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The Lancet Diabetes & Endocrinology
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Your leading source of international, cutting-edge research, review, and opinion in clinical #diabetes and #endocrinology. IF=41·8.

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The Lancet is a weekly peer-reviewed general medical journal, founded in England in 1823. It is one of the world's highest-impact academic journals and also one of the oldest medical journals still in publication. .. more

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The Lancet Diabetes & Endocrinology @thelancetendo.bsky.social · 16d
Read our December Issue, featuring familial hypercholesterolaemia, chronic kidney disease, type 2 diabetes, cyclic Cushing’s syndrome, primary aldosteronism, type 1 diabetes, menopause, obesity, iodine deficiency, & much more tinyurl.com/mwfu4c6m

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The Lancet Diabetes & Endocrinology @thelancetendo.bsky.social · 3h
Estimates suggest that 1–10% of the general population currently harbours an #adrenal #tumour, peaking in prevalence in the seventh and eighth decades of life www.thelancet.com/journals/lan...

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Reposted by The Lancet Diabetes Endocrinology

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The Lancet @thelancet.com · 19h
One in five of the population lives with chronic pain.

In a Review, authors discuss core principles for psychological pain management and practical advice for how to facilitate pain self-management in clinical practice: spkl.io/63323Ae4Nl
Figure showing psychological interventions for chronic pain and alterations in neurobiological underpinnings. Copyright: 2025 Elsevier Ltd. All rights are reserved.

Reposted by The Lancet Diabetes Endocrinology

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The Lancet @thelancet.com · 1d
Present a talk or poster alongside a stellar faculty at The #LancetSummit: shaping the future of #diabetes prevention. Abstract submission is open until Jun 12, 2026. View our Advisory Board and learn how you can take part: hubs.li/Q03MV20T0
The Lancet Summit: shaping the future of diabetes prevention. Image credit: Ixefra / Getty Images.

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The Lancet Diabetes & Endocrinology @thelancetendo.bsky.social · 1d
New Editorial:
Diabetes and cancer in the age of multimorbidity thelancet.com/journals/lan...
#diabetes #cancer #multimorbidity
#FREE to read
#LGCW2025 #LondonGlobalCancerWeek
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Diabetes and cancer in the age of multimorbidity
Diabetes and cancer are two of the four major non-communicable diseases identified by WHO. Their relationship is multifaceted and complex, involving shared biological mechanisms and overlapping risk f...
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The Lancet Diabetes & Endocrinology @thelancetendo.bsky.social · 1d
Published in The Lancet Digital Health:

Automated retinal image analysis systems to triage for grading of #diabetic #retinopathy: a large-scale, open-label, national screening programme in England www.thelancet.com/journals/lan...
#OpenAccess

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Automated retinal image analysis systems to triage for grading of diabetic retinopathy: a large-scale, open-label, national screening programme in England
ARIAS showed high sensitivity for medium-risk and high-risk diabetic retinopathy in a real-world screening service, with equitable performance across population subgroups. ARIAS could provide a cost-e...
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The Lancet Diabetes & Endocrinology @thelancetendo.bsky.social · 2d
Until glycaemic targets for #CGM use in #gestational #diabetes are better defined, rt-CGM could be considered for selected patients under the supervision of an experienced care team www.thelancet.com/journals/lan... #GDM

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The Lancet Diabetes & Endocrinology @thelancetendo.bsky.social · 2d
In four of seven jurisdictions with #heartfailure data available, declines in heart failure mortality were less marked than declines in mortality due to #atherosclerotic #cardiovascular disease in people with & without #diabetes www.thelancet.com/journals/lan... #ASCVD

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Time trends in mortality from heart failure and atherosclerotic cardiovascular disease in people with and without diabetes: a multi-national population-based study
Declines in heart failure mortality in both people with and without diabetes were less marked than were declines in CHD and cerebrovascular disease mortality in most jurisdictions. Heart failure morta...
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Reposted by The Lancet Diabetes Endocrinology

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The Lancet @thelancet.com · 3d
Want to stay up to date with the latest original research, perspectives and insights in your field? 🏥

Explore our Specialty Collections to stay informed with the most current and relevant content published across The Lancet Group.

🔗 spkl.io/63329AedK5
A blue square with the words, "Clinical Resources" and a take on the Rod of Asclepius; a traditional symbol of medicine.

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The Lancet Diabetes & Endocrinology @thelancetendo.bsky.social · 3d
Linked Comment by Lene Ringholm:
Does continuous glucose monitoring deliver in #gestational #diabetes? thelancet.com/journals/lan...
#CGM

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Does continuous glucose monitoring deliver in gestational diabetes?
Women with gestational diabetes continue to have adverse pregnancy outcomes that are often related to hyperglycaemia. Maternal glucose is the major determinant of increased birthweight and there are s...
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The Lancet Diabetes & Endocrinology @thelancetendo.bsky.social · 3d
New—Glycaemic control and pregnancy outcomes with real-time continuous glucose monitoring in #gestational #diabetes (GRACE): an open-label, multicentre, multinational, randomised controlled trial thelancet.com/journals/lan...
#CGM

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Glycaemic control and pregnancy outcomes with real-time continuous glucose monitoring in gestational diabetes (GRACE): an open-label, multicentre, multinational, randomised controlled trial
rt-CGM use in women with gestational diabetes reduced LGA births, without differences in serious adverse events. The higher-than-expected overall prevalence of SGA infants, possibly related to the tig...
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The Lancet Diabetes & Endocrinology @thelancetendo.bsky.social · 4d
Linked Comment by Michael Roden:
The long and winding road to precision diabetology www.thelancet.com/journals/lan...
#diabetes #PrecisionMedicine

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The long and winding road to precision diabetology
There is increasing interest in delineating the heterogeneity of diabetes to develop precision diabetology.1 In 2018, Ahlqvist and colleagues2 introduced unbiased phenotype-based clustering to subtype...
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The Lancet Diabetes & Endocrinology @thelancetendo.bsky.social · 4d
#Comorbidities and #mortality in #subgroups of adults with #diabetes with up to 14 years follow-up: a prospective cohort study in Sweden www.thelancet.com/journals/lan...
#PrecisionMedicine

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Comorbidities and mortality in subgroups of adults with diabetes with up to 14 years follow-up: a prospective cohort study in Sweden
Diabetes subgroups could inform on outcomes, as well as guide treatment and follow-up needed for newly diagnosed individuals with diabetes. SIRD stands out as a high-risk subgroup that is not identifi...
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Reposted by The Lancet Diabetes Endocrinology

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The Lancet @thelancet.com · 5d
Non-coeliac gluten sensitivity (NCGS) remains a highly debated condition, despite ~10% of the global population self-reporting a gluten or wheat sensitivity.

A Review examines current evidence & provides practical guidance for assessment and management: spkl.io/63328AdQha
Symptoms and onset times for non-coeliac gluten sensitivity. Copyright: Elsevier Ltd. All rights are reserved, including those for text and data mining, AI training, and similar technologies.

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The Lancet Diabetes & Endocrinology @thelancetendo.bsky.social · 6d
Multiple endocrine neoplasia type 1 (MEN1): recommendations and guidelines for best practice thelancet.com/journals/lan... #MEN1
#FREE to read with registration (also FREE)

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Multiple endocrine neoplasia type 1 (MEN1): recommendations and guidelines for best practice
Multiple endocrine neoplasia type 1 (MEN1) is characterised by combined occurrence of parathyroid tumours, duodenopancreatic neuroendocrine tumours, and anterior pituitary adenomas. Some patients migh...
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Reposted by The Lancet Diabetes Endocrinology

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The Lancet @thelancet.com · 6d
Peripartum cardiomyopathy is now the leading cause of maternal death in many parts of the world.

A Seminar summarises current knowledge of peripartum cardiomyopathy genetics, pathophysiology, diagnostic approaches, medical management, and outcome: spkl.io/63320AdQNn
Figure showing risk factors and pathological mechanisms linked to peripartum cardiomyopathy. Copyright: 2025 Elsevier Ltd. All rights are reserved.

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The Lancet Diabetes & Endocrinology @thelancetendo.bsky.social · 6d
Adrenal tumour imaging: clinical, molecular, and radiomics perspectives thelancet.com/journals/lan...
#adrenal #tumour

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The Lancet Diabetes & Endocrinology @thelancetendo.bsky.social · 6d
New—In Focus with Talha Burki:
Getting smart about the food we eat thelancet.com/journals/lan...
ultra-processed foods #UPFs #obesity
#FREE to read with registration (also FREE)

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Getting smart about the food we eat
In April 2025, Kevin Hall took early retirement from the US National Institutes of Health (NIH). “My life's work has been to scientifically study how our food environment affects what we eat, and how ...
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Reposted by The Lancet Diabetes Endocrinology

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The Lancet @thelancet.com · 6d
788 million people worldwide were living with chronic kidney disease in 2023. Yet neither awareness nor action match the threat posed to health.

Our latest Editorial ➡️ "Chronic kidney disease: breaking the silence" spkl.io/63324AdQLO
A quote from The Lancet's Nov 22, 2025 Editorial. Quote reads: "Detecting and treating [Chronic Kidney Disease] provides an opportunity to stem the tide of multiple adverse health outcomes, with huge potential economic benefits. It is an opportunity that must be taken."

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The Lancet Diabetes & Endocrinology @thelancetendo.bsky.social · 7d
"We present 25 questions on the most important aspects of the clinical management of adult patients with #adrenocortical #carcinoma that we have frequently asked ourselves over the past 25 years" www.thelancet.com/journals/lan...
#OpenAccess

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Adrenocortical carcinoma: a practical guide for clinicians
Adrenocortical carcinoma is a rare endocrine malignancy. The management of patients with adrenocortical carcinoma is challenging for several reasons, including its heterogeneous but frequently aggress...
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The Lancet Diabetes & Endocrinology @thelancetendo.bsky.social · 7d
The effect of #overdiagnosis has been so pronounced that it has changed the global epidemiological landscape of #thyroid #cancer among adolescents and young adults (AYAs), mirroring patterns in older adults www.thelancet.com/journals/lan...
#thyroidcancer

#MedSky #EndoSky #OncSky

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The Lancet Diabetes & Endocrinology @thelancetendo.bsky.social · 7d
Portion sizes and caloric inequity: a hidden driver of obesity disparities www.thelancet.com/journals/lan...
#obesity
#FREE to read

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The Lancet Diabetes & Endocrinology @thelancetendo.bsky.social · 8d
The application of implementation science to expanding knowledge of #familial #hypercholesterolaemia has enabled the development and design of potentially more effective models of care www.thelancet.com/journals/lan...
#ASCVD #cholesterol

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The Lancet Diabetes & Endocrinology @thelancetendo.bsky.social · 8d
Jonathan Pearson-Stuttard & Julia A Critchley comment on:
Heterogeneity in type 2 #diabetes trajectories: informing public health approaches www.thelancet.com/journals/lan... #T2D #cancer
#FREE to read with registration (also FREE)

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Heterogeneity in type 2 diabetes trajectories: informing public health approaches
In The Lancet Diabetes & Endocrinology, Francesco Zaccardi and colleagues1 provide a thoughtful analysis of transitions to type 2 diabetes and cancer development and mortality among 330 000 people liv...
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The Lancet Diabetes & Endocrinology @thelancetendo.bsky.social · 8d
New—Trajectories of type 2 #diabetes and #cancer in 330 000 individuals with prediabetes: 20-year observational study in England www.thelancet.com/journals/lan... #T2D
#OpenAccess

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Trajectories of type 2 diabetes and cancer in 330 000 individuals with prediabetes: 20-year observational study in England
The trajectories of type 2 diabetes and cancer following a diagnosis of prediabetes varied substantially by age at prediabetes diagnosis and, to a lesser extent, other sociodemographic and lifestyle f...
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The Lancet Diabetes & Endocrinology @thelancetendo.bsky.social · 8d
Tommaso Porcellia & Martin Schlumberger comment on:
The rise of thyroid cancer incidence in adolescents and young adults thelancet.com/journals/lan...
#thyroid #cancer

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The rise of thyroid cancer incidence in adolescents and young adults
In The Lancet Diabetes & Endocrinology, Mengmeng Li and colleagues analysed global trends in thyroid cancer incidence from 2003 to 2017 and contemporary burden for the year 2022 among adolescents and ...
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The Lancet Diabetes & Endocrinology @thelancetendo.bsky.social · 8d
New—Thyroid cancer in adolescents and young adults: a population-based study in 185 countries worldwide thelancet.com/journals/lan...
#thyroid #cancer

#MedSky #EndoSky #OncSky

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The Lancet Diabetes & Endocrinology @thelancetendo.bsky.social · 8d
Linked Comment:
Empagliflozin in chronic kidney disease: evidence for early, inclusive, and confident use www.thelancet.com/journals/lan...
#CKD

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Empagliflozin in chronic kidney disease: evidence for early, inclusive, and confident use
The scenario of chronic kidney disease (CKD) management has been transformed by the advent of sodium glucose co-transporter-2 (SGLT2) inhibitors, a class of drugs with benefits extending well beyond g...
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The Lancet Diabetes & Endocrinology @thelancetendo.bsky.social · 8d
#SGLT2 inhibition reduces risk of acute and chronic #kidney outcomes irrespective of the size of the acute dip in eGFR. Kidney benefits are evident irrespective of diabetes status, heart failure status, primary cause of kidney disease, and markers of severity of these diseases tinyurl.com/m9jmk592.
Effects of empagliflozin on conventional and exploratory acute and chronic kidney outcomes: an individual participant-level meta-analysis
SGLT2 inhibition reduces risk of acute and chronic kidney outcomes irrespective of the size of the acute dip in eGFR. Kidney benefits are evident irrespective of diabetes status, heart failure status,...
tinyurl.com

Reposted by Christopher Millett, Phillip Baker, The Lancet Diabetes Endocrinology , and 2 more

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The Lancet @thelancet.com · 8d
Ultra-processed foods – what’s the impact?

In a new Lancet Series, experts warn a global rise in #UPFs presents a growing public health threat.

Read the evidence & policy recommendations ⬇️
spkl.io/63327AduhR
Part of a Lancet Infographic summarising the findings from the Lancet Series on Ultra-Processed Foods and Human Health. Part of a Lancet Infographic summarising the findings from the Lancet Series on Ultra-Processed Foods and Human Health. Part of a Lancet Infographic summarising the findings from the Lancet Series on Ultra-Processed Foods and Human Health.

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The Lancet Diabetes & Endocrinology @thelancetendo.bsky.social · 8d
#Adrenal tumours have become a common incidental finding in the radiological evaluation of patients. Estimates suggest that 1–10% of the general population currently harbours an adrenal tumour, peaking in prevalence in the seventh and eighth decades of life thelancet.com/journals/lan...

#EndoSky