Journal of Cell Biology
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Journal of Cell Biology
@jcb.org
9.7K followers 1.8K following 600 posts
Journal of Cell Biology publishes peer-reviewed research on all aspects of cellular structure and function. Published by Rockefeller University Press @rupress.org
🌐 https://rupress.org/jcb
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jcb.org
Yang, Kong, Liu et al. report that homocysteine, an intermediate in methionine-cysteine #metabolism and the cause of the life-threatening disease #homocystinuria, disrupts lysosomal functions by binding to and homocysteinylating V-ATPase. rupress.org/jcb/article/...

#lysosomes
November 25, 2025 at 7:00 PM
jcb.org
🎉 Congratulations to Yu Deng, winner of the 2025 Norton B. Gilula Travel Award! Yu is a PhD student from Dr. Peter Devreotes’ lab at @jhu.edu. Be sure to catch Yu’s talk during #CellBio2025!
Read about this year's winners 👉 rupress.org/jcb/pages/al...
November 24, 2025 at 3:30 PM
jcb.org
🎉 Congratulations to Justus Francis (@justusfrancis.bsky.social), winner of the 2025 Alan Hall Travel Award! Justus is a graduate student in @sc-lab.bsky.social. Be sure to catch Justus’s talk during #CellBio2025!
Read about this year's winners 👉 rupress.org/jcb/pages/al...
November 24, 2025 at 3:15 PM
jcb.org
Xun Cao, Yiming Peng, Mengyuan Yang, Daisuke Takao and colleagues (Huazhong Agricultural University) present a high-content image-based phenotyping pipeline for quantitative analysis of organelle morphology. rupress.org/jcb/article/...
November 21, 2025 at 8:15 PM
jcb.org
Liu et al. discover that pathogenic bacteria use a shared strategy to exploit the host’s cellular recycling process, #mitophagy. Through an effector protein that acts as an external receptor, bacteria suppress inflammatory responses to promote #infection rupress.org/jcb/article/...
#Autophagy
November 21, 2025 at 5:45 PM
jcb.org
Xingchen Li, Christoph Ballestrem, et al. @mcrcellmatrix.bsky.social show that multidomain interactions between talin and tensin3 regulate #integrin activity, fibrillar #adhesion formation, #fibronectin assembly, and mechanosensitive tensin3 phase separation. rupress.org/jcb/article/...
November 21, 2025 at 5:00 PM
jcb.org
Explore new insights into the biology of axon-carrying–dendrite neurons, the role of mitochondrial fission in astrocyte morphogenesis, and the regulation of membrane contact sites in photoreceptors, as well as a new framework for synaptic vesicle segmentation 👉 rupress.org/jcb/collecti...
November 21, 2025 at 3:30 PM
jcb.org
Actin arginylation alters myosin engagement and F-actin patterning despite structural conservation, say Clyde Savio Pinto, Saskia E. Bakker, Andrejus Suchenko, Masanori Mishima, Mohan Balasubramanian @sporemohan.bsky.social and colleagues: rupress.org/jcb/article/...
November 21, 2025 at 2:45 PM
jcb.org
Actomyosin contractility and a threshold of cadherin cell adhesion is required during tissue fusion, say Camilla Teng @xsciteng.bsky.social, Jeffrey Bush @jeffbush.bsky.social and colleagues @ctbatucsf.bsky.social: rupress.org/jcb/article/...

#Development #Adhesion
November 20, 2025 at 7:45 PM
jcb.org
📢 Attention #EESNucleus attendees! TODAY (Nov. 20) at 12:10 - 1:40 pm (CET): Join @jcb.org Scientific Editor Gabriele Stephan at the Meet the Editor session during lunchtime! www.embl.org/about/info/c...

#EESNucleus @events.embl.org
November 20, 2025 at 9:01 AM
jcb.org
Wang, Kim, Ding et al. of the Qing Deng lab demonstrate that inward-rectifying potassium channels maintain the resting membrane potential and are required for directional sensing during #neutrophil chemotaxis. rupress.org/jcb/article/...
November 19, 2025 at 6:15 PM
jcb.org
Joly & @ccdlab.bsky.social reveal how the enzyme Katanin prevents wasting energy during microtubule remodeling. They show how Katanin links activation to microtubule binding, avoiding unnecessary ATP consumption & providing insights important for cell biology & disease. rupress.org/jcb/article/...
November 19, 2025 at 5:00 PM
jcb.org
Final day at #SfN25! If you're in San Diego, stop by @rupress.org booth #3719 to discuss your research and our journal! Don't forget to pick up our #Neuroscience Collection magazine 📚 We look forward to meeting you! 💬 💡
November 19, 2025 at 4:15 PM
jcb.org
Sensing danger at the bridge. Juan Martin-Serrano (@juanmartin-serrano.bsky.social) @kingscollegelondon.bsky.social discusses new work from Dam, Moreno, Brownlow, @longchrom.bsky.social and colleagues (rupress.org/jcb/article/...), in Spotlight: rupress.org/jcb/article/...
#Cytokinesis
November 19, 2025 at 2:45 PM
jcb.org
Reevaluating the roles of PPARs and nuclear receptors in human #peroxisome biology. New Viewpoint from Fred Mast (@fredmast.bsky.social), Richard Rachubinski, and John Aitchison @seattlechildrens.org: rupress.org/jcb/article/...

#Organelles #Development #Metabolism #CellSignaling #Peroxisomes
November 18, 2025 at 8:15 PM
jcb.org
Wenjing Long, Yanshan Fang et al. reveal that SCFFBXO21-mediated ubiquitination and degradation of NMNAT2 regulates axon survival in nerve injury. rupress.org/jcb/article/...

📕 In Cellular Neurobiology collection: rupress.org/jcb/collecti...
#SfN25
November 18, 2025 at 4:15 PM
jcb.org
Attending #SfN25 in San Diego? Stop by @rupress.org booth #3719 to discuss your research and our journal! Don't forget to pick up our #Neuroscience Collection magazine 📚 We look forward to meeting you! 💬 💡
November 18, 2025 at 3:45 PM
jcb.org
@biljanaermanoska.bsky.social, Baets, and @rodallab.bsky.social show that nonmuscle myosin II regulates presynaptic actin and neuronal mechanobiology in #Drosophila. rupress.org/jcb/article/...

📕 In Cellular Neurobiology collection: rupress.org/jcb/collecti...
#SfN25
November 17, 2025 at 4:15 PM
jcb.org
Adapting plasma membrane for mitotic cell rounding through Aurora A phosphorylation of numb. New Study from Yanyan Li, Ke Liu, Xian Lin, Zhihao Ding, Ximing Shao, Hongchang Li (Shenzhen Institutes of Advanced Technology) and colleagues: rupress.org/jcb/article/...

#CellCycle #CellDivision #Mitosis
November 17, 2025 at 3:15 PM
jcb.org
Attending #SfN25 in San Diego? JCB's Executive Editor Tim Spencer will be available for a chat TODAY (Monday) 1:30pm - 2:30pm ! Stop by @rupress.org booth #3719 to discuss your research with Tim and learn about JCB's publication process! 🧠 📝

See our collection: rupress.org/jcb/collecti...
November 17, 2025 at 3:15 PM
jcb.org
Attending #SfN25 in San Diego? Visit @rupress.org booth #3719 to chat about the journal and pick up our #Neuroscience Collection magazine 📚 as well as an exclusive pouch! 🎁 We look forward to meeting you! 💬 💡
November 17, 2025 at 3:00 PM
jcb.org
Men, Hirayama, Murata et al. show that misfolded protein aggregates are degraded through #microautophagy, a process mediated by the UBAP1-containing ESCRT-I complex and PTPN23. rupress.org/jcb/article/...

📕 In Cellular Neurobiology collection: rupress.org/jcb/collecti...
#SfN25
November 16, 2025 at 6:15 PM
jcb.org
Khosrozadeh, @benoitzuber.bsky.social et al. developed CryoVesNet, which enables accurate segmentation of synaptic vesicles in cryo-electron tomograms. rupress.org/jcb/article/...

📕 In Cellular Neurobiology collection: rupress.org/jcb/collecti...
#SfN25
November 16, 2025 at 4:15 PM
jcb.org
Han, Grünewald, Mikhaylova et al. use primary hippocampal cultures to demonstrate that neurons with axon-carrying–dendrite (AcD) morphology can develop independent of an in vivo environment. rupress.org/jcb/article/...

📕 In Cellular Neurobiology collection: rupress.org/jcb/collecti...
#SfN25
November 15, 2025 at 6:15 PM
jcb.org
Rodriguez Salazar, @caglaeroglu.bsky.social et al. show that Drp1-mediated mitochondrial fission is necessary for peripheral #astrocyte process formation. rupress.org/jcb/article/...

📕 In Cellular Neurobiology collection: rupress.org/jcb/collecti...
#SfN25
November 15, 2025 at 4:15 PM