out our latest preprint describing the new sample shuttle developed by @brukercorporation.bsky.social with our friends at @cerm-cirmmp.bsky.social and us. With support from @ec.europa.eu and @agencerecherche.bsky.social #NMRChat #chemsky
A fast sample shuttle to couple high and low magnetic fields. Applications to high-resolution relaxometry
Abstract. Combining high-field high-resolution NMR with an evolution of spin systems at low magnetic field offers many opportunities for the investigation of molecular motions, hyperpolarization and t...
mr.copernicus.org
January 24, 2025 at 2:42 PM
Reposted by Borja Mateos
How do proteins mis-fold?

Paper led by Jacob Aunstrup from Alex Büll’s lab with MD simulations by Abigail Barclay, and key contributions from several others. We combined measurements of Φ-values with MD simulations to study the transition state for amyloid fibril growth

doi.org/10.1038/s415...
January 16, 2025 at 3:08 PM
Reposted by Borja Mateos
📢 New preprint! 📄

Deciphering the molecular forces behind the exceptional binding affinity of the streptavidin-biotin complex via NMR and QM.

🔍 Check it out: www.biorxiv.org/content/10.1...

#StructuralBiology #NMR #ComputationalChemistry #DrugDiscovery
From Weak Interactions to Strong Affinity: Deciphering the Streptavidin-Biotin Interaction through NMR and Computational Analysis
Understanding weak interactions in protein-ligand complexes is essential for advancing drug design. Here, we combine experimental and quantum mechanical approaches to study the streptavidin-biotin com...
www.biorxiv.org
December 22, 2024 at 7:20 PM
Reposted by Borja Mateos
Tips on How to Write ‘Good’
#Matter

PDF download
www.cell.com/action/showP...
December 21, 2024 at 5:38 PM
Reposted by Borja Mateos
This review focuses on the importance of disordered water molecules in protein structures and discusses currently established methods of measuring the hydration states of proteins, their applications, and limitations. ow.ly/wknc50UtrIN
Hidden water’s influence on rhodopsin activation
Structural biology relies on several powerful techniques, but these tend to be limited in their ability to characterize protein fluctuations and mobility. Overreliance on structural approaches can lead to omission of critical information regarding biological function. Currently there is a need for complementary biophysical methods to visualize these mobile aspects of protein function. Here, we review hydrostatic and osmotic pressure-based techniques to address this shortcoming for the paradigm of rhodopsin.
ow.ly
December 19, 2024 at 12:53 PM
Reposted by Borja Mateos
Universidades: Madrid y Catalunya
www.lavanguardia.com/opinion/2024...
Mas-Colell sobre el “trilema” de la universidad: demanda futura, restringir expansión privada, costes crecientes.
Su solución: Permitir a la universidad pública crear entes de derecho privado bajo su control.
Muy interesante.
Universidades: Madrid y Catalunya, por Andreu Mas-Colell
La Comunidad de Madrid, poco amiga de las universidades públicas, está desplegando una política favorable a la creación y expansión de universidades privadas. En
www.lavanguardia.com
December 17, 2024 at 12:30 PM
Reposted by Borja Mateos
1. I feel like this is such obvious advice that it gets taken for granted & consequently no one says this to young scientists but READ PAPERS, read all the papers. As you move up in your career you will have less & less time to do this. Read everything that appeals to you not just in your field
December 13, 2024 at 4:21 PM
Full room today to see Albert' (from @benlehner.bsky.social lab at @crg.eu ) work! Really insightful datasets!
December 11, 2024 at 6:38 PM
Reposted by Borja Mateos
Our work on how CPEB4 mis-splicing leads to its aggregation in autism spectrum disorder is now published in Nature.

rdcu.be/d2qjW

I would like to thank the collaborators who joined the team during the revision process as well as the funders who supported us.
December 4, 2024 at 10:13 PM
Reposted by Borja Mateos
🫧🔍Key breakthrough in #autism: pivotal role of #CPEB4 condensates revealed.

💊The study opens new avenues for the development of targeted treatments for autism.

📰 Nature @natureportfolio.bsky.social

✍️ Carla Garcia-Cabau, Anna Bartomeu et al.

➡️ bit.ly/3BfEGlR

📌 DOI: 10.1038/s41586-024-08289-w
December 4, 2024 at 4:00 PM
Reposted by Borja Mateos
It's a little bit late, but I'm really excited for my first paper! For reaction monitoring by NMR, signal-averaging can be applied *after acquisition*, and results in better S/N *and* data density without the typical trade-off. pubs.acs.org/doi/10.1021/... #NMRchat #NMR @lloydjonesgroup.bsky.social
Simple Parameters and Data Processing for Better Signal-to-Noise and Temporal Resolution in In Situ 1D NMR Reaction Monitoring
In situ 1D NMR spectroscopic reaction monitoring allows detailed investigation of chemical kinetics and mechanism. Concentration versus time data are derived from a time series of NMR spectra. Each sp...
pubs.acs.org
December 1, 2024 at 5:35 PM
Reposted by Borja Mateos
Closing ceremony of the #CrazyAboutBiomedicine Program: 25 secondary school students have completed a year of scientific immersion in #IRBBarcelona’s labs, working on innovative experiments under the mentorship of researchers from our centre.

➡️ bit.ly/415wmiY

🧪
November 27, 2024 at 2:44 PM
Reposted by Borja Mateos
This is a great opportunity to join our group as PhD student to investigate the role(s) of intrinsically disordered proteins in biomedicine !
🚀 Ready to take your passion for science to the next level? Pursue a #PhD in a world-class research environment with us!

✨Kickstart your dream career. Your journey in #biomedicine begins here!

Check out our fellowships programs below!

🧪
November 26, 2024 at 12:49 PM