Teddy Yewdell
@tyewdell.bsky.social
B cells | plasma cells |autoimmunity | MS | IBD | lupus | immune memory | tiki taka | geggenpressing | Group Leader/Principal Scientist at Genentech
https://www.gene.com/scientists/our-scientists/teddy-yewdell
https://www.gene.com/scientists/our-scientists/teddy-yewdell
Don't forget to sign up for the B cell-T cell/plasma cell Joint Keystone meeting - short talk abstracts due 11/13 - hope to see you there!
September 24, 2025 at 4:50 PM
Don't forget to sign up for the B cell-T cell/plasma cell Joint Keystone meeting - short talk abstracts due 11/13 - hope to see you there!
Reposted by Teddy Yewdell
Excited to share our study describing a role for a subset of Thetis cells, TC IV, in tolerance to food antigens. A team effort led by Vanja Cabric and Yollanda Parisotto
www.science.org/doi/10.1126/...
www.science.org/doi/10.1126/...
A wave of Thetis cells imparts tolerance to food antigens early in life
Within the intestine, peripherally-induced regulatory T (pTreg) cells play an essential role in suppressing inflammatory responses to food proteins. However, the identity of antigen-presenting cells (...
www.science.org
May 21, 2025 at 6:24 PM
Excited to share our study describing a role for a subset of Thetis cells, TC IV, in tolerance to food antigens. A team effort led by Vanja Cabric and Yollanda Parisotto
www.science.org/doi/10.1126/...
www.science.org/doi/10.1126/...
“We all said to each other, ‘This is the most significant thing we have ever done.” An amazing story, and yet one that does not happen without federally funded basic research www.nytimes.com/2025/05/15/h...
www.nytimes.com
May 15, 2025 at 8:59 PM
“We all said to each other, ‘This is the most significant thing we have ever done.” An amazing story, and yet one that does not happen without federally funded basic research www.nytimes.com/2025/05/15/h...
Andor is really freaking me out - impeccable timing!
May 15, 2025 at 6:16 AM
Andor is really freaking me out - impeccable timing!
Reposted by Teddy Yewdell
'I did not complete a customs declaration for frog embryos (...) this would normally result in a warning or fine. Instead, my visa was revoked & I was sent to a detention center in Louisiana, where I have spent the past 3 months with roughly 100 other women. We share one room w dormitory-style beds'
Opinion | I Came to Study Aging. Now I’m Trapped in ICE Detention.
www.nytimes.com
May 14, 2025 at 4:27 AM
'I did not complete a customs declaration for frog embryos (...) this would normally result in a warning or fine. Instead, my visa was revoked & I was sent to a detention center in Louisiana, where I have spent the past 3 months with roughly 100 other women. We share one room w dormitory-style beds'
Reposted by Teddy Yewdell
Just deranged. This was a *solved* problem.
May 2, 2025 at 8:45 PM
Just deranged. This was a *solved* problem.
Reposted by Teddy Yewdell
Reposted by Teddy Yewdell
Published an op-ed for @cnn.com: “Nobel laureate: I owe America my success. Today, its scientific future is in danger.”
A personal reflection on what’s at stake as science funding gets slashed. I’d be grateful if you could amplify both in and beyond the science world.
www.cnn.com/2025/04/09/h...
A personal reflection on what’s at stake as science funding gets slashed. I’d be grateful if you could amplify both in and beyond the science world.
www.cnn.com/2025/04/09/h...
Nobel laureate: I owe America my success. Today, its scientific future is in danger | CNN
Dr. Ardem Patapoutian says he watches “with deep sadness as the United States’ remarkable scientific enterprise, which took generations of hard work and national investment to build, faces a concerted...
www.cnn.com
April 9, 2025 at 11:30 AM
Published an op-ed for @cnn.com: “Nobel laureate: I owe America my success. Today, its scientific future is in danger.”
A personal reflection on what’s at stake as science funding gets slashed. I’d be grateful if you could amplify both in and beyond the science world.
www.cnn.com/2025/04/09/h...
A personal reflection on what’s at stake as science funding gets slashed. I’d be grateful if you could amplify both in and beyond the science world.
www.cnn.com/2025/04/09/h...
Love this, and also kinda sad we are done with strollers… I’m not crying, you’re crying!!! www.nytimes.com/2025/04/12/s...
The Brooklyn Stroll Club Has Brought Together Fathers in Search of Friendship
For fathers in search of friendship, a growing group has emerged: the Brooklyn Stroll Club.
www.nytimes.com
April 14, 2025 at 1:54 AM
Love this, and also kinda sad we are done with strollers… I’m not crying, you’re crying!!! www.nytimes.com/2025/04/12/s...
Reposted by Teddy Yewdell
www.nytimes.com/2025/04/03/o...
Really important piece to share widely. Too many Americans don’t know how severe a threat this Administration poses to our scientific infrastructure, global leadership, and health security
Really important piece to share widely. Too many Americans don’t know how severe a threat this Administration poses to our scientific infrastructure, global leadership, and health security
Opinion | The Uncertain Fate of the Young American Scientist (Gift Article)
Young researchers are choosing between staying in science and staying in the United States.
www.nytimes.com
April 4, 2025 at 7:32 AM
www.nytimes.com/2025/04/03/o...
Really important piece to share widely. Too many Americans don’t know how severe a threat this Administration poses to our scientific infrastructure, global leadership, and health security
Really important piece to share widely. Too many Americans don’t know how severe a threat this Administration poses to our scientific infrastructure, global leadership, and health security
Reposted by Teddy Yewdell
Great to have our paper out in @pnas.org showing that lung B cells in ectopic germinal centers undergo affinity maturation.
@smguillaume.bsky.social @wsfoster.bsky.social @sanmarti92.bsky.social @emae-watson.bsky.social Silvia Innocentin, Grant Kennedy & Alice Denton. doi.org/10.1073/pnas...
@smguillaume.bsky.social @wsfoster.bsky.social @sanmarti92.bsky.social @emae-watson.bsky.social Silvia Innocentin, Grant Kennedy & Alice Denton. doi.org/10.1073/pnas...
Lung B cells in ectopic germinal centers undergo affinity maturation | PNAS
The lungs are constantly exposed to the external environment and a myriad of antigenic
challenges within the air. Chronic exposure to allergens and...
doi.org
April 3, 2025 at 3:03 AM
Great to have our paper out in @pnas.org showing that lung B cells in ectopic germinal centers undergo affinity maturation.
@smguillaume.bsky.social @wsfoster.bsky.social @sanmarti92.bsky.social @emae-watson.bsky.social Silvia Innocentin, Grant Kennedy & Alice Denton. doi.org/10.1073/pnas...
@smguillaume.bsky.social @wsfoster.bsky.social @sanmarti92.bsky.social @emae-watson.bsky.social Silvia Innocentin, Grant Kennedy & Alice Denton. doi.org/10.1073/pnas...
I remember seejng this as a preprint a while ago, incredibly clever analysis, and profound inplications. So much biology to discover in the neuroimmune domain!! www.nature.com/articles/s41...
A natural experiment on the effect of herpes zoster vaccination on dementia - Nature
Using a natural experiment that avoids common bias concerns, this study finds that the live-attenuated shingles vaccine reduced the probability of a new dementia diagnosis within a follow-up period of...
www.nature.com
April 2, 2025 at 6:26 PM
I remember seejng this as a preprint a while ago, incredibly clever analysis, and profound inplications. So much biology to discover in the neuroimmune domain!! www.nature.com/articles/s41...
Reposted by Teddy Yewdell
Call to arms by @lisamjarvis.bsky.social for biopharma to mobilize in support of the engines that power them - federally supported biomedical research and drug evaluation
Noticeably silent amid the upheaval at HHS? Big pharma. Every new drug has NIH somewhere in its DNA--and NIH funding supports the training of their workforce. Now they're finding out FDA isn't safe, either. Wrote about how keeping quiet isn't working My latest @opinion.bloomberg.com (gift link):
Big Pharma Needs to Get Off the Sidelines
The industry can’t continue to sit idly by while Robert F. Kennedy Jr. guts the nation’s public health agencies.
www.bloomberg.com
April 1, 2025 at 5:38 PM
Call to arms by @lisamjarvis.bsky.social for biopharma to mobilize in support of the engines that power them - federally supported biomedical research and drug evaluation
Reposted by Teddy Yewdell
“Internet, vaccines, anything you can think of, were originally developed by publicly funded research programmes, and nobody at the time could have foreseen what would come out of them.”
@marialep.bsky.social
www.irishtimes.com/science/2025...
@marialep.bsky.social
www.irishtimes.com/science/2025...
Irrational view of science under Trump not reflected beyond US, says EU research funder
Prof Maria Leptin rejects view ‘this is a big opportunity to snatch back our colleagues’
www.irishtimes.com
April 2, 2025 at 2:48 PM
“Internet, vaccines, anything you can think of, were originally developed by publicly funded research programmes, and nobody at the time could have foreseen what would come out of them.”
@marialep.bsky.social
www.irishtimes.com/science/2025...
@marialep.bsky.social
www.irishtimes.com/science/2025...
Reposted by Teddy Yewdell
"This is not a left or right moment. It is a right or wrong moment."
-- Senator Cory Booker, today
-- Senator Cory Booker, today
April 2, 2025 at 3:51 AM
"This is not a left or right moment. It is a right or wrong moment."
-- Senator Cory Booker, today
-- Senator Cory Booker, today
Reposted by Teddy Yewdell
Thank you, Cory Booker for defending scientific research. Speaking out against the mindless, tragic loss of economic benefit, our global scientific competitive edge and hope for so many families in health crises so clearly after standing there for 24 hrs is remarkable.
April 1, 2025 at 11:42 PM
Thank you, Cory Booker for defending scientific research. Speaking out against the mindless, tragic loss of economic benefit, our global scientific competitive edge and hope for so many families in health crises so clearly after standing there for 24 hrs is remarkable.
Reposted by Teddy Yewdell
People/organizations with means and a vision for the future of biomedical science - we need an “Arc Institute” equivalent in the DMV area to sponge up all the incredible talent, opportunity of a lifetime for a visionary entrepreneur, I will help! @mcuban.bsky.social
April 1, 2025 at 4:03 PM
People/organizations with means and a vision for the future of biomedical science - we need an “Arc Institute” equivalent in the DMV area to sponge up all the incredible talent, opportunity of a lifetime for a visionary entrepreneur, I will help! @mcuban.bsky.social
Reposted by Teddy Yewdell
"This will go down as one of the darkest days in modern scientific history." Story on the decimation of NIH by @maxkozlov.bsky.social www.nature.com/articles/d41...?
‘One of the darkest days’: NIH purges agency leadership amid mass layoffs
In shock move, four institute directors at the US biomedical agency are removed from their posts.
www.nature.com
April 1, 2025 at 9:11 PM
"This will go down as one of the darkest days in modern scientific history." Story on the decimation of NIH by @maxkozlov.bsky.social www.nature.com/articles/d41...?
Go, @booker.senate.gov , Go!!! We need more like this from our leaders NOW.
April 1, 2025 at 7:39 PM
Go, @booker.senate.gov , Go!!! We need more like this from our leaders NOW.
Reposted by Teddy Yewdell
1. For the past thirty years I've had the best job in the world.
I've had the opportunity to follow my curiosity; explore the workings of nature and society; mentor students and junior colleagues in the same process; and teach generations of students about it all.
I've had the opportunity to follow my curiosity; explore the workings of nature and society; mentor students and junior colleagues in the same process; and teach generations of students about it all.
March 19, 2025 at 7:32 PM
1. For the past thirty years I've had the best job in the world.
I've had the opportunity to follow my curiosity; explore the workings of nature and society; mentor students and junior colleagues in the same process; and teach generations of students about it all.
I've had the opportunity to follow my curiosity; explore the workings of nature and society; mentor students and junior colleagues in the same process; and teach generations of students about it all.
‘If a VC firm measured efficiency purely by how little money it spent, rather than by the returns it generated, it wouldn’t last long. We invest in scientific research because we want returns — in knowledge, in lifesaving drugs, in technological capability.’
www.nytimes.com/2025/03/19/o...
www.nytimes.com/2025/03/19/o...
Opinion | DOGE Needs a Different Playbook for Science
We need less administrative bloat in science.
www.nytimes.com
March 19, 2025 at 9:20 PM
‘If a VC firm measured efficiency purely by how little money it spent, rather than by the returns it generated, it wouldn’t last long. We invest in scientific research because we want returns — in knowledge, in lifesaving drugs, in technological capability.’
www.nytimes.com/2025/03/19/o...
www.nytimes.com/2025/03/19/o...
Reposted by Teddy Yewdell
Pls read and share with family members. Thank you AAI for speaking up!!
AAI, @acpimphysicians.bsky.social, and a coalition of 34 leading scientific and medical organizations have issued a joint statement to affirm vaccine safety amid rising misinformation and declining trust.
Read the full statement: ow.ly/xtoP50VjT02.
Read the full statement: ow.ly/xtoP50VjT02.
March 19, 2025 at 2:06 PM
Pls read and share with family members. Thank you AAI for speaking up!!
Reposted by Teddy Yewdell
Well worth a read. Not because of the content - it's total horseshit - but because it's a prime example of what happens when you mix anti-science, conspiracism, arrogance, and a total lack of expertise.
Maybe one day NYT OpEds will engage with the actual science 🤷♂️.
www.nytimes.com/2025/03/16/o...
Maybe one day NYT OpEds will engage with the actual science 🤷♂️.
www.nytimes.com/2025/03/16/o...
Opinion | We Were Badly Misled About Covid (Gift Article)
The same dangerous mistakes. The same lack of candor.
www.nytimes.com
March 16, 2025 at 4:32 PM
Well worth a read. Not because of the content - it's total horseshit - but because it's a prime example of what happens when you mix anti-science, conspiracism, arrogance, and a total lack of expertise.
Maybe one day NYT OpEds will engage with the actual science 🤷♂️.
www.nytimes.com/2025/03/16/o...
Maybe one day NYT OpEds will engage with the actual science 🤷♂️.
www.nytimes.com/2025/03/16/o...
Reposted by Teddy Yewdell
