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GcL

@grosscol.bsky.social

110 followers 81 following 61 posts

Programming and human genetics. Working with TOPMED data and providing a view into human variation via BRAVO (bravo.sph.umich.edu)

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GcL @grosscol.bsky.social · 1d

As always, your taste in eyewear is excellent.

GcL @grosscol.bsky.social · 5d

That's a heck of a Lego endeavor! Impressive is an understatement.

GcL @grosscol.bsky.social · 7d

Reminds me of a project that had to satisfy a requirement of a contact specifying the solution needed to use machine learning.

We found a linear regression model that worked well enough, and made sure we never clarified beyond "supervised machine learning implementation" in the docs.

GcL @grosscol.bsky.social · 9d

@katmabu.bsky.social keep it up. Good luck!

GcL @grosscol.bsky.social · 10d

@bcdreyer.social how do you edit copy? I thought paste took care of that?! /S

GcL @grosscol.bsky.social · 10d

Excellent. More great work of yours that I will unabashedly yoink for my own collaborative story telling with friends. Thank you.

GcL @grosscol.bsky.social · 10d

@@cherylrofer.bsky.social I came across a post of yours, checked your profile, and found that I liked both.

I have heard a lot about thorium reactors in recent years. What are your thoughts on thorium and thorium reactors?

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GcL @grosscol.bsky.social · 11d

Watched this yesterday in the background. While nodding along, the offhand comment that you've written a compiler in assembly got my full attention. That's one of the projects where curiosity and masochism share a border.

GcL @grosscol.bsky.social · 13d

Most people don't have the ability to point out the hallmarks of fascism. My go-to recommendation is en.m.wikipedia.org/wiki/How_Fas...

How Fascism Works - Wikipedia

en.m.wikipedia.org

GcL @grosscol.bsky.social · 13d

Most people don't have the ability to point out the hallmarks of fascism. My go-to recommendation is en.m.wikipedia.org/wiki/How_Fas...

How Fascism Works - Wikipedia

en.m.wikipedia.org

GcL @grosscol.bsky.social · 14d

Trimming the hedges around the base of the tent helps as well.

GcL @grosscol.bsky.social · 15d

Unfortunately for us on this side of the border, that is a safer and saner stance for you.

GcL @grosscol.bsky.social · 16d

Tipsy women lazing about in pubs handing out cubes is no basis for a system of government!

GcL @grosscol.bsky.social · 17d

*it was originally written in the 1970s
*It has a learning curve
*It is a command line interface

It's blazingly fast to execute and works even when the input has millions of lines.

GcL @grosscol.bsky.social · 18d

Had no clue who you or Heather were, but "commie podcast hags" sold me on following both of you immediately.

GcL @grosscol.bsky.social · 18d

Using an ai generated image for the design feels bad.

GcL @grosscol.bsky.social · 19d

This post reads like it was written by an LLM

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GcL @grosscol.bsky.social · 24d

Those that know history are done to watch everyone else repeat it.

Catherine Rampell @crampell.bsky.social · 24d

...

GcL @grosscol.bsky.social · 24d

Being able to hear the disk drive grinding and grumbling away as it reads the floppy disk is an important part of the authentic Oregon Trail experience. Also, where in the world is Carmen Sandeigo?

GcL @grosscol.bsky.social · 27d

Interesting read. I do enjoy surprises in sufficiently powered well conducted research as they often elucidate the presence of previously unknown mechanisms.

Regarding science reporting , I wish the article had direct citations for the studies and links to relevant publications.

GcL @grosscol.bsky.social · 28d

My desire to remain informed is at odds with my desire to remain sane.

GcL @grosscol.bsky.social · 29d

Your cutting edge comics are always on point.

GcL @grosscol.bsky.social · Sep 14

There's always a Pratchett quote.

Reposted by GcL

Michael Pollard @kmichaelpollard.bsky.social · Sep 13

If you want something written about the human genome that is not complex science, then this is a good place to start. 🧪

Photo of the cover of the book "The Mysterious World of the Human Genome" by Frank Ryan.

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GcL @grosscol.bsky.social · Sep 13

The keyword is breakdown. The meal worms breakdown a substantial amount of the ingested styrofoam.