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Chris Waudby @chriswaudby.bsky.social · 22d

So excited that our lab's first home-grown paper is now available on ChemRxiv!

Kinetic NMR screening: rapidly quantifying fast ligand dissociation in fragment mixtures using ¹⁹F relaxation dispersion | doi.org/10.26434/che... 🧲🧪

Kinetic NMR screening: rapidly quantifying fast ligand dissociation in fragment mixtures using ¹⁹F relaxation dispersion

Ligand-observed NMR is a key tool for detecting weak protein-ligand interactions, but translating binding signals into meaningful affinity measurements remains difficult, limiting the ability to rank ...

doi.org

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Chris Waudby @chriswaudby.bsky.social · 24d

It was recorded so I think so - will let you know!

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Chris Waudby @chriswaudby.bsky.social · 27d

Celebrating the submission of my lab’s first fully home-grown paper 🥂 Appearing on @chemrxiv.org soon!

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Chris Waudby @chriswaudby.bsky.social · 28d

Looking forward to giving a webinar tomorrow with @nickynak3.bsky.social about our efforts to establish a 19F NMR fragment screening platform at UCL. Register below and join us to find out more!

Friday 19th September, 2pm (UK)
www.eventbrite.co.uk/e/webinar-fr... #NMRchat #NMR @ucltro.bsky.social

Webinar: Fragment Screening using 19F NMR at the UCL School of Pharmacy

Join Dr Nikita Harvey and Dr Christopher Waudby to delve into the subject and interact with research fellows.

www.eventbrite.co.uk

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Chris Waudby @chriswaudby.bsky.social · Sep 13

Many congratulations Mirek and Tomáš - it was a pleasure to be a part of the day and I’ve come away knowing a lot more about Wnt!

Bryjalab @bryjalab.bsky.social · Sep 13

Big day for Bryjalab yesterday! Mirek Micka & Tomáš Gybeľ nailed their defences — welcome to the PhD club! 🎓🔥 Thanks to everyone who supported them along the way and came to celebrate! 🎉🤗

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Reposted by Chris Waudby

Bryjalab @bryjalab.bsky.social · Sep 11

The science marathon continues. 🏃
Straight off #EBBM2025, BryjaLab is co-organizing with Tripsianes’ lab at @ceitec.eu the Milestone Minisymposium on Cell Signalling, kicking off today with great talks by @chriswaudby.bsky.social & @michaelranes.bsky.social. More talks & two PhD defenses tomorrow 🎓

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Chris Waudby @chriswaudby.bsky.social · Aug 28

I’m carrying out a short survey of NMR TITAN users - if you’ve made use of this tool in your research, or have suggestions for its future development, I’d be grateful for your input: forms.gle/MMXYwSozszhi... #nmrchat

NMR TITAN user survey

This survey aims to assess the impact of NMR TITAN on biomolecular research and identify priorities for future development. The form should take approximately 5 minutes to complete. Your responses may...

forms.gle

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Chris Waudby @chriswaudby.bsky.social · Aug 14

Thrilled to be at the opening of the UK’s first 1.2 GHz NMR spectrometer at Warwick University, soon to be followed by a second in Birmingham! A huge investment in the NMR community from @ukri.org - I can’t wait to collect my first spectra and see what new discoveries will emerge! #nmrchat

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Reposted by Chris Waudby

UCL Translational Research Office @ucltro.bsky.social · Aug 14

Fragment Screening using 19F NMR at the UCL School of Pharmacy: Principles, Practice, and Applications
Date: Friday 19 Sep, 2-3pm
Speaker: Dr Nikita Harvey, Specialist Services Manager (NMR); Dr Christopher Waudby, Lecturer in Biomolecular NMR at the School of Pharmacy
✅Register now: bit.ly/4lpBftT

Webinar: Fragment Screening using 19F NMR at the UCL School of Pharmacy

Join Dr Nikita Harvey and Dr Christopher Waudby to delve into the subject and interact with research fellows.

bit.ly

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Chris Waudby @chriswaudby.bsky.social · Aug 8

26 July ❤️

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Reposted by Chris Waudby

Nikita Harvey @nickynak3.bsky.social · Jul 10

Today we're having a cooling/heating rack installed into our NMR liquid handling robot! This should help keep protein and DNA samples stable during prep for our 19F fragment screening service #NMRchat

www.ucl.ac.uk/pharmacy/abo...

Two Bruker engineers installing the cooling rack on the SamplePro Tube liquid handler

Bruker SamplePro Tube liquid handler with the new cooling rack installed. The cover is open and the robot is lit by a blue LED strip.

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Reposted by Chris Waudby

xavier salvatella @xsalvatella1.bsky.social · Nov 26

This is a great opportunity to join our group as PhD student to investigate the role(s) of intrinsically disordered proteins in biomedicine !

IRB Barcelona @irbbarcelona.org · Nov 26

🚀 Ready to take your passion for science to the next level? Pursue a #PhD in a world-class research environment with us!

✨Kickstart your dream career. Your journey in #biomedicine begins here!

Check out our fellowships programs below!

🧪

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Chris Waudby @chriswaudby.bsky.social · Nov 25

I'll be performing in the UCL Chamber Music Club's next concert, 5.30 pm on Wed 4th Dec. Come and join us for a programme of piano music for 2 and 4 hands spanning three continents. Admission is free and open to all.

www.ucl.ac.uk/chamber-musi...

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Chris Waudby @chriswaudby.bsky.social · Nov 25

Pushed a new update to NMRTools.jl this afternoon, with some bug fixes and improved compatibility with Windows files.

Find out more at: waudbylab.org/NMRTools.jl/...

🧲 #julia

Home · NMRTools.jl

Documentation for NMRTools.jl.

waudbylab.org

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Reposted by Chris Waudby

Adam Clancy @clancylab.bsky.social · Nov 25

Bluesky is really taking off with STEM academics across UCL, so I thought it was time we had our own Starter Pack

#academicsky #chemsky #stem #sciencesky #research #chemeng

go.bsky.app/9ZnMnCd

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Chris Waudby @chriswaudby.bsky.social · Nov 7

Looking forward to a seminar this Thursday (9 Nov) from Xavier Salvatella, IRB Barcelona:

“Kinetic stabilization of translation-repression condensates by a neuron-specific microexon”.

Gavin de Beer LT, Anatomy Building, UCL, 1-2pm.

#NMRchat 🧪

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Chris Waudby @chriswaudby.bsky.social · Oct 20

Looking forward to presenting this beautiful paper from Uli Hommel and colleagues at Novartis as a case study in biomolecular NMR to our MSc Drug Discovery students this afternoon. 🧪 #NMR

Discovery of a selective and biologically active low-molecular weight antagonist of human interleuki...

Interleukin-1β is a pro-inflammatory cytokine of medical importance. Here the authors describe the discovery of a low-molecular weight compound that antagonizes hIL-1β function in cells, demonstrati...

www.nature.com

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Reposted by Chris Waudby

Jake Yeston @jakeyeston.bsky.social · Sep 21

In Science this week, Rafal Klajn and collaborators use visible light and spatial constraints to build up the disfavored azobenzene isomer

Chemsky 🧪

www.science.org/doi/full/10....

Science | AAAS

www.science.org

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Chris Waudby @chriswaudby.bsky.social · Sep 21

Disgusted by the UK government’s abandonment of its climate policy? Turn your anger into something more positive:

1. Sign your lab up to LEAF www.ucl.ac.uk/sustainable/...
2. Pledge to take trains over planes
3. Embed sustainability in your teaching
4. Vote!

#AcademicSky 🧪

LEAF - Laboratory Efficiency Assessment Framework

LEAF is a standard set by UCL to improve the sustainability and efficiency of laboratories. Join the 85 global institutions already taking part and help address the climate and ecological emergencies

www.ucl.ac.uk

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Chris Waudby @chriswaudby.bsky.social · Sep 20

Hello 👋 I’m Chris, an NMR spectroscopist and protein chemist at UCL interested in protein (mis)folding and glycan quality control, as well as NMR method and software development (big fan of #julialang). May also post cute photos of our dog. More at waudbylab.org. chemsky #AcademicSky #LGBTSTEM 🧪

The Waudby Group

waudbylab.org

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Chris Waudby @chriswaudby.bsky.social · Sep 20

Hi @danirabaiotti.bsky.social please add me as a contributor (lecturer at UCL school of pharmacy)

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