Journal of Cell Biology
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Journal of Cell Biology
@jcb.org
Journal of Cell Biology publishes peer-reviewed research on all aspects of cellular structure and function. Published by Rockefeller University Press @rupress.org
🌐 https://rupress.org/jcb
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Our annual collection highlights 13 of the year's most impactful papers that have garnered exceptional interest from our readership. Explore cutting-edge findings spanning the diverse spectrum of cell biology 👉 rupress.org/jcb/collecti...

#CellBio2025
@ascbiology.bsky.social
Developmentally regulated #actin-#microtubule crosstalk in #Drosophila #oogenesis. New study from Wei-Chien Chou, Brooke M. McCartney and colleagues @cmu.edu: rupress.org/jcb/article/...

#Cytoskeleton #Development
January 16, 2026 at 8:45 PM
🎨 Download JCB's CELLULAR DIVERSITY poster! 📩 Sign up to receive our future special collections and download this beautiful artwork by Bianca Dunn to display at home or in the lab 👉 info.rupress.org/jcb-collecti...
January 16, 2026 at 5:15 PM
#Keratin 15 promotes a progenitor cell state in basal #keratinocytes of skin #epidermis. say Catherine J. Redmond, Pierre A. Coulombe and colleagues @umich.edu: rupress.org/jcb/article/...

#Cytoskeleton #StemCells
January 16, 2026 at 3:45 PM
#Condensin II collaborates with #cohesin to establish and maintain #interphase #chromosome territories, say Takao Ono, Tatsuya Hirano (Riken) and colleagues: rupress.org/jcb/article/...

#CellCycle #Biochemistry #Chromatin
January 16, 2026 at 2:30 PM
Reposted by Journal of Cell Biology
To all lipid-curious cell biologists: check out this comprehensive overview of lipid-based methods by @gerryhammond.bsky.social and colleagues in @jcb.org — a school of Babel fish for #lipidtime:

rupress.org/jcb/article/...
The cell biologist’s guide to detecting and modulating membrane phospholipids | Journal of Cell Biology | Rockefeller University Press
Worcester et al. describe a suite of molecular tools and approaches that can be used to probe and experimentally study lipids.
rupress.org
January 3, 2026 at 12:30 PM
🌐 Early registration deadline is approaching for @keystoneSymposia.bsky.social meeting, #Aging: #Immune Function & #OrganHealth, March 22-25 in Banff 🏔️
Register here 👉 www.keystonesymposia.org/conferences/...

#KSAging26
January 15, 2026 at 4:15 PM
🌐 Early registration deadline is approaching for @keystoneSymposia.bsky.social meeting, #InnateImmunity: Diversity in #HostDefense & Disease, March 22-25 in Banff 🏔️
Register here 👉 www.keystonesymposia.org/conferences/...

#KSInnateImmune26
January 15, 2026 at 4:01 PM
Mitochondrial presequences harbor variable strengths to maintain organellar function. New study from Youmian Yan, Natalie Niemi (@nieminm.bsky.social) et al. @washumedicine.bsky.social: rupress.org/jcb/article/...

@ianofbristol.bsky.social
#Biochemistry #CellMetabolism #Organelles #Mitochondria
January 15, 2026 at 3:45 PM
HP1 isoforms direct repair pathway choice in response to #heterochromatin double-strand breaks. New study from Darshika Bohra and Aprotim Mazumder @tifrhyderabad.bsky.social: rupress.org/jcb/article/...

#Chromatin #epigenetics #DNAbiology #DNArepair
January 14, 2026 at 9:45 PM
Plasma membrane-to-lysosome FGR signaling regulates #endocytosis-associated #lysosome homeostasis, say Qiuyuan Yin, Chonglin Yang and colleagues (Yunnan University): rupress.org/jcb/article/...

#Organelles #Lysosomes
January 14, 2026 at 9:15 PM
A Syd and RUFY #dynein adaptor complex mediates axonal circulation of dense core vesicles, say Viktor Karlovich Lund, Ole Kjaerulff and colleagues @ucph.bsky.social: rupress.org/jcb/article/...

#Trafficking #StructuralBiology #Neuroscience
January 14, 2026 at 8:45 PM
Rsp5/NEDD4 and #ESCRT regulate TDP-43 toxicity and turnover via an endolysosomal clearance mechanism. New study from Aaron Byrd, Lucas J. Marmorale, Ross Buchan and colleagues @uarizona.bsky.social: rupress.org/jcb/article/...

#ProteinHomeostasis #Genetics #Trafficking #Neuroscience #ALS
January 14, 2026 at 8:45 PM
Regulation of the #formin #INF2 by #actin monomers and calcium-#calmodulin. New study from Miriam Lee, Aiman Jalmukhambetova, T. Emme Burgin, and Henry N. Higgs (Geisel School of Medicine): rupress.org/jcb/article/...

#Cytoskeleton #Biochemistry #CellBiology #ActinDynamics
January 14, 2026 at 8:15 PM
Stage- and tissue-specific gene editing using 4-OHT inducible Cas9 in whole organism. New study from Yaqi Li, Weiying Zhang, Zihang Wei, Anming Meng, Xiaotong Wu @tsinghuauniversity.bsky.social and colleagues: rupress.org/jcb/article/...

#Development #DNAbiology #CRISPR #Zebrafish
January 14, 2026 at 8:01 PM
The traffic controller: GARLH4 dictates neuroligin #synapse-type preference. Eunjoon Kim (Korea Advanced Institute of Science and Technology (KAIST)) discusses recent work from Yamasaki et al. (rupress.org/jcb/article/...) in Spotlight: rupress.org/jcb/article/...

#Neuroscience
January 14, 2026 at 7:30 PM
A Rab1 interactome illuminates a dual role in #autophagy and membrane #trafficking, say Alexander R. van Vliet, Sean Munro and colleagues @mrclmb.bsky.social: rupress.org/jcb/article/...
January 14, 2026 at 4:02 PM
🌐 Explore emerging research with field leaders @keystoneSymposia.bsky.social #Membrane Dynamics, Repair & Disease, Feb 02–05 in Keystone🌲 JCB's Scientific Editor Dan Simon will be attending!
Register now 👉 www.keystonesymposia.org/conferences/...

#KSMembrane26
January 14, 2026 at 3:00 PM
🌐 Explore emerging research with field leaders @keystoneSymposia.bsky.social #Autophagy: Mechanisms to Therapy, Feb 02–05 in Keystone🌲 JCB's Scientific Editor Dan Simon will be attending!
Register now 👉 www.keystonesymposia.org/conferences/...

#KSAutophagy26
January 14, 2026 at 2:45 PM
The #adipose tissue has an apical-basal #polarity required for Col IV-dependent cell-cell #adhesion. New study from Jameela Almasoud, Cyril Andrieu, Bren Hunyi Lee, and Anna Franz @ucl-cdb.bsky.social @ucl.ac.uk: rupress.org/jcb/article/...

#Development #Drosophila #Ecdysone #Collagen
January 14, 2026 at 2:30 PM
Endoplasmic reticulum patterns insect cuticle nanostructure. New study from Sachi Inagaki, Shigeo Hayashi @riken-bdr.bsky.social and colleagues: rupress.org/jcb/article/...

🎦 See video summary by Sachi Inagaki 👉 youtu.be/50JRPysrTNU

#Drosophila #ER_literature #Development #Organelles
January 13, 2026 at 9:01 PM
In a screen to identify mutants that delay the decline in #mitochondria function with #aging, Waite, Gottschling et al. discover that potassium, the most abundant cation in cells, modulates mitochondrial membrane potential—a functional hallmark of mitochondrial health. rupress.org/jcb/article/...
January 13, 2026 at 5:30 PM
CRM1 inhibits NPAT condensation and #histone locus body formation via a competitive occupation strategy. New study from Xiao Xia Cong, Shui Bo Xu, Wen Kai Zou, Xiu Kui Gao, Xiaohui Zou, Yi Ting Zhou, Li Ling Zheng (Zhejiang University) and colleagues: rupress.org/jcb/article/...

#Biocondensates
January 13, 2026 at 4:15 PM
Mechanically gated OSCA/TMEM63 #IonChannels: From physiological function to structural basis. New review from Siqi Deng, Qinling Qiu, Shangyu Dang (Hong Kong University of Science and Technology), and Zhiqiang Yan (Capital Medical University, Beijing)
rupress.org/jcb/article/...

#Physiology
January 13, 2026 at 3:30 PM
Cell-type-specific spatiotemporal control of GFP-tagged protein degradation in mice. New study from Alexandra Prado-Mantilla, Terry Lechler @terrylechler.bsky.social and colleagues @duke-university.bsky.social: rupress.org/jcb/article/...

#Technology #ProteinHomeostasis
January 13, 2026 at 3:04 PM
The cell biologist’s guide to detecting and modulating membrane #phospholipids. New review from Michael Worcester, Gerald Hammond @gerryhammond.bsky.social and colleagues: rupress.org/jcb/article/...

#Methods #Reproducibility #Membrane #lipid #Biochemistry #Cancer
January 13, 2026 at 2:45 PM