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Ran Blekhman @blekhman.bsky.social · Jun 18

Another review from my lab out this week, on analyzing gut microbiome data from global populations -- tackling computational challenges and providing practical frameworks and resources for the field

With Sabrina Arif, @richabdill.com, @samanthagraham.bsky.social

www.cell.com/trends/micro...

Analyzing human gut microbiome data from global populations: challenges and resources

Research on the human gut microbiome is expanding rapidly; yet, most published studies focus on populations from high-income regions such as North America and Europe. Underrepresentation of population...

www.cell.com

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Cell Host & Microbe @cp-cellhostmicrobe.bsky.social · Jun 11

Metabolic ecology of microbiomes: Nutrient competition, host benefits, and community engineering

Review by Erik Bakkeren, Vit Piskovsky, and Kevin R. Foster
www.cell.com/cell-host-mi...

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United European Gastroenterology @myueg.bsky.social · May 3

📈With obesity and overweight expected to affect 50% of the global population by 2035, the need for change has never been clearer. Join experts on 5 June at #EUParliament for an in-depth discussion on tackling this growing health crisis. Register now: https://bit.ly/3EIlu1H

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John Lukens @lukensjohnr.bsky.social · May 3

Excited to share our new work demonstrating a role for astrocytic inflammasome signaling in modulating hippocampal plasticity. @cp-immunity.bsky.social
All credit to Kristine Zengeler, who was the brains🧠 and muscle💪 behind this project and is a wonderful collaborator. www.cell.com/immunity/ful...

Inflammasome signaling in astrocytes modulates hippocampal plasticity

The function of immune pathways in homeostatic neurobiology remains underexplored. Zengeler et al. find that the inflammasome complex, typically associated with immune responses, is involved in memory...

www.cell.com

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Chen Ran @chenran.bsky.social · Apr 16

Lots of recent papers discuss the nucleus of the solitary tract in interoception. In this review, we take a sensory processing perspective on how interoceptive signals are encoded in the NTS:
www.sciencedirect.com/science/arti...

Interoceptive processing in the nucleus of the solitary tract

The interoceptive nervous system continuously monitors the status of visceral organs to synthesize internal perceptions and regulate behavioral and ph…

www.sciencedirect.com

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Marcus Böhme @boehmemarcus.bsky.social · Apr 12

www.nature.com/articles/s41...

Stress dynamically modulates neuronal autophagy to gate depression onset - Nature

Acute stress activates autophagy in the lateral habenula, whereas chronic stress suppresses it, with this autophagy having a causal role in maintaining emotional homeostasis against stress, and its re...

www.nature.com

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Nature Metabolism @natmetabolism.nature.com · Apr 9

NEWS&VIEWS | LO Dragsted, @hroager.bsky.social , @catalinacuparencu.bsky.social (U Copenhagen):

A methodology for assessing dietary intake using stool metagenomes to detect food DNA🧬💩

https://bit.ly/4lfJ1aK ?utm_source=bluesky&utm_medium=social&utm_campaign=natmetab

Querying stool for dietary information - Nature Metabolism

Accurately determining food intake remains a substantial challenge in nutrition research. This issue of Nature Metabolism introduces a methodology for assessing dietary intake, using stool metagenomic data to detect food DNA from a broad range of foods.

bit.ly

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Kevin Mitchell @wiringthebrain.bsky.social · Apr 10

A map of neural signals and circuits traces the logic of brain computation www.nature.com/articles/d41...

A map of neural signals and circuits traces the logic of brain computation

A large consortium of scientists adds functional data to neuronal wiring maps, seeking to crack the computational circuitry of the mouse brain.

www.nature.com

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John Lukens @lukensjohnr.bsky.social · Apr 7

Inflammatory and anti-inflammatory cytokines bidirectionally modulate amygdala circuits regulating anxiety: @cellpress.bsky.social www.cell.com/cell/fulltex...

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Eric Topol @erictopol.bsky.social · Apr 7

In people with diabetes, GLP-1 and SGLT2i drugs were associated with less Alzheimer's disease and related dementias
jamanetwork.com/journals/jam...

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Marcus Böhme @boehmemarcus.bsky.social · Apr 6

I am excited to share our latest publication where we investigated the impact of a #Bifidobacterium longum strain on #perinatal anxiety and depressive symptoms

#mood #stress #postpartum #gutbrainaxis

www.nature.com/articles/s41...

The impact of ingestion of Bifidobacterium longum NCC3001 on perinatal anxiety and depressive symptoms: a randomized controlled trial - Scientific Reports

Scientific Reports - The impact of ingestion of Bifidobacterium longum NCC3001 on perinatal anxiety and depressive symptoms: a randomized controlled trial

www.nature.com

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Eric Topol @erictopol.bsky.social · Apr 3

The gut microbiome's link with multiple sclerosis www.cell.com/cell-reports...

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Marcus Böhme @boehmemarcus.bsky.social · Apr 3

Congrats!

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Feargal Ryan @feargalr.bsky.social · Apr 2

Delighted our study (7+ years in the making) is out today in Nature. In a nutshell, 48 hours of antibiotics in week 1 led to impaired vaccine responses up to 15 months later in infants. We show (in-vivo) a probiotic can fix it #microbiome #science #immunology
www.nature.com/articles/s41...

Bifidobacteria support optimal infant vaccine responses - Nature

Neonatal antibiotic use is shown to reduce immune response to infant vaccines, accompanied by reduced abundance of Bifidobacteria in the gut microbiota, with experiments in mice indicating that probio...

www.nature.com

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thetranscendedman @atranscendedman.bsky.social · Apr 2

Singapore study of 184 women found that daily probiotic Bifidobacterium longum NCC3001 during late pregnancy and postpartum did not ease anxiety or depression symptoms.

Results varied widely, suggesting more research is needed.

www.nature.com/articles/s41...

The impact of ingestion of Bifidobacterium longum NCC3001 on perinatal anxiety and depressive symptoms: a randomized controlled trial - Scientific Reports

Scientific Reports - The impact of ingestion of Bifidobacterium longum NCC3001 on perinatal anxiety and depressive symptoms: a randomized controlled trial

www.nature.com

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Sean Gibbons 🦠💩 @gibbological.bsky.social · Mar 24

Curious about the gut microbiome & its impacts on sleep throughout the adult lifespan? 🦠😴

You're in luck! @isbscience.org PhD student Jacob Cavon led a review of this topic for the @amiposts.bsky.social journal Letters in Applied Microbiology (just accepted): academic.oup.com/lambio/advan...

The human gut microbiome and sleep across adulthood: associations and therapeutic potential

Abstract. Sleep is an essential homeostatic process that undergoes dynamic changes throughout the lifespan, with distinct life stages predisposed to specif

academic.oup.com

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Michael Wong @miquai.bsky.social · Mar 29

I received a heartbreaking email today: A paper in a special issue I’m editing is being retracted because one of its authors is afraid of losing their job and their legal status in the U.S. if they publish a scientific study on evolution. Yes, on evolution, nature's engine of diversity.

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Sergiu P. Pasca @sergiuppasca.bsky.social · Mar 14

In this week’s @nature.com, we publish a group effort to outline a framework for studies with neural #organoids, #assembloids and transplantation. More details below 1/n

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Marcus Böhme @boehmemarcus.bsky.social · Mar 14

No worries. Thank you so much

Marcus Böhme @boehmemarcus.bsky.social · Mar 6

Prohormone cleavage prediction uncovers a non-incretin anti-obesity peptide

www.nature.com/articles/s41...

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c0nc0rdance @c0nc0rdance.bsky.social · Feb 27

This administration is destroying US science.

"Foreign scientists hired under Title 42 have even more reason to worry... their visas require they leave the country within 60 days unless they obtain a new position. Many have put down roots, bought houses & have children in school."

TK (Takashi DY) Kozai @bioniclab.bsky.social · Feb 27

www.science.org/content/arti...

NIH ban on renewing senior scientists adds to assaults on its in-house research

Policy follows firings of tenure-track scientists and suspension of training programs

www.science.org

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Eric Topol @erictopol.bsky.social · Feb 25

What is your pace of aging? A new @nature.com feature on molecular clocks by gets into the issues surrounding these tests (can is really can't) nature.com/articles/d41... by @heidiledford.bsky.social

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Magdalena Skipper @magdalenaskipper.bsky.social · Feb 25

Great minds… within 24 hrs both us at @nature.com and @science.org make similar appeals to the research community. And @holdenthorp.bsky.social and I didn’t even exchange notes about it ;-)
🧪

www.nature.com/articles/d41...

www.science.org/doi/10.1126/...

Come together, right now

The chaos, conflicting information, firings, and hurtful rhetoric of the Trump administration’s approach to science over the past month are causing anxiety, grief, and concern for the scientific commu...

www.science.org

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Nature @nature.com · Feb 20

Almost all grant-review meetings under Trump 2.0 remain suspended at the US National Institutes of Health (NIH), preventing the world’s largest public funder of biomedical research from spending much of its US$47 billion annual budget.

https://go.nature.com/4gM6oW4

Revealed: NIH research grants still frozen despite lawsuits challenging Trump order

The Trump administration is exploiting a loophole to keep a funding freeze in place, leaving researchers in limbo.

go.nature.com

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Marcus Böhme @boehmemarcus.bsky.social · Feb 19

Congratulations Ben, Jatin and team!

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