Ahmed Hasan
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ahmedrhasan.bsky.social
Ahmed Hasan
@ahmedrhasan.bsky.social
Bioinformatics, functional genomics, software eng, some ML. Formerly PhD in pop gen of recombination rate variation at UToronto. Digs #rstats, Python, open science, vim bindings, guitars.

1/2 of Red Graves:
redgraves.ampwall.com
redgraves.bandcamp.com
Reposted by Ahmed Hasan
evergreen
November 22, 2025 at 5:20 PM
Reposted by Ahmed Hasan
Extremely upset that a throw-away XKCD joke somehow became the organizing principle for the Internet.
November 20, 2025 at 2:31 AM
Reposted by Ahmed Hasan
this is theranos-level fraud, but everyone with the power to do anything about it is on the take, apparently
Anthropic CEO Dario Amodei thinks AI could help find cures for most cancers, prevent Alzheimer’s, and even double the human lifespan. cbsn.ws/4oRZ8Nm
November 17, 2025 at 1:22 AM
Reposted by Ahmed Hasan
if microsoft just made outlook search not suck they'd see triple the productivity gains of any AI integration
November 14, 2025 at 12:18 AM
Reposted by Ahmed Hasan
"The mainstream understanding of AI is as an interefering piece of shit which doesn't work" pt II

www.askamanager.org/2025/11/the-...
November 12, 2025 at 8:47 PM
Reposted by Ahmed Hasan
‘Study after study shows that students want to develop these critical thinking skills, are not lazy, and large numbers of them would be in favor of banning ChatGPT and similar tools in universities’, says @olivia.science www.ru.nl/en/research/...
‘Opposing the inevitability of AI at universities is possible and necessary’ | Radboud University
Since the widespread release of ChatGPT in December of 2022, AI has taken over much of the world by storm – including academia. Most of this happened with very little pushback, despite a myriad of iss...
www.ru.nl
November 1, 2025 at 10:26 PM
Reposted by Ahmed Hasan
www.nbcnews.com/tech/tech-ne...
According to the study, a significant number of top-tier benchmarks fail to define what exactly they aim to test, concerningly reuse data and testing methods from pre-existing benchmarks, and seldom use reliable statistical methods to compare results between models.
AI's capabilities may be exaggerated by flawed tests, according to new study
A study from the Oxford Internet Institute analyzed 445 tests used to evaluate AI models.
www.nbcnews.com
November 8, 2025 at 5:56 PM
Reposted by Ahmed Hasan
In case anyone is wondering if Watson was really THAT bad, @lpachter.bsky.social compiled a list of quotes that are absolutely not for the faint of heart.
liorpachter.wordpress.com/2018/05/18/j...
November 7, 2025 at 10:18 PM
Reposted by Ahmed Hasan
My favorite comment on the FT story
November 6, 2025 at 7:49 PM
Reposted by Ahmed Hasan
bro are you fucking kidding me
November 6, 2025 at 5:59 PM
Reposted by Ahmed Hasan
The extent to which AI FOMO is warping people's decisions is rather stunning, actually. I can see why the Anthropics and Googles would want this, but the other tech co managers going along with it ...
It seems like the only way tech companies are able to compel AI usage is by coercion in performance review processes?

(via The Information "AI Agenda" newsletter)
October 30, 2025 at 2:34 PM
Reposted by Ahmed Hasan
When people learn with ChatGPT instead of following their own searches, they end up knowing less, caring less, and producing worse advice, even when the facts are the same.

Friction is an essential ingredient for learning! Convenience makes us shallow.

academic.oup.com/pnasnexus/ar...
Experimental evidence of the effects of large language models versus web search on depth of learning
Abstract. The effects of using large language models (LLMs) versus traditional web search on depth of learning are explored. A theory is proposed that when
academic.oup.com
October 28, 2025 at 3:14 PM
Reposted by Ahmed Hasan
We need to have a conversation about random seeds. Don't use 42.
blog.genesmindsmachines.com/p/if-your-ra...
If your random seed is 42 I will come to your office and set your computer on fire🔥
Figuratively. More likely you'll get a stern talking to.
blog.genesmindsmachines.com
October 22, 2025 at 12:49 PM
Reposted by Ahmed Hasan
We. Told. You. So. But also, that "May Rely" in the significance section ( 👇🏾 ) is *way* too… let's go with "generous;" lexical associations and statistical priors are what these systems are literally made of, and all that they do. Literally. doi.org/10.1073/pnas...
October 17, 2025 at 7:23 PM
Reposted by Ahmed Hasan
I am convinced that Microsoft is run by people who do not interact with digital devices. Somebody holds up a computer and uses it for Satya Nadella, he just sits and scratches his chin and says “make it do more”
LMAOOO WHAT DO YOU MEAN THE NEW XBOX HANDHELD COMES WITH MICROSOFT TEAMS AND ONEDRIVE INSTALLED??? this is the fucking goofiest company in games
October 16, 2025 at 4:24 AM
Reposted by Ahmed Hasan
i think about this post every time i watch a movie
September 28, 2025 at 2:42 AM
Reposted by Ahmed Hasan
CHOTINER: This game you like to play, what's it called?

ME: Slay the Spire.

CHOTINER: And you play it on the computer?

ME: Yeah. Well, I also have it on my phone. I played another 300 hours.

CHOTINER: And these other games in your Steam library. Have you finished them?

ME: Now hold on a second,
September 23, 2025 at 7:21 PM
Reposted by Ahmed Hasan
Ahmed just stumbled on a Substack article written in spanish with a positive review of Nighttime Heists/Daytime Getaways written by a total stranger this is such an incredible feeling :' ) I love making music

www.hipersonica.com/p/el-volquet...
El volquete del metal #71: Deafheaven tomaron una mesa
Los discos de metal que tienes que escuchar
www.hipersonica.com
September 16, 2025 at 7:54 PM
Reposted by Ahmed Hasan
Doomscrolling pause to chat CRISPR libraries! Preprint describes our new, data-driven approach to combine on-target and off-target predictions much more intelligently for *selecting* guides, which we use to develop our newest Cas9 knockout library, Jacquere. Thread: www.biorxiv.org/content/10.1...
Balancing off-target and on-target considerations for optimized Cas9 CRISPR knockout library design
The continued development of high-dimensional CRISPR screen readouts, such as single-cell RNA sequencing and high-content imaging, necessitates compact libraries to enable functional interrogation at ...
www.biorxiv.org
September 7, 2025 at 5:02 PM
Reposted by Ahmed Hasan
UNLIMITED VELOCITY
September 7, 2025 at 4:25 PM
Reposted by Ahmed Hasan
Academic authors, here's a peek into the black box of journal publishing from an journal editor if you can bear it:
September 6, 2025 at 11:09 PM
Reposted by Ahmed Hasan
Excellent. "If you’re pushing slop or eating it, you wouldn’t read it anyway. You’d ask a bot for a summary and forget what it told you, then proceed with your day, unchanged by words you did not read and ideas you did not consider."

Everyone else, please read.
I considered writing a long carefully constructed argument laying out the harms and limitations of AI, but instead I wrote about being a hater. Only humans can be haters.
I Am An AI Hater
I am an AI hater. This is considered rude, but I do not care, because I am a hater.
anthonymoser.github.io
August 28, 2025 at 1:43 PM
Reposted by Ahmed Hasan
HEY friends: recently seen heaps of "disclosures" from AI companies of the energy cost per question you type into chatbots (most recently from Google)?

Presenting per-query 'efficiency' is part of big tech's efforts to hide its extremely real and happening-right-now climate impacts!

NEW POST -->>>
Big tech’s selective disclosure masks AI’s real climate impact
Google claims to have disclosed new information proving its own efficiency. But it has hidden the bigger picture. Guess what: I’ve got the bigger picture for you right here in this big old po…
ketanjoshi.co
August 22, 2025 at 10:07 PM
Reposted by Ahmed Hasan
Hey everybody! @drjuliawester.bsky.social and I have a new paper!

We surveyed over 800 scientists, science communicators, and science educators who use social media.

Conclusion: Scientists no longer find Twitter useful or pleasant, and many have switched to Bluesky! 🧪🌎🦑

doi.org/10.1093/icb/...
Scientists no Longer Find Twitter Professionally Useful, and have Switched to Bluesky
Synopsis. Social media has become widely used by the scientific community for a variety of professional uses, including networking and public outreach. For
doi.org
August 19, 2025 at 2:34 PM