Sarah Melville
@sarahkmels.bsky.social
Reposted by Sarah Melville
1/10
Welcome to #TenPostNephJC
Last #NephJC we discussed the PISCES study 🐟 on the role of fish oil on cardiovascular events in hemodialysis patients. This study was presented at Kidney Week with simultaneous publication, and was as unexpected as a shark attack🦈.
Welcome to #TenPostNephJC
Last #NephJC we discussed the PISCES study 🐟 on the role of fish oil on cardiovascular events in hemodialysis patients. This study was presented at Kidney Week with simultaneous publication, and was as unexpected as a shark attack🦈.
December 12, 2025 at 2:59 PM
1/10
Welcome to #TenPostNephJC
Last #NephJC we discussed the PISCES study 🐟 on the role of fish oil on cardiovascular events in hemodialysis patients. This study was presented at Kidney Week with simultaneous publication, and was as unexpected as a shark attack🦈.
Welcome to #TenPostNephJC
Last #NephJC we discussed the PISCES study 🐟 on the role of fish oil on cardiovascular events in hemodialysis patients. This study was presented at Kidney Week with simultaneous publication, and was as unexpected as a shark attack🦈.
Reposted by Sarah Melville
Join us for the last #NephJC of 2025, 12/16/25 at 9pm EST!🥳
How soon should we withhold dialysis in AKI?
We're discussing the LIBERATE-D trial #NephSky
This one might just change your mind 🧠🧠
Blog by @msocomd.bsky.social and @sejalplakhani.bsky.social
www.nephjc.com/news/liberated-aki
How soon should we withhold dialysis in AKI?
We're discussing the LIBERATE-D trial #NephSky
This one might just change your mind 🧠🧠
Blog by @msocomd.bsky.social and @sejalplakhani.bsky.social
www.nephjc.com/news/liberated-aki
Dialyze Less, Recover More? AKI’s Chance to Get LIBERATE-D — NephJC
This week, we will discuss whether less is more when it comes to discontinuing dialysis in patients with AKI and a chance to recover.
www.nephjc.com
December 15, 2025 at 2:41 PM
Join us for the last #NephJC of 2025, 12/16/25 at 9pm EST!🥳
How soon should we withhold dialysis in AKI?
We're discussing the LIBERATE-D trial #NephSky
This one might just change your mind 🧠🧠
Blog by @msocomd.bsky.social and @sejalplakhani.bsky.social
www.nephjc.com/news/liberated-aki
How soon should we withhold dialysis in AKI?
We're discussing the LIBERATE-D trial #NephSky
This one might just change your mind 🧠🧠
Blog by @msocomd.bsky.social and @sejalplakhani.bsky.social
www.nephjc.com/news/liberated-aki
Reposted by Sarah Melville
Nice paper Ben but it's hard to justify use of AUROC except when there is only one candidate model. AUROC should not be used to judge improvements in predictive discrimination. The width of a well-calibrated risk distribution is far better for that. #StatsSky #Statistics fharrell.com/post/addvalue
Statistically Efficient Ways to Quantify Added Predictive Value of New Measurements – Statistical Thinking
Researchers have used contorted, inefficient, and arbitrary analyses to demonstrated added value in biomarkers, genes, and new lab measurements. Traditional statistical measures have always been up to...
fharrell.com
December 13, 2025 at 3:18 PM
Nice paper Ben but it's hard to justify use of AUROC except when there is only one candidate model. AUROC should not be used to judge improvements in predictive discrimination. The width of a well-calibrated risk distribution is far better for that. #StatsSky #Statistics fharrell.com/post/addvalue
Reposted by Sarah Melville
I don't get the rise of the medical paternalism. Remember one of the cardinal rules in the House of God , "The patient is the one with the disease"?
If the patient does not want to take the advice offered, so be it: #UDoU, #FAFO, caveat emptor are parts of adult life & death.
If the patient does not want to take the advice offered, so be it: #UDoU, #FAFO, caveat emptor are parts of adult life & death.
December 11, 2025 at 10:58 AM
Reposted by Sarah Melville
Primary Aldosteronism: The 2025 Endocrine Society CPG Webinar | Join Gail K. Adler, MD, PhD, and @ricardocorreamd.bsky.social, on Friday, December 12 at 12:00 PM ET for a discussion of the updates from the previous 2016 guidelines and assessment of future challenges: bit.ly/3NpIQdB #endocrinology
December 10, 2025 at 5:41 PM
Primary Aldosteronism: The 2025 Endocrine Society CPG Webinar | Join Gail K. Adler, MD, PhD, and @ricardocorreamd.bsky.social, on Friday, December 12 at 12:00 PM ET for a discussion of the updates from the previous 2016 guidelines and assessment of future challenges: bit.ly/3NpIQdB #endocrinology
Reposted by Sarah Melville
GLP1RAs and peri operative risks
www.bjanaesthesia.org/article/S000...
And
jamanetwork.com/journals/jam...
Does the GLP1RA #anesthesia risk need reevaluation? Or an RCT? Or are anecdotal case reports enough? @glbryson.bsky.social
www.bjanaesthesia.org/article/S000...
And
jamanetwork.com/journals/jam...
Does the GLP1RA #anesthesia risk need reevaluation? Or an RCT? Or are anecdotal case reports enough? @glbryson.bsky.social
Risk of perioperative cardiorespiratory complications and mortality associated with preoperative glucagon-like peptide-1 receptor agonist use in type 2 diabetes mellitus: a nationwide propensity-score...
The use of glucagon-like peptide-1 receptor agonists (GLP-1 RAs) has raised concerns
about delayed gastric emptying, pulmonary aspiration, and respiratory complications.
This study aimed to investigat...
www.bjanaesthesia.org
December 9, 2025 at 11:23 PM
GLP1RAs and peri operative risks
www.bjanaesthesia.org/article/S000...
And
jamanetwork.com/journals/jam...
Does the GLP1RA #anesthesia risk need reevaluation? Or an RCT? Or are anecdotal case reports enough? @glbryson.bsky.social
www.bjanaesthesia.org/article/S000...
And
jamanetwork.com/journals/jam...
Does the GLP1RA #anesthesia risk need reevaluation? Or an RCT? Or are anecdotal case reports enough? @glbryson.bsky.social
Reposted by Sarah Melville
Excellent Rare Kidney Disease Conference hosted by Loma Linda at the historic Mission Inn led by @saynanorouzi.bsky.social great case discussions on IgA nephropathy, c3G, PKd, genetic testing and galore! Enjoyed the AI discussant as an additional panelist, and Dr Glassock taking down AI bots
December 7, 2025 at 10:11 PM
Excellent Rare Kidney Disease Conference hosted by Loma Linda at the historic Mission Inn led by @saynanorouzi.bsky.social great case discussions on IgA nephropathy, c3G, PKd, genetic testing and galore! Enjoyed the AI discussant as an additional panelist, and Dr Glassock taking down AI bots
lol, soo funny!, 😃😂
“Meat Free Monday” 👀😳😱😂😂
“Alternatives terms for plant-based (fake)-meat products include ‘discs’ or ‘tubes’”… or ‘cardboard.’ 😃😂😂
cc: @christosargyrop.bsky.social 😃😂
“Meat Free Monday” 👀😳😱😂😂
“Alternatives terms for plant-based (fake)-meat products include ‘discs’ or ‘tubes’”… or ‘cardboard.’ 😃😂😂
cc: @christosargyrop.bsky.social 😃😂
Yep. A vegeburger is a burger. A vegesausage is a sausage. Nobody’s confused. Let it be.
www.theguardian.com/business/202...
www.theguardian.com/business/202...
Let it be: Paul McCartney urges EU to drop ban on veggie ‘burgers’ and ‘sausages’
Former Beatle argues use of terms for meat-free products ‘encourages attitudes essential to our health’
www.theguardian.com
December 7, 2025 at 5:46 PM
lol, soo funny!, 😃😂
“Meat Free Monday” 👀😳😱😂😂
“Alternatives terms for plant-based (fake)-meat products include ‘discs’ or ‘tubes’”… or ‘cardboard.’ 😃😂😂
cc: @christosargyrop.bsky.social 😃😂
“Meat Free Monday” 👀😳😱😂😂
“Alternatives terms for plant-based (fake)-meat products include ‘discs’ or ‘tubes’”… or ‘cardboard.’ 😃😂😂
cc: @christosargyrop.bsky.social 😃😂
Reposted by Sarah Melville
#Diabetes-related #foot #ulcers (DFUs) continue to inflict a harmful toll on people with diabetes due to the medical treatments & lifestyle changes needed to heal these lesions or, in the case of healing failure, limb loss through amputation thelancet.com/journals/lan...
#T1D #T2D
#MedSky #EndoSky
#T1D #T2D
#MedSky #EndoSky
December 7, 2025 at 5:31 PM
#Diabetes-related #foot #ulcers (DFUs) continue to inflict a harmful toll on people with diabetes due to the medical treatments & lifestyle changes needed to heal these lesions or, in the case of healing failure, limb loss through amputation thelancet.com/journals/lan...
#T1D #T2D
#MedSky #EndoSky
#T1D #T2D
#MedSky #EndoSky
Reposted by Sarah Melville
⏰2 hours until #NephJC chat
Does the use of fish oil is pious elixir in hemodialysis patients, protecting the heart like Lord Vishnu protecting the Vedas from the Asuras in the Matsya avatar?
Join us for the NephJC chat at 9 PM EST to learn more about the recently published PISCES study.
Does the use of fish oil is pious elixir in hemodialysis patients, protecting the heart like Lord Vishnu protecting the Vedas from the Asuras in the Matsya avatar?
Join us for the NephJC chat at 9 PM EST to learn more about the recently published PISCES study.
December 3, 2025 at 12:00 AM
⏰2 hours until #NephJC chat
Does the use of fish oil is pious elixir in hemodialysis patients, protecting the heart like Lord Vishnu protecting the Vedas from the Asuras in the Matsya avatar?
Join us for the NephJC chat at 9 PM EST to learn more about the recently published PISCES study.
Does the use of fish oil is pious elixir in hemodialysis patients, protecting the heart like Lord Vishnu protecting the Vedas from the Asuras in the Matsya avatar?
Join us for the NephJC chat at 9 PM EST to learn more about the recently published PISCES study.
Reposted by Sarah Melville
Holy Mackerel! 🐟
🦜Ahoy matey! Could fish oil unlock the mysteries of increased CV mortality in ESRD? 🏴☠️ #NephJC
Join us for a lively trawling trip 12/2/25 🛥️at 9pm EST
Check out the PISCES VA by @brianrifkin.bsky.social
www.nephjc.com/news/piscesva
🦜Ahoy matey! Could fish oil unlock the mysteries of increased CV mortality in ESRD? 🏴☠️ #NephJC
Join us for a lively trawling trip 12/2/25 🛥️at 9pm EST
Check out the PISCES VA by @brianrifkin.bsky.social
www.nephjc.com/news/piscesva
PISCES: The Visual Abstract — NephJC
Curious how n-3 PUFAs may cut serious cardiovascular events in dialysis? 🐟 A big signal, a big dose, and a big discussion ahead — don’t miss this #NephJC! Check out the VA made by our master Brian...
www.nephjc.com
December 1, 2025 at 6:47 PM
Holy Mackerel! 🐟
🦜Ahoy matey! Could fish oil unlock the mysteries of increased CV mortality in ESRD? 🏴☠️ #NephJC
Join us for a lively trawling trip 12/2/25 🛥️at 9pm EST
Check out the PISCES VA by @brianrifkin.bsky.social
www.nephjc.com/news/piscesva
🦜Ahoy matey! Could fish oil unlock the mysteries of increased CV mortality in ESRD? 🏴☠️ #NephJC
Join us for a lively trawling trip 12/2/25 🛥️at 9pm EST
Check out the PISCES VA by @brianrifkin.bsky.social
www.nephjc.com/news/piscesva
Reposted by Sarah Melville
Maybe the most shocking study from #KidneyWk.
🐚From the depths of the oceans to #BlueSky, we're discussing PISCES 🐟 12/2/25 9pm EST. #NephJC
Are you hooked🪝on fish oil for CV disease in ESRD, or are you throwing it back 🌊?
www.nephjc.com/news/pisces-fishoil
🐚From the depths of the oceans to #BlueSky, we're discussing PISCES 🐟 12/2/25 9pm EST. #NephJC
Are you hooked🪝on fish oil for CV disease in ESRD, or are you throwing it back 🌊?
www.nephjc.com/news/pisces-fishoil
Fish Oil in Dialysis: A Big Catch or an Empty Net — NephJC
Holy Mackerel! This week we will discuss fish oil use in maintenance hemodialysis patients. Could this be the one thing that bends the curve on CV mortality, or is it just a red herring?
www.nephjc.com
December 1, 2025 at 6:41 PM
Maybe the most shocking study from #KidneyWk.
🐚From the depths of the oceans to #BlueSky, we're discussing PISCES 🐟 12/2/25 9pm EST. #NephJC
Are you hooked🪝on fish oil for CV disease in ESRD, or are you throwing it back 🌊?
www.nephjc.com/news/pisces-fishoil
🐚From the depths of the oceans to #BlueSky, we're discussing PISCES 🐟 12/2/25 9pm EST. #NephJC
Are you hooked🪝on fish oil for CV disease in ESRD, or are you throwing it back 🌊?
www.nephjc.com/news/pisces-fishoil
Reposted by Sarah Melville
A result this shiny usually means you check for scales! 🎣
Do read and enjoy our #NephJC summary/critical appraisal of the 🐟PISCES 🐟 Study (Fish Oil in Dialysis)
www.nephjc.com/news/pisces-...
@nephjc.bsky.social
Do read and enjoy our #NephJC summary/critical appraisal of the 🐟PISCES 🐟 Study (Fish Oil in Dialysis)
www.nephjc.com/news/pisces-...
@nephjc.bsky.social
December 1, 2025 at 7:25 PM
A result this shiny usually means you check for scales! 🎣
Do read and enjoy our #NephJC summary/critical appraisal of the 🐟PISCES 🐟 Study (Fish Oil in Dialysis)
www.nephjc.com/news/pisces-...
@nephjc.bsky.social
Do read and enjoy our #NephJC summary/critical appraisal of the 🐟PISCES 🐟 Study (Fish Oil in Dialysis)
www.nephjc.com/news/pisces-...
@nephjc.bsky.social
Reposted by Sarah Melville
When someone knows two or more languages, all those languages remain active in the brain. The brain must select the right language while keeping others from interfering. This constant mental exercise acts a bit like daily "brain training". #RSNA25
www.sciencealert.com/speaking-mul...
www.sciencealert.com/speaking-mul...
Speaking Multiple Languages May Slow Brain Aging, Study Suggests
People are living longer than ever around the world.
www.sciencealert.com
December 1, 2025 at 3:47 AM
When someone knows two or more languages, all those languages remain active in the brain. The brain must select the right language while keeping others from interfering. This constant mental exercise acts a bit like daily "brain training". #RSNA25
www.sciencealert.com/speaking-mul...
www.sciencealert.com/speaking-mul...
Reposted by Sarah Melville
Tomorrow: The Future of Medicine is here!
Episode 1 drops Dec. 1, featuring Will Flanary — better known as @glaucomflecken.bsky.social.
Subscribe anywhere you listen to podcasts or watch on YouTube at https://bit.ly/44vtyMX.
#FutureOfMedicine #StanDOM
Episode 1 drops Dec. 1, featuring Will Flanary — better known as @glaucomflecken.bsky.social.
Subscribe anywhere you listen to podcasts or watch on YouTube at https://bit.ly/44vtyMX.
#FutureOfMedicine #StanDOM
November 30, 2025 at 6:41 PM
Tomorrow: The Future of Medicine is here!
Episode 1 drops Dec. 1, featuring Will Flanary — better known as @glaucomflecken.bsky.social.
Subscribe anywhere you listen to podcasts or watch on YouTube at https://bit.ly/44vtyMX.
#FutureOfMedicine #StanDOM
Episode 1 drops Dec. 1, featuring Will Flanary — better known as @glaucomflecken.bsky.social.
Subscribe anywhere you listen to podcasts or watch on YouTube at https://bit.ly/44vtyMX.
#FutureOfMedicine #StanDOM
Reposted by Sarah Melville
I'd like to propose a moratorium on DAPT research in the post-ACS population. I have no idea what there is left to learn. There are known trade-offs and a nice calculator.
November 30, 2025 at 12:10 PM
I'd like to propose a moratorium on DAPT research in the post-ACS population. I have no idea what there is left to learn. There are known trade-offs and a nice calculator.
Reposted by Sarah Melville
Join the Filtrate and Jon Barratt as he takes an IgAN inspired victory lap
FF 86 Atacicept for IgAN
www.nephjc.com/freelyfilter...
FF 86 Atacicept for IgAN
www.nephjc.com/freelyfilter...
FF 86 Atacicept for IgAN with Jon Barratt — NephJC
FF 86 Atacicept for IgAN with Jon Barratt
www.nephjc.com
November 28, 2025 at 3:01 PM
Join the Filtrate and Jon Barratt as he takes an IgAN inspired victory lap
FF 86 Atacicept for IgAN
www.nephjc.com/freelyfilter...
FF 86 Atacicept for IgAN
www.nephjc.com/freelyfilter...
Reposted by Sarah Melville
Skin Disorders in Kidney Disease: Core Curriculum 2026 - American Journal of Kidney Diseases ajkd.org/article/S027... Thankful for the opportunity to contribute to this Core Curriculum feature.
🙏
🙏
Skin Disorders in Kidney Disease: Core Curriculum 2026
Skin disorders occur commonly in patients with chronic kidney disease (CKD) and may
greatly impact their quality of life. These skin disorders have varying underlying
pathophysiologies, but there are ...
ajkd.org
November 28, 2025 at 1:30 AM
Skin Disorders in Kidney Disease: Core Curriculum 2026 - American Journal of Kidney Diseases ajkd.org/article/S027... Thankful for the opportunity to contribute to this Core Curriculum feature.
🙏
🙏
November 28, 2025 at 1:02 AM
Reposted by Sarah Melville
November 27, 2025 at 5:00 PM
Reposted by Sarah Melville
Advance care planning: we need to change our approach to improve patient and clinician engagement - Kidney International Reports www.kireports.org/article/S246...
Advance care planning: we need to change our approach to improve patient and clinician engagement
Advance care planning (ACP) is the process of evaluating and defining goals and preferences
for future medical treatment and care. ACP enables these discussions with care partners
and health care prof...
www.kireports.org
November 27, 2025 at 4:52 PM
Advance care planning: we need to change our approach to improve patient and clinician engagement - Kidney International Reports www.kireports.org/article/S246...
Reposted by Sarah Melville
That was quick!
The US FDA approves Sibeprenlimab aka Voyxact for reducing proteinuria in IgA
www.fda.gov/drugs/novel-...
#NephSky
#TopNephrology
The US FDA approves Sibeprenlimab aka Voyxact for reducing proteinuria in IgA
www.fda.gov/drugs/novel-...
#NephSky
#TopNephrology
November 26, 2025 at 12:21 AM
That was quick!
The US FDA approves Sibeprenlimab aka Voyxact for reducing proteinuria in IgA
www.fda.gov/drugs/novel-...
#NephSky
#TopNephrology
The US FDA approves Sibeprenlimab aka Voyxact for reducing proteinuria in IgA
www.fda.gov/drugs/novel-...
#NephSky
#TopNephrology
Reposted by Sarah Melville
It’s absolutely absurd that American doctors haven’t completely turned on the AMA and this administration.
But not so absurd when you realize German doctors did the exact same thing in 1933. Bad, horrible things incoming.
But not so absurd when you realize German doctors did the exact same thing in 1933. Bad, horrible things incoming.
pmc.ncbi.nlm.nih.gov
November 26, 2025 at 1:22 AM
It’s absolutely absurd that American doctors haven’t completely turned on the AMA and this administration.
But not so absurd when you realize German doctors did the exact same thing in 1933. Bad, horrible things incoming.
But not so absurd when you realize German doctors did the exact same thing in 1933. Bad, horrible things incoming.
Reposted by Sarah Melville
Well deserved Cristina and Brian!
Don't think we won't hound u @hswapnil.medsky.social @kidneyboy.bsky.social ! 😉
Don't think we won't hound u @hswapnil.medsky.social @kidneyboy.bsky.social ! 😉
November 25, 2025 at 12:09 PM
Well deserved Cristina and Brian!
Don't think we won't hound u @hswapnil.medsky.social @kidneyboy.bsky.social ! 😉
Don't think we won't hound u @hswapnil.medsky.social @kidneyboy.bsky.social ! 😉
Reposted by Sarah Melville
What an incredible commitment it’s been, ten years and a whole ecosystem of learning and innovation. Thank you both for your leadership and also that you’ve made sure NephJC will continue to grow in the future.
November 25, 2025 at 12:56 PM
What an incredible commitment it’s been, ten years and a whole ecosystem of learning and innovation. Thank you both for your leadership and also that you’ve made sure NephJC will continue to grow in the future.