Lightnews — Scholar-powered news

Reposted by Alfonso Valencia

cniostopcancer.bsky.social @cniostopcancer.bsky.social · 2d

Es el 2º en el mundo con la certificación de la @iscb.bsky.social. Codirigido por Fátima Al-Sharour @bioinformatics.cnio.es y @alfonsovalencia.bsky.social, enseña a aplicar #ia y #aprendizajeautomático a problemas concretos en investigación biomédica, diagnóstico clínico o terapias personalizadas.

1 1 3

Reposted by Alfonso Valencia

EvoMG Program @evomg-bcn.bsky.social · 3d

After the coffee break, we had a round table about dealing with evolution of drug resistance & synergies among EvoMG fields. We had a panel representing the different related "areas": Isabel Veiga (Plasmodium), David Posada (Cancer), Jero Rodriguez (Bacteria), Ana Abecasis (Virus).

1 2 3

Reposted by Alfonso Valencia

EvoMG Program @evomg-bcn.bsky.social · 3d

Next was Alfonso Valencia ( @alfonsovalencia.bsky.social), from the Barcelona Supercomputing Centre (BSC), who introduced the computing infrastructure at BSC and his work on co-morbidities.

1 1 2

Reposted by Alfonso Valencia

STAT @statnews.com · 3d

Almost the entire staff of Morbidity and Mortality Weekly Report, known as the “voice of the CDC,” has been laid off, former publication editor-in-chief Charlotte Kent told STAT Saturday.
www.statnews.com/2025/10/11/c...

Deep cuts made to CDC's flagship MMWR publication, a cornerstone of public health

CDC staff behind the agency’s flagship publication have been fired amid drastic cuts to the HHS promised by the White House due to the government shutdown, according to five people familiar with the s...

www.statnews.com

3 51 66

Reposted by Alfonso Valencia

BSC-CNS @bsc-cns.bsky.social · 9d

🌐Agile, safe, and sustainable access to European health data to accelerate biomedical research.

A study led by BSC reveals that the lack of alignment in criteria and organizational barriers pose a challenge to the development and implementation of the European Health Data Space (EHDS)

1 1 2

Reposted by Alfonso Valencia

#BruceSterling @bruces.bsky.social · 11d

*Being a science fiction writer, I tend to look for the "oxymorons" instead of the "empty holes," but I'm extremely keen on approaches like this

*I'm not sure it matters much if AIs explore the "previously unthinkable" in the "holes," but at least that's not "baked-in," so it's easy to notice

Larry Hunter @proflhunter.bsky.social · 11d

Wishful metaphor? These days I look for the empty holes in the rocks. Which are important because they tell us where to do the next science. Like www.sciencedirect.com/science/arti...
or www.nature.com/articles/s41...

Creating an ignorance-base: Exploring known unknowns in the scientific literature

Scientific discovery progresses by exploring new and uncharted territory. More specifically, it advances by a process of transforming unknown unknowns…

www.sciencedirect.com

2 14

Reposted by Alfonso Valencia

Science Media Centre España @sciencemediacentre.es · 12d

✴️Buscan aumentar la bioseguridad ante el riesgo de fabricar proteínas peligrosas con IA

🗨️ @alfonsovalencia.bsky.social: "Lo que viene a la mente es una variante más infecciosa del coronavirus. Hace un año David Baker y George Church advirtieron de los peligros"
sciencemediacentre.es/buscan-aumen...

1 4

Reposted by Alfonso Valencia

BSC-CNS @bsc-cns.bsky.social · 15d

🚀Premios #BSCConnects – Tech for Impact Awards en la Barcelona Deep Tech Summit!

⏰ Inscripciones abiertas hasta el 23 de octubre
🌐Ya podéis consultar los retos: bsc.es/bscconnectsa...

#IA #supercomputación #InnovationBSC

2 1

Reposted by Alfonso Valencia

Ricard Castellet @ricardcastellet.bsky.social · Nov 17

Article de @blancagispert.bsky.social sobre el Barcelona Supercomputing Center, un dels grans èxits de l'ecosistema d'innovació que està en fase de creixement i reforçant la tan necessària transferència de coneixement. Felicitats @marionasanz.bsky.social & team

3 8

Alfonso Valencia @alfonsovalencia.bsky.social · 16d

. @lavanguardia.com , por favor!

1 5

Reposted by Alfonso Valencia

REPO4EU @repo4eu.bsky.social · 23d

Meet the #RExPO25 Honorary Lecturer 💊 Alfonso Valencia (@bsc-cns.bsky.social)

We're honoured to welcome @alfonsovalencia.bsky.social to this year's conference! In his lecture, he'll reflect on advancing #Biomedicine through computing, networks & AI.

Check the full agenda ➡️ repo4.eu/rexpo25/agen...

RExPO25 Honorary Lecturer: Alfonso Valencia, Barcelona Supercomputing Center (BSC). Title: Advancing biomedicine through computing, networks and AI - opportunities and challenges.

3 4

Reposted by Alfonso Valencia

Nature Methods @natmethods.nature.com · 26d

GPU-accelerated MMseqs2 offers tremendous speedup for homology retrieval, protein structure prediction with ColabFold, and protein structure search with Foldseek. @martinsteinegger.bsky.social @milot.bsky.social @machine.learning.bio

www.nature.com/articles/s41...

GPU-accelerated homology search with MMseqs2 - Nature Methods

Graphics processing unit-accelerated MMseqs2 offers tremendous speedups for homology retrieval from metagenomic databases, query-centered multiple sequence alignment generation for structure predictio...

www.nature.com

21 81

Reposted by Alfonso Valencia

CATH-Gene3D @cathgene3d.bsky.social · 29d

And now @gonzaparra.bsky.social on his first talk on protein frustration as a PI! Well done!

1 2 6

Reposted by Alfonso Valencia

Luís M. Rocha @lmrocha.bsky.social · Sep 3

Great #networkmedicine work by @alfonsovalencia.bsky.social's team on deriving comorbidity networks from RNA-seq data to study complex disease relationships. Thy show that molecular mechanisms are behind many of the known comorbidities (often via immune response).
doi.org/10.1073/pnas...

Patient stratification reveals the molecular basis of disease co-occurrences | PNAS

Epidemiological evidence shows that some diseases tend to co-occur; more exactly, certain groups of patients with a given disease are at a higher r...

doi.org

1 2 4

Reposted by Alfonso Valencia

BSC-CNS @bsc-cns.bsky.social · Sep 9

💻🧬'Los vínculos secretos que existen entre enfermedades.
El estudio del BSC representa el mayor esfuerzo hasta la fecha para explicar científicamente las asociaciones clínicas entre enfermedades'

🗞En @innovaspain.bsky.social
➡ www.bsc.es/4kD

@alfonsovalencia.bsky.social @beatrizurda.bsky.social

3 3

Reposted by Alfonso Valencia

Beatriz Urda @beatrizurda.bsky.social · Sep 8

Excited to see our PNAS paper highlighted on Kudos, with an accessible take on the findings.

Disease links are not random—they can be predicted from the expression of our genes.
www.growkudos.com/publications...

@pnas.org @alfonsovalencia.bsky.social
📄 doi.org/10.1073/pnas...

Molecular map reveals hidden disease connections

Diseases rarely come alone. Many people experience a chain of diagnoses across their lives—for example, smoking-related lung cancer, asthma followed by Parkinson’s disease, or depression alongside lup...

www.growkudos.com

1 4 8

Reposted by Alfonso Valencia

Beatriz Urda @beatrizurda.bsky.social · Sep 2

7/ Huge thanks to @alfonsovalencia.bsky.social for his continued support and excitement in this wild, fascinating project, and to all co-authors (Jon,Alba) & funding agencies. To the @bsc-cns.bsky.social for indispensable comput. resources, and to all patients & teams who made omic data available.

1 1 3

Alfonso Valencia @alfonsovalencia.bsky.social · Sep 2

She explains part of the fight over 2 years with an absurd referee (can happen) and an incompetent profesional editor unable to understand even basic statistics - or worse unable to take a decision by him/her self.

But never mind: Beatriz won and the paper is now published in a better journal.

Beatriz Urda @beatrizurda.bsky.social · Sep 2

1/ Everything that could go wrong in paper publishing… did.
A story of patience, absurdity, and persistence 🌀 <1min

From Alfonso Valencia’s lab and a very stubborn PhD student (me).

1 9

Reposted by Alfonso Valencia

Beatriz Urda @beatrizurda.bsky.social · Sep 2

1/ Everything that could go wrong in paper publishing… did.
A story of patience, absurdity, and persistence 🌀 <1min

From Alfonso Valencia’s lab and a very stubborn PhD student (me).

1 14 31

Alfonso Valencia @alfonsovalencia.bsky.social · Sep 2

Very happy to get it out.

For scientific & personal reasons this one is special.
Beatriz has done more work and endured the most difficult - and absurd - publications battles I can remember.
Thanks to PNAS for being "normal" and congratulations to Beatriz.

(Beatriz: next one will be easier!)

Beatriz Urda @beatrizurda.bsky.social · Sep 2

🚨 New in PNAS!
🧬 64% of disease co-occurrences can be explained by transcriptomic similarities.

Comorbidities aren’t random—they have a molecular basis.

Here’s how we found it 👇 (1/n)

🔗 doi.org/10.1073/pnas.2421060122

@alfonsovalencia.bsky.social

1 8

Reposted by Alfonso Valencia

Beatriz Urda @beatrizurda.bsky.social · Sep 2

🚨 New in PNAS!
🧬 64% of disease co-occurrences can be explained by transcriptomic similarities.

Comorbidities aren’t random—they have a molecular basis.

Here’s how we found it 👇 (1/n)

🔗 doi.org/10.1073/pnas.2421060122

@alfonsovalencia.bsky.social

1 14 27

Alfonso Valencia @alfonsovalencia.bsky.social · Aug 28

elpais.com/espana/2025-...

No estaría mal llegar también en ciencia, no?
(sector empresarial,,, financiando el 0,72% del gasto en I+D sobre PIB y ejecutando el 0,84%. … sector público ha financiado el 0,63% del gasto en I+D sobre PIB y ha ejecutado el 0,65%) informe del ministerio - julio 2025

La OTAN calcula que España ha llegado al 2% de su gasto del PIB en defensa

Un informe de la Alianza muestra que el Gobierno cumple por primera vez con el objetivo acordado en 2014 para esta década

elpais.com

2 4

Alfonso Valencia @alfonsovalencia.bsky.social · Aug 27

Quoting Miguel Ponce de Leon main author of the paper: “our work provides a novel approach to study the effect of interregional mobility on epidemic spread & to uncover spatio-temporal patterns of mobility-driven transmission, with insights to inform the timing and regional targeting of NPI”

CREXDATA - Critical Action Planning Over Extreme-Scale Data @crexdata-eu.bsky.social · Aug 27

📢 New Publication Alert!

The study uses an advanced method called Transfer Entropy on massive phone mobility datasets to map the influence of travel on COVID-19 spread across Spain

Find the full open-access paper here: crexdata.eu/publication/...

@alfonsovalencia.bsky.social @bsc-cns.bsky.social

3

Reposted by Alfonso Valencia

CREXDATA - Critical Action Planning Over Extreme-Scale Data @crexdata-eu.bsky.social · Aug 27

📢 New Publication Alert!

The study uses an advanced method called Transfer Entropy on massive phone mobility datasets to map the influence of travel on COVID-19 spread across Spain

Find the full open-access paper here: crexdata.eu/publication/...

@alfonsovalencia.bsky.social @bsc-cns.bsky.social

1 2

Alfonso Valencia @alfonsovalencia.bsky.social · Aug 23

I wonder why this book - and not only this one- is more expensive in Spanish than in Italian in the Apple Store?

1