Reposted by Miguel Soares
@EMBO Practical Course
Pipetting scRNA-seq data into computational cells
18 – 23 May 2026 | Oeiras/Lisbon, Portugal @gimmfoundation.bsky.social
Registration open!
Pipetting scRNA-seq data into computational cells
18 – 23 May 2026 | Oeiras/Lisbon, Portugal @gimmfoundation.bsky.social
Registration open!
Pipetting scRNA-seq data into computational cells
Single-cell transcriptomics is transforming biology, uncovering hidden cell states, dynamic transitions, and intricate interactions across systems from immunity to cancer. Yet as these technologies s…
meetings.embo.org
November 23, 2025 at 11:37 AM
@EMBO Practical Course
Pipetting scRNA-seq data into computational cells
18 – 23 May 2026 | Oeiras/Lisbon, Portugal @gimmfoundation.bsky.social
Registration open!
Pipetting scRNA-seq data into computational cells
18 – 23 May 2026 | Oeiras/Lisbon, Portugal @gimmfoundation.bsky.social
Registration open!
Reposted by Miguel Soares
Homeostatic control of energy metabolism by monocyte-derived macrophages
@elmiguelche.bsky.social and colleagues show that macrophages sense dysregulated iron metabolism in parenchymal cells and respond by sustaining mitochondrial function in affected cells
www.embopress.org/doi/full/10....
@elmiguelche.bsky.social and colleagues show that macrophages sense dysregulated iron metabolism in parenchymal cells and respond by sustaining mitochondrial function in affected cells
www.embopress.org/doi/full/10....
November 19, 2025 at 3:20 PM
Homeostatic control of energy metabolism by monocyte-derived macrophages
@elmiguelche.bsky.social and colleagues show that macrophages sense dysregulated iron metabolism in parenchymal cells and respond by sustaining mitochondrial function in affected cells
www.embopress.org/doi/full/10....
@elmiguelche.bsky.social and colleagues show that macrophages sense dysregulated iron metabolism in parenchymal cells and respond by sustaining mitochondrial function in affected cells
www.embopress.org/doi/full/10....
🧵 Thrilled to share our new work in @embojournal! Over a century after Metchnikoff recognized macrophages as central to organismal homeostasis, we reveal how they act as metabolic guardians through an unexpected mechanism.
www.embopress.org/doi/full/10....
(1/9)
www.embopress.org/doi/full/10....
(1/9)
Homeostatic control of energy metabolism by monocyte-derived macrophages | The EMBO Journal
imageimageMacrophages play critical roles in the homeostatic control systems that maintain vital
parameters within physiological ranges. This study characterizes how mouse monocyte-derived
macrophages...
www.embopress.org
November 19, 2025 at 2:11 PM
🧵 Thrilled to share our new work in @embojournal! Over a century after Metchnikoff recognized macrophages as central to organismal homeostasis, we reveal how they act as metabolic guardians through an unexpected mechanism.
www.embopress.org/doi/full/10....
(1/9)
www.embopress.org/doi/full/10....
(1/9)
Reposted by Miguel Soares
of the influenza vaccine is low (against infection). What is forgotten is the protection from non-communicable diseases.
What if you could reduce your risk to heart disease by 40%?
What is you could reduce you risk to dementia by at least 10%?
That is what vaccines do!
3/10
What if you could reduce your risk to heart disease by 40%?
What is you could reduce you risk to dementia by at least 10%?
That is what vaccines do!
3/10
September 19, 2025 at 2:15 PM
of the influenza vaccine is low (against infection). What is forgotten is the protection from non-communicable diseases.
What if you could reduce your risk to heart disease by 40%?
What is you could reduce you risk to dementia by at least 10%?
That is what vaccines do!
3/10
What if you could reduce your risk to heart disease by 40%?
What is you could reduce you risk to dementia by at least 10%?
That is what vaccines do!
3/10
Food for thought from:
@lferreiramoita.bsky.social in JCI - Biological and clinical implications of a model of surveillance immunity www.jci.org/articles/vie...
@lferreiramoita.bsky.social in JCI - Biological and clinical implications of a model of surveillance immunity www.jci.org/articles/vie...
JCI -
Biological and clinical implications of a model of surveillance immunity
www.jci.org
August 5, 2025 at 9:37 AM
Food for thought from:
@lferreiramoita.bsky.social in JCI - Biological and clinical implications of a model of surveillance immunity www.jci.org/articles/vie...
@lferreiramoita.bsky.social in JCI - Biological and clinical implications of a model of surveillance immunity www.jci.org/articles/vie...
Reposted by Miguel Soares
Beautiful new work from Maz Divangahi lab about the enhanced anti-tumoral activity of β-glucan + BCG trained neutrophils leading to tumor eradication.
#freshoffthepress @cp-immunity.bsky.social
#freshoffthepress @cp-immunity.bsky.social
Combining BCG with β-glucan reprograms granulopoiesis to generate trained neutrophils with enhanced antitumoral activity, preventing their protumoral conversion and leading to complete tumor eradication @cp-immunity.bsky.social www.cell.com/immunity/ful...
June 23, 2025 at 9:57 PM
Beautiful new work from Maz Divangahi lab about the enhanced anti-tumoral activity of β-glucan + BCG trained neutrophils leading to tumor eradication.
#freshoffthepress @cp-immunity.bsky.social
#freshoffthepress @cp-immunity.bsky.social
Reposted by Miguel Soares
A recent study based on observations in humans and experiments in mice proposes that induction of bilirubin production in response to Plasmodium spp. infection is an evolutionary conserved mechanism against malaria. 🧪 www.science.org/doi/10.1126/...
June 20, 2025 at 3:30 PM
A recent study based on observations in humans and experiments in mice proposes that induction of bilirubin production in response to Plasmodium spp. infection is an evolutionary conserved mechanism against malaria. 🧪 www.science.org/doi/10.1126/...
Reposted by Miguel Soares
Rewring lipid metabolism to sustain thermoregulation during sepsis. Don’t let it get cold! A very interesting piece from Miguel Soares lab @elmiguelche.bsky.social @gimmfoundation.bsky.social
A bioenergetic basis for multiorgan dysfunction in sepsis https://www.biorxiv.org/content/10.1101/2025.06.12.659280v1
June 18, 2025 at 8:34 AM
Rewring lipid metabolism to sustain thermoregulation during sepsis. Don’t let it get cold! A very interesting piece from Miguel Soares lab @elmiguelche.bsky.social @gimmfoundation.bsky.social
Reposted by Miguel Soares
The future of heart health: AI, immunity, and personalized prevention | Science | AAAS www.science.org/content/webi...
The future of heart health: AI, immunity, and personalized prevention
www.science.org
June 20, 2025 at 7:49 PM
The future of heart health: AI, immunity, and personalized prevention | Science | AAAS www.science.org/content/webi...
Reposted by Miguel Soares
Call for our new PhD program is open. Come join one of our labs at Gulbenkian Institute for Molecular Medicine - Lisbon-Oeiras, Portugal. Help us spread the word
Exciting opportunities are now available!
GIMM offers a distinctive PhD Program designed to attract & cultivate highly skilled researchers in biology & biomedicine.
Deadline: July 9
👉 Apply now! gimm.pt/education-and-training/phd-program/
GIMM offers a distinctive PhD Program designed to attract & cultivate highly skilled researchers in biology & biomedicine.
Deadline: July 9
👉 Apply now! gimm.pt/education-and-training/phd-program/
June 17, 2025 at 7:03 PM
Call for our new PhD program is open. Come join one of our labs at Gulbenkian Institute for Molecular Medicine - Lisbon-Oeiras, Portugal. Help us spread the word
Reposted by Miguel Soares
A bioenergetic basis for multiorgan dysfunction in sepsis https://www.biorxiv.org/content/10.1101/2025.06.12.659280v1
June 17, 2025 at 9:00 PM
A bioenergetic basis for multiorgan dysfunction in sepsis https://www.biorxiv.org/content/10.1101/2025.06.12.659280v1
Reposted by Miguel Soares
Check out the paper from our latest collaboration with Miguel Soares's lab:
🦠A metabolite-based resistance mechanism against malaria
Now out in Science: www.science.org/doi/10.1126/...
@gimmfoundation.bsky.social @turkubioscience.bsky.social @inflames-flagship.bsky.social @utu.fi
🦠A metabolite-based resistance mechanism against malaria
Now out in Science: www.science.org/doi/10.1126/...
@gimmfoundation.bsky.social @turkubioscience.bsky.social @inflames-flagship.bsky.social @utu.fi
Turun biotiedekeskuksen tutkijat olivat mukana kansainvälisessä tutkimuksessa, jossa löydettiin uusi puolustuskeino malariaa vastaan.
Tutkimuksessa kävi ilmi, että keltaisuus toimii elimistön luonnollisena suojamekanismina malarialoisen aiheuttamaa infektiota vastaan.
www.utu.fi/fi/ajankohta...
Tutkimuksessa kävi ilmi, että keltaisuus toimii elimistön luonnollisena suojamekanismina malarialoisen aiheuttamaa infektiota vastaan.
www.utu.fi/fi/ajankohta...
Tutkijat löysivät uuden puolustuskeinon malariaa vastaan – keltaisuus toimii elimistön luonnollisena suojamekanismina
Turun yliopiston biotiedekeskuksen tutkijat ovat olleet mukana merkittävässä kansainvälisessä tutkimuksessa, joka paljasti keltaisuuden uudenlaisen roolin elimistön luonnollisena puolustuskeinona m
www.utu.fi
June 13, 2025 at 8:40 AM
Check out the paper from our latest collaboration with Miguel Soares's lab:
🦠A metabolite-based resistance mechanism against malaria
Now out in Science: www.science.org/doi/10.1126/...
@gimmfoundation.bsky.social @turkubioscience.bsky.social @inflames-flagship.bsky.social @utu.fi
🦠A metabolite-based resistance mechanism against malaria
Now out in Science: www.science.org/doi/10.1126/...
@gimmfoundation.bsky.social @turkubioscience.bsky.social @inflames-flagship.bsky.social @utu.fi
A metabolite-based resistance mechanism against malaria | Science www.science.org/doi/10.1126/...
@gimmfoundation.bsky.social
@gimmfoundation.bsky.social
A metabolite-based resistance mechanism against malaria
Jaundice is a common presentation of Plasmodium falciparum malaria, which arises from the accumulation of circulating bilirubin. It is not understood whether it represents an adaptive or maladaptive r...
www.science.org
June 12, 2025 at 6:35 PM
A metabolite-based resistance mechanism against malaria | Science www.science.org/doi/10.1126/...
@gimmfoundation.bsky.social
@gimmfoundation.bsky.social
There is a price tag for everything…..
www.sciencedirect.com/science/arti... Evolutionary medicine in action: Sickle hemoglobin fuels tumor progression - ScienceDirect
www.sciencedirect.com/science/arti... Evolutionary medicine in action: Sickle hemoglobin fuels tumor progression - ScienceDirect
June 10, 2025 at 4:04 PM
There is a price tag for everything…..
www.sciencedirect.com/science/arti... Evolutionary medicine in action: Sickle hemoglobin fuels tumor progression - ScienceDirect
www.sciencedirect.com/science/arti... Evolutionary medicine in action: Sickle hemoglobin fuels tumor progression - ScienceDirect
Reposted by Miguel Soares
Latest from the Nature Podcast 🔊 Male mice can grow female organs — if their mothers lack iron
https://go.nature.com/3SY8I2V
https://go.nature.com/3SY8I2V
Male mice can grow female organs — if their mothers lack iron
Nature - Hear the biggest stories from the world of science | 04 June 2025
go.nature.com
June 8, 2025 at 9:03 AM
Latest from the Nature Podcast 🔊 Male mice can grow female organs — if their mothers lack iron
https://go.nature.com/3SY8I2V
https://go.nature.com/3SY8I2V
Reposted by Miguel Soares
🚨Great new MSc and PhD positions available @gimmfoundation!
Check out the links or use the QR code.
MSc:
www.medicina.ulisboa...
PhD:
gimm.pt/course/phd-p...
Check out the links or use the QR code.
MSc:
www.medicina.ulisboa...
PhD:
gimm.pt/course/phd-p...
June 3, 2025 at 3:18 PM
🚨Great new MSc and PhD positions available @gimmfoundation!
Check out the links or use the QR code.
MSc:
www.medicina.ulisboa...
PhD:
gimm.pt/course/phd-p...
Check out the links or use the QR code.
MSc:
www.medicina.ulisboa...
PhD:
gimm.pt/course/phd-p...
Reposted by Miguel Soares
Curious about aging & longevity research? Join us at GIMM Fest (Lisbon, Portugal)
Discover groundbreaking insights & engage with top researchers. It's a celebration of curiosity & a catalyst for change.
🗓️ Sept 4-5: Scientific Sessions + Sept 6: Public Event
👉 gimm.pt/gimm-festival/
Discover groundbreaking insights & engage with top researchers. It's a celebration of curiosity & a catalyst for change.
🗓️ Sept 4-5: Scientific Sessions + Sept 6: Public Event
👉 gimm.pt/gimm-festival/
May 19, 2025 at 9:32 AM
Curious about aging & longevity research? Join us at GIMM Fest (Lisbon, Portugal)
Discover groundbreaking insights & engage with top researchers. It's a celebration of curiosity & a catalyst for change.
🗓️ Sept 4-5: Scientific Sessions + Sept 6: Public Event
👉 gimm.pt/gimm-festival/
Discover groundbreaking insights & engage with top researchers. It's a celebration of curiosity & a catalyst for change.
🗓️ Sept 4-5: Scientific Sessions + Sept 6: Public Event
👉 gimm.pt/gimm-festival/
Reposted by Miguel Soares
@cleeterichter.bsky.social & Kelsey Voss discuss a study from @elmiguelche.bsky.social that highlights a role for monocyte-derived macrophages in iron homeostasis and its control of systemic energy metabolism
Monocytes rule energy metabolism with an iron fist - Nature Reviews Immunology
A preprint by Martins, Blankehaus et al. highlights an important role for monocyte-derived macrophages in iron homeostasis and its control of systemic energy metabolism.
www.nature.com
April 23, 2025 at 3:21 PM
@cleeterichter.bsky.social & Kelsey Voss discuss a study from @elmiguelche.bsky.social that highlights a role for monocyte-derived macrophages in iron homeostasis and its control of systemic energy metabolism
Red blood cells undergo lytic programmed cell death involving NLRP3: Cell www.cell.com/cell/fulltex...
Red blood cells undergo lytic programmed cell death involving NLRP3
Complement exposure induces programmed cell death of red blood cells due to the intracellular
activation of miniNLRP3 and caspase-8. Inhibiting NLRP3 signaling reduces cytoskeletal
damage and prevents...
www.cell.com
April 22, 2025 at 6:51 AM
Red blood cells undergo lytic programmed cell death involving NLRP3: Cell www.cell.com/cell/fulltex...
Reposted by Miguel Soares
Is it still not clear?
Abusing the state to force your ideology on others.
Fascism, Fascism, Fascism. There is no other term for this.
Jay Bhattacharya? 🤡🤡🤡 a useful idiot.
Abusing the state to force your ideology on others.
Fascism, Fascism, Fascism. There is no other term for this.
Jay Bhattacharya? 🤡🤡🤡 a useful idiot.
After freezing all grants to Columbia University last week, the National Institutes of Health is now stopping grant and contract payments to Harvard University and four other universities. scim.ag/4ikYp2T
NIH freezes funds to Harvard and four other universities, but can’t tell them
Move follows broader White House attack on Harvard funding and stop-work orders to contractors
scim.ag
April 18, 2025 at 9:32 PM
Is it still not clear?
Abusing the state to force your ideology on others.
Fascism, Fascism, Fascism. There is no other term for this.
Jay Bhattacharya? 🤡🤡🤡 a useful idiot.
Abusing the state to force your ideology on others.
Fascism, Fascism, Fascism. There is no other term for this.
Jay Bhattacharya? 🤡🤡🤡 a useful idiot.
More good news:
MEP Christian Ehler's ITRE report adopted by the European Parliament: strong support for an expanded and independent ERC.
Happy with the proposal of €220 billion for the EU's next research framework programme! Thank you!
Press briefing
multimedia.europarl.europa.eu/en/webstream...
MEP Christian Ehler's ITRE report adopted by the European Parliament: strong support for an expanded and independent ERC.
Happy with the proposal of €220 billion for the EU's next research framework programme! Thank you!
Press briefing
multimedia.europarl.europa.eu/en/webstream...
Press conference by Christian EHLER (EPP, DE) rapporteur, on the implementation of the Horizon Europe programme - Multimedia Centre
The multimedia platform of the European Parliament is the official public available repository of the media production of the Secretariat of the European Parliament, managed by the Directorate-General...
multimedia.europarl.europa.eu
April 10, 2025 at 2:03 PM
Important definitions and concepts to understand that what is happening in many countries is not new.
Fascism: Why Understanding the Past is Critical for the Present - Department of French, Hispanic and Italian Studies
Dr. Carlo Testa explains why understanding historical Fascism is critical to resisting the many forms of Fascism that are arising today.
fhis.ubc.ca
March 29, 2025 at 2:45 PM
Important definitions and concepts to understand that what is happening in many countries is not new.