Sebastian S. Cocioba
@atinygreencell.bsky.social
Flower Designer at Neoplants 🌺
Researcher at Binomica Labs
Degreeless Heathen
Petunia and Snapdragon Breeder
Open Lab Notebook: http://tinyurl.com/ATGCFFE
Researcher at Binomica Labs
Degreeless Heathen
Petunia and Snapdragon Breeder
Open Lab Notebook: http://tinyurl.com/ATGCFFE
Pinned
Sebastian's Biotech Bazaar
Designer of fine, hand-crafted, bespoke, and fully open source biotechnology tools for educators and researchers. Plasmids, lab equipment, cell lines, and seeds. An ever-growing collection of high qua...
ATinyGreenCell.com
Excited to announce some new plasmid offerings in my shop at atinygreencell.com! Here's a thread of the current catalog. All proceeds directly support my lab and my continued effort to build useful open-source tools. Feel free to get in touch if you want to know more. Please share! 💚
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Reposted by Sebastian S. Cocioba
Come work with us!! 2.5 year postdoc on HGT in plants.
Please share and get in touch if interested
www.jobs.ac.uk/job/DPQ418/r...
Please share and get in touch if interested
www.jobs.ac.uk/job/DPQ418/r...
Research Associate: Horizontal Gene Transfer at University of Sheffield
Searching for an academic job? Explore this Research Associate: Horizontal Gene Transfer opening on jobs.ac.uk! Click to view more details and browse other academic jobs.
www.jobs.ac.uk
November 28, 2025 at 8:06 PM
Come work with us!! 2.5 year postdoc on HGT in plants.
Please share and get in touch if interested
www.jobs.ac.uk/job/DPQ418/r...
Please share and get in touch if interested
www.jobs.ac.uk/job/DPQ418/r...
I can't wait to be able to run RT-qPCR in my lab!!!
Eagerly awaiting my Pocket qPCR to arrive. I can finally use my 50k units of reverse transcriptase I got from Gene and Cell Technologies a few years ago.
gaudi.ch/PocketPCR/in...
Eagerly awaiting my Pocket qPCR to arrive. I can finally use my 50k units of reverse transcriptase I got from Gene and Cell Technologies a few years ago.
gaudi.ch/PocketPCR/in...
qPocketPCR – The Ultra-Compact Real-Time PCR Thermocycler – PocketPCR
gaudi.ch
November 29, 2025 at 9:55 AM
I can't wait to be able to run RT-qPCR in my lab!!!
Eagerly awaiting my Pocket qPCR to arrive. I can finally use my 50k units of reverse transcriptase I got from Gene and Cell Technologies a few years ago.
gaudi.ch/PocketPCR/in...
Eagerly awaiting my Pocket qPCR to arrive. I can finally use my 50k units of reverse transcriptase I got from Gene and Cell Technologies a few years ago.
gaudi.ch/PocketPCR/in...
Reposted by Sebastian S. Cocioba
New preprint: 🚀🧬 Starship in the genome of the lichen fungus Xanthoria. Discovery of giant transposons Starships challenged what we thought we knew about fungal genomes. But what about Starships in #lichen fungi? Let us present Tangerine! 🖥️ 🧪 🦠 🧫 #SymbioSky doi.org/10.1101/2025...
November 28, 2025 at 2:20 PM
New preprint: 🚀🧬 Starship in the genome of the lichen fungus Xanthoria. Discovery of giant transposons Starships challenged what we thought we knew about fungal genomes. But what about Starships in #lichen fungi? Let us present Tangerine! 🖥️ 🧪 🦠 🧫 #SymbioSky doi.org/10.1101/2025...
Gonna try this excimer lamp from @nukit.bsky.social (thanks for donating one to my cause!) to kill off agrobacterium after co-culture as a means of antibiotic-free plant bioengineering. Agrobacterium resurgence is a huge pain and often we use frontline antibiotics to clear it away.
November 27, 2025 at 3:34 PM
Gonna try this excimer lamp from @nukit.bsky.social (thanks for donating one to my cause!) to kill off agrobacterium after co-culture as a means of antibiotic-free plant bioengineering. Agrobacterium resurgence is a huge pain and often we use frontline antibiotics to clear it away.
I find myself so deeply drawn to immense challenge in my craft. To be honest I never had an easy gig in my life, for better or worse, but the overlap of instinct, experience, and good experimentation is so deeply satisfying. Took forever to get here, but I'm savoring the struggle
November 27, 2025 at 4:35 AM
I find myself so deeply drawn to immense challenge in my craft. To be honest I never had an easy gig in my life, for better or worse, but the overlap of instinct, experience, and good experimentation is so deeply satisfying. Took forever to get here, but I'm savoring the struggle
Reposted by Sebastian S. Cocioba
Been trying to read this book loaned to me by @cawatran.bsky.social for months but ironically too distracted to finish it 🤣
November 26, 2025 at 7:26 PM
Been trying to read this book loaned to me by @cawatran.bsky.social for months but ironically too distracted to finish it 🤣
I just picked up a Pocket qPCR from the legendary Urs Gaudenz. Can't wait to finally have some gene expression tooling. $1000 with tarrifs and tax shipped to US.
gaudi.ch/PocketPCR/in...
gaudi.ch/PocketPCR/in...
qPocketPCR – The Ultra-Compact Real-Time PCR Thermocycler – PocketPCR
gaudi.ch
November 26, 2025 at 1:29 PM
I just picked up a Pocket qPCR from the legendary Urs Gaudenz. Can't wait to finally have some gene expression tooling. $1000 with tarrifs and tax shipped to US.
gaudi.ch/PocketPCR/in...
gaudi.ch/PocketPCR/in...
Reposted by Sebastian S. Cocioba
Genome sequence of the ornamental plant Digitalis purpurea reveals the molecular basis of flower color and morphology variation
doi.org/10.1101/2024...
doi.org/10.1101/2024...
Genome sequence of the ornamental plant Digitalis purpurea reveals the molecular basis of flower color and morphology variation
Digitalis purpurea (foxglove) is a widely distributed ornamental plant and the producer of the biomedical compound digoxin. Here, we present a long read sequencing-based genome sequence of a magenta f...
doi.org
November 26, 2025 at 5:30 AM
Genome sequence of the ornamental plant Digitalis purpurea reveals the molecular basis of flower color and morphology variation
doi.org/10.1101/2024...
doi.org/10.1101/2024...
Exploring herbicide-free selection of transgenic tissue using just RUBY and my eyes has been so interesting. Way more phenotypes of intensity at the callus stage. Currently teasing this promising lump of red in this otherwise bright green chamomile. Replating my darlings. 💚
November 25, 2025 at 11:18 PM
Exploring herbicide-free selection of transgenic tissue using just RUBY and my eyes has been so interesting. Way more phenotypes of intensity at the callus stage. Currently teasing this promising lump of red in this otherwise bright green chamomile. Replating my darlings. 💚
Toobberry is berrying again. Such toob. Very berry. So smol.
November 25, 2025 at 8:52 PM
Toobberry is berrying again. Such toob. Very berry. So smol.
The most exciting part of this new job at Neoplants is that I finally have some institutional support for my flower work. Its so unimaginably difficult to move forward without resources so I'm deeply thankful for that. I finally have some time to do more than just scrape by. 🌺🖌
November 25, 2025 at 8:46 PM
The most exciting part of this new job at Neoplants is that I finally have some institutional support for my flower work. Its so unimaginably difficult to move forward without resources so I'm deeply thankful for that. I finally have some time to do more than just scrape by. 🌺🖌
I like my wild-type wild and my experiments controlled. Messy blooms are the story of my life.
November 25, 2025 at 8:35 PM
I like my wild-type wild and my experiments controlled. Messy blooms are the story of my life.
Reposted by Sebastian S. Cocioba
Arabidopsis can be engineerded to smell as a rose! @nickdesnoyer.bsky.social and @atinygreencell.bsky.social that means we can also make it smell as a #Petunia!! #MetabolicEngineering #plantscience
www.sciencedirect.com/science/arti...
www.sciencedirect.com/science/arti...
Model-guided metabolic engineering of 2-phenylethanol in Arabidopsis
2-Phenylethanol (2-PE) is a natural aromatic compound with properties that make it a potential biological oxygenate for petroleum-derived gasoline. In…
www.sciencedirect.com
November 25, 2025 at 2:06 PM
Arabidopsis can be engineerded to smell as a rose! @nickdesnoyer.bsky.social and @atinygreencell.bsky.social that means we can also make it smell as a #Petunia!! #MetabolicEngineering #plantscience
www.sciencedirect.com/science/arti...
www.sciencedirect.com/science/arti...
The Ag ppl on LinkedIn are strangely helpful and kind. Between the endless bots and fake persona of that hellsite are islands of sincerity. Not sure how I feel about that now, lol.
November 24, 2025 at 12:54 PM
The Ag ppl on LinkedIn are strangely helpful and kind. Between the endless bots and fake persona of that hellsite are islands of sincerity. Not sure how I feel about that now, lol.
Reposted by Sebastian S. Cocioba
This kind of stuff is why I say that I worry that the tools of neuroscience are not properly vetted
“Our findings challenge the conventional focus on low-dimensional coding subspaces as a sufficient framework for understanding neural computations, demonstrating that dimensions previously considered task-irrelevant and accounting for little variance can have a critical role in driving behavior.”
Neural dynamics outside task-coding dimensions drive decision trajectories through transient amplification
Most behaviors involve neural dynamics in high-dimensional activity spaces. A common approach is to extract dimensions that capture task-related variability, such as those separating stimuli or choice...
www.biorxiv.org
November 23, 2025 at 3:02 PM
This kind of stuff is why I say that I worry that the tools of neuroscience are not properly vetted
Reposted by Sebastian S. Cocioba
🌶️🌶️🌶️
A gel-based artificial tongue can determine the spiciness of a wide range of foods
go.nature.com/4oafMqh
go.nature.com/4oafMqh
Synthetic tongue rates chillies’ heat — and spares human tasters
Gel-based device inspired by the cooling powers of milk assesses peppers whose burn ranges from mild to dangerous.
go.nature.com
November 24, 2025 at 12:41 PM
🌶️🌶️🌶️
Reposted by Sebastian S. Cocioba
Reposted by Sebastian S. Cocioba
Im a sucker for the copy on the RL website
November 23, 2025 at 3:33 PM
Im a sucker for the copy on the RL website
Behold, feeshpeepolmeeting. 🐟🧬🤝
Come join us in Heidelberg for the first German fish meeting 👩🔬👨🔬🧬🔬🐟🐠
November 23, 2025 at 5:10 AM
Behold, feeshpeepolmeeting. 🐟🧬🤝
Reposted by Sebastian S. Cocioba
Come join us in Heidelberg for the first German fish meeting 👩🔬👨🔬🧬🔬🐟🐠
November 22, 2025 at 6:08 PM
This very late bloomer is SO DARK. Here is a more typical bloom for comparison. Note the stark change in saturation between the corolla tube and actual petals of the dark mutant.
November 22, 2025 at 12:33 AM
This very late bloomer is SO DARK. Here is a more typical bloom for comparison. Note the stark change in saturation between the corolla tube and actual petals of the dark mutant.
A huge effort finally coming to fruition for B and their group. So excited to give this a whirl esp now that my cloning projects have ramped up substantially. Check this out 👇👇
Delighted to report that our group's passion project over the last 6+ years to make DNA cloning more accessible, efficient, and scalable using a software-assisted workflow called CloneCoordinate is now out in ACS Synbio!
pubs.acs.org/doi/10.1021/...
pubs.acs.org/doi/10.1021/...
CloneCoordinate: Open-Source Software for Collaborative DNA Construction
Custom DNA constructs have never been more common or important in the life sciences. Many researchers therefore devote substantial time and effort to molecular cloning, aided by abundant computer-aide...
pubs.acs.org
November 21, 2025 at 9:43 PM
A huge effort finally coming to fruition for B and their group. So excited to give this a whirl esp now that my cloning projects have ramped up substantially. Check this out 👇👇
The spinach seems lively today...
November 21, 2025 at 4:48 PM
The spinach seems lively today...
Exploring the living world, with whatever means you have, without any sifting for grander purpose or ulterior motives, is such a unique high. There is so much beauty and so many stories to tell around the proverbial campfire, and so many people are missing out.
Gotta fix this.
Gotta fix this.
November 21, 2025 at 2:47 PM
Exploring the living world, with whatever means you have, without any sifting for grander purpose or ulterior motives, is such a unique high. There is so much beauty and so many stories to tell around the proverbial campfire, and so many people are missing out.
Gotta fix this.
Gotta fix this.
Mom loved watching the pipetting robot run. Also peep the sport fishing shirt; my late dad's she uses as a gardening shirt.
November 20, 2025 at 5:32 PM
Mom loved watching the pipetting robot run. Also peep the sport fishing shirt; my late dad's she uses as a gardening shirt.