Jacob K McPherson
@jacobkmcpherson.bsky.social
PharmD, PhD Pharmacology
jacobkmcpherson.com
jacobkmcpherson.com
Reposted by Jacob K McPherson
Nature looks at what comes next for science as the US government reopens for business.🧪
The US government shutdown is over: what’s next for scientists
Government researchers are heading back to work, but questions about the size of research-budget cuts will extend into next year.
go.nature.com
November 15, 2025 at 11:35 PM
Nature looks at what comes next for science as the US government reopens for business.🧪
Reposted by Jacob K McPherson
"Anyone concerned with pandemics and their impact must be concerned with inequality." ⚖️ vs 🦠
#GlobalHealth #HealthInequities #PandemicPreparedness #IDSky #MedSky
#GlobalHealth #HealthInequities #PandemicPreparedness #IDSky #MedSky
Revealed: Inequality is making pandemics more likely, more deadly and more costly. ‘Inequality-pandemic cycle’ must be broken to achieve health security.
Read the report: www.unaids.org/sites/defaul...
Read the press release: www.unaids.org/en/resources...
Read the report: www.unaids.org/sites/defaul...
Read the press release: www.unaids.org/en/resources...
November 3, 2025 at 2:26 AM
"Anyone concerned with pandemics and their impact must be concerned with inequality." ⚖️ vs 🦠
#GlobalHealth #HealthInequities #PandemicPreparedness #IDSky #MedSky
#GlobalHealth #HealthInequities #PandemicPreparedness #IDSky #MedSky
Reposted by Jacob K McPherson
𝗧𝗵𝗲 𝘄𝗲𝗮𝗽𝗼𝗻𝗶𝘀𝗮𝘁𝗶𝗼𝗻 𝗮𝘀𝗽𝗲𝗰𝘁 𝗼𝗳 𝗵𝗲𝗮𝗹𝘁𝗵 𝗰𝗮𝗿𝗲
Attacks on medical personnel, facilities and services are increasing and are deliberate
www.bmj.com/content/391/...
#Gaza #Ukraine #Sudan #Congo #Yemen #Afghanistan #Haiti @msf.ca
Attacks on medical personnel, facilities and services are increasing and are deliberate
www.bmj.com/content/391/...
#Gaza #Ukraine #Sudan #Congo #Yemen #Afghanistan #Haiti @msf.ca
How attacking healthcare has become a strategy of war
Gaza, Ukraine, and Sudan have put a spotlight on attacks on healthcare facilities and staff in conflict zones. The BMJ looks at the data, which seem to show a new strategy of war: removing civilians’ ...
www.bmj.com
November 3, 2025 at 7:41 AM
𝗧𝗵𝗲 𝘄𝗲𝗮𝗽𝗼𝗻𝗶𝘀𝗮𝘁𝗶𝗼𝗻 𝗮𝘀𝗽𝗲𝗰𝘁 𝗼𝗳 𝗵𝗲𝗮𝗹𝘁𝗵 𝗰𝗮𝗿𝗲
Attacks on medical personnel, facilities and services are increasing and are deliberate
www.bmj.com/content/391/...
#Gaza #Ukraine #Sudan #Congo #Yemen #Afghanistan #Haiti @msf.ca
Attacks on medical personnel, facilities and services are increasing and are deliberate
www.bmj.com/content/391/...
#Gaza #Ukraine #Sudan #Congo #Yemen #Afghanistan #Haiti @msf.ca
Reposted by Jacob K McPherson
The third meeting of the Intergovernmental Working Group (IGWG) on the WHO Pandemic Agreement is taking place from:
🗓️ 3–7 November 2025
🕘 9:30–12:00 and 14:00–16:30 (CET) each day
Follow the webcast LIVE 👉 bit.ly/4oK8iuL
🗓️ 3–7 November 2025
🕘 9:30–12:00 and 14:00–16:30 (CET) each day
Follow the webcast LIVE 👉 bit.ly/4oK8iuL
November 3, 2025 at 8:30 AM
The third meeting of the Intergovernmental Working Group (IGWG) on the WHO Pandemic Agreement is taking place from:
🗓️ 3–7 November 2025
🕘 9:30–12:00 and 14:00–16:30 (CET) each day
Follow the webcast LIVE 👉 bit.ly/4oK8iuL
🗓️ 3–7 November 2025
🕘 9:30–12:00 and 14:00–16:30 (CET) each day
Follow the webcast LIVE 👉 bit.ly/4oK8iuL
Reposted by Jacob K McPherson
#Tirzepatide added to basal #insulin improved glycaemic control and was generally well tolerated, providing evidence to support its potential therapeutic use in patients with type 2 #diabetes in #China thelancet.com/journals/lan... #T2D
#MedSky #EndoSky
#MedSky #EndoSky
October 30, 2025 at 8:21 AM
#Tirzepatide added to basal #insulin improved glycaemic control and was generally well tolerated, providing evidence to support its potential therapeutic use in patients with type 2 #diabetes in #China thelancet.com/journals/lan... #T2D
#MedSky #EndoSky
#MedSky #EndoSky
Reposted by Jacob K McPherson
🧬 UPCOMING SPECIAL ISSUE 🧬
🔬 Single-Cell and Spatial Transcriptomics in Plants 🔬
📝 Edited by Shahid Mukhtar
📅 Deadline: 28 February 2026
📣 Got a suitable manuscript? Contact us: bit.ly/JXBissues
@smukhtarlab.bsky.social @sebiology.bsky.social
#JXBspecialissues #PlantScience 🧪
(1/2)
🔬 Single-Cell and Spatial Transcriptomics in Plants 🔬
📝 Edited by Shahid Mukhtar
📅 Deadline: 28 February 2026
📣 Got a suitable manuscript? Contact us: bit.ly/JXBissues
@smukhtarlab.bsky.social @sebiology.bsky.social
#JXBspecialissues #PlantScience 🧪
(1/2)
October 22, 2025 at 2:07 PM
🧬 UPCOMING SPECIAL ISSUE 🧬
🔬 Single-Cell and Spatial Transcriptomics in Plants 🔬
📝 Edited by Shahid Mukhtar
📅 Deadline: 28 February 2026
📣 Got a suitable manuscript? Contact us: bit.ly/JXBissues
@smukhtarlab.bsky.social @sebiology.bsky.social
#JXBspecialissues #PlantScience 🧪
(1/2)
🔬 Single-Cell and Spatial Transcriptomics in Plants 🔬
📝 Edited by Shahid Mukhtar
📅 Deadline: 28 February 2026
📣 Got a suitable manuscript? Contact us: bit.ly/JXBissues
@smukhtarlab.bsky.social @sebiology.bsky.social
#JXBspecialissues #PlantScience 🧪
(1/2)
Reposted by Jacob K McPherson
Just out: Modeling cryo-EM structures in alternative states with AlphaFold2-based models and density-guided simulations
Modeling cryo-EM structures in alternative states with AlphaFold2-based models and density-guided simulations
Communications Chemistry, Published online: 30 October 2025; doi:10.1038/s42004-025-01751-4Accurate modeling of atomic coordinates into cryo-electron microscopy maps is challenging for proteins with multiple functional states, especially without suitable templates and at low resolutions. Here, the authors employ a refinement approach combining AlphaFold2, clustering, and density-guided simulations, enhancing model accuracy for membrane proteins undergoing significant conformational changes.
bit.ly
October 30, 2025 at 9:07 AM
Just out: Modeling cryo-EM structures in alternative states with AlphaFold2-based models and density-guided simulations
Reposted by Jacob K McPherson
🪰 folks! Despite Harvard lawsuit outcome, FlyBase NIH grant was not released. FlyBase now runs on the public, like NPR, PBS etc. If we don't step up, it can go away! Donations site on flybase.org homepage. Note: it links to IU stock center, but its for FlyBase, see instructions. pls give+share! 2/2
FlyBase Homepage
FlyBase: a database for drosophila genetics and molecular biology
flybase.org
October 29, 2025 at 12:31 PM
🪰 folks! Despite Harvard lawsuit outcome, FlyBase NIH grant was not released. FlyBase now runs on the public, like NPR, PBS etc. If we don't step up, it can go away! Donations site on flybase.org homepage. Note: it links to IU stock center, but its for FlyBase, see instructions. pls give+share! 2/2
Reposted by Jacob K McPherson
My opinion on the decline of our national pandemic preparedness and risks to biosecurity in @issuesinst.bsky.social @nationalacademies.org
issues.org/unprepared-p...
issues.org/unprepared-p...
October 28, 2025 at 9:18 PM
My opinion on the decline of our national pandemic preparedness and risks to biosecurity in @issuesinst.bsky.social @nationalacademies.org
issues.org/unprepared-p...
issues.org/unprepared-p...
Reposted by Jacob K McPherson
Is childhood exposure to local wealth inequality associated with upward income mobility achieved in adulthood? Yes! Check out my new paper, just published in @natureportfolio.nature.com here: doi.org/10.1038/s414... #EconSky #Sociology #Demography
October 15, 2025 at 12:11 PM
Is childhood exposure to local wealth inequality associated with upward income mobility achieved in adulthood? Yes! Check out my new paper, just published in @natureportfolio.nature.com here: doi.org/10.1038/s414... #EconSky #Sociology #Demography
Reposted by Jacob K McPherson
Congrats to Yancong, Amrisha, Xochitl, Eric and all co-authors!!!
Predicting functions of uncharacterized gene products from microbial communities - @hutlab.bsky.social @hsph.harvard.edu @broadinstitute.org go.nature.com/435C4lp
Predicting functions of uncharacterized gene products from microbial communities - Nature Biotechnology
FUGAsseM predicts protein function in microbiomes using coexpression patterns from metatranscriptomes and diverse community-wide data.
go.nature.com
October 17, 2025 at 3:36 PM
Congrats to Yancong, Amrisha, Xochitl, Eric and all co-authors!!!
There’s something about field biology that just can’t be replicated or fully understood through computational or physical sciences alone.
"Sitting in a lecture hall and taking laboratory courses are not the same as going out into the field and doing it yourself”
go.nature.com/4oOdX35
go.nature.com/4oOdX35
Cold plunge: how I gained hands-on experience in marine biology
Matthew Kim learnt how to conduct research while studying in a small Canadian town for a semester.
go.nature.com
October 20, 2025 at 2:29 PM
There’s something about field biology that just can’t be replicated or fully understood through computational or physical sciences alone.
Reposted by Jacob K McPherson
I just made an account and voted for this biology laboratory made of LEGO to "promote biological research and inspire more people into the world of biology". They need 10K votes. Reposting and/or voting below would be helpful. 🤗
beta.ideas.lego.com/product-idea...
beta.ideas.lego.com/product-idea...
Biological Laboratory | LEGO® Ideas
This is a two-floor realistic Biological Laboratory building. In this design, I try to tell stories about biologists, introduce biology concepts to general publ…
beta.ideas.lego.com
October 16, 2025 at 8:07 AM
I just made an account and voted for this biology laboratory made of LEGO to "promote biological research and inspire more people into the world of biology". They need 10K votes. Reposting and/or voting below would be helpful. 🤗
beta.ideas.lego.com/product-idea...
beta.ideas.lego.com/product-idea...
Reposted by Jacob K McPherson
🎉 Celebrate #WorldTeachersDay with @femsmicro.org Microbiology Letters' latest issue: Learning Together for Our Future. Discover global perspectives on science education, public engagement & inclusivity.
🔗 oxford.ly/3VGDpLg
🔗 oxford.ly/3VGDpLg
October 5, 2025 at 2:00 PM
🎉 Celebrate #WorldTeachersDay with @femsmicro.org Microbiology Letters' latest issue: Learning Together for Our Future. Discover global perspectives on science education, public engagement & inclusivity.
🔗 oxford.ly/3VGDpLg
🔗 oxford.ly/3VGDpLg
Reposted by Jacob K McPherson
Reposted by Jacob K McPherson
Jane Goodall was my first childhood hero, as I loved animals as a kid and was inspired by her story. I still remember the National Geographic specials about her. RIP.
October 1, 2025 at 8:05 PM
Jane Goodall was my first childhood hero, as I loved animals as a kid and was inspired by her story. I still remember the National Geographic specials about her. RIP.
Reposted by Jacob K McPherson
The world has lost its most powerful advocate for nature and hope. Yet many remain who will continue her legacy and I know she will continue to inspire generations more.
October 1, 2025 at 6:01 PM
The world has lost its most powerful advocate for nature and hope. Yet many remain who will continue her legacy and I know she will continue to inspire generations more.
Reposted by Jacob K McPherson
Come join us 2-4th March 2026 for a cracking #microbiome conference in Hinxton UK! Speaker line up is AMAZING and lots of opportunities for ECRs for selected talks, flash talks and posters.
Bursaries are also available!
See details below 👇
Bursaries are also available!
See details below 👇
Showcase your microbiome research at our 2026 conference! #Microbiome26
Demonstrate how #genomics tools and technologies are contributing to a deeper understanding of the microbiome.
🗓️ 2-4 March
Submit an abstract by 24 November ✍🏼
📎 bit.ly/4kttBOX
#MicrobiomeSky #AcademicSky
Demonstrate how #genomics tools and technologies are contributing to a deeper understanding of the microbiome.
🗓️ 2-4 March
Submit an abstract by 24 November ✍🏼
📎 bit.ly/4kttBOX
#MicrobiomeSky #AcademicSky
September 30, 2025 at 7:22 AM
Come join us 2-4th March 2026 for a cracking #microbiome conference in Hinxton UK! Speaker line up is AMAZING and lots of opportunities for ECRs for selected talks, flash talks and posters.
Bursaries are also available!
See details below 👇
Bursaries are also available!
See details below 👇
Reposted by Jacob K McPherson
Showcase your microbiome research at our 2026 conference! #Microbiome26
Demonstrate how #genomics tools and technologies are contributing to a deeper understanding of the microbiome.
🗓️ 2-4 March
Submit an abstract by 24 November ✍🏼
📎 bit.ly/4kttBOX
#MicrobiomeSky #AcademicSky
Demonstrate how #genomics tools and technologies are contributing to a deeper understanding of the microbiome.
🗓️ 2-4 March
Submit an abstract by 24 November ✍🏼
📎 bit.ly/4kttBOX
#MicrobiomeSky #AcademicSky
September 30, 2025 at 7:00 AM
Showcase your microbiome research at our 2026 conference! #Microbiome26
Demonstrate how #genomics tools and technologies are contributing to a deeper understanding of the microbiome.
🗓️ 2-4 March
Submit an abstract by 24 November ✍🏼
📎 bit.ly/4kttBOX
#MicrobiomeSky #AcademicSky
Demonstrate how #genomics tools and technologies are contributing to a deeper understanding of the microbiome.
🗓️ 2-4 March
Submit an abstract by 24 November ✍🏼
📎 bit.ly/4kttBOX
#MicrobiomeSky #AcademicSky
Reposted by Jacob K McPherson
New research article
WHO global gonococcal antimicrobial surveillance programmes, 2019–22: a retrospective observational study
www.thelancet.com/journals/lan...
#IDSky #ClinMicro #Gonorrhoea #Gonorrhea #AMR #OpenAccess #OA
WHO global gonococcal antimicrobial surveillance programmes, 2019–22: a retrospective observational study
www.thelancet.com/journals/lan...
#IDSky #ClinMicro #Gonorrhoea #Gonorrhea #AMR #OpenAccess #OA
September 24, 2025 at 1:18 PM
New research article
WHO global gonococcal antimicrobial surveillance programmes, 2019–22: a retrospective observational study
www.thelancet.com/journals/lan...
#IDSky #ClinMicro #Gonorrhoea #Gonorrhea #AMR #OpenAccess #OA
WHO global gonococcal antimicrobial surveillance programmes, 2019–22: a retrospective observational study
www.thelancet.com/journals/lan...
#IDSky #ClinMicro #Gonorrhoea #Gonorrhea #AMR #OpenAccess #OA
Reposted by Jacob K McPherson
Which is better? Lactated Ringer’s solution or normal saline?
The latest video in our partnership with @glaucomflecken.bsky.social summarizes the FLUID trial. 👉 nej.md/DrG26
#MedSky #MedEd #Surgery
The latest video in our partnership with @glaucomflecken.bsky.social summarizes the FLUID trial. 👉 nej.md/DrG26
#MedSky #MedEd #Surgery
September 23, 2025 at 7:04 PM
Which is better? Lactated Ringer’s solution or normal saline?
The latest video in our partnership with @glaucomflecken.bsky.social summarizes the FLUID trial. 👉 nej.md/DrG26
#MedSky #MedEd #Surgery
The latest video in our partnership with @glaucomflecken.bsky.social summarizes the FLUID trial. 👉 nej.md/DrG26
#MedSky #MedEd #Surgery
Reposted by Jacob K McPherson
New report brings together the thinking of experts across the world on what a powerful and effective narrative could look like on PUBLIC GOOD
@jonathanglennie.bsky.social & @benphillips76.bsky.social
globalcooperation.institute/public-good-...
@jonathanglennie.bsky.social & @benphillips76.bsky.social
globalcooperation.institute/public-good-...
Public Good Narrative Project - Global Cooperation Institute
September 2025
globalcooperation.institute
September 23, 2025 at 8:06 PM
New report brings together the thinking of experts across the world on what a powerful and effective narrative could look like on PUBLIC GOOD
@jonathanglennie.bsky.social & @benphillips76.bsky.social
globalcooperation.institute/public-good-...
@jonathanglennie.bsky.social & @benphillips76.bsky.social
globalcooperation.institute/public-good-...
Reposted by Jacob K McPherson
More than 62,000 people in Europe may have died from heat-related causes in the summer of 2024, according to a study in Nature Medicine. The authors also suggest a new early-warning system that can reliably predict heat-health emergencies at least 1 week in advance. go.nature.com/48vdZrn 🧪
September 22, 2025 at 10:32 PM
More than 62,000 people in Europe may have died from heat-related causes in the summer of 2024, according to a study in Nature Medicine. The authors also suggest a new early-warning system that can reliably predict heat-health emergencies at least 1 week in advance. go.nature.com/48vdZrn 🧪
Reposted by Jacob K McPherson
At the Berlin node of a global hackathon, teams raced to develop artificial intelligence tools to accelerate the design of drugs and materials. https://scim.ag/3VuZyvR
Researchers customize AI tools at global ‘hackathon’
More than 1200 scientists and developers explore how large language models can be applied to materials science and chemistry
www.science.org
September 22, 2025 at 11:12 PM
At the Berlin node of a global hackathon, teams raced to develop artificial intelligence tools to accelerate the design of drugs and materials. https://scim.ag/3VuZyvR