B Thuronyi (they/them)
@thuronyi.bsky.social
Synthetic biologist, V. natriegens booster, Sheets torturer & asst prof Chem @ Williams College
Reposted by B Thuronyi (they/them)
#microsky #phagesky #phage
Anyone who’s tried deleting prophages in the lab by HR knows the difficulties of the task. Here we have an example of how HR-mediated natural transformation might hit the same hurdle in a more native context.
academic.oup.com/mbe/article/...
Anyone who’s tried deleting prophages in the lab by HR knows the difficulties of the task. Here we have an example of how HR-mediated natural transformation might hit the same hurdle in a more native context.
academic.oup.com/mbe/article/...
Chromosomal Curing Drives an Arms Race Between Bacterial Transformation and Prophage
Abstract. Transformation occurs when bacteria import exogenous DNA via the competence machinery and integrate it into their genome through homologous recom
academic.oup.com
November 23, 2025 at 4:39 PM
#microsky #phagesky #phage
Anyone who’s tried deleting prophages in the lab by HR knows the difficulties of the task. Here we have an example of how HR-mediated natural transformation might hit the same hurdle in a more native context.
academic.oup.com/mbe/article/...
Anyone who’s tried deleting prophages in the lab by HR knows the difficulties of the task. Here we have an example of how HR-mediated natural transformation might hit the same hurdle in a more native context.
academic.oup.com/mbe/article/...
Reposted by B Thuronyi (they/them)
this looks like a dream come true for my lab. Can't wait to try it out!
November 21, 2025 at 9:52 PM
this looks like a dream come true for my lab. Can't wait to try it out!
Reposted by B Thuronyi (they/them)
A huge effort finally coming to fruition for B and their group. So excited to give this a whirl esp now that my cloning projects have ramped up substantially. Check this out 👇👇
Delighted to report that our group's passion project over the last 6+ years to make DNA cloning more accessible, efficient, and scalable using a software-assisted workflow called CloneCoordinate is now out in ACS Synbio!
pubs.acs.org/doi/10.1021/...
pubs.acs.org/doi/10.1021/...
CloneCoordinate: Open-Source Software for Collaborative DNA Construction
Custom DNA constructs have never been more common or important in the life sciences. Many researchers therefore devote substantial time and effort to molecular cloning, aided by abundant computer-aide...
pubs.acs.org
November 21, 2025 at 9:43 PM
A huge effort finally coming to fruition for B and their group. So excited to give this a whirl esp now that my cloning projects have ramped up substantially. Check this out 👇👇
I seem to be unspammed, so that was only a few hours -- yay!
A warm welcome from Bluesky, labeled as a spam account after writing 1 thread!!
November 21, 2025 at 9:22 PM
I seem to be unspammed, so that was only a few hours -- yay!
A warm welcome from Bluesky, labeled as a spam account after writing 1 thread!!
November 21, 2025 at 7:42 PM
A warm welcome from Bluesky, labeled as a spam account after writing 1 thread!!
Delighted to report that our group's passion project over the last 6+ years to make DNA cloning more accessible, efficient, and scalable using a software-assisted workflow called CloneCoordinate is now out in ACS Synbio!
pubs.acs.org/doi/10.1021/...
pubs.acs.org/doi/10.1021/...
CloneCoordinate: Open-Source Software for Collaborative DNA Construction
Custom DNA constructs have never been more common or important in the life sciences. Many researchers therefore devote substantial time and effort to molecular cloning, aided by abundant computer-aide...
pubs.acs.org
November 21, 2025 at 7:40 PM
Delighted to report that our group's passion project over the last 6+ years to make DNA cloning more accessible, efficient, and scalable using a software-assisted workflow called CloneCoordinate is now out in ACS Synbio!
pubs.acs.org/doi/10.1021/...
pubs.acs.org/doi/10.1021/...