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Our editors pick their favorite research articles from 2025 go.nature.com/4oCK84L
December 12, 2025 at 5:21 PM
The December issue is live nature.com/nbt/volumes/...

Hybrid quantum computing for drug design. Ghazi Vakili et al. present a hybrid quantum–classical generative model to design molecules to inhibit KRAS activity. Two candidates are synthesized and further characterized go.nature.com/3EitbLm
December 12, 2025 at 3:09 PM
2025: research in review go.nature.com/4oCK84L
December 8, 2025 at 7:47 PM
Beyond the unprecedented efficacy of GLP-1s in obesity and type 2 diabetes, evidence that they improve comorbidities has been accumulating at an impressive pace in recent years go.nature.com/49aN7gR
December 3, 2025 at 2:11 PM
As pharma ramps up efforts on disorders of aging, a new era of disease prevention comes into focus go.nature.com/49aN7gR
November 25, 2025 at 3:13 PM
Patenting biopharmaceutical inventions that use artificial intelligence in China go.nature.com/43yWi78
November 17, 2025 at 7:00 PM
Are GLP-1s the first longevity drugs? go.nature.com/49aN7gR
November 12, 2025 at 8:42 PM
The November issue is live nature.com/nbt/volumes/...

On the cover, lipid nanoparticles targeting the lung, designed using neural networks. A method developed by Witten et al. identified two structures that efficiently delivered mRNA to ferret lungs go.nature.com/4fbj0VU
November 12, 2025 at 7:03 PM
While medical digital twins hold great promise for personalized healthcare—with promising applications in oncology, diabetes management and cardiovascular medicine—their implementation is no easy feat. We asked experts in the field for their thoughts go.nature.com/42YcE9c
rdcu.be/eOir8
November 4, 2025 at 9:30 PM
New approaches to engineering plant immunity can more broadly protect crops against pathogens and disease, once they get through regulatory hurdles go.nature.com/475WgV7
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November 3, 2025 at 9:02 PM
How AI is supercharging antibiotic discovery #NBTintheNews www.gene.com/stories/how-...
October 30, 2025 at 8:14 PM
Applications of digital twins in medicine go.nature.com/42YcE9c
October 24, 2025 at 1:30 PM
Vicković Lab publishes a new study on colon aging #NBTintheNews via @cancerdynamics.bsky.social cancerdynamics.columbia.edu/news/vickovi...
October 23, 2025 at 9:22 PM
After an evaluation of various technologies, long-read whole-genome sequencing is at present the only reliable approach to confirm the absence of foreign DNA in genome-edited crops go.nature.com/3WbbKlW
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October 22, 2025 at 6:08 PM
Rewriting the code of plant immunity go.nature.com/475WgV7
October 14, 2025 at 8:25 PM
The October issue is live nature.com/nbt/volumes/...

The cover shows perturbations that convert stem-like, atypical teratoid rhabdoid tumor (AT/RT) cells into a more differentiated, neuron-like state go.nature.com/4hXER5O
October 14, 2025 at 4:12 PM
Programmable promoter editing for precise control of transgene expression - @mitcheme.bsky.social @mitdeptofbe.bsky.social go.nature.com/4h9wlR1
October 13, 2025 at 7:11 PM
Engineered pattern recognition receptors enhance broad-spectrum plant resistance - @zmbp-tuebingen.bsky.social go.nature.com/474nnA9
October 13, 2025 at 6:59 PM
The COP16 decision established a multilateral mechanism for digital sequence information benefit-sharing. DSI researchers assess what has been accomplished so far and identify remaining challenges go.nature.com/4nBE4t8
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October 3, 2025 at 8:08 PM
October 10- Deadline to submit abstracts and grab an early bird registration for our event on nucleic acid medicine with these experts. Learn more> go.nature.com/4mhVASr
October 3, 2025 at 3:26 PM
Behind the paper: Connecting siloed high-content screens communities.springernature.com/posts/connec...
October 3, 2025 at 2:47 PM
Funding and public support for vaccines in the United States is at an all-time low. Promising research is resulting in effective antivirals, but they should not take the place of vaccines go.nature.com/4gijtYv
September 29, 2025 at 4:03 PM
Cultivated meat faces escalating intellectual property issues as the industry expands, including conventional patent rights, the private IP rights of animal breeders and the Convention on Biological Diversity go.nature.com/3K5Aj0O
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September 24, 2025 at 12:42 PM
A vast landscape of ‘undruggable’ cancer targets remains beyond the reach of conventional therapeutic agents. Recent advances in artificial intelligence are challenging this paradigm go.nature.com/4fHNMYi
September 23, 2025 at 5:44 PM
Inspired by bacteria’s defense strategies, scientists pioneer a novel method for genome editing #NBTintheNews via @helmholtzhzi.bsky.social www.helmholtz-hzi.de/en/media-cen...
September 22, 2025 at 6:44 PM