Amro Hussien
@amrohussien.bsky.social
HFSP/EMBO Fellow @MaxPlanck.de (Wickström Lab) | Prev. @ETHZ.ch, @UCL.ac.uk |
First-principles in: #Mechanobiology • #EpigeneticMemories • #Inflammation • #Tendon
First-principles in: #Mechanobiology • #EpigeneticMemories • #Inflammation • #Tendon
Reposted by Amro Hussien
Congratulations to the new cohort of 28 EMBO Young Investigators! They are joining an international network of more than 800 life scientists – Welcome!
Read the press release here:
https://www.embo.org/press-releases/twenty-eight-group-leaders-become-embo-young-investigators/
Read the press release here:
https://www.embo.org/press-releases/twenty-eight-group-leaders-become-embo-young-investigators/
December 2, 2025 at 1:06 PM
Congratulations to the new cohort of 28 EMBO Young Investigators! They are joining an international network of more than 800 life scientists – Welcome!
Read the press release here:
https://www.embo.org/press-releases/twenty-eight-group-leaders-become-embo-young-investigators/
Read the press release here:
https://www.embo.org/press-releases/twenty-eight-group-leaders-become-embo-young-investigators/
Reposted by Amro Hussien
Happy birthday to #LaskerLaureate Richard O. Hynes! He was recognized for his discoveries concerning integrins, which are key mediators of cell matrix and cell-cell adhesion in physiology and disease. 🧪
Read: buff.ly/metevu2
Watch: buff.ly/z4WQFA5
Read: buff.ly/metevu2
Watch: buff.ly/z4WQFA5
Integrins—mediators of cell-matrix and cell-cell adhesion - Lasker Foundation
Explore All 2022 Winners & Awards > Richard O. Hynes Massachusetts Institute of Technology Erkki Ruoslahti Sanford Burnham Prebys Timothy A. Springer Boston Children’s Hospital/Harvard Medical School…
buff.ly
November 29, 2025 at 6:02 PM
Happy birthday to #LaskerLaureate Richard O. Hynes! He was recognized for his discoveries concerning integrins, which are key mediators of cell matrix and cell-cell adhesion in physiology and disease. 🧪
Read: buff.ly/metevu2
Watch: buff.ly/z4WQFA5
Read: buff.ly/metevu2
Watch: buff.ly/z4WQFA5
Reposted by Amro Hussien
Nature research paper: Ethylene modulates cell wall mechanics for root responses to compaction
go.nature.com/4rmhdEI
go.nature.com/4rmhdEI
Ethylene modulates cell wall mechanics for root responses to compaction - Nature
Soil compaction traps ethylene around roots, which causes transcriptional upregulation of Auxin Response Factor1, resulting in decreased root cortical cell wall thickness and thereby promoting root radial expansion.
go.nature.com
November 28, 2025 at 1:23 PM
Nature research paper: Ethylene modulates cell wall mechanics for root responses to compaction
go.nature.com/4rmhdEI
go.nature.com/4rmhdEI
Reposted by Amro Hussien
The strategic use of multiple models clarifies a longstanding controversy in pulmonary fibrosis
Dean Sheppard & team establish fibroblast proliferation as an important driver (and potential target) in pulmonary fibrosis: www.jci.org/articles/vie...
Dean Sheppard & team establish fibroblast proliferation as an important driver (and potential target) in pulmonary fibrosis: www.jci.org/articles/vie...
November 25, 2025 at 2:02 PM
The strategic use of multiple models clarifies a longstanding controversy in pulmonary fibrosis
Dean Sheppard & team establish fibroblast proliferation as an important driver (and potential target) in pulmonary fibrosis: www.jci.org/articles/vie...
Dean Sheppard & team establish fibroblast proliferation as an important driver (and potential target) in pulmonary fibrosis: www.jci.org/articles/vie...
Reposted by Amro Hussien
Motivational video for #MigrationMovieMonday. A persistent 4T1 breast cancer cell squeezing itself through a tight constriction despite undergoing repetitive nuclear envelope rupture. Credit: Kristen Nedza @weillinstitute.bsky.social
November 25, 2025 at 1:36 AM
Motivational video for #MigrationMovieMonday. A persistent 4T1 breast cancer cell squeezing itself through a tight constriction despite undergoing repetitive nuclear envelope rupture. Credit: Kristen Nedza @weillinstitute.bsky.social
Reposted by Amro Hussien
Handwritten notes are more useful for studying and committing to memory than typed notes, ultimately contributing to higher achievement for college students.
link.springer.com/article/10.1...
link.springer.com/article/10.1...
November 20, 2025 at 5:11 PM
Handwritten notes are more useful for studying and committing to memory than typed notes, ultimately contributing to higher achievement for college students.
link.springer.com/article/10.1...
link.springer.com/article/10.1...
Reposted by Amro Hussien
Terrific new work on tendon growth by Heather Dingwall @dingwallaby.bsky.social and @jennagalloway.bsky.social in collaboration with my lab. Congrats Heather and all authors! journals.plos.org/plosgenetics...
Dynamic transcriptional and epigenetic changes define postnatal tendon growth
Author summary Tendons provide essential connections within our musculoskeletal system, transmitting the force from muscle to bone to enable movement. Concomitant with skeletal growth, tendon developm...
journals.plos.org
November 19, 2025 at 11:57 AM
Terrific new work on tendon growth by Heather Dingwall @dingwallaby.bsky.social and @jennagalloway.bsky.social in collaboration with my lab. Congrats Heather and all authors! journals.plos.org/plosgenetics...
Reposted by Amro Hussien
It’s not just a figure of speech to say tech titans are indifferent to humanity.
From Peter Thiel to Elon Musk, many are adherents of a worldview that envisions humans being replaced by digital post-humans and sees this as progress.
From Peter Thiel to Elon Musk, many are adherents of a worldview that envisions humans being replaced by digital post-humans and sees this as progress.
Tech Capitalists Don’t Care About Humans. Literally.
It’s not just a figure of speech to say tech titans are indifferent to humanity. From Peter Thiel to Elon Musk, many are adherents of a worldview that envisions humans being replaced by digital post-humans and sees this as progress.
jacobin.com
November 17, 2025 at 8:29 PM
It’s not just a figure of speech to say tech titans are indifferent to humanity.
From Peter Thiel to Elon Musk, many are adherents of a worldview that envisions humans being replaced by digital post-humans and sees this as progress.
From Peter Thiel to Elon Musk, many are adherents of a worldview that envisions humans being replaced by digital post-humans and sees this as progress.
Reposted by Amro Hussien
So awesome to have this great paper from Sam Reffsin and Sara Cherry out! In it, we use retrospective clone tracing to show that there are particular single cell states that are more susceptible to viral infection (both SARS-CoV-2 and flu)!
www.cell.com/cell/fulltex...
www.cell.com/cell/fulltex...
Single-cell susceptibility to viral infection is driven by variable cell states
Not all cells that can be infected by a virus become infected with that virus. Single-cell
clone tracing reveals intrinsic cell states with variable expression patterns that
increase susceptibility to...
www.cell.com
November 14, 2025 at 4:47 PM
So awesome to have this great paper from Sam Reffsin and Sara Cherry out! In it, we use retrospective clone tracing to show that there are particular single cell states that are more susceptible to viral infection (both SARS-CoV-2 and flu)!
www.cell.com/cell/fulltex...
www.cell.com/cell/fulltex...
Reposted by Amro Hussien
“The authoritarianism of digital modernity operates through faceless collectivity. Its commands arrive not as decrees but as design choices. Its tyrannies are those of the nudge, the notification, the algorithm.”
— @pettertornberg.com & @uitermark.bsky.social
— @pettertornberg.com & @uitermark.bsky.social
The Ascendance Of Algorithmic Tyranny | NOEMA
As today’s platforms become all-powerful, the metaphors we use to describe our digitally infused world exemplify a new, stealthier form of domination that is emerging.
www.noemamag.com
November 15, 2025 at 5:30 PM
“The authoritarianism of digital modernity operates through faceless collectivity. Its commands arrive not as decrees but as design choices. Its tyrannies are those of the nudge, the notification, the algorithm.”
— @pettertornberg.com & @uitermark.bsky.social
— @pettertornberg.com & @uitermark.bsky.social
Reposted by Amro Hussien
Memories shift and change over time. Now, researchers say they can be manipulated even further—and that could actually help patients with brain disorders.
Memories Change. But Can We Change Them On Purpose?
Neuroscientists are manipulating memories in mice in an effort to develop treatments for brain disorders.
buff.ly
November 14, 2025 at 6:24 PM
Memories shift and change over time. Now, researchers say they can be manipulated even further—and that could actually help patients with brain disorders.
Reposted by Amro Hussien
With transcriptomic and functional data, @lucamasin.bsky.social et al. @labmoons.bsky.social show that local glycolysis supports injury-induced axonal regeneration. rupress.org/jcb/article/...
📕 In Cellular Neurobiology collection: rupress.org/jcb/collecti...
#SfN25
📕 In Cellular Neurobiology collection: rupress.org/jcb/collecti...
#SfN25
November 14, 2025 at 6:15 PM
With transcriptomic and functional data, @lucamasin.bsky.social et al. @labmoons.bsky.social show that local glycolysis supports injury-induced axonal regeneration. rupress.org/jcb/article/...
📕 In Cellular Neurobiology collection: rupress.org/jcb/collecti...
#SfN25
📕 In Cellular Neurobiology collection: rupress.org/jcb/collecti...
#SfN25
Reposted by Amro Hussien
And here is the story after peer review. This work highlights our current approach, which is to use Piezo channels to uncover new areas of biology that are shaped by mechanical forces: www.science.org/doi/10.1126/...
November 13, 2025 at 10:05 PM
And here is the story after peer review. This work highlights our current approach, which is to use Piezo channels to uncover new areas of biology that are shaped by mechanical forces: www.science.org/doi/10.1126/...
Reposted by Amro Hussien
A couple of years ago, a smattering of A.I. tracks went viral for using tricks like replicating the voices of pop stars, including Jay-Z and Drake. Now we’re in the midst of a full-blown A.I. music moment, @chaykak writes. https://newyorkermag.visitlink.me/m6CdDF
That New Hit Song on Spotify? It Was Made by A.I.
Aspiring musicians are churning out tracks using generative artificial intelligence. Some are topping the charts.
newyorkermag.visitlink.me
November 13, 2025 at 6:00 PM
A couple of years ago, a smattering of A.I. tracks went viral for using tricks like replicating the voices of pop stars, including Jay-Z and Drake. Now we’re in the midst of a full-blown A.I. music moment, @chaykak writes. https://newyorkermag.visitlink.me/m6CdDF
Reposted by Amro Hussien
“Even when I was an assistant professor, I would say things like, ‘I’m a researcher.’ I wouldn’t say I’m a scientist.” Nobel Laureate Ardem Patapoutian made groundbreaking discoveries about the sense of touch. But he didn’t always have a sense of belonging in science.
Even Nobel Prize Winners Deal With Imposter Syndrome
Neuroscientist Ardem Patapoutian immigrated to the US, found belonging in science, and did groundbreaking work on sense of touch.
buff.ly
November 11, 2025 at 7:13 PM
“Even when I was an assistant professor, I would say things like, ‘I’m a researcher.’ I wouldn’t say I’m a scientist.” Nobel Laureate Ardem Patapoutian made groundbreaking discoveries about the sense of touch. But he didn’t always have a sense of belonging in science.
Reposted by Amro Hussien
🚀 Exciting news! ERC Synergy Grant of €8.5 million to Sara Wickström @sarawickstrom.bsky.social, Daniel St Jonston @gurdoninstitute.bsky.social and Ewa Paluch @universitypress.cambridge.org! This highly interdisciplinary project will boost our understanding of tissue biology. #ERCSyG @erc.europa.eu
November 6, 2025 at 11:21 AM
🚀 Exciting news! ERC Synergy Grant of €8.5 million to Sara Wickström @sarawickstrom.bsky.social, Daniel St Jonston @gurdoninstitute.bsky.social and Ewa Paluch @universitypress.cambridge.org! This highly interdisciplinary project will boost our understanding of tissue biology. #ERCSyG @erc.europa.eu
Reposted by Amro Hussien
Research | Amiad Pavlov, Heffler et al. demonstrate that stress transmitted to the cardiomyocyte nucleus by the microtubule cage drives LMNA-associated cardiomyopathy and may represent a promising therapeutic target.
doi.org/10.1038/s441...
rdcu.be/eOeTA
doi.org/10.1038/s441...
rdcu.be/eOeTA
Microtubule forces drive nuclear damage in LMNA cardiomyopathy - Nature Cardiovascular Research
Amiad Pavlov, Heffler, et al. demonstrate that stress transmitted to the cardiomyocyte nucleus by the microtubule cage drives LMNA-associated cardiomyopathy and may represent a promising therapeutic t...
doi.org
November 4, 2025 at 2:56 PM
Research | Amiad Pavlov, Heffler et al. demonstrate that stress transmitted to the cardiomyocyte nucleus by the microtubule cage drives LMNA-associated cardiomyopathy and may represent a promising therapeutic target.
doi.org/10.1038/s441...
rdcu.be/eOeTA
doi.org/10.1038/s441...
rdcu.be/eOeTA
Reposted by Amro Hussien
Broad has launched the Biology of Adversity Project, led by
@jbuenrostro.bsky.social a 2023 @macfound.org fellow, to uncover how adverse life experiences can inflict molecular “scars” in the genome and body and increase risk of heart disease and other disorders. Learn more: broad.io/BAP
@jbuenrostro.bsky.social a 2023 @macfound.org fellow, to uncover how adverse life experiences can inflict molecular “scars” in the genome and body and increase risk of heart disease and other disorders. Learn more: broad.io/BAP
November 4, 2025 at 4:26 PM
Broad has launched the Biology of Adversity Project, led by
@jbuenrostro.bsky.social a 2023 @macfound.org fellow, to uncover how adverse life experiences can inflict molecular “scars” in the genome and body and increase risk of heart disease and other disorders. Learn more: broad.io/BAP
@jbuenrostro.bsky.social a 2023 @macfound.org fellow, to uncover how adverse life experiences can inflict molecular “scars” in the genome and body and increase risk of heart disease and other disorders. Learn more: broad.io/BAP
Reposted by Amro Hussien
NEW from me:
Political hostility, high visa fees and (in the case of the UK) stagnant incomes are making the UK and US less attractive destinations for top international talent.
That steep decline in the appeal of moving to the US after 2016 is 👀
Political hostility, high visa fees and (in the case of the UK) stagnant incomes are making the UK and US less attractive destinations for top international talent.
That steep decline in the appeal of moving to the US after 2016 is 👀
October 31, 2025 at 2:32 PM
NEW from me:
Political hostility, high visa fees and (in the case of the UK) stagnant incomes are making the UK and US less attractive destinations for top international talent.
That steep decline in the appeal of moving to the US after 2016 is 👀
Political hostility, high visa fees and (in the case of the UK) stagnant incomes are making the UK and US less attractive destinations for top international talent.
That steep decline in the appeal of moving to the US after 2016 is 👀
Reposted by Amro Hussien
At #EMBC2025, Dame Molly Stevens shared how bioengineered materials are transforming healthcare - from affordable diagnostics to advanced therapeutics and regenerative medicine.
🔗 https://www.youtube.com/watch?v=id8x8f8IcDU?utm_source=bluesky&utm_medium=social
#Bioengineering #Biomaterials
🔗 https://www.youtube.com/watch?v=id8x8f8IcDU?utm_source=bluesky&utm_medium=social
#Bioengineering #Biomaterials
Next-Gen Biomaterials in Medicine with Prof. Dame Molly Stevens | EMBC 2025 Interview by EMBS TV
From early disease detection to advanced therapies, bioengineering and nanomaterials are revolutionizing medicine. In this exclusive EMBC 2025 interview, Professor Dame Molly Stevens, a world leader in biomaterials research, shares how her team is developing innovative materials that improve diagnostics, enable regenerative medicine, and create smarter therapeutics.
Discover how these breakthroughs are making healthcare more accessible worldwide, reducing diagnostic costs, and shaping the future of personalized medicine. Plus, learn why interdisciplinary collaboration across chemistry, physics, and computer science is key to solving some of the most complex health challenges.
What You'll Learn in This Video:
✔ How biomaterials improve disease detection and therapy
✔ The role of nanotechnology in regenerative medicine
✔ Why affordability and accessibility in diagnostics matter
✔ Cutting-edge research in brain-interactive materials
✔ The vision for the next decade of bioengineering innovation
Timestamps:
00:00 Introduction
00:18 Meet Professor Molly Stevens
00:30 How biomaterials impact healthcare
01:05 Ensuring equal access to diagnostics
01:53 Next-generation diagnostics and affordability
02:29 Future outlook: Advanced therapies and brain-interactive materials
#BiomedicalEngineering #BioMaterials #Nanotechnology #HealthcareInnovation #EMBC2025 #MedicalDiagnostics #RegenerativeMedicine #IEEEEMBS
youtu.be
October 8, 2025 at 6:47 PM
At #EMBC2025, Dame Molly Stevens shared how bioengineered materials are transforming healthcare - from affordable diagnostics to advanced therapeutics and regenerative medicine.
🔗 https://www.youtube.com/watch?v=id8x8f8IcDU?utm_source=bluesky&utm_medium=social
#Bioengineering #Biomaterials
🔗 https://www.youtube.com/watch?v=id8x8f8IcDU?utm_source=bluesky&utm_medium=social
#Bioengineering #Biomaterials
Reposted by Amro Hussien
Excited to share our new paper in Nature Communications! We show how Piezo1 and the molecular clutch work together to sense viscoelastic cues in stem cells. Grateful to my mentors and co-authors from @uofglasgow.bsky.social & @ibecbarcelona.eu who made this possible! Check it out: rdcu.be/eK8d4
Piezo1 regulates the mechanotransduction of soft matrix viscoelasticity
Nature Communications - Matrix viscoelasticity regulates cell behavior in a stiffness-dependent manner. Here, the authors reveal that the mechanosensitive channel Piezo1 transduces soft matrix...
rdcu.be
October 17, 2025 at 5:12 PM
Excited to share our new paper in Nature Communications! We show how Piezo1 and the molecular clutch work together to sense viscoelastic cues in stem cells. Grateful to my mentors and co-authors from @uofglasgow.bsky.social & @ibecbarcelona.eu who made this possible! Check it out: rdcu.be/eK8d4
Reposted by Amro Hussien
RESEARCH | G Wang, M Giera, @trabelink.bsky.social et al (LUMC)
Workflow: Perform quantitative MS imaging and provide insight into spatial metabolic remodeling in ischemic mouse brains 🧪
Workflow: Perform quantitative MS imaging and provide insight into spatial metabolic remodeling in ischemic mouse brains 🧪
Spatial quantitative metabolomics enables identification of remote and sustained ipsilateral cortical metabolic reprogramming after stroke - Nature Metabolism
Wang et al. report a workflow to perform quantitative mass spectrometry imaging and provide insight into spatial metabolic remodelling undergone in the mouse brain upon ischaemia.
bit.ly
October 11, 2025 at 4:00 PM
RESEARCH | G Wang, M Giera, @trabelink.bsky.social et al (LUMC)
Workflow: Perform quantitative MS imaging and provide insight into spatial metabolic remodeling in ischemic mouse brains 🧪
Workflow: Perform quantitative MS imaging and provide insight into spatial metabolic remodeling in ischemic mouse brains 🧪
Reposted by Amro Hussien
The surprisingly lifelike behavior of inanimate chemicals & systems forces us to reconsider our assumptions about where minds reside, @conorfeehly.bsky.social writes.
#biology #cognition #chemistry #ool
#biology #cognition #chemistry #ool
The Surprisingly Lifelike Behavior Of Mindless Material | NOEMA
New ways of studying the origin of life are leading to a better understanding of consciousness and the mind.
www.noemamag.com
October 9, 2025 at 5:24 PM
The surprisingly lifelike behavior of inanimate chemicals & systems forces us to reconsider our assumptions about where minds reside, @conorfeehly.bsky.social writes.
#biology #cognition #chemistry #ool
#biology #cognition #chemistry #ool
Reposted by Amro Hussien
How do #stemcells integrate information to coordinate fate decisions? Delighted to finally see our work showing how growth factors regulate the mechano-osmotic state of the #nucleus and #chromatin to control #pluripotency exit out! www.nature.com/articles/s41... see 🧵 👇
Mechano-osmotic signals control chromatin state and fate transitions in pluripotent stem cells - Nature Cell Biology
McCreery, Stubb et al. show that mechano-osmotic changes in the nucleus induce general transcriptional repression and prime chromatin for cell fate transitions by relieving repression of specific differentiation genes.
www.nature.com
September 29, 2025 at 4:45 PM
How do #stemcells integrate information to coordinate fate decisions? Delighted to finally see our work showing how growth factors regulate the mechano-osmotic state of the #nucleus and #chromatin to control #pluripotency exit out! www.nature.com/articles/s41... see 🧵 👇
Reposted by Amro Hussien
Gene-editing tools transform cells into record-keepers, capturing hidden timelines of health and disease
go.nature.com/4pBRRlh
go.nature.com/4pBRRlh
Real-time molecular recorders expose the inner lives of cells
Gene-editing tools transform cells into record-keepers, capturing hidden timelines of health and disease.
go.nature.com
September 22, 2025 at 5:39 PM
Gene-editing tools transform cells into record-keepers, capturing hidden timelines of health and disease
go.nature.com/4pBRRlh
go.nature.com/4pBRRlh