TK (Takashi DY) Kozai
@bioniclab.bsky.social
Ernest E Roth Professor. Dept Bioengineering, University of Pittsburgh.
BionicLab.org
Neural Engineering; Neural Interfaces: Neurostimulation; Neurocomputation
BionicLab.org
Neural Engineering; Neural Interfaces: Neurostimulation; Neurocomputation
Pinned
Excited to be able to share our (Robert Gaunt, Alberto Vazquez, Omar Gharbawie, Mac Hooks, Chengcheng Huang) recent work to the University of Pittsburgh Provost and Vice Chancellor of Research, as well as the Board of Trustees.
news.engineering.pitt.edu/power-moves/
news.engineering.pitt.edu/power-moves/
Reposted by TK (Takashi DY) Kozai
The conference (agreement between House and Senate) appropriations bill that includes HHS and NIH was released this morning.
www.appropriations.senate.gov/news/majorit...
1/5
www.appropriations.senate.gov/news/majorit...
1/5
Committee Releases Conferenced Defense, Homeland Security, Labor, Health and Human Services, Education, and Related Agencies, and Transportation, Housing and Urban Development, and Related Agencies Bi...
United States Senate Committee on Appropriations
www.appropriations.senate.gov
January 20, 2026 at 3:55 PM
The conference (agreement between House and Senate) appropriations bill that includes HHS and NIH was released this morning.
www.appropriations.senate.gov/news/majorit...
1/5
www.appropriations.senate.gov/news/majorit...
1/5
Reposted by TK (Takashi DY) Kozai
NIH budget bill out today.
It’s the result of heavy negotiations in Congress over past month+. 🧪
Big pic: NIH budget now is abt more than funding. It’s abt restraining the technical ways NIH is being broken by Proj 2025. And the restraints in the bill are tepid 🤷♂️
Also: watch ICE/DHS budget.
🧵1/
It’s the result of heavy negotiations in Congress over past month+. 🧪
Big pic: NIH budget now is abt more than funding. It’s abt restraining the technical ways NIH is being broken by Proj 2025. And the restraints in the bill are tepid 🤷♂️
Also: watch ICE/DHS budget.
🧵1/
January 20, 2026 at 6:10 PM
NIH budget bill out today.
It’s the result of heavy negotiations in Congress over past month+. 🧪
Big pic: NIH budget now is abt more than funding. It’s abt restraining the technical ways NIH is being broken by Proj 2025. And the restraints in the bill are tepid 🤷♂️
Also: watch ICE/DHS budget.
🧵1/
It’s the result of heavy negotiations in Congress over past month+. 🧪
Big pic: NIH budget now is abt more than funding. It’s abt restraining the technical ways NIH is being broken by Proj 2025. And the restraints in the bill are tepid 🤷♂️
Also: watch ICE/DHS budget.
🧵1/
The Stockdale Paradox... not be confused with the Stockholm Syndrome.
a leadership principle where you maintain unwavering faith in eventual success ("never lose faith") while simultaneously confronting the brutal, harsh realities of your current situation ("never deny reality").
a leadership principle where you maintain unwavering faith in eventual success ("never lose faith") while simultaneously confronting the brutal, harsh realities of your current situation ("never deny reality").
One of the more common feedback observations I get from trainees subjected to my career presentations is thanks for being “frank” and “honest”. That was in the before times. Apparently everyone only presents trainees a rosy picture at odds with their experiences.
Another thing that I do to support my students is that I acknowledge what’s happening, and I don’t pretend that stuff like this is normal, and that everything’s fine.
I have had students tell me that they feel like they’re going crazy because they see what is happening but no one will speak of it.
I have had students tell me that they feel like they’re going crazy because they see what is happening but no one will speak of it.
January 19, 2026 at 9:55 PM
The Stockdale Paradox... not be confused with the Stockholm Syndrome.
a leadership principle where you maintain unwavering faith in eventual success ("never lose faith") while simultaneously confronting the brutal, harsh realities of your current situation ("never deny reality").
a leadership principle where you maintain unwavering faith in eventual success ("never lose faith") while simultaneously confronting the brutal, harsh realities of your current situation ("never deny reality").
Reposted by TK (Takashi DY) Kozai
The new NIH multi-year funding policy is a scheme to undercut the NIH budget and fund less science. And it’s working (see below). The Senate approps bill has language to limit MYF use, but the House version does not. Call your reps (House and Senate) and insist it’s included in the final bill! 🧪
Glad to see Congress doing some oversight of new NIH policies. www.congress.gov/crs-product/...
Number of new awards is way down since Trump took office, despite NIH spending the same amount of money.
Number of new awards is way down since Trump took office, despite NIH spending the same amount of money.
December 23, 2025 at 5:38 PM
The new NIH multi-year funding policy is a scheme to undercut the NIH budget and fund less science. And it’s working (see below). The Senate approps bill has language to limit MYF use, but the House version does not. Call your reps (House and Senate) and insist it’s included in the final bill! 🧪
Just out in @nature.com BME: Our Review unpacks intracortical microstimulation: axons, not somas, drive activation; direct + indirect pathways shape perception; parameters interact with neuron type, layer, and network; long-term use limited by neural depression & tissue response. 🧠⚡
rdcu.be/eZbTz
rdcu.be/eZbTz
Neural mechanisms underlying intracortical microstimulation for sensory restoration
Nature Biomedical Engineering - Intracortical microstimulation can elicit artificial sensations in persons who have lost sensation due to neurological injury or disease. This Review discusses...
rdcu.be
January 15, 2026 at 4:51 PM
Just out in @nature.com BME: Our Review unpacks intracortical microstimulation: axons, not somas, drive activation; direct + indirect pathways shape perception; parameters interact with neuron type, layer, and network; long-term use limited by neural depression & tissue response. 🧠⚡
rdcu.be/eZbTz
rdcu.be/eZbTz
Reposted by TK (Takashi DY) Kozai
A reminder as Congress finalizes NIH appropriations: the bill must limit multiyear funding (MYF), Vought's way of cutting the NIH budget without cutting the budget. MYF will devastate the research workforce.
@safa-science.bsky.social wrote this in July. Still relevant: substack.com/@scienceandf...
@safa-science.bsky.social wrote this in July. Still relevant: substack.com/@scienceandf...
A Quiet Policy Shift That Could Devastate American Science
Why NIH’s sudden move to multi-year grant funding should alarm every principal investigator and university
substack.com
January 14, 2026 at 4:33 AM
A reminder as Congress finalizes NIH appropriations: the bill must limit multiyear funding (MYF), Vought's way of cutting the NIH budget without cutting the budget. MYF will devastate the research workforce.
@safa-science.bsky.social wrote this in July. Still relevant: substack.com/@scienceandf...
@safa-science.bsky.social wrote this in July. Still relevant: substack.com/@scienceandf...
Reposted by TK (Takashi DY) Kozai
The appropriations bill that includes NIH is being finalized.
The Senate bill includes a bipartisan amendment from Senators Capito (WV) and Baldwin (WI) limiting multi-year funding of grants.
The House version does not and OMB has issued a veto threat if the House includes such language.
1/3
The Senate bill includes a bipartisan amendment from Senators Capito (WV) and Baldwin (WI) limiting multi-year funding of grants.
The House version does not and OMB has issued a veto threat if the House includes such language.
1/3
a close up of a brown surface with a few spots
ALT: a close up of a brown surface with a few spots
media.tenor.com
January 14, 2026 at 1:33 PM
The appropriations bill that includes NIH is being finalized.
The Senate bill includes a bipartisan amendment from Senators Capito (WV) and Baldwin (WI) limiting multi-year funding of grants.
The House version does not and OMB has issued a veto threat if the House includes such language.
1/3
The Senate bill includes a bipartisan amendment from Senators Capito (WV) and Baldwin (WI) limiting multi-year funding of grants.
The House version does not and OMB has issued a veto threat if the House includes such language.
1/3
🚨BREAKING ALERT: White House Poised to VETO Any NIH Budget Bill That Doesn't Torpedo U.S. Innovation! 🚨
#NIH #VetoThreat #USInnovation #ScienceFunding
#NIH #VetoThreat #USInnovation #ScienceFunding
January 14, 2026 at 1:29 PM
🚨BREAKING ALERT: White House Poised to VETO Any NIH Budget Bill That Doesn't Torpedo U.S. Innovation! 🚨
#NIH #VetoThreat #USInnovation #ScienceFunding
#NIH #VetoThreat #USInnovation #ScienceFunding
🇺🇸 America First patriots: We're $37T+ in debt & paying ~$970B/year in interest (13% of budget) at ~3.4% rates.NIH? Tiny <0.7% ($47-48B) fuels the innovation that makes foreigners buy our bonds, keeping rates low on US interest payments.
#NIH #TaxpayerValue #AmericanInnovation
#NIH #TaxpayerValue #AmericanInnovation
January 4, 2026 at 2:10 PM
🇺🇸 America First patriots: We're $37T+ in debt & paying ~$970B/year in interest (13% of budget) at ~3.4% rates.NIH? Tiny <0.7% ($47-48B) fuels the innovation that makes foreigners buy our bonds, keeping rates low on US interest payments.
#NIH #TaxpayerValue #AmericanInnovation
#NIH #TaxpayerValue #AmericanInnovation
💫 Apparently for the past 15-20 yrs, I’ve been quietly leveraging a super power: the ability to function on less sleep than most, adding >10,000 hrs, essentially giving several “bonus years” of deep work in my field of specialty: Neural engineering.
www.linkedin.com/posts/tkozai...
www.linkedin.com/posts/tkozai...
💫 I never thought of myself having a super power
🔬 Apparently for the past 15-20 years, I’ve been quietly leveraging a genetic one: the ability to function on less sleep than most people. Those… | TK...
💫 I never thought of myself having a super power
🔬 Apparently for the past 15-20 years, I’ve been quietly leveraging a genetic one: the ability to function on less sleep than most people. Those extra...
www.linkedin.com
January 2, 2026 at 3:05 PM
💫 Apparently for the past 15-20 yrs, I’ve been quietly leveraging a super power: the ability to function on less sleep than most, adding >10,000 hrs, essentially giving several “bonus years” of deep work in my field of specialty: Neural engineering.
www.linkedin.com/posts/tkozai...
www.linkedin.com/posts/tkozai...
DOGE in 2025:
Verified savings=~$10-25B. Taxpayers paid: $135-200B+ in short-term chaos.
Trillions long-term.
Experts: "Chaos to no avail."
Musk: "A little bit successful"... then walked away w/ 'Oops'
Net for taxpayers? Massive loss. www.linkedin.com/posts/tkozai... #Taxpayers #GovernmentWaste
Verified savings=~$10-25B. Taxpayers paid: $135-200B+ in short-term chaos.
Trillions long-term.
Experts: "Chaos to no avail."
Musk: "A little bit successful"... then walked away w/ 'Oops'
Net for taxpayers? Massive loss. www.linkedin.com/posts/tkozai... #Taxpayers #GovernmentWaste
‘They sowed chaos to no avail’: the lasting legacy of Elon Musk’s Doge | TK Kozai
🪚The DOGE Experiment: A costly experiment to taxpayers.
Elon Musk's Department of Government Efficiency (DOGE) promised bold fix for federal waste, folded in months. Claims started at $2T in savings ...
www.linkedin.com
January 1, 2026 at 5:51 PM
DOGE in 2025:
Verified savings=~$10-25B. Taxpayers paid: $135-200B+ in short-term chaos.
Trillions long-term.
Experts: "Chaos to no avail."
Musk: "A little bit successful"... then walked away w/ 'Oops'
Net for taxpayers? Massive loss. www.linkedin.com/posts/tkozai... #Taxpayers #GovernmentWaste
Verified savings=~$10-25B. Taxpayers paid: $135-200B+ in short-term chaos.
Trillions long-term.
Experts: "Chaos to no avail."
Musk: "A little bit successful"... then walked away w/ 'Oops'
Net for taxpayers? Massive loss. www.linkedin.com/posts/tkozai... #Taxpayers #GovernmentWaste
Reposted by TK (Takashi DY) Kozai
Caleb Watney of IFP talking about why academia and science sucks.
Broken record here, but we can’t have this discussion without talking about agendas and conflicts of interest.
IFP is funded by tech and rightwing billionaires who want to privatize science. 1/
Broken record here, but we can’t have this discussion without talking about agendas and conflicts of interest.
IFP is funded by tech and rightwing billionaires who want to privatize science. 1/
December 15, 2025 at 6:00 AM
Caleb Watney of IFP talking about why academia and science sucks.
Broken record here, but we can’t have this discussion without talking about agendas and conflicts of interest.
IFP is funded by tech and rightwing billionaires who want to privatize science. 1/
Broken record here, but we can’t have this discussion without talking about agendas and conflicts of interest.
IFP is funded by tech and rightwing billionaires who want to privatize science. 1/
🧠 From NIH-funded discovery → game-changing brain implants → NEW science that was impossible before.
This loop = cures, jobs & American tech leadership 🇺🇸
Join me MONDAY 12/8, 1pm ET:
"Next-Gen Neural Interfaces → Next Scientific Revolution”
🚀 #NeuroTech #BCI #NIH #BrainTech #TaxpayerWin
This loop = cures, jobs & American tech leadership 🇺🇸
Join me MONDAY 12/8, 1pm ET:
"Next-Gen Neural Interfaces → Next Scientific Revolution”
🚀 #NeuroTech #BCI #NIH #BrainTech #TaxpayerWin
December 6, 2025 at 2:12 PM
🧠 From NIH-funded discovery → game-changing brain implants → NEW science that was impossible before.
This loop = cures, jobs & American tech leadership 🇺🇸
Join me MONDAY 12/8, 1pm ET:
"Next-Gen Neural Interfaces → Next Scientific Revolution”
🚀 #NeuroTech #BCI #NIH #BrainTech #TaxpayerWin
This loop = cures, jobs & American tech leadership 🇺🇸
Join me MONDAY 12/8, 1pm ET:
"Next-Gen Neural Interfaces → Next Scientific Revolution”
🚀 #NeuroTech #BCI #NIH #BrainTech #TaxpayerWin
Reposted by TK (Takashi DY) Kozai
Is it worth rebutting this complaining mischaracterization of how NIH review works?
The peer review NIH does is incredibly valuable and constructive. Compare the NIH BRAIN initiative to the European Brain initiative — which added peer review after an open letter of serious complaints.
The peer review NIH does is incredibly valuable and constructive. Compare the NIH BRAIN initiative to the European Brain initiative — which added peer review after an open letter of serious complaints.
December 5, 2025 at 12:28 AM
Is it worth rebutting this complaining mischaracterization of how NIH review works?
The peer review NIH does is incredibly valuable and constructive. Compare the NIH BRAIN initiative to the European Brain initiative — which added peer review after an open letter of serious complaints.
The peer review NIH does is incredibly valuable and constructive. Compare the NIH BRAIN initiative to the European Brain initiative — which added peer review after an open letter of serious complaints.
📰 New paper from the University of Pittsburgh Neural Engineering Cross-Translation (UP NExT) program: our team mapped how micromotion-driven strain around Utah arrays predicts real world long-term performance in humans and NHPs. JNE 2025. #Pitt
November 23, 2025 at 3:26 PM
📰 New paper from the University of Pittsburgh Neural Engineering Cross-Translation (UP NExT) program: our team mapped how micromotion-driven strain around Utah arrays predicts real world long-term performance in humans and NHPs. JNE 2025. #Pitt
🇺🇲 Taxpayers fund research discussed at SfN 2025 & Bloodfest VI, advancing neurovascular & glial science, neural engineering, and next-gen brain tech. This work trains scientists, improves health outcomes, and keeps the U.S. #1 in biomedical innovation. #UPNExT #SfN25 #NeuralEngineering #UCSD
November 21, 2025 at 10:00 PM
🇺🇲 Taxpayers fund research discussed at SfN 2025 & Bloodfest VI, advancing neurovascular & glial science, neural engineering, and next-gen brain tech. This work trains scientists, improves health outcomes, and keeps the U.S. #1 in biomedical innovation. #UPNExT #SfN25 #NeuralEngineering #UCSD
Honored to be appointed the Ernest E. Roth Professor at Pitt. Grateful for the trainees, collaborators, and colleagues advancing neural engineering and glial biology. Thank you to the Dean for supporting our UP NExT vision, engineering fundamental neuroscience discovery to improve lives.
November 20, 2025 at 11:22 PM
Honored to be appointed the Ernest E. Roth Professor at Pitt. Grateful for the trainees, collaborators, and colleagues advancing neural engineering and glial biology. Thank you to the Dean for supporting our UP NExT vision, engineering fundamental neuroscience discovery to improve lives.
Check out University of Pittsburgh Neural Engineering Cross-Translation (UP NExT) program at #SfN25
Strong showing from @PittBioE’s UP NExT program at #SfN2025 in San Diego!
Trainees & faculty are advancing neural engineering across scales, from glial modulation & ICMS to neurovascular imaging & computational models.
See how Pitt is redefining neural engineering.
#Neurotech
Trainees & faculty are advancing neural engineering across scales, from glial modulation & ICMS to neurovascular imaging & computational models.
See how Pitt is redefining neural engineering.
#Neurotech
November 16, 2025 at 5:48 PM
Check out University of Pittsburgh Neural Engineering Cross-Translation (UP NExT) program at #SfN25
🚀 Discover cutting-edge neural engineering & glial biology at #SFN! Our lab (UP NExT) presents 8 posters linking neurons & non-neuronal cells to circuit stability & recovery using #electrophysiology, #TwoPhotonImaging, #microstimulation, #ultrasound #neuromodulation & single-cell transcriptomics.
November 15, 2025 at 4:05 PM
🚀 Discover cutting-edge neural engineering & glial biology at #SFN! Our lab (UP NExT) presents 8 posters linking neurons & non-neuronal cells to circuit stability & recovery using #electrophysiology, #TwoPhotonImaging, #microstimulation, #ultrasound #neuromodulation & single-cell transcriptomics.
NIH posted 14 executive leadership jobs with only 2-week windows.
SES roles normally stay open 30–45 days for real competition. Two weeks is far below standard practice and often signals a preselected candidate or rushed appointment.
Taxpayers deserve transparency. www.instagram.com/reel/DQ-xWIe...
SES roles normally stay open 30–45 days for real competition. Two weeks is far below standard practice and often signals a preselected candidate or rushed appointment.
Taxpayers deserve transparency. www.instagram.com/reel/DQ-xWIe...
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November 14, 2025 at 2:01 PM
NIH posted 14 executive leadership jobs with only 2-week windows.
SES roles normally stay open 30–45 days for real competition. Two weeks is far below standard practice and often signals a preselected candidate or rushed appointment.
Taxpayers deserve transparency. www.instagram.com/reel/DQ-xWIe...
SES roles normally stay open 30–45 days for real competition. Two weeks is far below standard practice and often signals a preselected candidate or rushed appointment.
Taxpayers deserve transparency. www.instagram.com/reel/DQ-xWIe...
New from University of Pittsburgh Neural Engineering Cross-Translation (UP NExT): PV interneurons don’t just control brain rhythms, they fine-tune blood flow too.
2P imaging + optogenetics, we found depth-specific vasoconstriction & dilation shaping both sensory-evoked & resting-state hemodynamics.
2P imaging + optogenetics, we found depth-specific vasoconstriction & dilation shaping both sensory-evoked & resting-state hemodynamics.
November 10, 2025 at 12:41 AM
New from University of Pittsburgh Neural Engineering Cross-Translation (UP NExT): PV interneurons don’t just control brain rhythms, they fine-tune blood flow too.
2P imaging + optogenetics, we found depth-specific vasoconstriction & dilation shaping both sensory-evoked & resting-state hemodynamics.
2P imaging + optogenetics, we found depth-specific vasoconstriction & dilation shaping both sensory-evoked & resting-state hemodynamics.
The University of Pittsburgh Neural Engineering Cross-Translation (UP NExT) Program is helping Americans & taxpayers by using Utah arrays to study brain signals. Insights from this work guide better use today and smarter designs for next-gen devices to restore movement & touch. #NIH #TaxpayerImpact
November 6, 2025 at 1:20 AM
The University of Pittsburgh Neural Engineering Cross-Translation (UP NExT) Program is helping Americans & taxpayers by using Utah arrays to study brain signals. Insights from this work guide better use today and smarter designs for next-gen devices to restore movement & touch. #NIH #TaxpayerImpact
Basic science is the rebar in brain tech.
From 2019-2022, NIH’s RFA-NS-20-006 funded the why behind implants that last 10 yrs, not 10 wks.
It ended in 2022, not because it failed, but because Academia/ DC grades on headlines, not foundations.
Demos dazzle. Basic science delivers.
#BuildToLast
From 2019-2022, NIH’s RFA-NS-20-006 funded the why behind implants that last 10 yrs, not 10 wks.
It ended in 2022, not because it failed, but because Academia/ DC grades on headlines, not foundations.
Demos dazzle. Basic science delivers.
#BuildToLast
November 3, 2025 at 11:48 AM
Basic science is the rebar in brain tech.
From 2019-2022, NIH’s RFA-NS-20-006 funded the why behind implants that last 10 yrs, not 10 wks.
It ended in 2022, not because it failed, but because Academia/ DC grades on headlines, not foundations.
Demos dazzle. Basic science delivers.
#BuildToLast
From 2019-2022, NIH’s RFA-NS-20-006 funded the why behind implants that last 10 yrs, not 10 wks.
It ended in 2022, not because it failed, but because Academia/ DC grades on headlines, not foundations.
Demos dazzle. Basic science delivers.
#BuildToLast