banner
LightNews
neuroniv.bsky.social
Nivedita Sarveswaran
@neuroniv.bsky.social
500 followers 360 following 160 posts
Postdoc in pain genetics & nociceptor biology @TheCIMR | via @biokent @UCLQSIoN @YaleMed | 🇦🇺🇬🇧🇱🇰
Posts Media Videos Starter Packs
Pinned
neuroniv.bsky.social
Nivedita Sarveswaran @neuroniv.bsky.social · Jan 30
Lots of writing on the cards over the next few months but thoroughly enjoying all the advice and memes I have saved from PhD thesis time. Might start a thread, but for now, keeping this one front and centre
Tweet by @AlexAndBooks_ “If you’re overthinking, write. If you’re underthinking, read.”
1 1 11
Reposted by Nivedita Sarveswaran
kristalerista.bsky.social
Krista Koeller @kristalerista.bsky.social · 21h
Dear funding agencies,

I know we all want to discover the wonder drug that will cure the horrible diseases, but to do that, we need to invest in basic, unsexy, foundational research on how the systems work. Funding can’t all be drug development.

Sincerely,
Looking for basic research grants.
42 360 2.1K
Reposted by Nivedita Sarveswaran
gershbrain.bsky.social
Sam Gershman @gershbrain.bsky.social · 7h
When I was an undergrad, I saw a talk by Oliver Sacks about music. During the Q&A, someone asked Sacks if he thought science would reveal the deepest mysteries of art. Sacks (a rare humanist among scientists) said that he doubted it, at which Eric Kandel (the host) leaped up and grabbed the mic.
14 19 130
Reposted by Nivedita Sarveswaran
jphysiol.bsky.social
The Journal of Physiology @jphysiol.bsky.social · 1d
Recent #Research by Yucheng Xiao et al. observed that contusive spinal cord injury causes Nav1.8 dysfunction to upregulate small sensory #neuron excitability 🧠 ⚡

📜 Read the article here: physoc.onlinelibrary.wiley.com/doi/10.1113/...
2 1
Reposted by Nivedita Sarveswaran
psalmotoxin.bsky.social
Ewan St. John Smith @psalmotoxin.bsky.social · 1d
If evolution, comparative #neuroskyence & #PainResearch are your thing, here's a great review from Terry Walters: journals.biologists.com/jeb/article/...
From nociception in aneural animals to human suffering: toward a comparative biology of pain
Summary: The biology of widely shared and unusual features of human pain is informed by functional and mechanistic comparisons of nociception and pain-like aversive states across vertebrate and invert...
journals.biologists.com
13 33
neuroniv.bsky.social
Nivedita Sarveswaran @neuroniv.bsky.social · 2d
Also Prof. Maria Fitzgerald is a leader in understanding pain in neonates, including how CNS wiring of ‘pain circuits’ develop and mature pubmed.ncbi.nlm.nih.gov/26446174/
What do we really know about newborn infant pain? - PubMed
What is the topic of this review? Pain in infancy. What advances does it highlight? New neurophysiological research on pain processing in the human infant brain. Increased awareness of pain in the new...
pubmed.ncbi.nlm.nih.gov
2
neuroniv.bsky.social
Nivedita Sarveswaran @neuroniv.bsky.social · 2d
Ah got it, the how is a fascinating question! Sidebar: I found the Bernard/Arnold storyline in the first couple of seasons of Westworld to touch on this in a pretty evocative way.
1 1
neuroniv.bsky.social
Nivedita Sarveswaran @neuroniv.bsky.social · 2d
Do you mean that it seems cruel for them to learn that it hurts so early when they can’t do anything about it yet? Because for patients with congenital insensitivity to pain, the consequences arise as early as in the first year and can lead to long-term complications on physical and mental health.
1 1
Reposted by Nivedita Sarveswaran
rightnowoneils.bsky.social
Elena 🎃 @rightnowoneils.bsky.social · 9d
Olivia dean is so fall coded wow I love this woman 🫰🫰 snaps for my girl
a woman with curly hair is wearing a white dress and earrings and smiling with her eyes closed .
ALT: a woman with curly hair is wearing a white dress and earrings and smiling with her eyes closed .
media.tenor.com
3 1 17
Reposted by Nivedita Sarveswaran
royalsociety.org
The Royal Society @royalsociety.org · 5d
There's still time to apply for our Dorothy Hodgkin Fellowships. This scheme offers a first step into an independent research career for outstanding early career scientists who require flexible working circumstances.

#RSGrants

https://bit.ly/4h1hzf3
1 4 3
Reposted by Nivedita Sarveswaran
jgp.org
Journal of General Physiology @jgp.org · 5d
This Special Issue rupress.org/jgp/search-r... brings together a collection of studies that exemplify the multidimensional progress in physiology, pharmacology, & structure-function analysis of voltage-gated sodium channels. Editorial by Abriel & @lampertlab.bsky.social: rupress.org/jgp/article/...
6 7
Reposted by Nivedita Sarveswaran
aubinmoutal.bsky.social
Aubin Moutal @aubinmoutal.bsky.social · 6d
So excited to share our preprint uncovering FGFR3 autoantibodies as pathogenic drivers of pain sensitization.
Using patient serum, human DRG and rat models, we found that autoantibodies can find FGFR3 on sensory neurons to induce hyperexcitability and hypersensitivity.
#PainResearch #Autoimmunity
Pathogenic Role of FGFR3 Autoantibodies in Small Fiber Neuropathy
Sensory neuronopathies (SNN) and small fiber neuropathies (SFN) are debilitating disorders associated with neuropathic pain, yet their underlying mechanisms remain poorly understood. Autoantibodies ag...
www.biorxiv.org
1 3 6
Reposted by Nivedita Sarveswaran
crick.ac.uk
The Francis Crick Institute @crick.ac.uk · 6d
We're now recruiting early career group leaders at the Crick to lead ambitious research programmes and explore bold scientific questions.

Hear our Director, Edith Heard, explain why the Crick is a unique place for curiosity-driven research.

Apply now ➡️ www.crick.ac.uk/careers-stud...
110 140
neuroniv.bsky.social
Nivedita Sarveswaran @neuroniv.bsky.social · 7d
Well, they missed out on how morale-boosting Fire Elmo has become 🔥🔥
2
neuroniv.bsky.social
Nivedita Sarveswaran @neuroniv.bsky.social · 7d
More memes in lab meetings!
2 2
Reposted by Nivedita Sarveswaran
ritastrack.bsky.social
Rita Strack @ritastrack.bsky.social · 7d
I hope this Nobel Prize gets people talking meaningfully about our amazing immune systems and the importance of basic research to human health (and funding basic research).

I am also glad young women get to see that women can not only work at this level, but that those who do can get recognized.
2 43 190
Reposted by Nivedita Sarveswaran
micromotility.bsky.social
Kirsty Wan @micromotility.bsky.social · 8d
Very sad to hear that Sir John Gurdon, former Master of Magdalene College, has passed away at the age of 92. www.cam.ac.uk/research/new...

Here is a powerful reminder that you should never give up on your dreams.
6 11
Reposted by Nivedita Sarveswaran
jamesbriscoe.bsky.social
James Briscoe @jamesbriscoe.bsky.social · 8d
Very sad news, John Gurdon has died.

A developmental biologist's developmental biologist, Nobel prize winner

His work is the foundation of much of today's dev & stem cell bio.

An inspiration to many, including me. Always asking questions & wanting the answers

www.magd.cam.ac.uk/news/profess...
Professor Sir John Gurdon FRS (1933-2025) | Magdalene College
Magdalene College is deeply saddened to announce the death of Professor Sir John Gurdon FRS, who served as Master of the College from 1995 to 2002.
www.magd.cam.ac.uk
7 100 190
Reposted by Nivedita Sarveswaran
natrevdrugdiscov.nature.com
Nature Reviews Drug Discovery @natrevdrugdiscov.nature.com · 8d
Our latest research highlight covers a paper in Cell on the computational de novo design of a peptide modulator that addresses voltage-gated sodium channel dysfunction linked to epilepsy and cardiac arrhythmias nature.com/articles/d41...
Designer peptide retunes channel function
Discover the world’s best science and medicine | Nature.com
nature.com
1 2
Reposted by Nivedita Sarveswaran
thecimr.bsky.social
Cambridge Institute for Medical Research @thecimr.bsky.social · 8d
Great to welcome our second cohort of students to our Masters in Molecular Mechanism of Human Disease today. Have a good year everyone!
Group of university students gathered on a staircase and landing
1 3
Reposted by Nivedita Sarveswaran
gg9761.bsky.social
George Goodwin @gg9761.bsky.social · 9d
Stuart Bevan and I are offering an exciting MRC DTP-funded PhD project exploring the mechanisms of pain in Long COVID.

Find out more about the project here:
🔗 tinyurl.com/3caseacv

Application deadline: 28th October

@wolfsonsparc.bsky.social y.social
@kingsioppn.bsky.social sioppn.bsky.social
1 6 8
neuroniv.bsky.social
Nivedita Sarveswaran @neuroniv.bsky.social · 9d
That is an excellent account handle 🔍
1
Reposted by Nivedita Sarveswaran
dav1dcg.bsky.social
David @dav1dcg.bsky.social · 9d
Higher-order interactions in neuronal function: From genes to ionic currents in biophysical models

Models in this study show that "a small subset of ion channel genes captures essential variability across neuronal subtypes".

www.pnas.org/doi/10.1073/...
Higher-order interactions in neuronal function: From genes to ionic currents in biophysical models | PNAS
Neuronal firing patterns are the consequence of precise variations in neuronal membrane potential, which are themselves shaped by multiple ionic cu...
www.pnas.org
2 5
Reposted by Nivedita Sarveswaran
tedpricethepainguy.bsky.social
Ted Price @tedpricethepainguy.bsky.social · 10d
Very convincing findings from the Gamper lab: www.jneurosci.org/content/45/3... somebody needs to figure out the source of this GABAergic tone within the DRG! As far as I can tell the origin of this remains speculative and needs molecular identification.
Peripheral Gating of Nociception Investigated with a Decerebrate, Arterially Perfused Preparation of the Rat
There is growing evidence that sensory neurons within the dorsal root ganglia (DRGs) are equipped with mechanisms for “gating” nociceptive information before it enters the central nervous system. Howe...
www.jneurosci.org
2 16
Reposted by Nivedita Sarveswaran
belllab.bsky.social
Andy Bell @belllab.bsky.social · 11d
New preprint from the spinal cord group at Glasgow. Anatomical and functional characterisation of spinal circuits for cold, from sensory neurons to the brain…..https://www.biorxiv.org/content/10.1101/2025.10.03.680240v1
Labelled axons of calb1+ spinal projection neurons innervate multiple brain targets associated with cold sensation and thermoregulation. Darkfield images of different brain areas including the postal parabrachial and periaqueductal grey are shown with axons of ascending cells in yellow.
2 6 20
Reposted by Nivedita Sarveswaran
michaelhendricks.bsky.social
Michael Hendricks 🇨🇦 @michaelhendricks.bsky.social · 12d
"The connectome is like a road map."
ATV catching big air, labelled "neuropeptides."
4 10 47