TK (Takashi DY) Kozai
bioniclab.bsky.social
TK (Takashi DY) Kozai
@bioniclab.bsky.social
Ernest E Roth Professor. Dept Bioengineering, University of Pittsburgh.
BionicLab.org
Neural Engineering; Neural Interfaces: Neurostimulation; Neurocomputation
This was driven by taxpayer-funded (#NIH) science. The return is clear: longer lasting implants, lower lifetime care costs, stronger rehab options for injured service members, and more U.S. jobs in high-tech biomedical engineering. #AmericanJobs #NIH #NSF
November 23, 2025 at 3:26 PM
Using a physics-based finite element model, we identified how small brain–electrode shifts create strain fields that correspond to future recording quality. This reveals mechanical failure in real-world scenarios before they appear clinically.
November 23, 2025 at 3:26 PM
📉 The core problem: even the best brain–computer interface electrodes slowly lose signal quality. This limits prosthetic control for veterans with limb loss, communication for people with paralysis, and long-term independence for many Americans.
November 23, 2025 at 3:26 PM
Bonus presentation from our new postdoc. Check out her PhD work and ask her what she's working on now. stim.bioniclab.org
November 15, 2025 at 4:57 PM
Visit us to see: #Oligodendrocyte Ca²⁺ dynamics, hypermyelination & FusOLcKO effects on hippocampal signaling, #Microglia responses to implants, vasomotor impairments, #NeuralGlider insertion metrics, & age-related laminar connectivity loss. Details: www.bioniclab.org/news/univers...
B.I.O.N.I.C. Lab - University of Pittsburgh Neural Engineering Cross-Translation @SfN2025
University of Pittsburgh Neural Engineering Cross-Translation (UP NExT) @SfN2025
www.bioniclab.org
November 15, 2025 at 4:05 PM
NIH-funded science that:
🇺🇸 Builds foundational knowledge for brain disease diagnostics
🎓 Trains next-gen neuroengineers
⚙️ Keeps the U.S. leading in neurotechnology innovation

#Neuroengineering #fMRI #NeurovascularCoupling #NIH #BrainResearch #ScienceForAmerica
November 10, 2025 at 12:41 AM
Small movements between the brain and the array create stress on tissue differently:
-Outer electrodes: Take the most direct mechanical stress, causing scarring.
-Inner electrodes: Stress on the edges can pinch blood vessels, reducing nutrients to neurons in the center, weakening them over time.
November 6, 2025 at 1:20 AM
45% of amputations = trauma (many vets).
This reuses FDA-cleared hardware → fast VA rollout.
↓ Falls ($50K each) = taxpayer ROI. UP NExT: Engineer → Test → Translate → Impact.
October 25, 2025 at 3:50 PM