Izabela Zakrocka
@izabelazakrocka.bsky.social
Internist, nephrologist, transplantologist, Assistant Professor at Medical University of Lublin, #Glomcon 2021-2022 Fellow, ERA YNP Representative of Poland 🇵🇱, Board of Polish Young Transplantologists #NephSky #KidneyOmics #PharmKidney
Reposted by Izabela Zakrocka
Our take on the baxdrostat PA trial in @asnpublications.bsky.social #KidneyNews
www.kidneynews.org/view/journal... with @nephroseeker.medsky.social and @dramiliflores.bsky.social !
Thanks to Sam Kant and @kdjhaveri.bsky.social for the invite!!
www.kidneynews.org/view/journal... with @nephroseeker.medsky.social and @dramiliflores.bsky.social !
Thanks to Sam Kant and @kdjhaveri.bsky.social for the invite!!
December 9, 2025 at 2:33 AM
Our take on the baxdrostat PA trial in @asnpublications.bsky.social #KidneyNews
www.kidneynews.org/view/journal... with @nephroseeker.medsky.social and @dramiliflores.bsky.social !
Thanks to Sam Kant and @kdjhaveri.bsky.social for the invite!!
www.kidneynews.org/view/journal... with @nephroseeker.medsky.social and @dramiliflores.bsky.social !
Thanks to Sam Kant and @kdjhaveri.bsky.social for the invite!!
Reposted by Izabela Zakrocka
Excited about this @theisn.org initiative, especially under the leadership of @hswapnil.medsky.social as EIC. Nephrology needed this
www.theisn.org/blog/2025/12...
www.theisn.org/blog/2025/12...
Turning clinical experience into shared knowledge: ISN launches Kidney International Case ReportsTM - International Society of Nephrology
www.theisn.org
December 9, 2025 at 4:11 AM
Excited about this @theisn.org initiative, especially under the leadership of @hswapnil.medsky.social as EIC. Nephrology needed this
www.theisn.org/blog/2025/12...
www.theisn.org/blog/2025/12...
Reposted by Izabela Zakrocka
December 3, 2025 at 10:42 PM
Reposted by Izabela Zakrocka
Here is today’s #eyeSCANdy! Scanning EM of RBCs (including acanthocytes) within a capillary loop from a glomerulus with crescent formation.
Photo courtesy of Dr. Stephen Bonsib. #renal #pathology #kidneypath
Photo courtesy of Dr. Stephen Bonsib. #renal #pathology #kidneypath
December 3, 2025 at 2:03 PM
Here is today’s #eyeSCANdy! Scanning EM of RBCs (including acanthocytes) within a capillary loop from a glomerulus with crescent formation.
Photo courtesy of Dr. Stephen Bonsib. #renal #pathology #kidneypath
Photo courtesy of Dr. Stephen Bonsib. #renal #pathology #kidneypath
Reposted by Izabela Zakrocka
Looking forward to the ASSENT ( #Alport syndrome surrogate endpoints network) meeting today with the FDA. We need new effective therapies and paving a regulatory path is the first step.
December 2, 2025 at 12:28 PM
Looking forward to the ASSENT ( #Alport syndrome surrogate endpoints network) meeting today with the FDA. We need new effective therapies and paving a regulatory path is the first step.
Reposted by Izabela Zakrocka
Maybe the most shocking study from #KidneyWk.
🐚From the depths of the oceans to #BlueSky, we're discussing PISCES 🐟 12/2/25 9pm EST. #NephJC
Are you hooked🪝on fish oil for CV disease in ESRD, or are you throwing it back 🌊?
www.nephjc.com/news/pisces-fishoil
🐚From the depths of the oceans to #BlueSky, we're discussing PISCES 🐟 12/2/25 9pm EST. #NephJC
Are you hooked🪝on fish oil for CV disease in ESRD, or are you throwing it back 🌊?
www.nephjc.com/news/pisces-fishoil
Fish Oil in Dialysis: A Big Catch or an Empty Net — NephJC
Holy Mackerel! This week we will discuss fish oil use in maintenance hemodialysis patients. Could this be the one thing that bends the curve on CV mortality, or is it just a red herring?
www.nephjc.com
December 1, 2025 at 6:41 PM
Maybe the most shocking study from #KidneyWk.
🐚From the depths of the oceans to #BlueSky, we're discussing PISCES 🐟 12/2/25 9pm EST. #NephJC
Are you hooked🪝on fish oil for CV disease in ESRD, or are you throwing it back 🌊?
www.nephjc.com/news/pisces-fishoil
🐚From the depths of the oceans to #BlueSky, we're discussing PISCES 🐟 12/2/25 9pm EST. #NephJC
Are you hooked🪝on fish oil for CV disease in ESRD, or are you throwing it back 🌊?
www.nephjc.com/news/pisces-fishoil
Reposted by Izabela Zakrocka
This is so exciting 🤩
Just a reminder that many big things in medicine started from case reports
Just a reminder that many big things in medicine started from case reports
December 1, 2025 at 3:00 PM
This is so exciting 🤩
Just a reminder that many big things in medicine started from case reports
Just a reminder that many big things in medicine started from case reports
Reposted by Izabela Zakrocka
Looking forward to reading about high quality #Nephrology case reports in @isnkidneycare.bsky.social new journal to be led by @hswapnil.medsky.social and @arvindcanchi.bsky.social
#Nephpearls #NephSky
👉 www.sciencedirect.com/journal/kidn...
#Nephpearls #NephSky
👉 www.sciencedirect.com/journal/kidn...
December 1, 2025 at 3:10 PM
Looking forward to reading about high quality #Nephrology case reports in @isnkidneycare.bsky.social new journal to be led by @hswapnil.medsky.social and @arvindcanchi.bsky.social
#Nephpearls #NephSky
👉 www.sciencedirect.com/journal/kidn...
#Nephpearls #NephSky
👉 www.sciencedirect.com/journal/kidn...
Reposted by Izabela Zakrocka
Excited to join hands with @hswapnil.medsky.social & @theisn.org in this new venture, Kidney International Case Reports.
KICR seeks submissions from authors worldwide - Publication fees will be waived for all authors between Dec 1, 2025, and Dec 31, 2026.
www.sciencedirect.com/journal/kidn...
KICR seeks submissions from authors worldwide - Publication fees will be waived for all authors between Dec 1, 2025, and Dec 31, 2026.
www.sciencedirect.com/journal/kidn...
December 1, 2025 at 5:03 PM
Excited to join hands with @hswapnil.medsky.social & @theisn.org in this new venture, Kidney International Case Reports.
KICR seeks submissions from authors worldwide - Publication fees will be waived for all authors between Dec 1, 2025, and Dec 31, 2026.
www.sciencedirect.com/journal/kidn...
KICR seeks submissions from authors worldwide - Publication fees will be waived for all authors between Dec 1, 2025, and Dec 31, 2026.
www.sciencedirect.com/journal/kidn...
Reposted by Izabela Zakrocka
Reposted by Izabela Zakrocka
Congratulations to @hswapnil.medsky.social, new Editor in Chief of Kidney International Case Reports! www.sciencedirect.com/journal/kidn...
December 1, 2025 at 3:09 PM
Congratulations to @hswapnil.medsky.social, new Editor in Chief of Kidney International Case Reports! www.sciencedirect.com/journal/kidn...
Reposted by Izabela Zakrocka
📢 The ISN launches Kidney International Case Reports, a new open-access journal with case reports, short communications, & commentaries offering real-world clinical insights in kidney care. Rapid peer review & free publication until Dec 31, 2026 👉 www.sciencedirect.co... @hswapnil.medsky.social
December 1, 2025 at 3:10 PM
📢 The ISN launches Kidney International Case Reports, a new open-access journal with case reports, short communications, & commentaries offering real-world clinical insights in kidney care. Rapid peer review & free publication until Dec 31, 2026 👉 www.sciencedirect.co... @hswapnil.medsky.social
Reposted by Izabela Zakrocka
RPS and Banff Activity/Chronicity Working Group
WITH REGISTRATION LINK
us02web.zoom.us/webinar/regi...
#renalpath #pathsky #nephsky #nephrology
WITH REGISTRATION LINK
us02web.zoom.us/webinar/regi...
#renalpath #pathsky #nephsky #nephrology
November 28, 2025 at 8:15 PM
RPS and Banff Activity/Chronicity Working Group
WITH REGISTRATION LINK
us02web.zoom.us/webinar/regi...
#renalpath #pathsky #nephsky #nephrology
WITH REGISTRATION LINK
us02web.zoom.us/webinar/regi...
#renalpath #pathsky #nephsky #nephrology
Reposted by Izabela Zakrocka
OMG! A nationally televised commercial for urine albumin to creatinine ratio!
November 27, 2025 at 4:37 PM
OMG! A nationally televised commercial for urine albumin to creatinine ratio!
Reposted by Izabela Zakrocka
It began in 2021, wondering why anyone would pick me for #NSMC. I applied in '22 and was surprised to be accepted. I’ve grown thanks to many of you (@hswapnil.medsky.social @kidneyboy.bsky.social ), though I still feel like a newcomer 😊
🙏 Grateful to be in this with @brianrifkin.bsky.social #NephJC
🙏 Grateful to be in this with @brianrifkin.bsky.social #NephJC
An announcement
www.nephjc.com/news/2025/11...
#NephJC
@kidneyboy.bsky.social and moi hand over the @nephjc.bsky.social reigns to @nephroseeker.medsky.social & @brianrifkin.bsky.social
www.nephjc.com/news/2025/11...
#NephJC
@kidneyboy.bsky.social and moi hand over the @nephjc.bsky.social reigns to @nephroseeker.medsky.social & @brianrifkin.bsky.social
Taking the reigns — NephJC
In April 2014, Swapnil and I launched NephJC—and within weeks we were overwhelmed by the sheer work of running a twice-monthly, Twitter-based journal club. Fortunately, we also had a deep bench of fri...
www.nephjc.com
November 26, 2025 at 3:16 AM
It began in 2021, wondering why anyone would pick me for #NSMC. I applied in '22 and was surprised to be accepted. I’ve grown thanks to many of you (@hswapnil.medsky.social @kidneyboy.bsky.social ), though I still feel like a newcomer 😊
🙏 Grateful to be in this with @brianrifkin.bsky.social #NephJC
🙏 Grateful to be in this with @brianrifkin.bsky.social #NephJC
Reposted by Izabela Zakrocka
An announcement
www.nephjc.com/news/2025/11...
#NephJC
@kidneyboy.bsky.social and moi hand over the @nephjc.bsky.social reigns to @nephroseeker.medsky.social & @brianrifkin.bsky.social
www.nephjc.com/news/2025/11...
#NephJC
@kidneyboy.bsky.social and moi hand over the @nephjc.bsky.social reigns to @nephroseeker.medsky.social & @brianrifkin.bsky.social
Taking the reigns — NephJC
In April 2014, Swapnil and I launched NephJC—and within weeks we were overwhelmed by the sheer work of running a twice-monthly, Twitter-based journal club. Fortunately, we also had a deep bench of fri...
www.nephjc.com
November 25, 2025 at 12:03 PM
An announcement
www.nephjc.com/news/2025/11...
#NephJC
@kidneyboy.bsky.social and moi hand over the @nephjc.bsky.social reigns to @nephroseeker.medsky.social & @brianrifkin.bsky.social
www.nephjc.com/news/2025/11...
#NephJC
@kidneyboy.bsky.social and moi hand over the @nephjc.bsky.social reigns to @nephroseeker.medsky.social & @brianrifkin.bsky.social
Reposted by Izabela Zakrocka
Another interesting @kidneyint.bsky.social cohort study
www.kidney-international.org/article/S008...
Infection risk in kidney disease - lupus > ANCA, perhaps as ANCA is one and done (usually) whereas #lupus is never done?
Lupus > other primary and ADPKD is not surprising
#NephSky
www.kidney-international.org/article/S008...
Infection risk in kidney disease - lupus > ANCA, perhaps as ANCA is one and done (usually) whereas #lupus is never done?
Lupus > other primary and ADPKD is not surprising
#NephSky
November 23, 2025 at 1:53 PM
Another interesting @kidneyint.bsky.social cohort study
www.kidney-international.org/article/S008...
Infection risk in kidney disease - lupus > ANCA, perhaps as ANCA is one and done (usually) whereas #lupus is never done?
Lupus > other primary and ADPKD is not surprising
#NephSky
www.kidney-international.org/article/S008...
Infection risk in kidney disease - lupus > ANCA, perhaps as ANCA is one and done (usually) whereas #lupus is never done?
Lupus > other primary and ADPKD is not surprising
#NephSky
Reposted by Izabela Zakrocka
BK nephropathy
Clues:
- Heavy but focal tubulointerstitial inflammation
- Increased plasma cells
- Viral cytopathic change
- Features of CNI toxicity ->over immunosuppression (isometric vacuolization shown here)
-SV40 IHC confirmatory
#renalpath #pathsky #nephsky
Clues:
- Heavy but focal tubulointerstitial inflammation
- Increased plasma cells
- Viral cytopathic change
- Features of CNI toxicity ->over immunosuppression (isometric vacuolization shown here)
-SV40 IHC confirmatory
#renalpath #pathsky #nephsky
November 19, 2025 at 3:35 PM
BK nephropathy
Clues:
- Heavy but focal tubulointerstitial inflammation
- Increased plasma cells
- Viral cytopathic change
- Features of CNI toxicity ->over immunosuppression (isometric vacuolization shown here)
-SV40 IHC confirmatory
#renalpath #pathsky #nephsky
Clues:
- Heavy but focal tubulointerstitial inflammation
- Increased plasma cells
- Viral cytopathic change
- Features of CNI toxicity ->over immunosuppression (isometric vacuolization shown here)
-SV40 IHC confirmatory
#renalpath #pathsky #nephsky
Reposted by Izabela Zakrocka
Urine crystals in a patient with Crohn’s
Answer: www.kidney-international.org/article/S008... in @kidneyint.bsky.social
#NephSky
Answer: www.kidney-international.org/article/S008... in @kidneyint.bsky.social
#NephSky
November 19, 2025 at 5:40 PM
Urine crystals in a patient with Crohn’s
Answer: www.kidney-international.org/article/S008... in @kidneyint.bsky.social
#NephSky
Answer: www.kidney-international.org/article/S008... in @kidneyint.bsky.social
#NephSky
Reposted by Izabela Zakrocka
In the last #KidneyKompass @brendonneuen.bsky.social chats with Sophia Zoungas podcasts.apple.com/ca/podcast/k... on the SURPASS data
G-force FTW @christosargyrop.bsky.social @rnflex.bsky.social
Hey @brianrifkin.bsky.social if sema is captopril what would you call dulaglutide? 😏
G-force FTW @christosargyrop.bsky.social @rnflex.bsky.social
Hey @brianrifkin.bsky.social if sema is captopril what would you call dulaglutide? 😏
Understanding Renal Outcomes in SURPASS-CVOT, With Sophia Zoungas, MBBS, PhD
Podcast Episode · Kidney Compass: Navigating Clinical Trials · 2025-11-13 · 17m
podcasts.apple.com
November 19, 2025 at 2:58 PM
In the last #KidneyKompass @brendonneuen.bsky.social chats with Sophia Zoungas podcasts.apple.com/ca/podcast/k... on the SURPASS data
G-force FTW @christosargyrop.bsky.social @rnflex.bsky.social
Hey @brianrifkin.bsky.social if sema is captopril what would you call dulaglutide? 😏
G-force FTW @christosargyrop.bsky.social @rnflex.bsky.social
Hey @brianrifkin.bsky.social if sema is captopril what would you call dulaglutide? 😏
Reposted by Izabela Zakrocka
Should nephrologists further implement genetic testing in patients with CKD? In this #ASNJASN study of adult CKD management, genetic testing showed diagnostic and clinical utility in the year following the reporting of test results. Read more: kidney.pub/JASN0913
November 15, 2025 at 6:00 PM
Should nephrologists further implement genetic testing in patients with CKD? In this #ASNJASN study of adult CKD management, genetic testing showed diagnostic and clinical utility in the year following the reporting of test results. Read more: kidney.pub/JASN0913
Reposted by Izabela Zakrocka
Sharing our preprint - Multidisciplinary approach w/ biobank/EHR data, functional testing, genetic testing lab collaborations to reclassify 20 VUS in Alport syndrome, pkd. @amoralescgc.bsky.social @jeffminerphd.bsky.social www.medrxiv.org/content/10.1...
Leveraging genomic biobanks to enhance genetic testing outcomes for kidney disease
Chronic kidney disease (CKD) affects 9.1% globally and is associated with significant morbidity and mortality. While up to 10% of CKD cases yield a genetic diagnosis with hundreds of implicated genes ...
www.medrxiv.org
November 14, 2025 at 2:54 AM
Sharing our preprint - Multidisciplinary approach w/ biobank/EHR data, functional testing, genetic testing lab collaborations to reclassify 20 VUS in Alport syndrome, pkd. @amoralescgc.bsky.social @jeffminerphd.bsky.social www.medrxiv.org/content/10.1...
Reposted by Izabela Zakrocka
Great collaboration! So happy that our O'Brien Kidney Center Variant Validation Core could help out with the VUS analyses. @washunephrology.bsky.social @obrienkidney.bsky.social
Sharing our preprint - Multidisciplinary approach w/ biobank/EHR data, functional testing, genetic testing lab collaborations to reclassify 20 VUS in Alport syndrome, pkd. @amoralescgc.bsky.social @jeffminerphd.bsky.social www.medrxiv.org/content/10.1...
Leveraging genomic biobanks to enhance genetic testing outcomes for kidney disease
Chronic kidney disease (CKD) affects 9.1% globally and is associated with significant morbidity and mortality. While up to 10% of CKD cases yield a genetic diagnosis with hundreds of implicated genes ...
www.medrxiv.org
November 14, 2025 at 4:33 PM
Great collaboration! So happy that our O'Brien Kidney Center Variant Validation Core could help out with the VUS analyses. @washunephrology.bsky.social @obrienkidney.bsky.social
Reposted by Izabela Zakrocka
How'd I miss this one? Phase 1b results for mezagitamab, an anti-CD38 monoclonal antibody. (All meds should come with a pronunciation guide.) #NephSky #KidneyWk #IgAN #IgANephropathy
Mezagitamab Stablized eGFR 18 Months After Treatment in IgAN
Phase 1b IgAN data: mezagitamab (TAK‑079) stabilized eGFR, reduced proteinuria and serum Gd-IgA1, no serious AEs through Week 96; Phase 3 trials enrolling.
www.takeda.com
November 11, 2025 at 3:25 PM
How'd I miss this one? Phase 1b results for mezagitamab, an anti-CD38 monoclonal antibody. (All meds should come with a pronunciation guide.) #NephSky #KidneyWk #IgAN #IgANephropathy
Reposted by Izabela Zakrocka
Late breakers that included children:
✅Setanaxib in Alport (12+)
Late breakers that did NOT include children:
🚫Atacicept in IgAN
🚫CONFIDENCE
🚫PISCES: Fish oil in Dialysis
🚫LIBERATE-D
🚫balcinrenone + dapa
🚫Obintuzumab in lupus nephritis
🚫Sibeprenlimab in IgA
🚫MIL62 in membranous
+more
#KidneyWk
✅Setanaxib in Alport (12+)
Late breakers that did NOT include children:
🚫Atacicept in IgAN
🚫CONFIDENCE
🚫PISCES: Fish oil in Dialysis
🚫LIBERATE-D
🚫balcinrenone + dapa
🚫Obintuzumab in lupus nephritis
🚫Sibeprenlimab in IgA
🚫MIL62 in membranous
+more
#KidneyWk
November 8, 2025 at 8:27 PM
Late breakers that included children:
✅Setanaxib in Alport (12+)
Late breakers that did NOT include children:
🚫Atacicept in IgAN
🚫CONFIDENCE
🚫PISCES: Fish oil in Dialysis
🚫LIBERATE-D
🚫balcinrenone + dapa
🚫Obintuzumab in lupus nephritis
🚫Sibeprenlimab in IgA
🚫MIL62 in membranous
+more
#KidneyWk
✅Setanaxib in Alport (12+)
Late breakers that did NOT include children:
🚫Atacicept in IgAN
🚫CONFIDENCE
🚫PISCES: Fish oil in Dialysis
🚫LIBERATE-D
🚫balcinrenone + dapa
🚫Obintuzumab in lupus nephritis
🚫Sibeprenlimab in IgA
🚫MIL62 in membranous
+more
#KidneyWk