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Nature Biotechnology
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Publishing the best of biotech science and business. Find us on Twitter, Facebook & Instagram. Part of @natureportfolio.nature.com‬.
Recent patents relating to compositions and methods for preventing or treating diseases and conditions associated with mitochondrial dysfunction go.nature.com/4tjp1YG
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Mitochondrial diseases - Nature Biotechnology
Recent patents relating to compositions and methods for preventing or treating diseases and conditions associated with mitochondrial dysfunction.
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February 5, 2026 at 4:12 PM
DNA repair activity of reverse transcriptase may negatively affect prime editing precision go.nature.com/3X6mOBv
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The reverse transcriptase domain of prime editors contributes to DNA repair in mammalian cells - Nature Biotechnology
DNA repair activity of reverse transcriptase may negatively affect prime editing precision.
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February 5, 2026 at 2:01 AM
Insights into regulatory T cell biology are accelerating therapeutic innovation in cancer immunotherapy, autoimmune diseases and transplant rejection go.nature.com/4qNezXD
February 4, 2026 at 10:21 PM
Balancing innovation and integrity: the biomedical research ecosystem at a crossroads - @fralinbiomed.bsky.social @virginiatech.bsky.social go.nature.com/3MqlHdP
February 4, 2026 at 5:21 PM
Accurate plasmid reconstruction from metagenomics data using assembly–alignment graphs and contrastive learning - @ucph.bsky.social @novo-nordisk.bsky.social go.nature.com/4qcOb8H
Accurate plasmid reconstruction from metagenomics data using assembly–alignment graphs and contrastive learning - Nature Biotechnology
PlasMAAG uses cross-sample information to improve plasmid reconstruction from metagenomic samples.
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February 4, 2026 at 4:36 PM
Pilot phase clinical trial of a wearable, electrochemical aptamer-based patch for continuous drug concentration measurement - @sydney.edu.au @ucsantabarbara.bsky.social go.nature.com/46q2uQ7
Pilot phase clinical trial of a wearable, electrochemical aptamer-based patch for continuous drug concentration measurement - Nature Biotechnology
A wearable that continuously measures the concentration of a drug is demonstrated in humans.
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February 4, 2026 at 4:24 PM
Profiling transcriptional crosstalk between promoters and cell-type-specific enhancers allows large gene cargo delivery go.nature.com/4kFUnEO
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Spatial genomics of AAV vectors reveals mechanism of transcriptional crosstalk that enables targeted delivery of large genetic cargo - Nature Biotechnology
Profiling transcriptional crosstalk between promoters and cell-type-specific enhancers allows large gene cargo delivery.
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February 4, 2026 at 2:07 AM
Research Highlight: Gene drives tested against real-world malaria diversity www.nature.com/articles/s41...
February 4, 2026 at 1:46 AM
San Diego based Debut Biotechnology creates a lab version of orris, a floral scent that can cost as much as gold, that has been used in perfume making and in medicine since the time of the Ancient Greeks www.nature.com/articles/s41...
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Fancy smelling like a Greek goddess? - Nature Biotechnology
Nature Biotechnology - Fancy smelling like a Greek goddess?
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February 3, 2026 at 3:32 PM
Placement of an m7G cap internally on circular RNAs promotes their translation in vivo go.nature.com/4b37Thj
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Internal cap-initiated translation for efficient protein production from circular mRNA - Nature Biotechnology
Placement of an m7G cap internally on circular RNAs promotes their translation in vivo.
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February 3, 2026 at 12:58 PM
Biotech news from around the world: India, South Korea, Brazil, Belgium www.nature.com/articles/s41...
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Biotech news from around the world - Nature Biotechnology
Nature Biotechnology - Biotech news from around the world
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February 2, 2026 at 9:17 PM
Building an effective and sustainable technology commercialization fund emphasizes getting industry input early to improve outcomes in the short and long term go.nature.com/4bRcKo3
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Sustainability of gap funding programs aimed at commercializing academic innovation - Nature Biotechnology
Rutgers University’s approach to building an effective and sustainable technology commercialization fund emphasizes getting industry input early to improve outcomes in the short and long term.
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February 2, 2026 at 5:41 PM
Customizing CRISPR–Cas PAM specificity with protein language models - @thisismadani.bsky.social go.nature.com/4a4G9Zy
Customizing CRISPR–Cas PAM specificity with protein language models - Nature Biotechnology
The protospacer-adjacent motif specificity of several Cas enzymes is customized using protein language models.
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February 2, 2026 at 4:07 PM
First-in-human studies provide hope that islet replacement therapies derived from stem cells will prove safe and effective in people with type 1 diabetes, but hurdles remain www.nature.com/articles/s41...
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Lab-made islet cell implants sail through diabetes trials, but are they ready yet? - Nature Biotechnology
First-in-human studies provide hope that islet replacement therapies derived from stem cells will prove safe and effective in people with type 1 diabetes, but hurdles remain.
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January 30, 2026 at 6:05 PM
A neural network model improves time-lapse super-resolution imaging of live cells go.nature.com/3EjfqMQ
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A neural network for long-term super-resolution imaging of live cells with reliable confidence quantification - Nature Biotechnology
A neural network model improves time-lapse super-resolution imaging of live cells.
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January 30, 2026 at 3:40 AM
A systematic, prospective analysis of the interplay between science and technology in biomedicine can illuminate the pathway for translating scientific insights into tangible innovations for societal benefit go.nature.com/4bbgxfR
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Mapping the science–technology translational landscape in biomedicine - Nature Biotechnology
A systematic, prospective analysis of the interplay between science and technology in biomedicine can illuminate the pathway for translating scientific insights into tangible innovations for societal ...
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January 30, 2026 at 2:45 AM
Obituary: John Gurdon (1933–2025) - @zernickagoetz.bsky.social go.nature.com/3Mf8SD0
John Gurdon 1933–2025 - Nature Biotechnology
Nature Biotechnology - John Gurdon 1933–2025
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January 29, 2026 at 9:25 PM
Fancy smelling like a Greek goddess? www.nature.com/articles/s41...
Fancy smelling like a Greek goddess? - Nature Biotechnology
Nature Biotechnology - Fancy smelling like a Greek goddess?
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January 29, 2026 at 8:19 PM
In Brief: @gsk.bsky.social selects its first two biotech collaborators from venture capital Flagship Pioneer’s bioplatform companies, part of a $7.2 billion pact between the pharma and VC forged in 2024 www.nature.com/articles/s41...
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GSK picks first Flagship biotechs - Nature Biotechnology
Nature Biotechnology - GSK picks first Flagship biotechs
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January 29, 2026 at 6:00 PM
Biologics are delivered to the gut using phage that infects resident commensal bacteria go.nature.com/4jWgRAW
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Sustained in situ protein production and release in the mammalian gut by an engineered bacteriophage - Nature Biotechnology
Biologics are delivered to the gut using phage that infects resident commensal bacteria.
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January 29, 2026 at 2:18 AM
Recent moves of note in and around the biotech and pharma industries go.nature.com/4q6Xxmv
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People - Nature Biotechnology
Recent moves of note in and around the biotech and pharma industries.
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January 28, 2026 at 6:39 PM
Lipid nanoparticles carrying plasmid DNA and an inflammation inhibitor enable longer transgene expression than mRNA nanoparticles go.nature.com/3EkClak
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Safer non-viral DNA delivery using lipid nanoparticles loaded with endogenous anti-inflammatory lipids - Nature Biotechnology
Lipid nanoparticles carrying plasmid DNA and an inflammation inhibitor enable longer transgene expression than mRNA nanoparticles.
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January 28, 2026 at 4:29 AM
China’s innovation in translational medicine: rethinking early-stage clinical development - @caidyacro.bsky.social go.nature.com/4agbEkG
January 27, 2026 at 5:58 PM
Sidewinder uses DNA three‑way junctions (3WJs) to construct long, complex, and highly diverse synthetic DNA sequences. #NBThighlight www.nature.com/articles/s41...
Construction of complex and diverse DNA sequences using DNA three-way junctions - Nature
Sidewinder enables high-fidelity DNA assembly by separating the information that guides assembly from the final assembled sequence.
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January 27, 2026 at 11:33 AM